Development of a bioreactor-based connective tissue production line (TISSUE REACTOR)

Informazioni relative al progetto

TISSUE REACTOR

ID dell’accordo di sovvenzione: G5RD-CT-2000-00282

Progetto chiuso

Data di avvio 1 Febbraio 2001

Data di completamento 31 Gennaio 2005

Finanziato da

• Programme for research technological development and demonstration on "Competitive and sustainable growth 1998-2002"

Costo totale € 2 881 000,00

Contributo UE € 2 381 000,00

Coordinato da

University of Ulm
Germany

Obiettivo

It is the aim of this project to engineer connective tissue in vitro and to demonstrate its applicability as a tissue substitute in vivo. To achieve this goal a continuous cultivation process based on a perfused fixed-bed bioreactor system and its components will be developed which allows the production of large quantities of three-dimensional (3-d) tissue cultures in combination with capillary-like prevascular precursors to form in vitro tissue constructs. The primary focus will be bone tissue, and bone tissue constructs will then subsequently be implanted in vivo to demonstrate their potential to improve current limitations in bone substitution surgery.

Campo scientifico

• engineering and technology › environmental biotechnology › bioremediation › bioreactors
• medical and health sciences › clinical medicine › surgery

Programma(i)

• FP5-GROWTH - Programme for research technological development and demonstration on "Competitive and sustainable growth 1998-2002"

Argomento(i)

• 1.1.3.-5. - RTD Activities of a Generic Nature : materials and their technologies for production and transformation and new and improved materials and production technologies in the steel field

Invito a presentare proposte

Data not available

Meccanismo di finanziamento

CSC - Cost-sharing contracts

Coordinatore

University of Ulm

• Contributo UE: Nessun dato
• Indirizzo: Albert-Einstein-Allee 11 ; 89070 Ulm ; Germania
• Costo totale: Nessun dato

Partecipanti (8)

BIOSCAN B.V.

Paesi Bassi

• Contributo UE: Nessun dato
• Indirizzo: 10,Prof. Bronkhorstlaan 10 bld.D ; 3723 MB BILTHOVEN
• Costo totale: Nessun dato

CAM IMPLANTS B.V.

Paesi Bassi

• Contributo UE: Nessun dato
• Indirizzo: Zernikedreef 6 ; 2333 CL LEIDEN
• Costo totale: Nessun dato

GBF - NATIONAL CENTRE FOR BIOTECHNOLOGY

Germania

• Contributo UE: Nessun dato
• Indirizzo: Mascheroder Weg 1 ; 38124 BRAUNSCHWEIG
• Costo totale: Nessun dato

MEREDOS GMBH

Germania

• Contributo UE: Nessun dato
• Indirizzo: 37,Alte Dorfstraat 37 ; 37120 BOVENDEN
• Costo totale: Nessun dato

MNEMOSCIENCE GMBH

Germania

• Contributo UE: Nessun dato
• Indirizzo: Pauwelsstrasse 19 ; 52074 AACHEN
• Costo totale: Nessun dato

UNIVERSITY OF AVEIRO

Portogallo

• Contributo UE: Nessun dato
• Indirizzo: Campo Universitario de Santiago ; 3810-193 AVEIRO
• Costo totale: Nessun dato

UNIVERSITY OF MANCHESTER

Regno Unito

• Contributo UE: Nessun dato
• Indirizzo: Oxford Road ; MANCHESTER
• Costo totale: Nessun dato

UNIVERSITY OF NOTTINGHAM

Regno Unito

• Contributo UE: Nessun dato
• Indirizzo: University Park ; NG7 2RD NOTTINGHAM
• Costo totale: Nessun dato