Single-cell spatiotemporal analysis of Mycobacterium tuberculosis responses to antibiotics within host microenvironments

Project Information

SpaTime_AnTB

Grant agreement ID: 892859

DOI 10.3030/892859

Project closed

EC signature date 27 February 2020

Start date 1 April 2020

End date 31 March 2022

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 224 933,76

EU contribution € 224 933,76

Coordinated by

THE FRANCIS CRICK INSTITUTE LIMITED
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion

Author(s): Elliott M. Bernard, Antony Fearns, Claudio Bussi, Pierre Santucci, Christopher J. Peddie, Rachel J. Lai, Lucy M. Collinson, and Maximiliano G. Gutierrez
Published in: Journal of Cell Science, 2021, ISSN 1477-9137
Publisher: The Compagny of Biologists
DOI: 10.1242/jcs.252973

Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

Author(s): Pierre Santucci, Daniel J. Greenwood, Antony Fearns, Kai Chen, Haibo Jiang, and Maximiliano G. Gutierrez
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-24127-3

Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis

Author(s): Pierre Santucci, Beren Aylan, Laure Botella, Elliott M. Bernard, Claudio Bussi, Enrica Pellegrino, Natalia Athanasiadi and Maximiliano G. Gutierrez
Published in: mBio, 2022, ISSN 2150-7511
Publisher: ASM
DOI: 10.1128/mbio.00117-22