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Tracking and Targeting Tumor States at single-cell resolution in real time in vivo

Publications

Deciphering functional tumor states at single-cell resolution.

Author(s): Vegliante R, Pastushenko I, Blanpain C.
Published in: EMBO J, 2021, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2021109221

The extracellular matrix dictates regional competence for tumour initiation

Author(s): Bansaccal N, Vieugue P, Sarate R, Song Y, Minguijon E, Miroshnikova YA, Zeuschner D, Collin A, Allard J, Engelman D, Delaunois AL, Liagre M, de Groote L, Timmerman E, Van Haver D, Impens F, Salmon I, Wickström SA, Sifrim A, Blanpain C.
Published in: Nature, Issue 2023 Nov 15., 2023, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-06740-y

Netrin-1 blockade inhibits tumour growth and EMT features in endometrial cancer

Author(s): Cassier PA, Navaridas R, Bellina M, Rama N, Ducarouge B, Hernandez-Vargas H, Delord JP, Lengrand J, Paradisi A, Fattet L, Garin G, Gheit H, Dalban C, Pastushenko I, Neves D, Jelin R, Gadot N, Braissand N, Léon S, Degletagne C, Matias-Guiu X, Devouassoux-Shisheboran M, Mery-Lamarche E, Allard J, Zindy E, Decaestecker C, Salmon I, Perol D, Dolcet X, Ray-Coquard I, Blanpain C*, Bernet A*, Mehlen P*
Published in: Nature, Issue 2023 Aug 2, 2023, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-06367-z

NR2F2 controls malignant squamous cell carcinoma state by promoting stemness and invasion and repressing differentiation

Author(s): Mauri M, Schepkens C, Lapouge G, Drogat B, Song Y, Pastushenko I, Rorive S, Blondeau J, Golstein S, Bareche Y, Miglianico M, Nkusi E, Rozzi M, Moers M, Brisebarre A, Raphael M, Dubois C, Allard J, Durdu B, Ribeiro F, Sotiriou C, Salmon I, Vakili J & Blanpain C
Published in: Nature Cancer, 2021, ISSN 2662-1347
Publisher: Springer Nature Ltd
DOI: 10.1038/s43018-021-00287-5

RHOJ controls EMT-associated resistance to chemotherapy

Author(s): Maud Debaugnies, Sara Rodríguez-Acebes, Jeremy Blondeau, Marie-Astrid Parent, Manuel Zocco, Yura Song, Viviane de Maertelaer, Virginie Moers, Mathilde Latil, Christine Dubois, Katia Coulonval, Francis Impens, Delphi Van Haver, Sara Dufour, Akiyoshi Uemura, Panagiota A. Sotiropoulou, Juan Méndez & Cédric Blanpain
Published in: Nature, Issue 2023 Mar 22, 2023, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-05838-7

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis.

Author(s): Pastushenko I, Mauri F, Song Y, de Cock F, Meeusen B, Swedlund B, Impens F, Van Haver D, Opitz M, Thery M, Bareche Y, Lapouge G, Vermeersch M, Van Eycke YR, Balsat C, Decaestecker C, Sokolow Y, Hassid S, Perez-Bustillo A, Agreda-Moreno B, Rios-Buceta L, Jaen P, Redondo P, Sieira-Gil R, Millan-Cayetano JF, Sanmatrtin O, D'Haene N, Moers V, Rozzi M, Blondeau J, Lemaire S, Scozzaro S, Janssens V, De
Published in: Nature, 2021, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-020-03046-1

Cancer cell plasticity during tumor progression, metastasis and response to therapy

Author(s): Pérez González, A, Bévant, Kevin, Blanpain, C
Published in: Nature Cancer, Issue 2023 Aug 3, 2023, ISSN 2662-1347
Publisher: Springer Nature
DOI: 10.1038/s43018-023-00595-y

Pharmacological targeting of netrin-1 inhibits EMT in cancer

Author(s): Lengrand J, Pastushenko I, Vanuytven S, Song Y, Venet D, Sarate RM, Bellina M, Moers V, Boinet A, Sifrim A, Rama N, Ducarouge B, Van Herck J, Dubois C, Scozzaro S, Lemaire S, Gieskes S, Bonni S, Collin A, Braissand N, Allard J, Zindy E, Decaestecker C, Sotiriou C, Salmon I, Mehlen P, Voet T, Bernet A, Blanpain C.
Published in: Nature, Issue 2023 Aug 2., 2023, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-06372-2

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