Deliverables
Completion of analyses of cortisol and other stress markers
Rapid volatilome method developed for toxicants
Development of a method and system to monitor volatile toxicants based on differential ion mobility spectrometry
Rapid volatilome method developed for microbiome analysesDevelopment of a method and system to monitor volatile organic compounds related to microbiome andor immunemediated diseases based on differential ion mobility spectrometry as described in Task 7
Multiarray system for antibody screeningDevelopment of portable low cost automatized multiarray system for key biomarkers as described in Task 72
Harmonization of existing data in clinical cohortsGeneration of data matrix including data from clinical cohorts
Identification of additionial end-points in clinical cohortsThe gaps in the end-point data will be filled and the number of end-points will be increased by analyzing islet autoantibodies, transglutaminase autoantibodies, allergen specific IgE, and by registry linkage.
Quality control proceduresProcedures for quality control of laboratory analyses and data integrity
Portable reader for the multiarray systemDevelopment of a portable customized optical reader for the readout of the IncaSlides, as described in Task 7.2.
High throughput immunosignature tool developedDevelopment of an antigen array for characterization of antibody responses to infections as described in Task 71
Plan for dissemination and exploitation of the results and innovations generated by HEDIMED, according to the Tasks of WP11.
Report 4 Joint Network Advisory Board - EPHOR/REMEDIA/HEDIMEDIdentify the members, mandate as well rules and work plan for NAB
Definitions and criteria for study endpointsGeneration of definitions and criteria for study end points in all cohorts.
Kick-off reportReport from the kick-off meeting
Final management structureFinalization of the management team structure that assists and advices the HEDIMED partners regarding administration and reporting and produces necessary reports
Ethical approval reportEnsurement that the all EU regulations (e.g. GDPR) will be followed in the analyses of samples and data in the present consortium
Procedures securing protection of personal dataProtection of personal identity of the study subjects using procedures legally accepted by member states. Creation of anonymized database to allow flexible analyses of the data by consortium members
Creation of publication guidelinesCreation of publication guidelines for the HEDIMED consortium covering scientific publications emerging from the project.
State-of-art reportComprehensive summary of current scientific state of the research in the field covered by HEDIMED.
Dissemination and Exploitation plan updatePlan update for dissemination and exploitation of the results and innovations generated by HEDIMED according to the Tasks of WP11
Data management plan completed as described in PART B 1.3.2.6 Data management, and Fig.8, and Task 10.4.
Construction of HEDIMED project web site
Publications
Author(s):
Demuru, Silvia, Hui Chai-Gao, Yevhen Shynkarenko, Nicola Hermann, Patricia-Daiana Boia, Peter Cristofolini, Bradley Petkus, Silvia Generelli, Samantha Paoletti, Stefano Cattaneo and Loïc Burr
Published in:
Sensors, 2024, ISSN 1424-8220
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/s24113280
Author(s):
Jacub Hurych, Elin Oscarsson, Åsa Håkanson, Kateřina Jirků-Pomajbíková, Milan Jirků, Carin Andrén Aronson, Ondřej Cinek, Daniel Agardh & the HEDIMED Investigator Group
Published in:
Paracites and Vectors, 2023, ISSN 1756-3305
Publisher:
BioMed Central
DOI:
10.1186/s13071-023-06027-1
Author(s):
Astrid Sevelsted, Casper-Emil Pedersen, Gözde Gürdeniz, Morten Rasmussen, Jörg Schullehner, Kalliroi Sdougkou, Jonathan W. Martin, Jessica Lasky-Su, Andreanne Morin, Carole Ober, Ann-Marie Schoos, Jakob Stokholm, Klaus Bønnelykke, Bo Chawes & Hans Bisgaard
Published in:
eBioMedicine, 2023, ISSN 2352-3964
Publisher:
Elsevier BV
DOI:
10.1016/j.ebiom.2023.104699
Author(s):
Wisnu Adi Wicaksono, Aisa Buko, Peter Kusstatscher, Aki Sinkkonen, Olli H. Laitinen, Suvi M. Virtanen, Heikki Hyöty, Tomislav Cernava, Gabriele Berg
Published in:
Food Microbiology, Issue Volume 108, December 2022, 104103, 2022, ISSN 0740-0020
Publisher:
Academic Press
DOI:
10.1016/j.fm.2022.104103
Author(s):
Wisnu Adi Wicaksono, Tomislav Cernava, Birgit Wassermann, Ahmed Abdelfattah, Maria J. Soto-Giron, Gerardo V. Toledo, Suvi M. Virtanen, Mikael Knip, Heikki Hyöty & Gabriele Berg
Published in:
Gut Microbes, 2023, ISSN 1949-0984
Publisher:
Taylor and Francis Group
DOI:
10.1080/19490976.2023.2258565
Author(s):
Noora Nurminen, Damiano Cerrone, Jussi Lehtonen, Anirudra Parajuli, Marja Roslund, Maria Lönnrot, Jorma Ilonen, Jorma Toppari, Riitta Veijola, Mikael Knip, Juho Rajaniemi, Olli H. Laitinen, Aki Sinkkonen, Heikki Hyöty
Published in:
Diabetes Care, Issue 44/7, 2021, Page(s) 1506-1514, ISSN 0149-5992
Publisher:
American Diabetes Association
DOI:
10.2337/dc20-1719
Author(s):
Laiho, Jutta E; Laitinen, Olli H; Malkamäki, Johannes; Puustinen, Leena; Sinkkonen, Aki; Pärkkä, Juha; Hyöty, Heikki
Published in:
Environmental Epidemioogy, Issue 2, 2022, ISSN 2474-7882
Publisher:
Wolters Kluwer Health
Author(s):
German Tapia, Kateřina Chudá, Christian R. Kahrs, Lars C. Stene, Lenka Kramna, Karl Mårild, Trond Rasmussen, Kjersti S. Rønningen, Ondřej Cinek, Ketil Størdal
Published in:
American Journal of Gastroenterology, Issue 116/4, 2021, Page(s) 788-795, ISSN 0002-9270
Publisher:
Blackwell Publishing Inc.
DOI:
10.14309/ajg.0000000000001003
Author(s):
Marja I. Roslund; Anirudra Parajuli; Nan Hui; Riikka Puhakka; Mira Grönroos; Laura Soininen; Noora Nurminen; Sami Oikarinen; Ondřej Cinek; Lenka Kramná; Anna-Mari Schroderus; Olli H. Laitinen; Tuure Kinnunen; Heikki Hyöty; Aki Sinkkonen; Damiano Cerrone; Mira Grönroos; Olli H. Laitinen; Anna Luukkonen; Iida Mäkelä; Noora Nurminen; Sami Oikarinen; Anirudra Parajuli; Riikka Puhakka; Marja I.
Published in:
Ecotoxicology and Environmental Safety, Issue 4, 2022, ISSN 1090-2414
Publisher:
Academic Press Inc.
DOI:
10.1016/j.ecoenv.2022.113900
Author(s):
Wisnu Adi Wicaksono; Aisa Buko; Peter Kusstatscher; Tomislav Cernava; Aki Sinkkonen; Olli H. Laitinen; Suvi M. Virtanen; Heikki Hyöty; Gabriele Berg
Published in:
Microbial Ecology, Issue 2, 2022, ISSN 0095-3628
Publisher:
Springer Verlag
DOI:
10.1007/s00248-022-02157-8
Author(s):
Eliska Jenickova, Carin Andrén Aronsson,
Anna Mascellani Bergo, Ondrej Cinek, Jaroslav Havlik, Daniel Agardh.
Published in:
Frontiers in Nutrition., 2023, ISSN 2296-861X
Publisher:
Frontiers Media S.A
DOI:
10.3389/fnut.2023.1183963
Author(s):
Tiia Voor, Meelis Pärtel, Aleksandr Peet, Liisa Saare, Heikki Hyöty, Mikael Knip, John Davison, Martin Zobel, Vallo Tillmann.
Published in:
Clinical & Experimental Allergy., 2023, ISSN 1365-2222
Publisher:
John Wiley & Sons Ltd
DOI:
10.1111/cea.14317
Author(s):
Leena Hakola, Nicolai A Lund-Blix, Hanna-Mari Takkinen, Heli Tapanainen, Sari Niinistö, Tuuli E Korhonen, Lars C Stene, Heikki Hyöty, Jorma Toppari, Jorma Ilonen, Mikael Knip, Riitta Veijola, Suvi M Virtanen & HEDIMED Investigator group.
Published in:
Clinical Nutrition ESPEN, 2024, ISSN 2405-4577
Publisher:
European Society for Clinical Nutrition and Metabolism (ESPEN)
DOI:
10.1016/j.clnesp.2024.05.001
Author(s):
Barannik Emilia
Published in:
2022
Publisher:
Aalto University /CHEM
Author(s):
Kristiina, Dahl
Published in:
2021
Publisher:
Aalto University / CHEM
Author(s):
Mäkinen, Jani
Published in:
2023
Publisher:
Aalto University /School of Science
Author(s):
Nicolai A. Lund-Blix, Anne A. Bjerregaard, German Tapia, View ORCID ProfileKetil Størdal, Anne Lise Brantsæter, Marin Strøm, Thorhallur I. Halldorsson, Charlotta Granstrøm, Jannet Svensson, Geir Joner, Torild Skrivarhaug, Pål R. Njølstad, View ORCID ProfileSjurdur F. Olsen, View ORCID ProfileLars C. Stene
Published in:
2023
Publisher:
medRxiv
DOI:
10.1101/2023.11.23.23297665
Author(s):
Lars C. Stene, Jill M. Norris, and Marian J. Rewers
Published in:
2023
Publisher:
National Institute of Diabetes and Digestive and Kidney Diseases
Author(s):
Valeriia Dotsenko; Amir-Babak Sioofy-Khojine; Heikki Hyöty; Keijo Viiri
Published in:
Celiac Disease ISBN: 9780443192029, Issue 13, 2023
Publisher:
Elsevier BV
DOI:
10.1016/bs.mcb.2023.01.008
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