New Generation Cell Therapy: Bioartificial Pancreas to Cure Type 1 Diabetes

Rezultaty

ACCEL will create a communication portfolio of updated VANGUARD print visual and media information and documentation including factsheets brochures and posters and visual content will be developed to offer information about the project in a condensed form that can be handed out during various events and downloaded from the project website

VANGUARD Stakeholder Engagement and Dissemination Assessment Reports

To asses the implementation and impact of the stakeholder engagement and dissemination activities, ACCEL will monitor and document (D9.4, M48) the implemented measures to assess the individual activities and adapt any activities where required to facilitate outreach and impact M24 and 48)

ELSA Training Manual

Training of VANGUARD researchers in M6, in particular newly recruited staff, on the ethical implications and safety requirements involved in regenerative medicine in general and the therapy developed during the VANGUARD project. The existing literature will be reviewed, experts in bioethics consulted, and together with partners we will develop a training manual.

Project website

To support aforementioned dissemination and communication activities throughout the duration of the project, ACCEL will set up and maintain the project website, which will notably function as the main source of information and resources related to the project, partners, latest developments, publications and public deliverables for all stakeholders.

Publikacje

Vascularized endocrine pancreas for type 1 diabetes

Autorzy: Bellofatto, Kevin; Lebreton, Fanny; Fonseca, Laura Mar; Hanna, Reine; Bignard, Juliette; Galvan, Victor; Peloso, Andrea; Berney, Thierry; Compagnon, Philippe; VANGUARD Consortium; Berishvili, Ekaterine
Opublikowane w: Transplantation, Numer 107, 2023, Strona(/y) 58
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/01.tp.0000994052.77218.10

Ethics of Early Clinical Trials of Bio-Artificial Organs

Autorzy: Bunnik, E.M., de Jongh, D. and Massey, E.
Opublikowane w: Transplant International, Numer 35, 2022, Strona(/y) 10621, ISSN 0934-0874
Wydawca: Frontiers Publishing Partnerships
DOI: 10.3389/ti.2022.10621

Generation of Prevascularized Endocrine Constructs to Treat Type 1 Diabetes

Autorzy: Bellofatto K, Lebreton F, Wassmer CH Fonseca L, Hanna R, Berishvili E.
Opublikowane w: Transplantation, Numer 9, 2022
Wydawca: Lippincott Williams & Wilkins
DOI: 10.1097/01.tp.0000885936.38573.32

Hydrogel-based, prevascularized, retrievable endocrine construct to treat Type 1 Diabetes

Autorzy: Bellofatto K, Lebreton F, Hanna R, Fonseca L M, Bignard J, Galvan V, Peloso A, Berney TH, Compagnon PH, VANGUARD Consortium, Berishvili E.
Opublikowane w: Transplantation, Numer 107, 2023, Strona(/y) 57
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/01.tp.0000994048.59940.dd

Mechanisms of Immunomodulation and Cytoprotection Conferred to Pancreatic Islet by Human Amniotic Epithelial Cells

Autorzy: Lebreton F, Hanna R, Wassmer CH, Bellofatto K, Perez L, Othenin-Girard V, de Tejada BM, Cohen M, Berishvili E.
Opublikowane w: Stem Cell Reviews and Reports, Numer 18, 2021, Strona(/y) 346-359, ISSN 1550-8943
Wydawca: Springer Verlag
DOI: 10.1007/s12015-021-10269-w

Formation of Re-Aggregated Neonatal Porcine Islet Clusters Improves In Vitro Function and Transplantation Outcome

Autorzy: Honarpisheh M, Lei Y, Zhang Y, Pehl M, Kemter E, Lange A, Wolf E, Wolf-van Buerck L, VANGUARD consortium, Seissler S.
Opublikowane w: Transplant International, Numer 35, 2022, ISSN 1432-2277
Wydawca: Frontiers
DOI: 10.3389/ti.2022.10697

Targeting Toll-Like Receptor 4: a promising strategy to prevent type 1 diabetes occurrence or recurrence

Autorzy: Alibashe-Ahmed M., Berney T., Giovannoni L., Berishvili E.
Opublikowane w: CellR4, Numer 8, 2020, ISSN 2329-7042
Wydawca: Verduci International
DOI: 10.32113/cellr4_20205_2850

Regulatory Challenges at the Intersection of Cellular and Medical Device Therapies in Europe: The Case of the Bioartificial Pancreas

Autorzy: Cronin AJ, Thom RL.
Opublikowane w: Law, Technology and Human, Numer 5(2), 2023, ISSN 2652-4074
Wydawca: QUT
DOI: 10.5204/lthj.3118

Immunomodulatory Properties of Amniotic Membrane Derivatives and Their Potential in Regenerative Medicine

Autorzy: Charles-Henri Wassmer, Ekaterine Berishvili
Opublikowane w: Current Diabetes Reports, Numer 20/8, 2020, Strona(/y) 31, ISSN 1534-4827
Wydawca: Current Science Inc.
DOI: 10.1007/s11892-020-01316-w

Generation of insulin‐secreting organoids: a step toward engineering and transplanting the bioartificial pancreas

Autorzy: Charles‐Henri Wassmer, Fanny Lebreton, Kevin Bellofatto, Domenico Bosco, Thierry Berney, Ekaterine Berishvili
Opublikowane w: Transplant International, Numer 33/12, 2020, Strona(/y) 1577-1588, ISSN 0934-0874
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/tri.13721

Organoids: a systematic review of ethical issues

Autorzy: Dide de Jongh, Emma K. Massey , the VANGUARD consortium*, Eline M. Bunnik
Opublikowane w: Stem Cell Research & Therapy, Numer 13, 2022, Strona(/y) 337, ISSN 1757-6512
Wydawca: BioMed Central
DOI: 10.1186/s13287-022-02950-9

Treatment of COVID-19 Pneumonia: the Case for Placenta-derived Cell Therapy

Autorzy: Ekaterine Berishvili, Laurent Kaiser, Marie Cohen, Thierry Berney, Hanne Scholz, Yngvar Floisand, Jonas Mattsson
Opublikowane w: Stem Cell Reviews and Reports, Numer 17/1, 2021, Strona(/y) 63-70, ISSN 2629-3277
Wydawca: Springer
DOI: 10.1007/s12015-020-10004-x

Early-Phase Clinical Trials of Bio-Artificial Organ Technology: A Systematic Review of Ethical Issues

Autorzy: de Jongh, D., Massey, E. K., Cronin, A. J., Schermer, M. H. N., Bunnik, E. M. and the VANGUARD Consortium
Opublikowane w: Transplant International, Numer 14322277, 2022, ISSN 1432-2277
Wydawca: Frontiers Publishing Partnership
DOI: 10.3389/ti.2022.10751

Engineering of Primary Pancreatic Islet Cell Spheroids for Three-dimensional Culture or Transplantation: A Methodological Comparative Study

Autorzy: Charles-Henri Wassmer, Kevin Bellofatto, Lisa Perez, Vanessa Lavallard, David Cottet-Dumoulin, Sanda Ljubicic, Géraldine Parnaud, Domenico Bosco, Ekaterine Berishvili, Fanny Lebreton
Opublikowane w: Cell Transplantation, Numer 29, 2020, Strona(/y) 096368972093729, ISSN 0963-6897
Wydawca: Cognizant Communication Corp.
DOI: 10.1177/0963689720937292

Efficient and safe correction of hemophilia A by lentiviral vector-transduced BOECs in an implantable device

Autorzy: Olgasi, C., Borsotti, C., Merlin, S., Bergmann, T., Bittorf, P., Adewoye, A. B., Wragg, N., Patterson, K., Calabria, A., Benedicenti, F., Cucci, A., Borchiellini, A., Pollio, B., Montini, E., Mazzuca, D. M., Zierau, M., Stolzing, A., Toleikis, P., Braspenning, J., & Follenzi, A.
Opublikowane w: Molecular Therapy - Methods & Clinical Development, Numer 23, 2021, Strona(/y) 551-566, ISSN 2329-0501
Wydawca: Cell Press
DOI: 10.1016/j.omtm.2021.10.015

Legal and Regulatory Challenges for Emerging Regenerative Medicine Solutions for Diabetes

Autorzy: Thom RL, Cronin AJ; VANGUARD Consortium.
Opublikowane w: Transplantation, Numer 9, 2023, ISSN 0041-1337
Wydawca: Lippincott Williams & Wilkins Ltd.
DOI: 10.1097/tp.0000000000004797

Clinical Translation of Bio-Artificial Pancreas Therapies: Ethical, Legal and Psychosocial Interdisciplinary Considerations and Key Recommendations

Autorzy: de Jongh D, Thom RL, Cronin AJ, Bunnik EM, Massey EK.
Opublikowane w: Transplant international, 2023, ISSN 1432-2277
Wydawca: Frontiers
DOI: 10.3389/ti.2023.11705

From islet of Langerhans transplantation to the bioartificial pancreas

Autorzy: Thierry Berney; Charles H. Wassmer; Fanny Lebreton; Kevin Bellofatto; Laura Mar Fonseca; Juliette Bignard; Reine Hanna; Andrea Peloso; Ekaterine Berishvili
Opublikowane w: La Presse Médicale, Numer 9, 2022, ISSN 0755-4982
Wydawca: Elsevier Masson
DOI: 10.1016/j.lpm.2022.104139

Therapeutic potential of fetal liver cell transplantation in hemophilia A mice

Autorzy: Simone, Merlin; Saicharan, Akula; Alessia, Cottonaro; Tamara, Garcia-Leal; Luis Javier, Serrano; Ester, Borroni; Vakhtang, Kalandadze; Rocio, Galiano; Chiara, Borsotti; Antonio, Liras; María José, Sanchez; Antonia, Follenzi
Opublikowane w: Haematologica, Numer 6, 2023, Strona(/y) 1544-1554, ISSN 1592-8721
Wydawca: Ferrata Storti Foundation
DOI: 10.3324/haematol.2022.282001

Guidelines to Analyze Preclinical Studies Using Perinatal Derivatives

Autorzy: Pires, Salomé; Bollini, Sveva; Botelho, Maria Filomena; Lang-Olip, Ingrid; Ponsaerts, Peter; Balbi, Carolina; Lange-Consiglio, Anna; Fénelon, Mathilde; Mojsilović, Slavko; Cremonesi, Fausto; Bugarski, Diana; Berishvili, Ekaterine; Gazouli, Maria; Gellhaus, Alexandra; Kerdjoudj, Halima; Schoeberlein, Andreina
Opublikowane w: Methods and Protocols, 2023, ISSN 2409-9279
Wydawca: MDPI
DOI: 10.3390/mps6030045

Bioengineering the Vascularized Endocrine Pancreas: A Fine-Tuned Interplay Between Vascularization, Extracellular-Matrix-Based Scaffold Architecture, and Insulin-Producing Cells

Autorzy: Pignatelli C, Campo F, Neroni A, Piemonti L and Citro A
Opublikowane w: Transplant International, Numer 14322277, 2022, ISSN 1432-2277
Wydawca: Frontiers
DOI: 10.3389/ti.2022.10555

Advances and challenges of endocrine pancreas bioengineering

Autorzy: Hanna, R., & Berishvili, E.
Opublikowane w: Current Opinion in Endocrine and Metabolic Research, Numer 23, 100320, 2022, ISSN 2451-9650
Wydawca: Elsevier Ltd.
DOI: 10.1016/j.coemr.2022.100320

I’ve got you under my skin

Autorzy: Thierry Berney, Ekaterine Berishvili
Opublikowane w: Nature Metabolism, Numer 2/10, 2020, Strona(/y) 993-994, ISSN 2522-5812
Wydawca: Nature Research
DOI: 10.1038/s42255-020-0268-8

Bio-Engineering of Pre-Vascularized Islet Organoids for the Treatment of Type 1 Diabetes

Autorzy: Wassmer, C.H., Lebreton, F., Bellofatto, K., Perez, L., Cottet-Dumoulin, D., Andres, A., Bosco, D., Berney, T., Othenin-Girard, V., Martinez De Tejada, B., Cohen, M., Follenzi, A., Berishvili, E., and the VANGUARD Consortium
Opublikowane w: Transplant International, Numer 35, 2022, ISSN 1432-2277
Wydawca: Frontiers
DOI: 10.3389/ti.2021.10214

Organoïdes sécréteurs d’insuline

Autorzy: Fanny Lebreton, Charles-Henri Wassmer, Kevin Belofatto, Thierry Berney, Ekaterine Berishvili
Opublikowane w: médecine/sciences, Numer 36/10, 2020, Strona(/y) 879-885, ISSN 0767-0974
Wydawca: Editions E D K
DOI: 10.1051/medsci/2020129

Rezultaty

Publikacje

Udostępnij tę stronę

Pobierz