EXposome Powered tools for healthy living in urbAN SEttings

Deliverables

Report describing tools and maps for the social environment

This report will describe the tools and maps that will be used in EXPANSE to quantify the social environment component of the External Exposome

Report on residential relocation in existing cohorts
Report describing tools and maps for the physico-chemical environment

This report will describe the tools and maps that will be used in EXPANSE to quantify the physicochemical environment component of the External Exposome

List of Working Groups and ToR for the WGs

A first set of working groups will be made and Term of Reference for the WGs will be specified including the selection of work group leaders coleads and members

Report on measurement error correction methodology

Report in which a new measurement error correction methodology applicable to Exposome studies is described

Report on the external Exposome results for primary CMPD outcomes

Report describing results from analyses in which association of the External Exposome with primary CMPD outcomes is assessed

Report describing the first meeting to discuss the design of the long-term research infrastructure

Report describing the first meeting to discuss the design of the longterm research infrastructure

Handover document to next coordinating team

Document summarising network activities and ongoing activities to facilitate a smooth transition to the next team. This document will include concise reports from working groups.

Report describing the tools to identify Expo-types and their internal drivers
Report describing tools and maps for the built environment

Report describing tools and maps for the built environment component of the External Exposome

Report on agent-based modelling of prevention strategies

Report on agent-based modelling to assess the impact of Exposome prevention strategies

Ethics by Design recommendations reports (months 12, 24, 36, 48 and 60)

Ethics by Design recommendations reports (months 12, 24, 36, 48 and 60), incorporating the

Report describing tools and maps for the food environment

This report will describe the tools and maps that will be used in EXPANSE to quantify the food environment component of the External Exposome

EXPANSE Website and social media accounts
EXPANSE Brochure

Publications

The ethical aspects of exposome research: a systematic review

Author(s): CW Safarlou, KR Jongsma, R Vermeulen, AL Bredenoord
Published in: Exposome, Issue 2023, 2023, ISSN 2635-2265
Publisher: Oxford University Press
DOI: 10.1093/exposome/osad004

Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking

Author(s): Petrovic D, Bodinier B, Dagnino S, Whitaker M, Karimi M, Campanella G, Haugdahl Nost T, Polidoro S, Palli D, Krogh V, Tumino R, Sacerdote C, Panico S, Lund E, Dugue PA, Giles GG, Severi G, Southey M, Vineis P, Stringhini S, Bochud M, Sandanger TM, Vermeulen RCH, Guida F, Chadeau-Hyam M.
Published in: European Journal of Epidemiology, 2022, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-022-00877-2

Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England

Author(s): Elliott P, Eales O, Steyn N, Tang D, Bodinier B, Wang H, Elliott J, Whitaker M, Atchison C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Ward H, Darzi A, Cooke GS, Donnelly CA, Chadeau-Hyam M
Published in: Science, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abq4411

Automated calibration for stability selection in penalised regression and graphical models

Author(s): Barbara Bodinier, Sarah Filippi, Therese Haugdahl Nøst, Julien Chiquet, Marc Chadeau-Hyam
Published in: Journal of the Royal Statistical Society Series C: Applied Statistics,, 2023, ISSN 1467-9876
Publisher: Oxford University Press

Effects of pesticide exposure on oxidative stress and DNA methylation urinary biomarkers in Czech adults and children from the CELSPAC-SPECIMEn cohort

Author(s): Tomas Janos, Ilse Ottenbros,Lucie Blahov, Petr Senka, Libor Sulca, Nina Palesova, Jessica Sheardova, Jelle Vlaanderen, Pavel Cupr
Published in: Environmental Research, Issue Volume 222 115368, 2023, ISSN 1096-0953
Publisher: Elsevier
DOI: 10.1016/j.envres.2023.115368

Agent-based modeling of urban exposome interventions: prospects, model architectures, and methodological challenges

Author(s): Tabea Sonnenschein, Simon Scheider, G Ardine de Wit, Cathryn C Tonne, Roel Vermeulen
Published in: Exposome, Issue Volume 2 / 2022, 2022, ISSN 2635-2265
Publisher: Oxford University Press
DOI: 10.1093/exposome/osac009

Residential relocation to assess impact of changes in the living environment on cardio-respiratory health: A narrative literature review with considerations for exposome research

Author(s): Apolline Saucy, Natalia Ortega, Cathryn Tonne
Published in: Environmental Research, Issue Volume 244 ; 2024, 2024, ISSN 0013-9351
Publisher: Academic Press
DOI: 10.1016/j.envres.2023.117890

A Knowledge Transfer Approach to Map Long-Term Concentrations of Hyperlocal Air Pollution from Short-Term Mobile Measurements

Author(s): Yuan, Z., Kerckhoffs, J., Hoek, G., & Vermeulen, R.
Published in: Environmental Science & Technology, Issue Volume 56 / 2022, 2022, Page(s) 13820 - 13828, ISSN 1520-5851
Publisher: ACS Publications
DOI: 10.1021/acs.est.2c05036

Mixed-Effects Modeling Framework for Amsterdam and Copenhagen for Outdoor NO2 Concentrations Using Measurements Sampled with Google Street View Cars

Author(s): Jules Kerckhoffs*, Jibran Khan, Gerard Hoek, Zhendong Yuan, Thomas Ellermann, Ole Hertel, Matthias Ketzel, Steen Solvang Jensen, Kees Meliefste, and Roel Vermeulen
Published in: Environmental Science and Technology, Issue 2022, 2022, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.1c05806

Predictive symptoms for COVID-19 in the community: REACT-1 study of over 1 million people

Author(s): Joshua Elliott, Matthew Whitaker, Barbara Bodinier, Oliver Eales, Steven Riley, Helen Ward, Graham Cooke, Ara Darzi, Marc Chadeau-Hyam, Paul Elliott
Published in: PLOS Medicine, Issue 18/9, 2021, Page(s) e1003777, ISSN 1549-1676
Publisher: PLOS
DOI: 10.1371/journal.pmed.1003777

LUR modeling of long-term average hourly concentrations of NO2 using hyperlocal mobile monitoring data

Author(s): Zhendong Yuan, Youchen Shen, Gerard Hoek, Roel Vermeulen, Jules Kerckhoffs
Published in: Science of The Total Environment, Issue Volume 922, 20 April 2024, 2024, Page(s) 171251, ISSN 1879-1026
Publisher: Elsevier
DOI: 10.1016/j.scitotenv.2024.171251

Allergies to food and airborne allergens in children and adolescents: role of epigenetics in a changing environment.

Author(s): Melén, E., Koppelman, G. H., Vicedo-Cabrera, A. M., Andersen, Z. J., & Bunyavanich, S.
Published in: The Lancet Child & Adolescent Health, Issue Volume 6 / 2022, 2022, Page(s) 810 - 819, ISSN 2352-4642
Publisher: Elsevier
DOI: 10.1016/s2352-4642(22)00215-2

Monthly average air pollution models using geographically weighted regression in Europe from 2000 to 2019

Author(s): Youchen Shen, Kees de Hoogh, Oliver Schmitz, Nick Clinton, Karin Tuxen-Bettman, Jørgen Brandt, Jesper H. Christensen, Lise M. Frohn, Camilla Geels, Derek Karssenberg, Roel Vermeulen, Gerard Hoek
Published in: Science of The Total Environment, Issue Volume 918 March 2024, 2024, ISSN 1879-1026
Publisher: Elsevier
DOI: 10.1016/j.scitotenv.2024.170550

Machine learning approaches to characterize the obesogenic urban exposome

Author(s): Haykanush Ohanyan, Lützen Portengen, Anke Huss, Eugenio Traini, Joline W.J. Beulens, Gerard Hoek, Jeroen Lakerveld, Roel Vermeulen,
Published in: Environment International, Issue Volume 158 / 2022, 2021, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.107015

Environmental risk factors of type 2 diabetes—an exposome approach

Author(s): Joline W. J. Beulens, Maria G. M. Pinho, Taymara C. Abreu, Nicole R. den Braver, Thao M. Lam, Anke Huss, Jelle Vlaanderen, Tabea Sonnenschein, Noreen Z. Siddiqui, Zhendong Yuan, Jules Kerckhoffs, Alexandra Zhernakova, Milla F. Brandao Gois & Roel C. H. Vermeulen
Published in: Diabetologia, Issue Volume 65 / 2022, 2021, Page(s) 263 - 274, ISSN 1432-0428
Publisher: Journal of the European Association for the Study of Diabetes (EASD).
DOI: 10.1007/s00125-021-05618-w

Socioeconomic distribution of food outlet availability through online food delivery services in seven European countries: A cross-sectional study

Author(s): Jody C. Hoenink, Yuru Huang, Matthew Keeble, Joreintje D. Mackenbach, Maria GM. Pinho, Thomas Burgoine, Jean Adams
Published in: Health & Place, Issue Volume 84, November 2023, 2023, Page(s) 103135, ISSN 1873-2054
Publisher: Elsevier
DOI: 10.1016/j.healthplace.2023.103135

Dynamics of a national Omicron SARS-CoV-2 epidemic during January 2022 in England

Author(s): Elliott P, Eales O, Bodinier B, Tang D, Wang H, Jonnerby J, Haw D, Elliott J, Whitaker M, Walters CE, Atchison C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Ward H, Darzi A, Cooke GS, Chadeau-Hyam M, Donnelly CA
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-32121-6

Disentangling associations between multiple environmental exposures and all-cause mortality: an analysis of European administrative and traditional cohorts

Author(s): Konstantina Dimakopoulou, Federica Nobile Jeroen de Bont, Kathrin Wolf, Danielle Vienneau, Dorina Ibi, Fabián Coloma, Regina Pickford, Christofer Åström, Johan Nilsson Sommar, Maria-Iosifina Kasdagli, Kyriakos Souliotis, Anastasios Tsolakidis, Cathryn Tonne, Erik Melén, Petter Ljungman, Kees de Hoogh Roel C. H. Vermeulen, Jelle J. Vlaanderen, Klea Katsouyanni, Massimo Stafoggia and Evangelia S
Published in: Frontiers in Epidemiology, Issue 2023, 2024, Page(s) 3:1328188., ISSN 2674-1199
Publisher: Frontiers
DOI: 10.3389/fepid.2023.1328188

Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease

Author(s): Jelle Vlaanderen, Kees de Hoogh, Gerard Hoek, Annette Peters, Nicole Probst-Hensch, Augustin Scalbert, Erik Melén, Cathryn Tonne, G. Ardine de Wit, Marc Chadeau-Hyam, Klea Katsouyanni, Tõnu Esko, Karin R. Jongsma, Roel Vermeulen
Published in: Environmental Epidemiology, Issue 5/4, 2021, Page(s) e162, ISSN 2474-7882
Publisher: Wolters Kluwer Health
DOI: 10.1097/ee9.0000000000000162

Merging the exposome into an integrated framework for “omics” sciences.

Author(s): Elliott J. Price, Chiara M. Vitale, Gary W. Miller, Arthur David, Robert Barouki, Karine Audouze, Douglas I. Walker, Jean-Philippe Antignac, Xavier Coumoul, Vincent Bessonneau, Jana Klánová,
Published in: iScience, Issue Volume 25 / 2022, 2022, ISSN 2589-0042
Publisher: 2589-0042
DOI: 10.1016/j.isci.2022.103976

The human microbial exposome: expanding the Exposome-Explorer database with gut microbial metabolites.

Author(s): Vanessa Neveu, Geneviève Nicolas, Adam Amara, Reza M. Salek, Augustin Scalbert
Published in: Scientific reports, Issue Volume 13 / 2023, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-26366-w

A State-of-the-Science Review on High-Resolution Metabolomics Application in Air Pollution Health Research: Current Progress, Analytical Challenges, and Recommendations for Future Direction

Author(s): Donghai Liang, Zhenjiang Li, Jelle Vlaanderen, Ziyin Tang, Dean P Jones , Roel Vermeulen , Jeremy A Sarnat
Published in: Environ Health Perspect, Issue 2023 May;131(5), 2023, Page(s) 56002, ISSN 0091-6765
Publisher: US Department of Health and Human Services
DOI: 10.1289/ehp118

Ultra-processed food consumption patterns among older adults in the Netherlands and the role of the food environment

Author(s): Pinho MGM, Lakerveld J, Harbers MC, Sluijs I, Vermeulen R, Huss A, Boer JMA, Verschuren WMM, Brug J, Beulens JWJ, Mackenbach JD
Published in: European Journal of Nutrition, Issue Volume 60 / 2021, 2020, Page(s) 2567 - 2580, ISSN 1436-6215
Publisher: Springer Nature
DOI: 10.1007/s00394-020-02436-5

Hallmarks of environmental insults

Author(s): Annette Peters, Tim S. Nawrot, Andrea A. Baccarelli
Published in: Cell, Issue 184/6, 2021, Page(s) 1455-1468, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.01.043

Narrative review of citizen science in environmental epidemiology: Setting the stage for co-created research projects in environmental epidemiology

Author(s): Frederique Froeling, Florence Gignac, Gerard Hoek, Roel Vermeulen, Mark Nieuwenhuijsen, Antonella Ficorilli, Bruna De Marchi, Annibale Biggeri, David Kocman, Johanna Amalia Robinson, Regina Grazuleviciene, Sandra Andrusaityte, Valeria Righi, Xavier Basagaña
Published in: Environment International, Issue 152, 2021, Page(s) 106470, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106470

Survey-derived activity space-based exposures to fast food outlets and their cross-sectional associations with use of fast food outlets, diet quality and BMI

Author(s): Mackenbach JD, Widener MJ, van der Gaag E, Pinho MGM
Published in: Health & Place, Issue Volume 79 / 2023, 2023, ISSN 1353-8292
Publisher: Elsevier BV
DOI: 10.1016/j.healthplace.2023.102966

Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England

Author(s): Whitaker M, Elliott J, Bodinier B, Barclay W, Ward H, Cooke G, Donnelly CA, Chadeau-Hyam M, Elliott P.
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-34244-2

Genotoxic effects of transboundary pollutants in Pinus mugo in the high mountain habitats

Author(s): Eva Klemmová Gregušková, Daniel Mihálik, Ján Kraic, Michaela Mrkvová, Jozef Sokol, Petr Gregor, Aneta Rafajová, Pavel Čupr,
Published in: Ecological Indicators, Issue Volume 140 / 2022, 2022, ISSN 1872-7034
Publisher: Elsevier
DOI: 10.1016/j.ecolind.2022.109009

Dynamics of competing SARS-CoV-2 variants during the Omicron epidemic in England.

Author(s): Eales O, de Oliveira Martins L, Page AJ, Wang H, Bodinier B, Tang D, Haw D, Jonnerby J, Atchison C, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Riley S, Elliott P, Donnelly CA, Chadeau-Hyam M.
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-32096-4

Hyperlocal variation of nitrogen dioxide, black carbon, and ultrafine particles measured with Google Street View cars in Amsterdam and Copenhagen

Author(s): Jules Kerckhoffs, Jibran Khan, Gerard Hoek, Zhendong Yuan, Ole Hertel, Matthias Ketzel, Steen Solvang Jensen, Fares Al Hasan, Kees Meliefste, Roel Vermeulen,
Published in: Environment International, Issue Volume 170 / 2022, 2022, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107575

The exposure of Czech firefighters to perfluoroalkyl substances and polycyclic aromatic hydrocarbons: CELSPAC – FIREexpo case-control human biomonitoring study

Author(s): Katarína Řiháčková, Aleš Pindur, Klára Komprdová, Nina Pálešová, Jiří Kohoutek, Petr Šenk, Jana Navrátilová, Lenka Andrýsková, Ludmila Šebejová, Richard Hůlek, Mazen Ismael, Pavel Čupr
Published in: Science of The Total Environment, Issue 881, 2024, Page(s) 163298, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.163298

Mixtures of long-term exposure to ambient air pollution, built environment and temperature and stroke incidence across Europe

Author(s): Jeroen de Bont; Regina Pickford; Christofer Åström; Fabian Coloma; Konstantina Dimakopoulou; Kees de Hoogh; Dorina Ibi; Klea Katsouyanni; Erik Melén; Federica Nobile; Göran Pershagen; Åsa Persson; Evangelia Samoli; Massimo Stafoggia; Cathryn Tonne; Jelle Vlaanderen; Kathrin Wolf; Roel Vermeulen; Annette Peters; Petter Ljungman
Published in: Environment International, Issue Volume 179, sept 2023, 2023, Page(s) 108136, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.108136

Automated calibration for stability selection in penalised regression and graphical models

Author(s): Barbara Bodinier; Sarah Filippi; Therese Haugdahl Nøst; Julien Chiquet; Marc Chadeau-Hyam
Published in: Bioinformatics, Issue Volume 39, Issue 11, Nov 2023, 2023, ISSN 0035-9254
Publisher: Blackwell Publishing Inc.
DOI: 10.1093/jrsssc/qlad058

Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study

Author(s): Gang Wang, Jenny Hallberg, Dimitrios Charalampopoulos, Maribel Casas Sanahuja, Robab Breyer-Kohansal, Arnulf Langhammer, Raquel Granell, Judith M. Vonk, Annemiek Mian, Núria Olvera, Lisbeth Mølgaard Laustsen, Eva Rönmark, Alicia Abellan, Alvar Agusti, Syed Hasan Arshad, Anna Bergström, H. Marike Boezen, Marie-Kathrin Breyer, Otto Burghuber, Anneli Clea Bolund, Adnan Custovic, Graham Devereux,
Published in: ERJ open research, Issue 7: 00457-2021, 2021, ISSN 2312-0541
Publisher: European Respiratory Society
DOI: 10.1183/23120541.00457-2021

Breakthrough SARS-CoV-2 infections in double and triple vaccinated adults and single dose vaccine effectiveness among children in Autumn 2021 in England: REACT-1 study

Author(s): Chadeau-Hyam M, Eales O, Bodinier B, Wang H, Haw D, Whitaker M, Elliott J, Walters CE, Jonnerby J, Atchison C, Diggle PJ, Page AJ, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Donnelly CA, Elliott P
Published in: EClinicalMedicine, 2022, ISSN 2589-5370
Publisher: Elsevier
DOI: 10.1016/j.eclinm.2022.101419

Persistent COVID-19 symptoms in a community study of 606,434 people in England

Author(s): Whitaker M, Elliott J, Chadeau-Hyam M, Riley S, Darzi A, Cooke G, Ward H, Elliott P
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-29521-z

Validating and constructing behavioral models for simulation andprojection using automated knowledge extraction

Author(s): Tabea S. Sonnenschein, G. Ardine de Wit, Nicolette R. den Braver, Roel C.H. Vermeulen, Simon Scheider
Published in: Information Sciences, Issue Volume 662, March 2024, 2024, Page(s) 120232, ISSN 1879-0283
Publisher: Elsevier
DOI: 10.1016/j.ins.2024.120232

Education, biological ageing, all-cause and cause-specific mortality and morbidity: UK biobank cohort study

Author(s): Marc Chadeau-Hyam, Barbara Bodinier, Roel Vermeulen, Maryam Karimi, Verena Zuber, Raphaële Castagné, Joshua Elliott, David Muller, Dusan Petrovic, Matthew Whitaker, Silvia Stringhini, Ioanna Tzoulaki, Mika Kivimäki, Paolo Vineis, Paul Elliott, Michelle Kelly-Irving, Cyrille Delpierre
Published in: EClinicalMedicine, Issue 29-30, 2020, Page(s) 100658, ISSN 2589-5370
Publisher: Elsevier
DOI: 10.1016/j.eclinm.2020.100658

Rapid increase in Omicron infections in England during December 2021: REACT-1 study.

Author(s): Elliott P, Bodinier B, Eales O, Wang H, Haw D, Elliott J, Whitaker M, Jonnerby J, Tang D, Walters CE, Atchison C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Ward H, Darzi A, Cooke GS, Chadeau-Hyam M, Donnelly CA.
Published in: Science, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abn8347

Exposure to ambient ultrafine particles and allergic sensitization in children up to 16 years

Author(s): Bouma, Femke; Hoek, Gerard; Koppelman, Gerard H; Vonk, Judith M; Kerckhoffs, Jules; Vermeulen, Roel; Gehring, Ulrike; IRAS OH Epidemiology Chemical Agents
Published in: Environmental Research, Issue 2023, 2023, ISSN 1096-0953
Publisher: Elsevier
DOI: 10.1289/isee.2022.p-0433

Current-use pesticide exposure pathways in Czech adults and children from the CELSPAC-SPECIMEn cohort

Author(s): Libor Šulc, Daniel Figueiredo, Anke Huss, Jiří Kalina, Petr Gregor, Tomáš Janoš, Petr Šenk, Andrea Dalecká, Lenka Andrýsková, Vít Kodeš, Pavel Čupr
Published in: Environment International, Issue 181, 2023, Page(s) 108297, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.108297

Analytical strategies for chemical exposomics: exploring limits and feasibility

Author(s): Chiara Maria Vitale, Elliott J Price, Gary W Miller, Arthur David, Jean-Philippe Antignac, Robert Barouki, Jana Klánová,
Published in: Exposome, Issue Volume 1 / 2021, 2021, ISSN 2635-2265
Publisher: Oxford University Press
DOI: 10.1093/exposome/osab003

Residential proximity to livestock animals and mortality from respiratory diseases in The Netherlands: A prospective census-based cohort study

Author(s): Mariana Simões, Nicole Janssen, Dick Heederik, Lidwien Smit, Roel Vermeulen, Anke Huss
Published in: Environment International, Issue Volume 161 / 2022, 2022, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107140

Omicron SARS-CoV-2 epidemic in England during February 2022: A series of cross-sectional community surveys

Author(s): Chadeau-Hyam M, Tang D, Eales O, Bodinier B, Wang H, Jonnerby J, Whitaker M, Elliott J, Haw D, Walters CE, Atchison C, Diggle PJ, Page AJ, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Donnelly CA, Elliott P.
Published in: Lancet Regional Health Europe, 2022, ISSN 2666-7762
Publisher: Elsevier
DOI: 10.1016/j.lanepe.2022.100462

Modelling nationwide spatial variation of ultrafine particles based on mobile monitoring

Author(s): Jules Kerckhoffs, Gerard Hoek, Ulrike Gehring, Roel Vermeulen
Published in: Environment International, Issue 154, 2021, Page(s) 106569, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106569

City-scale assessment of long-term air quality impacts on the respiratory and cardiovascular health

Author(s): Libor Šulc, Petr Gregor, Jirí Kalina, Ondrej Mikes, Tomás Janos and Pavel Cupr
Published in: Frontiers in Public Health, Issue Volume 10 / 2022, 2022, ISSN 2296-2565
Publisher: Lausanne Frontiers Media S.A
DOI: 10.3389/fpubh.2022.1006536

Development of historic monthly land use regression models of SO2, NOx and suspended particulate matter for birth cohort ELSPAC

Author(s): Mikeš, Ondřej; Sáňka, Ondřej; Rafajová, Aneta; Vlaanderen, Jelle; Chen, Jie; Hoek, Gerard; Klánová, Jana; Čupr, Pavel
Published in: Atmospheric Environment, Issue Volume 301, 15 May 2023, 2023, Page(s) 119688, ISSN 1873-2844
Publisher: Elsevier
DOI: 10.1016/j.atmosenv.2023.119688

Impact of long-term exposure to PM2.5 on peripheral blood gene expression pathways involved in cell signaling and immune response

Author(s): Jelle Vlaanderen, Roel Vermeulen, Matthew Whitaker, Marc Chadeau-Hyam, Jouke-Jan Hottenga, Eco de Geus, Gonneke Willemsen, Brenda W.J.H. Penninx, Rick Jansen, Dorret I. Boomsma,
Published in: Environment International, Issue Volume 168 / 2022, 2022, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107491

Air pollution, metabolites and respiratory health across the life-course

Author(s): Gruzieva O, Jeong A, He S, Yu Z, de Bont J, Pinho MGM, Eze IC, Kress S, Wheelock CE, Peters A, Vlaanderen J, de Hoogh K, Scalbert A, Chadeau-Hyam M, Vermeulen RCH, Gehring U, Probst-Hensch N, Melén E.
Published in: European respiratory review, Issue Volume 31 / 2022, 2022, ISSN 1600-0617
Publisher: European respiratory society
DOI: 10.1183/16000617.0038-2022

Countrywide analysis of heat- and cold-related mortality trends in the Czech Republic: growing inequalities under recent climate warming

Author(s): Tomáš Janoš, Joan Ballester, Pavel Čupr, Hicham Achebak
Published in: International Journal of Epidemiology, Issue 53, 2024, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyad141

COVID-19 mortality in the UK Biobank cohort: revisiting and evaluating risk factors

Author(s): Joshua Elliott, Barbara Bodinier, Matthew Whitaker, Cyrille Delpierre, Roel Vermeulen, Ioanna Tzoulaki, Paul Elliott, Marc Chadeau-Hyam
Published in: European Journal of Epidemiology, Issue 36/3, 2021, Page(s) 299-309, ISSN 0393-2990
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10654-021-00722-y

Assessing How Social Exposures Are Integrated in Exposome Research: A Scoping Review

Author(s): Neufcourt L, Castagné R, Mabile L, Khalatbari-Soltani S, Delpierre C, Kelly-Irving M
Published in: Environmental Health Perspectives, Issue Volume 130 / 2022, 2022, ISSN 0091-6765
Publisher: US Department of Health and Human Services
DOI: 10.1289/ehp11015

Firefighters and the liver: Exposure to PFAS and PAHs in relation to liver function and serum lipids (CELSPAC-FIREexpo study)

Author(s): Nina Pálešová, Léa Maitre, Nikos Stratakis, Katarína Řiháčková, Aleš Pindur, Jiří Kohoutek, Petr Šenk, Anna Bartošková Polcrová, Petr Gregor, Martine Vrijheid, Pavel Čupr
Published in: International Journal of Hygiene and Environmental Health, Issue 252, 2023, Page(s) 114215, ISSN 1438-4639
Publisher: Elsevier BV
DOI: 10.1016/j.ijheh.2023.114215

Integrating Large-Scale Stationary and Local Mobile Measurements to Estimate Hyperlocal Long-Term Air Pollution Using Transfer Learning Methods

Author(s): Zhendong Yuan; Jules Kerckhoffs; Youchen Shen; Kees de Hoogh; Gerard Hoek; Roel Vermeulen
Published in: Environmental Research, Issue Volume 228 1 July 2023, 2023, ISSN 1096-0953
Publisher: Elsevier
DOI: 10.2139/ssrn.4341575

The quality of OpenStreetMap food-related point-of-interest data for use in epidemiological research

Author(s): Maria Gabriela M. Pinho, Benjamin Flueckiger, Antonia Valentin, Maria-Iosifina Kasdagli, Kalliopi Kyriakou, Jeroen Lakerveld, Joreintje D. Mackenbach, Joline W.J. Beulens, Kees de Hoogh
Published in: Health & Place, Issue Volume 83, September 2023, 2023, Page(s) 103075, ISSN 1873-2054
Publisher: Elsevier
DOI: 10.1016/j.healthplace.2023.103075

Effect of residential relocation on environmental exposures in European cohorts: An exposome-wide approach

Author(s): Apolline Saucy, Ulrike Gehring, Sergio Olmos, Cyrille Delpierre, Jeroen de Bont, Olena Gruzieva, Kees de Hoogh, Anke Huss, Petter Ljungman, Erik Melen, Åsa Persson, Inka Pieterson, Marjan Tewis, Zhebin Yu, Roel Vermeulen, Jelle Vlaanderen, Cathryn Tonne
Published in: Environmental International, Issue 173 107849, 2023, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.107849

An annotation database for chemicals of emerging concern in exposome research

Author(s): Jeroen Meijer, Marja Lamoree, Timo Hamers, Jean-Philippe Antignac, Sébastien Hutinet, Laurent Debrauwer, Adrian Covaci, Carolin Huber, Martin Krauss, Douglas I. Walker, Emma L. Schymanski, Roel Vermeulen, Jelle Vlaanderen
Published in: Environment International, Issue 152, 2021, Page(s) 106511, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106511

Variability of the Human Serum Metabolome over 3 Months in the EXPOsOMICS Personal Exposure Monitoring Study

Author(s): Max J. Oosterwegel; Dorina Ibi; Lützen Portengen; Nicole Probst-Hensch; Sonia Tarallo; Alessio Naccarati; Medea Imboden; Ayoung Jeong; Nivonirina Robinot; Augustin Scalbert; Andre F. S. Amaral; Erik van Nunen; John Gulliver; Marc Chadeau-Hyam; Paolo Vineis; Roel Vermeulen; Pekka Keski-Rahkonen; Jelle Vlaanderen
Published in: Environmental science & technology, Issue Aug 29;57(34):2023, 2023, Page(s) 12752-12759, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.3c03233

Where do Dutch adults obtain their snack foods? Cross-sectional exploration of individuals’ interactions with the food environment

Author(s): Mackenbach JD, Hobbs M, Pinho MGM
Published in: Health & Place, Issue Volume 75 / 2022, 2022, ISSN 1353-8292
Publisher: Elsevier BV
DOI: 10.1016/j.healthplace.2022.102802

Prospective Identification of Elevated Circulating CDCP1 in Patients Years before Onset of Lung Cancer

Author(s): Sonia Dagnino, Barbara Bodinier, Florence Guida, Karl Smith-Byrne, Dusan Petrovic, Matthew D. Whitaker, Therese Haugdahl Nøst, Claudia Agnoli, Domenico Palli, Carlotta Sacerdote, Salvatore Panico, Rosario Tumino, Matthias B. Schulze, Mikael Johansson, Pekka Keski-Rahkonen, Augustin Scalbert, Paolo Vineis, Mattias Johansson, Torkjel M. Sandanger, Roel C.H. Vermeulen, Marc Chadeau-Hyam
Published in: Cancer Research, Issue 81/13, 2021, Page(s) 3738-3748, ISSN 0008-5472
Publisher: American Association for Cancer Research
DOI: 10.1158/0008-5472.can-20-3454

SARS-CoV-2 infection and vaccine effectiveness in England (REACT-1): a series of cross-sectional random community surveys.

Author(s): Chadeau-Hyam M, Wang H, Eales O, Haw D, Bodinier B, Whitaker M, Walters CE, Ainslie KEC, Atchison C, Fronterre C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Riley S, Donnelly CA, Elliott P
Published in: The Lancet Respiratory Medicine, 2022, ISSN 2213-2600
Publisher: Elsevier Limited
DOI: 10.1016/s2213-2600(21)00542-7

Risk factors for positive and negative COVID-19 tests: a cautious and in-depth analysis of UK biobank data

Author(s): Marc Chadeau-Hyam, Barbara Bodinier, Joshua Elliott, Matthew D Whitaker, Ioanna Tzoulaki, Roel Vermeulen, Michelle Kelly-Irving, Cyrille Delpierre, Paul Elliott
Published in: International Journal of Epidemiology, Issue 49/5, 2020, Page(s) 1454-1467, ISSN 0300-5771
Publisher: Oxford University Press
DOI: 10.1093/ije/dyaa134

SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2.

Author(s): Eales O, Page AJ, de Oliveira Martins L, Wang H, Bodinier B, Haw D, Jonnerby J, Atchison C, Consortium C-GU, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Riley S, Chadeau-Hyam M, Donnelly CA, Elliott P.
Published in: BMC infectious diseases, Issue Volume 22 / 2022, 2022, Page(s) 647, ISSN 1471-2334
Publisher: BioMed Central
DOI: 10.1186/s12879-022-07628-4

The exposome and health: Where chemistry meets biology

Author(s): Roel Vermeulen, Emma L. Schymanski, Albert-László Barabási, Gary W. Miller
Published in: Science, Issue 367/6476, 2020, Page(s) 392-396, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aay3164

Europe-wide air pollution modeling from 2000 to 2019 using geographically weighted regression

Author(s): Youchen Shen, Kees de Hoogh, Oliver Schmitz, Nicholas Clinton, Karin Tuxen-Bettman, Jørgen Brandt, Jesper H. Christensen, Lise M. Frohn, Camilla Geels, Derek Karssenberg, Roel Vermeulen, Gerard Hoek,
Published in: Environment International, Issue Volume 168 / 2022, 2022, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107485

Enabling the Nonhypothesis-Driven Approach: On Data Minimalization, Bias, and the Integration of Data Science in Medical Research and Practice

Author(s): C. W. Safarlou, M. van Smeden, R. Vermeulen, K. R. Jongsma
Published in: The American Journal of Bioethics, Issue volume 23, 2023 - Issue 9, 2023, Page(s) 72-76, ISSN 1536-0075
Publisher: Taylor and Francis online
DOI: 10.1080/15265161.2023.2237452

Scrutinizing Privacy in Multi-Omics Research: How to Provide Ethical Grounding for the Identification of Privacy-Relevant Data Properties

Author(s): C.W. Safarlou, A.L. Bredenoord, R. Vermeulen & K.R. Jongsma
Published in: The American Journal of Bioethics, Issue Volume 21, issue 12, 2021, Page(s) 73-75, ISSN 1526-5161
Publisher: MIT Press
DOI: 10.1080/15265161.2021.1991041

Invited Perspective: Inroads to Biology-Informed Exposomics

Author(s): Vermeulen R.
Published in: Environmental Health Perspectives, Issue Volume 130 / 2022, 2022, ISSN 1552-9924
Publisher: JSTorg
DOI: 10.1289/ehp12224

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