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Monitoring Protein-Ligand Interactions in Human Cells by Real-Time Quantitative In-Cell NMR using a High Cell Density Bioreactor

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Characterization of a glycoside hydrolase endolysin from Acinetobacter baumannii phage AbTZA1 with high antibacterial potency and novel structural features

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New restraints and validation approaches for nucleic acid structures in PDB-REDO

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Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop

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Studies of proline conformational dynamics in IDPs by 13C-detected cross-correlated NMR relaxation

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A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline

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The Intriguing mitoNEET: Functional and Spectroscopic Properties of a Unique [2Fe-2S] Cluster Coordination Geometry

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Determinants of receptor tyrosine phosphatase homophilic adhesion: structural comparison of PTPRK and PTPRM extracellular domains

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Fixed Target Serial Data Collection at Diamond Light Source

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Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain

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Structural plasticity of NFU1 upon interaction with binding partners: insights into the mitochondrial [4Fe-4S] cluster pathway

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Evaluation of the Higher Order Structure of Biotherapeutics Embedded in Hydrogels for Bioprinting and Drug Release

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Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF

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High-Resolution Studies of Proteins in Natural Membranes by Solid-State NMR

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Experiences From Developing Software for Large X-Ray Crystallography-Driven Protein-Ligand Studies.

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In-cell NMR: Why and how?

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1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein)

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Intrinsically disordered plant protein PARCL co-localizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD

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Dissociation of β2m from MHC class I triggers formation of noncovalent transient heavy chain dimers

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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies

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Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity

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Progression of herpesvirus infection remodels mitochondrial organization and metabolism

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Phase distortion-free paramagnetic NMR spectra

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Disentangling Chromophore States in a Reversibly Switchable Green Fluorescent Protein: Mechanistic Insights from NMR Spectroscopy

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Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 2 Caused by CYS59TYR BOLA3 Mutation

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The folding landscapes of human telomeric RNA and DNA Gquadruplexesare markedly different

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Cost-Effective Protein Production in CHO Cells Following Polyethylenimine-Mediated Gene Delivery Showcased by the Production and Crystallization of Antibody Fabs

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Intracellular Binding/Unbinding Kinetics of Approved Drugs toCarbonic Anhydrase II Observed by in-Cell NMR

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Structural studies of β-glucosidase from the thermophilic bacterium <i>Caldicellulosiruptor saccharolyticus</i>

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Controlling the incorporation of fluorinated amino acids in human cells and its structural impact

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Exploring the druggability of conserved RNA regulatory elements in the SARS‐CoV‐2 genome

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Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action

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Cryo-EM density maps adjustment for subtraction, consensus and sharpening

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The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells.

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Cryo-focused ion beam lamella preparation protocol for in situ Structural Biology

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Image Processing in Cryo-Electron Microscopy of Single Particles: The Power of Combining Methods

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Mixed-valence compounds as polarizing agents for Overhauser dynamic nuclear polarization in solids

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Combining scattering experiments and colloid theory to characterize charge effects in concentrated antibody solutions

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Structural analysis of human ex vivo amyloid fibrils from systemic AA amyloidosis

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