Structural basis of controlling the membrane attack complex

Project Information

Controlling MAC

Grant agreement ID: 864751

DOI 10.3030/864751

EC signature date 31 January 2020

Start date 1 July 2020

End date 30 June 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 999 990,00

EU contribution € 1 999 990,00

Coordinated by

IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom

Publications

Peer reviewed articles (3)

Structural basis of soluble membrane attack complex packaging for clearance

Author(s): Anaïs Menny, Marie V Lukassen, Emma C Couves, Vojtech Franc, Albert J R Heck, Doryen Bubeck
Published in: Nature Communications, Issue Oct 19;12(1):6086, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-26366-w

Soluble Membrane Attack Complex: Biochemistry and Immunobiology

Author(s): Scott R Barnum, Doryen Bubeck, Theresa N Schein
Published in: Frontiers in Immunology, Issue 11:585108, 2020, ISSN 1664-3224
Publisher: Frontiers in Immunology
DOI: 10.3389/fimmu.2020.585108

Capturing pore-forming intermediates of MACPF and binary toxin assemblies by cryoEM

Author(s): Emma C Couves, Doryen Bubeck
Published in: Current Opinion in Structural Biology, Issue June 11; 75:102401, 2022, ISSN 0959-440X
Publisher: Elsevier BV
DOI: 10.1016/j.sbi.2022.102401