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Co-diversification and co-evolution of human populations and cereals in Africa

Descrizione del progetto

Alla scoperta del rapporto coevolutivo tra i cereali e le popolazioni umane

La genetica delle migrazioni umane e quella della domesticazione delle piante sono intrecciate l’una con l’altra. Tuttavia, vengono trattate separatamente nella ricerca. Il progetto CODEV, finanziato dall’UE, studierà l’interazione di questi processi in Africa utilizzando un approccio multidisciplinare che si concentra sui dati genomici umani e vegetali. Il progetto si propone di chiarire se le popolazioni cerealicole e umane si siano effettivamente coevolute e coadattate, oltre a fornire valutazioni sulle dinamiche neutre e adattive legate alla transizione agricola. Il lavoro del progetto stimolerà la ricerca sull’Africa e sulle risorse biologiche africane.

Obiettivo

The Neolithic agricultural revolution is a key step in recent human evolution that dramatically shaped genetic diversity and adaptations of today populations. Plant domestication played a crucial role in its set-up. Yet the genetics of human migrations and plant domestication is addressed separately. CODEV explores the interaction between these processes in Africa, with an innovative multidisciplinary approach that jointly analyses human and plant genomic data, complemented by ethno-linguistic and environmental information. The largest genomic data-sets available to date of three mayor African cereals and human populations will be analyzed to identify congruent and idiosyncratic signatures of spatio-temporal evolutionary processes. CODEV will inform about whether cereal and human populations have undergone parallel or convergent evolution and co-adaptation.
CODEV will yield novel evolutionary insights on the neutral and adaptive dynamics associated with the agricultural transition, a topic of great scientific and public interest. CODEV will also contribute to strengthening research on Africa and African biological resources, still poorly characterized. Determining the genetic bases of adaptation to agriculture is relevant to understand farming-related human diseases. The identification of adaptive genes in cereals informs crop improvement towards more sustainable and hazard-resilient varieties. Transfer of knowledge and capacity building activities will be addressed to European and African graduate students and researchers and outreach events will allow sharing CODEV findings with the civil society.
This MSC action will increase the researcher competitiveness for career consolidation through new knowledge on human evolutionary genetics and species interaction analysis, and the increase of her international network. The specialized training enabled by CODEV will reinforce her skills in leadership and project management, scientific dissemination and mentoring.

Meccanismo di finanziamento

MSCA-IF-EF-ST - Standard EF

Coordinatore

UPPSALA UNIVERSITET
Contribution nette de l'UE
€ 203 852,16
Indirizzo
VON KRAEMERS ALLE 4
751 05 Uppsala
Svezia

Mostra sulla mappa

Regione
Östra Sverige Östra Mellansverige Uppsala län
Tipo di attività
Higher or Secondary Education Establishments
Collegamenti
Costo totale
€ 203 852,16