Induced pluripotent stem cell seeded active osteochondral nanofibrous scaffolds

Project Information

iP-OSTEO

Grant agreement ID: 824007

DOI 10.3030/824007

Project closed

EC signature date 14 November 2018

Start date 1 February 2019

End date 31 July 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 1 099 400,00

EU contribution € 1 099 400,00

Coordinated by

USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
Czechia

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (1)

Project website

Website about iP-OSTEO activities.

Open Research Data Pilot (1)

Data Management Plan (DMP

Data management plan for ORDP pilot.

Publications

Peer reviewed articles (15)

Smart Electrospun Hybrid Nanofibers Functionalized with Ligand-Free Titanium Nitride (TiN) Nanoparticles for Tissue Engineering

Author(s): Viraj P. Nirwan, Eva Filova, Ahmed Al-Kattan, Andrei V. Kabashin, Amir Fahmi
Published in: Nanomaterials, Issue 11/2, 2021, Page(s) 519, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano11020519

A simple route to functionalising electrospun polymer scaffolds with surface biomolecules

Author(s): Dziemidowicz, K; Brocchini, S; Williams, GR
Published in: International Journal of Pharmaceuticals, Issue 597, 2021, Page(s) 120231, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2021.120231

Protein encapsulation by electrospinning and electrospraying

Author(s): Anabela Moreira, Dan Lawson, Lesley Onyekuru, Karolina Dziemidowicz, Ukrit Angkawinitwong, Pedro F. Costa, Norbert Radacsi, Gareth R. Williams
Published in: Journal of Controlled Release, Issue 329, 2021, Page(s) 1172-1197, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2020.10.046

Electrosprayed Particles Loaded with Kartogenin as a Potential Osteochondral Repair Implant

Author(s): Sebastian J. Gurgul, Anabela Moreira, Yi Xiao, Swastina Nath Warma, Chaozong Liu, pedro F. Costa, Gareth R. Williams
Published in: Polymers, Issue 15 (5), 2023, Page(s) 1275, ISSN 2073-4360
Publisher: MDPI
DOI: 10.3390/polym15051275

Water-Insoluble, Thermostable, Crosslinked Gelatin Matrix for Soft Tissue Implant Development

Author(s): Viktória Varga, László Smeller, Róbert Várdai, Bence Kocsis, Ibolya Zsoldos, Sara Cruciani, Renzo Pala, István Hornyák
Published in: International Journal of Molecular Sciences, Issue 25, 2025, Page(s) 4336, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms25084336

An investigation of alkaline phosphatase enzymatic activity after electrospinning and electrospraying

Author(s): Lesley C. Onyekuru, Anabela Moreira, Jiazhe Zhang, Ukrit Angkawinitwong, Pedro F. Costa, Steve Brocchini, Gareth R. Williams
Published in: Journal of Drug Delivery Science and Technology, Issue 64, 2021, Page(s) 102592, ISSN 2588-8943
Publisher: Elsevier
DOI: 10.1016/j.jddst.2021.102592

Xeno-Hybrid Bone Graft Releasing Biomimetic Proteins Promotes Osteogenic Differentiation of hMSCs

Author(s): Hao Zhu, Veronika Hefka Blahnová, Giuseppe Perale, Jun Xiao, Felice Betge, Fabio Boniolo, Eva Filová, Ståle Petter Lyngstadaas, Håvard Jostein Haugen
Published in: Frontiers in Cell and Developmental Biology, Issue 8, 2020, ISSN 2296-634X
Publisher: Frontiers
DOI: 10.3389/fcell.2020.619111

Bio-inspired nanoporous scaffold: electrospun hybrid fibers based on self-assembled block copolymer mineralized with inorganic nanoparticles for bone tissue engineering

Author(s): Leal, Filipa); Nirwan, Viraj; Gonçalves, Andreia M.; Panitschewski, Nikolai; Filová, Eva; Fahmi, Amir; Costa, Pedro F.
Published in: INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, Issue 73(12), 2023, Page(s) 1054-1067, ISSN 1563-535X
Publisher: TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2023.2243369

Advances in Electrospun Hybrid Nanofibers for Biomedical Applications

Author(s): Nirwan, Viraj P; Kowalczyk, Tomasz; Bar, J; Buzgo, Matej; Filová, Eva; Fahmi, Amir
Published in: Nanomaterials, Issue 12 (11), 2022, Page(s) Article number 1829, ISSN 2079-4991
Publisher: MDPI
DOI: 10.3390/nano12111829

Electrospun Antimicrobial Drug Delivery Systems and Hydrogels Used for Wound Dressings

Author(s): Zahra Moazzami Goudarzi, Angelika Zaszczyńska, Tomasz Kowalczyk, Paweł Sajkiewicz
Published in: Pharmaceutics, Issue 16, 2024, Page(s) 93, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics16010093

Cellular Responce to Individual Components of the Platelet Concentrate

Author(s): Vera Sovkova, Karolina Vocetkova, Věra Hedvičáková, Veronika Hefka Blahnová, Matěj Buzgo, Evzen Amler, Eva Filová
Published in: International Jpurnal of Molecular Sciences, Issue 22(9), 2021, Page(s) 4539, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22094539

Osteochondral Tissue Engineering: The Potential of Electrospinning and Additive Manufacturing

Author(s): Andreia M. Gonçalves, Anabela Moreira, Achim Weber, Gareth R. Williams, Pedro F. Costa
Published in: Pharmaceutics, Issue 13(7), 2021, Page(s) 983, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13070983

Piezoelectric Scaffolds as Smart Materials for Bone Tissue Engineering

Author(s): Angelika Zaszczyńska, Konrad Zabielski, Arkadiusz Gradys, Tomasz Kowalczyk, Paweł Sajkiewicz
Published in: Polymers, Issue 16, 2024, Page(s) 2797, ISSN 2073-4360
Publisher: mdpi
DOI: 10.3390/polym16192797

Osteogenic Potential of Human Dental Pulp Stem Cells (hDPSCs) Growing on Poly L-Lactide-Co-Caprolactone and Hyaluronic Acid (HYAFF-11TM) Scaffolds

Author(s): Julia K. Bar, Anna Lis-Nawara, Tomasz Kowalczyk, Piotr G. Grelewski, Sandra Stamnitz, Hanna Gerber, Aleksandra Klimczak
Published in: International Journal of Molecular Sciences, Issue 24, 2023, Page(s) 16747, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms242316747

The Gradual Release of Alendronate for the Treatment of Critical Bone Defects in Osteoporotic and Control Rats

Author(s): Hedvičáková V, Žižková R, Buzgo M, Vištejnová L, Klein P, Hovořáková M, Bartoš M, Steklíková K, Luňáčková J, Šebová E, Paurová I, Rysová M, Filová E, Rampichová M
Published in: International journal of nanomedicine, Issue 18, 2023, Page(s) 541-560, ISSN 1178-2013
Publisher: Dove medical press Ltd
DOI: 10.2147/ijn.s386784

Conference proceedings (3)

High-throughput electrospinning of bioactive scaffolds for bone regeneration

Author(s): Herman Novik, Marta Clerici, Amir Fahmi, Matej Buzgo, Aiva Simaite
Published in: Proceedings of The 1st International Electronic Conference on Pharmaceutics, 2020, Page(s) 8666
Publisher: MDPI
DOI: 10.3390/iecp2020-08666

Optimization of the emulsion electrospinning for increased activity of biopharmaceuticals

Author(s): Natalia Burlaga, Magdalena Bartolewska, Matej Buzgo, Aiva Simaite
Published in: Proceedings of The 1st International Electronic Conference on Pharmaceutics, 2020, Page(s) 8673
Publisher: MDPI
DOI: 10.3390/iecp2020-08673

Pitfalls of accurate protein determination inside PLGA nanoparticles using the microBCA assay

Author(s): Marta Clerici, Levi Nelemans, Aiva Simaite, Matej Buzgo
Published in: Proceedings of The 1st International Electronic Conference on Pharmaceutics, 2020, Page(s) 8671
Publisher: MDPI
DOI: 10.3390/iecp2020-08671