Project description
Effectively assessing the risks of nanomaterials
The health, safety and environmental management of nanomaterials (NMs) is increasingly important. Currently, there is no complete understanding of NMs' impacts, and emerging NMs require new risk management approaches. The EU-funded NanoSolveIT project will introduce a ground-breaking in silico Integrated Approach to Testing and Assessment (IATA) for NMs, implemented as a decision support system presented via stand-alone open software and a cloud platform. The project will develop a knowledge-based infrastructure for data hosting, sharing and exploitation via predictive modelling, to support NM grouping and risk assessment using nanodescriptors that are predictively linked to NM functionality, exposure and hazard. Project outcomes will benefit stakeholders at each stage of the NM value chain.
Objective
NanoSolveIT will introduce a ground-breaking in silico Integrated Approach to Testing and Assessment (IATA) for the environmental health and safety of Nanomaterials (NM), implemented as a decision support system packaged as a standalone open software and a Cloud platform. NanoSolveIT will develop and deliver: (i) a reliable user friendly knowledge-based infrastructure for data hosting, sharing and exploitation, (ii) NM fingerprints, sets of nanodescriptors and properties that can be predictively linked to NM functionality, exposure and hazard, thereby supporting NM grouping, safe-by-design (SbD) and regulatory risk assessment (RA), (iii) innovative methodologies for NMs predictive (eco)toxicology underpinned by artificial intelligence and state-of-the-art in silico techniques, and, (iv) integration with multi-scale modelling, RA and governance frameworks developed in EU H2020 funded and in the forthcoming NMBP-13 project(s). NanoSolveIT will deliver a validated, sustainable, multi-scale nanoinformatics IATA, tested and demonstrated at TLR6 via OECD style IATA case studies, serving the needs of diverse stakeholders at each stage of the NMs value chain, for assessment of potential adverse effects of NM on human health and the environment. NanoSolveIT is fully aligned to the objectives of the EU-US Nanoinformactics Roadmap, addressing all 13 of its short, medium and long term milestones, and supports the recommendations of the EMMC on standards for developing material modelling software and OECD best practice. The NanoSolveIT consortium (EU and international partners) is the only grouping capable of delivering the ambitious goals of the NMBP-14-2018 call, since they have collectively driven most of the current progress in nanoinformatics: 81% of the nanoinormatics papers cited in the EU-US nanoinformatics roadmap had NanoSolveIT authors. NanoSolveIT will integrate across the consortium-wide modelling approaches to provide the IATA platform for in silico NMs RA.
Fields of science
Keywords
Programme(s)
Funding Scheme
RIA - Research and Innovation actionCoordinator
1070 Nicosia
Cyprus
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
Participants (27)
Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
PIRAEUS
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B15 2TT Birmingham
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157 80 ATHINA
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4 Dublin
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33100 Tampere
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20520 Turku
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
6200 MD Maastricht
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80-172 Gdansk
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
10691 Stockholm
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2100 Kobenhavn
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Participation ended
37073 Gottingen
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Participation ended
SN2 1FL Swindon
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82152 STEINKIRCHEN
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
51005 Tartu
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2027 Kjeller
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12205 Berlin
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27599 Chapel Hill
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94607 OAKLAND CA
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39217-0095 Jackson
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27708 Durham Nc
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3086 La Trobe University
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305 8506 Tsukuba
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133-791 SEOUL
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2131 Sandringham
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305-340 DAEJEON
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06611 SOEUL
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
OX10 8BB Oxford
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