Genetics of Individuality

Informazioni relative al progetto

IndiGene

ID dell’accordo di sovvenzione: 810172

DOI 10.3030/810172

Data della firma CE 18 Gennaio 2019

Data di avvio 1 Febbraio 2019

Data di completamento 31 Luglio 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 6 272 613,00

Contributo UE € 6 272 613,00

Coordinato da

EUROPEAN MOLECULAR BIOLOGY LABORATORY
Germany

Risultati finali

Open Research Data Pilot (1)

Data Management Plan

Data Management Plan for the Open Research Data Pilot

Pubblicazioni

Peer reviewed articles (8)

Genomic variations and epigenomic landscape of the Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel

Autori: Adrien Leger, Ian Brettell, Jack Monahan, Carl Barton, Nadeshda Wolf, Natalja Kusminski, Cathrin Herder, Narendar Aadepu, Clara Becker, Jakob Gierten, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Tinatini Tavhelidse, Thomas Thumberger, Erika Tsingos, Philip Watson, Bettina Welz, Kiyoshi Naruse, Felix Loosli, Joachim Wittbrodt, Ewan Birney & Tomas Fitzg
Pubblicato in: Genome Biology, Numero 23, Article number: 58, 2022, ISSN 1474-760X
Editore: Springer Nature
DOI: 10.1186/s13059-022-02602-4

Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development

Autori: Lucie Zilova, Venera Weinhardt, Tinatini Tavhelidse, Christina Schlagheck, Thomas Thumberger, Joachim Wittbrodt
Pubblicato in: eLife, Numero 10, 2021, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.66998

Boosting targeted genome editing using the hei-tag

Autori: Thomas ThumbergerTinatini Tavhelidse-SuckJose Arturo Gutierrez-TrianaAlex CorneanRebekka MedertBettina WelzMarc FreichelJoachim Wittbrodt
Pubblicato in: eLife, 2022, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.70558

The Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel

Autori: Tomas Fitzgerald, Ian Brettell, Adrien Leger, Nadeshda Wolf, Natalja Kusminski, Jack Monahan, Carl Barton, Cathrin Herder, Narendar Aadepu, Jakob Gierten, Clara Becker, Omar T. Hammouda, Eva Hasel, Colin Lischik, Katharina Lust, Natalia Sokolova, Risa Suzuki, Erika Tsingos, Tinatini Tavhelidse, Thomas Thumberger, Philip Watson, Bettina Welz, Nadia Khouja, Kiyoshi Naruse, Ewan Birney, Joachim Wittb
Pubblicato in: Genome Biology, Numero 23, Article number: 59, 2022, ISSN 1474-760X
Editore: Springer Nature
DOI: 10.1186/s13059-022-02623-z

Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions

Autori: Jakob Gierten, Christian Pylatiuk, Omar T. Hammouda, Christian Schock, Johannes Stegmaier, Joachim Wittbrodt, Jochen Gehrig, Felix Loosli
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-58563-w

De novo PAM generation to reach initially inaccessible target sites for base editing

Autori: Kaisa Pakari, Joachim Wittbrodt, Joachim Wittbrodt
Pubblicato in: Development, 2023, ISSN 0950-1991
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dev.201115

CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease

Autori: Lino Doering, Alex Cornean, Thomas Thumberger, Joergen Benjaminsen, Beate Wittbrodt, Tanja Kellner, Omar T. Hammouda, Matthias Gorenflo, Joachim Wittbrodt and Jakob Gierten
Pubblicato in: | Disease Models & Mechanisms, 2023, ISSN 1754-8403
Editore: The Company of Biologists Ltd.
DOI: 10.1242/dmm.049811

Precise in vivo functional analysis of DNA variants with base editing using ACEofBASEs target prediction

Autori: Alex Cornean, Jakob Gierten, Bettina Welz, Juan Luis Mateo, Thomas Thumberger, Joachim Wittbrodt
Pubblicato in: eLife, 2022, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.72124