Point-of-care device based on KETs for diagnosis of food allergies

Livrables

Last version of the dissemination plan

This second version will encompass how the design of the clinical trial will be in order to gather solid evidence against current gold standard and the assessment related to the performance of the AlleScreening device

Health Technology Assessment v1

This is the first version of the Health Technology Assessment. It defines the criteria that a device for detecting allergies in the PoC should meet to be cost-effective against current clinical practice.

Handbook on management

The Management handbook summarises all the required knowledge for the good management of the project (in terms of administrative forms, financial aspects, quality process…).

Initial dissemination plan

The dissemination plan encompasses the publications to be developed, the target groups to aim at and the platforms to use to make known the project and its results.

Updated dissemination report

This is an updated version of the dissemination plan.

Dissemination material (Project e-newsletters and brochures).

Dissemination materials such as newsletters and brochures.

Project public website

This is a the project website to make known the project. It will also be a tool to manage the internal documents related to the project among its partners.

Publications

New applications of advanced instrumental techniques for the characterization of food allergenic proteins

Auteurs: Benedé S, Lozano-Ojalvo D, Cristobal S, Costa J, D'Auria E, Velickovic TC, Garrido-Arandia M, Karakaya S, Mafra I, Mazzucchelli G, Picariello G, Romero-Sahagun A, Villa C, Roncada P, Molina E.
Publié dans: Critical Reviews in Food Science and Nutrition, 2021, ISSN 1040-8398
Éditeur: Taylor & Francis
DOI: 10.1080/10408398.2021.1931806

Real-life evaluation of molecular multiplex IgE test methods in the diagnosis of pollen associated food allergy

Auteurs: Diem L., Neuherz B., Rohrhofer J., Koidl L., Asero R., Brockow K., Diaz-Perales A., Faber A., Gebhardt J., Torres MJ., Jensen-Jarolim E., Zehetmayer S., Untersmayr E.
Publié dans: Allergy, 2022, ISSN 1398-9995
Éditeur: John Wiley and Sons
DOI: 10.1111/all.15329

NLRP3 priming due to skin damage precedes LTP allergic sensitization in a mouse model

Auteurs: Diego Pazos-Castro, Zulema González-Klein, Alma Yuste-Montalvo, Guadalupe Hernández-Ramírez, Alejandro Romero-Sahagún, Vanesa Esteban, María Garrido-Arandia, Jaime Tome-Amat, Araceli Díaz-Perales
Publié dans: Scientific Reports, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-07421-y

The uncertainty and limit of detection in biosensors from immunoassays

Auteurs: Jesús de Vicente, Álvaro Lavín, Miguel Holgado, María F Laguna, Rafael Casquel, Beatriz Santamaría, Sergio Quintero, Ana L Hernández, Yolanda Ramírez
Publié dans: Measurement Science and Technology, Numéro 31/4, 2020, Page(s) 044004, ISSN 0957-0233
Éditeur: Institute of Physics and the Physical Society
DOI: 10.1088/1361-6501/ab49ec

New Label-Free Biosensing for the Evaluation of the AX-024 Inhibitor: Case Study for the Development of New Drugs in Autoimmune Diseases

Auteurs: Yolanda Ramírez, María Fe Laguna and Miguel Holgado
Publié dans: Sensors, 2022, ISSN 1424-8220
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s22031218

Developing an Optical Interferometric Detection Method based biosensor for detecting specific SARS-CoV-2 immunoglobulins in Serum and Saliva, and their corresponding ELISA correlation.

Auteurs: A.M.M. Murillo; Jaime Tome-Amat; Yolanda Ramírez; María Garrido-Arandia; L.G. Valle; L.G. Valle; Guadalupe Hernandez-Ramirez; L. Tramarin; L. Tramarin; Pedro Herreros; Pedro Herreros; Beatriz Santamaría; Beatriz Santamaría; Araceli Díaz-Perales; Araceli Díaz-Perales; Miguel Holgado; Miguel Holgado
Publié dans: Sensors and Actuators. B, Chemical, Numéro 4, 2021, ISSN 0925-4005
Éditeur: Elsevier BV
DOI: 10.1016/j.snb.2021.130394

ImmunoCAP ISAC in food allergy diagnosis: a systematic review of diagnostic test accuracy

Auteurs: José-María Maesa, Agnieszka Dobrzynska, Elena Baños-Álvarez, Rebeca Isabel-Gómez, Juan-Antonio Blasco-Amaro
Publié dans: Clinical and experimental allergy, 2021, ISSN 1365-2222
Éditeur: John Wiley & Sons Ltd
DOI: 10.1111/cea.13871

A new optical interferometric-based in vitro detection system for the specific IgE detection in serum of the main peach allergen

Auteurs: R.L. Espinosa, M. Garrido-Arandia, A. Romero-Sahagun, P. Herreros, L. Tramarin, M.F. Laguna, A. Díaz-Perales, M. Holgado
Publié dans: Biosensors and Bioelectronics, Numéro 169, 2020, Page(s) 112641, ISSN 0956-5663
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2020.112641

A Comparative Study of Human Saposins

Auteurs: María Garrido-Arandia, Bruno Cuevas-Zuviría, Araceli Díaz-Perales, Luis Pacios
Publié dans: Molecules, Numéro 23/2, 2018, Page(s) 422, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules23020422

Energy Landscapes of Ligand Motion Inside the Tunnel-Like Cavity of Lipid Transfer Proteins: The Case of the Pru p 3 Allergen

Auteurs: Bruno Cuevas-Zuviría, María Garrido-Arandia, Araceli Díaz-Perales, Luis Pacios
Publié dans: International Journal of Molecular Sciences, Numéro 20/6, 2019, Page(s) 1432, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20061432

Interaction of Alt a 1 with SLC22A17 in the airway mucosa

Auteurs: María Garrido‐Arandia, Jaime Tome‐Amat, Diego Pazos‐Castro, Vanesa Esteban, Maria M. Escribese, Guadalupe Hernández‐Ramírez, Alma Yuste‐Montalvo, Domingo Barber, Luis F. Pacios, Araceli Díaz‐Perales
Publié dans: Allergy, 2019, ISSN 0105-4538
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/all.13877

Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model

Auteurs: Maria J. Rodriguez, Javier Ramos-Soriano, James R. Perkins, Ainhoa Mascaraque, Maria J. Torres, Francisca Gomez, Araceli Diaz-Perales, Javier Rojo, Cristobalina Mayorga
Publié dans: Scientific Reports, Numéro 9/1, 2019, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-019-40114-7

On the Determination of Uncertainty and Limit of Detection in Label-Free Biosensors

Auteurs: Álvaro Lavín, Jesús Vicente, Miguel Holgado, María Laguna, Rafael Casquel, Beatriz Santamaría, María Maigler, Ana Hernández, Yolanda Ramírez
Publié dans: Sensors, Numéro 18/7, 2018, Page(s) 2038, ISSN 1424-8220
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s18072038

A Proof-of-Concept of Label-Free Biosensing System for Food Allergy Diagnostics in Biophotonic Sensing Cells: Performance Comparison with ImmunoCAP

Auteurs: Rocio Espinosa, María Laguna, Fátima Fernández, Beatriz Santamaria, Francisco Sanza, Maria Maigler, Juan Álvarez-Millán, Víctor Canalejas-Tejero, Miguel Holgado
Publié dans: Sensors, Numéro 18/8, 2018, Page(s) 2686, ISSN 1424-8220
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s18082686

A New Device Based on Interferometric Optical Detection Method for Label-Free Screening of C-Reactive Protein

Auteurs: Maria V. Maigler, Miguel Holgado, Maria Fe Laguna, Francisco J. Sanza, Beatriz Santamaria, Alvaro Lavin, Rocio L. Espinosa
Publié dans: IEEE Transactions on Instrumentation and Measurement, 2018, Page(s) 1-7, ISSN 0018-9456
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tim.2018.2876073

Performance of basophil activation test and specific IgG4 as diagnostic tools in nonspecific lipid transfer protein allergy: Antwerp‐Barcelona comparison

Auteurs: Ine I. Decuyper, Mariona Pascal, Athina L. Van Gasse, Christel Mertens, Araceli Díaz‐Perales, Giovanna Araujo, Maria Torradeflot, Josefina Rius, Sara Balsells, Rosa M. Muñoz‐Cano, Joan Bartra, Lynne Li, Vito Sabato, Margo M. Hagendorens, Chris H. Bridts, Luc S. De Clerck, Didier G. Ebo, Margaretha A. Faber
Publié dans: Allergy, Numéro 75/3, 2020, Page(s) 616-624, ISSN 0105-4538
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/all.14040

A Point-of-Care Based on Label-Free Interferometric Optical Detection Method to Evaluate Interferon Gamma (IFN-γ): A Correlation with the ELISA Technique

Auteurs: María Fe Laguna Heras, Yolanda Ramirez, Celia Fernández Martín, Rocío L. Espinosa, Alvaro Lavín, Miguel Holgado
Publié dans: Sensors, Numéro 20/17, 2020, Page(s) 4776, ISSN 1424-8220
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s20174776

The key to the allergenicity of lipid transfer protein (LTP) ligands: A structural characterization

Auteurs: Zulema Gonzalez-Klein, Bruno Cuevas-Zuviria, Andrea Wangorsch, Guadalupe Hernandez-Ramirez, Diego Pazos-Castro, Carmen Oeo-Santos, Alejandro Romero-Sahagun, Luis F. Pacios, Jaime Tome-Amat, Stephan Scheurer, Araceli Diaz-Perales, María Garrido-Arandia
Publié dans: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Numéro 1866/7, 2021, Page(s) 158928, ISSN 1388-1981
Éditeur: Elsevier BV
DOI: 10.1016/j.bbalip.2021.158928

Optical Vapor Sensors Based on Periodic Resonant Nanopillar Structures

Auteurs: Sergio Quintero, Rafael Casquel, Maria Fe Laguna, Miguel Holgado
Publié dans: ACS Omega, Numéro 5/40, 2020, Page(s) 25913-25918, ISSN 2470-1343
Éditeur: ACS Omega
DOI: 10.1021/acsomega.0c03279

Droits de propriété intellectuelle

OPTICAL METHOD OF DETECTION OF A TARGETED MOLECULE THROUGH AMPLIFICATION IN THE RESPONSE OF INTERFERENCE BY INDEX OF REFRACTION AND DISPERSION (Machine-translation by Google Translate, not legally binding)

Numéro de demande/publication: 20 1931066
Date: 2019-12-02
Demandeur(s): BIO OPTICAL DETECTION SL

OPTICAL METHOD OF DETECTION OF A TARGETED MOLECULE THROUGH AMPLIFICATION IN THE RESPONSE OF INTERFERENCE BY INDEX OF REFRACTION AND DISPERSION (Machine-translation by Google Translate, not legally binding)

Numéro de demande/publication: 20 1931066
Date: 2019-12-02
Demandeur(s): UNIVERSIDAD POLITECNICA DE MADRID

OPTICAL METHOD OF DETECTION OF A TARGETED MOLECULE THROUGH AMPLIFICATION IN THE RESPONSE OF INTERFERENCE BY INDEX OF REFRACTION AND DISPERSION (Machine-translation by Google Translate, not legally binding)

Numéro de demande/publication: 20 1931066
Date: 2019-12-02
Demandeur(s): BIO OPTICAL DETECTION SL

OPTICAL METHOD OF DETECTION OF A TARGETED MOLECULE THROUGH AMPLIFICATION IN THE RESPONSE OF INTERFERENCE BY INDEX OF REFRACTION AND DISPERSION (Machine-translation by Google Translate, not legally binding)

Numéro de demande/publication: 20 1931066
Date: 2019-12-02
Demandeur(s): UNIVERSIDAD POLITECNICA DE MADRID

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Publications

Droits de propriété intellectuelle

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