Restoring natural feelings from missing or damaged peripheral nervous system by model-driven neuroprosthesis

Project Information

FeelAgain

Grant agreement ID: 759998

DOI 10.3030/759998

Project closed

EC signature date 26 January 2018

Start date 1 April 2018

End date 31 March 2024

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 499 637,00

EU contribution € 1 499 637,00

Coordinated by

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

Publications

Peer reviewed articles (25)

Recalibration of neuromodulation parameters in neural implants with adaptive Bayesian optimization

Author(s): Giovanna Aiello, Giacomo Valle, Stanisa Raspopovic
Published in: Journal of Neural Engineering, Issue 20, 2023, Page(s) 026037, ISSN 1741-2560
Publisher: Institute of Physics Publishing
DOI: 10.1088/1741-2552/acc975

Multisensory stimulation decreases phantom limb distortions and is optimally integrated

Author(s): Gaia Risso; Greta Preatoni; Giacomo Valle; Michele Marazzi; Noëlle Moana Bracher; Stanisa Raspopovic
Published in: iScience, 25 (4), Issue 3, 2022, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2022.104129

Towards enhanced functionality of vagus neuroprostheses through in silico optimized stimulation

Author(s): Federico Ciotti, Robert John, Natalija Katic Secerovic, Noemi Gozzi, Andrea Cimolato, Naveen Jayaprakash, Weiguo Song, Viktor Toth, Theodoros Zanos, Stavros Zanos, Stanisa Raspopovic
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-50523-6

Optimally-calibrated non-invasive feedback improves amputees' metabolic consumption, balance and walking confidence

Author(s): Lauren Chee; Giacomo Valle; Michele Marazzi; Greta Preatoni; Florian L Haufe; Michele Xiloyannis; Robert Riener; Stanisa Raspopovic
Published in: Journal of Neural Engineering, 19 (4), Issue 3, 2022, ISSN 1741-2560
Publisher: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ac883b

Neural signal recording and processing in somatic neuroprosthetic applications. A review

Author(s): Stanisa Raspopovic, Andrea Cimolato, Alessandro Panarese, Fabio Vallone, Jaume del Valle, Silvestro Micera, Xavier Navarro
Published in: Journal of Neuroscience Methods, Issue 337, 2020, Page(s) 108653, ISSN 0165-0270
Publisher: Elsevier BV
DOI: 10.1016/j.jneumeth.2020.108653

Sensory feedback for limb prostheses in amputees.

Author(s): Stanisa Raspopovic; Giacomo Valle; Francesco Maria Petrini
Published in: Nature Materials, 20 (7), Issue 1, 2021, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.3929/ethz-b-000493362

Lightening the Perceived Prosthesis Weight with Neural Embodiment Promoted by Sensory Feedback

Author(s): Greta Preatoni, Giacomo Valle, Francesco M. Petrini, Stanisa Raspopovic
Published in: Current Biology, 2021, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/j.cub.2020.11.069

Reshaping the full body illusion through visuo-electro-tactile sensations

Author(s): Greta Preatoni, Francesca Dell’Eva, Giacomo Valle, Alessandra Pedrocchi, Stanisa Raspopovic
Published in: PLOS ONE, Issue 18, 2023, Page(s) e0280628, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0280628

Cognitive benefits of using non-invasive compared to implantable neural feedback

Author(s): Chee, Lauren; Valle, Giacomo; Preatoni, Greta; Basla, Chiara; Marazzi, Michele; Raspopovic, Stanisa
Published in: Scientific Reports, 12 (1), Issue 1, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-21057-y

Microneurography as a tool to develop decoding algorithms for peripheral neuro-controlled hand prostheses

Author(s): Francesco M. Petrini, Alberto Mazzoni, Jacopo Rigosa, Federica Giambattistelli, Giuseppe Granata, Beatrice Barra, Alessandra Pampaloni, Eugenio Guglielmelli, Loredana Zollo, Marco Capogrosso, Silvestro Micera, Stanisa Raspopovic
Published in: BioMedical Engineering OnLine, Issue 18/1, 2019, ISSN 1475-925X
Publisher: BioMed Central
DOI: 10.1186/s12938-019-0659-9

Sensory feedback restoration in leg amputees improves walking speed, metabolic cost and phantom pain

Author(s): Francesco Maria Petrini, Marko Bumbasirevic, Giacomo Valle, Vladimir Ilic, Pavle Mijović, Paul Čvančara, Federica Barberi, Natalija Katic, Dario Bortolotti, David Andreu, Knut Lechler, Aleksandar Lesic, Sanja Mazic, Bogdan Mijović, David Guiraud, Thomas Stieglitz, Asgeir Alexandersson, Silvestro Micera, Stanisa Raspopovic
Published in: Nature Medicine, Issue 25/9, 2019, Page(s) 1356-1363, ISSN 1078-8956
Publisher: Nature Publishing Group
DOI: 10.1038/s41591-019-0567-3

Enhancing functional abilities and cognitive integration of the lower limb prosthesis

Author(s): Francesco Maria Petrini, Giacomo Valle, Marko Bumbasirevic, Federica Barberi, Dario Bortolotti, Paul Cvancara, Arthur Hiairrassary, Pavle Mijovic, Atli Örn Sverrisson, Alessandra Pedrocchi, Jean-Louis Divoux, Igor Popovic, Knut Lechler, Bogdan Mijovic, David Guiraud, Thomas Stieglitz, Asgeir Alexandersson, Silvestro Micera, Aleksandar Lesic, Stanisa Raspopovic
Published in: Science Translational Medicine, Issue 11/512, 2019, Page(s) eaav8939, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.aav8939

Mechanisms of neuro-robotic prosthesis operation in leg amputees.

Author(s): Giacomo Valle; Albulena Saliji; Ezra Fogle; Andrea Cimolato; Francesco Maria Petrini; Stanisa Raspopovic
Published in: Science Advances, 7 (17), Issue 3, 2021, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abd8354

A computational model to design neural interfaces for lower-limb sensory neuroprostheses

Author(s): Marek Zelechowski, Giacomo Valle, Stanisa Raspopovic
Published in: Journal of NeuroEngineering and Rehabilitation, Issue 17/1, 2020, ISSN 1743-0003
Publisher: BioMed Central
DOI: 10.1186/s12984-020-00657-7

Modeling foot sole cutaneous afferents: FootSim

Author(s): Natalija Katic, Rodrigo Kazu Siqueira, Luke Cleland, Nicholas Strzalkowski, Leah Bent, Stanisa Raspopovic, Hannes Saal
Published in: iScience, Issue 26, 2024, Page(s) 105874, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2022.105874

Bionic blink improves real-time eye closure in unilateral facial paralysis

Author(s): Mar Cervera-Negueruela, Lauren Chee, Andrea Cimolato, Giacomo Valle, Markus Tschopp, Marcel Menke, Anthia Papazoglou, Stanisa Raspopovic
Published in: Journal of Neural Engineering, Issue 21, 2024, Page(s) 026020, ISSN 1741-2560
Publisher: Institute of Physics Publishing
DOI: 10.1088/1741-2552/ad35e7

Advancing limb neural prostheses

Author(s): Stanisa Raspopovic
Published in: Science, Issue 370/6514, 2020, Page(s) 290-291, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abb1073

Plastic changes in the brain after a neuro-prosthetic leg use

Author(s): Igor Petrusic; Giacomo Valle; Marko Dakovic; Dusan Damjanovic; Marko Bumbasirevic; Stanisa Raspopovic
Published in: Clinical Neurophysiology, 138, Issue 3, 2022, ISSN 1388-2457
Publisher: Elsevier BV
DOI: 10.1016/j.clinph.2022.04.001

A non-invasive wearable sensory leg neuroprosthesis: mechanical, electrical and functional validation

Author(s): Chiara Basla; Lauren Chee; Giacomo Valle; Stanisa Raspopovic
Published in: Journal of Neural Engineering, 19 (1), Issue 2, 2022, ISSN 1741-2552
Publisher: IOPScience
DOI: 10.1088/1741-2552/ac43f8

Design of an adaptable intrafascicular electrode (AIR) for selective nerve stimulation by model-based optimization

Author(s): Federico Ciotti, Andrea Cimolato, Giacomo Valle, Stanisa Raspopovic
Published in: PLOS Computational Biology, Issue 19, 2023, Page(s) e1011184, ISSN 1553-7358
Publisher: Public Library of Science (PLOS)
DOI: 10.1371/journal.pcbi.1011184

Multiparametric non-linear TENS modulation to integrate intuitive sensory feedback

Author(s): Vittoria Bucciarelli, Noemi Gozzi, Natalija Katic, Giovanna Aiello, Margherita Razzoli, Giacomo Valle, Stanisa Raspopovic
Published in: Journal of Neural Engineering, Issue 20, 2023, Page(s) 036026, ISSN 1741-2560
Publisher: Institute of Physics Publishing
DOI: 10.1088/1741-2552/acd4e8

Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation

Author(s): Giacomo Valle, Natalija Katic Secerovic, Dominic Eggemann, Oleg Gorskii, Natalia Pavlova, Francesco M. Petrini, Paul Cvancara, Thomas Stieglitz, Pavel Musienko, Marko Bumbasirevic, Stanisa Raspopovic
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-45190-6

Symbiotic electroneural and musculoskeletal framework to encode proprioception via neurostimulation: ProprioStim

Author(s): Andrea Cimolato, Federico Ciotti, Jelena Kljajić, Giacomo Valle, Stanisa Raspopovic
Published in: iScience, Issue 26, 2024, Page(s) 106248, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2023.106248

Automated calibration of somatosensory stimulation using reinforcement learning

Author(s): Luigi Borda, Noemi Gozzi, Greta Preatoni, Giacomo Valle, Stanisa Raspopovic
Published in: Journal of NeuroEngineering and Rehabilitation, Issue 20, 2023, ISSN 1743-0003
Publisher: BioMed Central
DOI: 10.1186/s12984-023-01246-0

Multifaceted understanding of human nerve implants to design optimized electrodes for bioelectronics

Author(s): Giacomo Valle, Giovanna Aiello, Federico Ciotti, Paul Cvancara, Tamara Martinovic, Tamara Kravic, Xavier Navarro, Thomas Stieglitz, Marko Bumbasirevic, Stanisa Raspopovic
Published in: Biomaterials, Issue 291, 2023, Page(s) 121874, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2022.121874