SOphisticated 3D cell culture scaffolds for Next Generation Barrier-on-chip In vitro moDels

Project Information

SONGBIRD

Grant agreement ID: 757444

DOI 10.3030/757444

Project closed

EC signature date 20 October 2017

Start date 1 January 2018

End date 31 March 2023

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

UPPSALA UNIVERSITET
Sweden

Publications

Peer reviewed articles (15)

Acoustic focusing of beads and cells in hydrogel droplets

Author(s): Anna Fornell, Hannah Pohlit, Qian Shi, Maria Tenje
Published in: Scientific Reports, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-86985-7

In-Line Analysis of Organ-on-Chip Systems with Sensors: Integration, Fabrication, Challenges, and Potential.

Author(s): Stefanie Fuchs; Sofia Johansson; Anders Ø. Tjell; Gabriel Werr; Torsten Mayr; Maria Tenje
Published in: ACS Biomaterials Science & Engineering, Issue 1, 2021, ISSN 2373-9878
Publisher: American Chemical Society
DOI: 10.1021/acsbiomaterials.0c01110

A practical guide to microfabrication and patterning of hydrogels for biomimetic cell culture scaffolds

Author(s): Maria Tenje, Federico Cantoni, Ana María Porras Hernández, Sean S. Searle, Sofia Johansson, Laurent Barbe, Maria Antfolk, Hannah Pohlit
Published in: Organs-on-a-Chip, Issue 2, 2020, Page(s) 100003, ISSN 2666-1020
Publisher: Elsevier BV
DOI: 10.1016/j.ooc.2020.100003

Confocal imaging dataset to assess endothelial cell orientation during extreme glucose conditions

Author(s): Ana María Porras Hernández, Laurent Barbe, Hannah Pohlit, Maria Tenje & Maria Antfolk
Published in: Scientific Data, Issue 9, 2022, ISSN 2052-4463
Publisher: Nature Research
DOI: 10.1038/s41597-022-01130-x

Cell chirality exhibition of brain microvascular endothelial cells is dependent on micropattern width

Author(s): Ana Maria Porras Hernandez, Maria Tenje, Maria Antfolk
Published in: RSC Advances, 2022, Page(s) 30135-30144, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2ra05434e

A microscopy-compatible temperature regulation system for single-cell phenotype analysis – demonstrated by thermoresponse mapping of microalgae

Author(s): Martin Andersson; Sofia Johansson; Henrik Bergman; Linhong Xiao; Lars Behrendt; Maria Tenje
Published in: Lab on a Chip, Issue 1, 2021, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0lc01288b

A simplified approach to control cell adherence on biologically derived in vitro cell culture scaffolds by direct UV-mediated RGD linkage

Author(s): Ana María Porras Hernández, Hannah Pohlit, Frida Sjögren, Liyang Shi, Dmitri Ossipov, Maria Antfolk, Maria Tenje
Published in: Journals of Materials Science: Materials in Medicine, 2020, ISSN 0957-4530
Publisher: Springer Nature
DOI: 10.1007/s10856-020-06446-x

An acoustofluidic platform for non-contact trapping of cell-laden hydrogel droplets compatible with optical microscopy.

Author(s): Fornell, Anna; Johannesson, Carl; Searle, Sean S.; Happstadius, Axel; Nilsson, Johan; Tenje, Maria
Published in: Biomicrofluidics, Issue 1, 2019, ISSN 1932-1058
Publisher: American Institute of Physics
DOI: 10.1063/1.5108583

A Perfusable Multi-Hydrogel Vasculature On-Chip Engineered by 2-Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels

Author(s): Federico Cantoni, Laurent Barbe, Hannah Pohlit, Maria Tenje
Published in: Advanced Materials Technologies, Issue 2300718, 2023, ISSN 2365-709X
Publisher: Wiley-VCH GmbH
DOI: 10.1002/admt.202300718

Organ-on-a-chip technology: a novel approach to investigate cardiovascular diseases

Author(s): Valentina Paloschi, Maria Sabater-Lleal, Heleen Middelkamp, Aisen Vivas, Sofia Johansson, Andries van der Meer, Maria Tenje, Lars Maegdefessel
Published in: Cardiovascular Research, 2021, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvab088

Photophysiological response of Symbiodiniaceae single cells to temperature stress

Author(s): Linhong Xiao, Sofia Johansson, Saskia Rughöft, Fabien Burki, Miguel Mendez Sandin, Maria Tenje, Lars Behrendt
Published in: Nature ISME Journal, 2022, ISSN 1751-7362
Publisher: Nature Publishing Group
DOI: 10.1038/s41396-022-01243-6

A droplet acoustofluidic platform for time-controlled microbead-based enzymatic reactions

Author(s): Zhenhua Liu, Anna Fornell, Maria Tenje
Published in: Biomicrofluidics, 2021, ISSN 1932-1058
Publisher: American Institute of Physics
DOI: 10.1063/5.0050440

A microfluidic chip carrier including temperature control and perfusion system for long-term cell imaging

Author(s): Federico Cantoni, Gabriel Werr, Laurent Barbe, Ana Maria Porras, Maria Tenje
Published in: HardwareX, 2021, ISSN 2468-0672
Publisher: Elsevier
DOI: 10.1016/j.ohx.2021.e00245

Binary acoustic trapping in a glass capillary

Author(s): Anna Fornell, Thierry Baasch, Carl Johannesson, Johan Nilsson, Maria Tenje
Published in: Journal of Physics D: Applied Physics, 2021, Page(s) 355401, ISSN 0022-3727
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6463/ac0841

Brain microvasculature endothelial cell orientation on micropatterned hydrogels is afected by glucose level variations

Author(s): Ana María Porras Hernández, Laurent Barbe, Hannah Pohlit, MariaTenje & MariaAntfolk
Published in: Scientific Reports, Issue 11, 2021, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-021-99136-9

Thesis and dissertations (1)

Micropatterning of hyaluronic acid hydrogels for in vitro models

Author(s): Ana María Porras Hernández
Published in: 2022, ISBN 978-91-513-1508-9
Publisher: Acta Universitatits Upsaliensis