A multidisciplinary approach for the stratification of patients with carotid artery disease

Livrables

Results of the clinical study

A document with the results of the clinical study

Communication and dissemination activities v3

The final report about the Communication and dissemination activities

Communication and dissemination activities v2

A second version of a report about Communication and dissemination activities

Communication and dissemination activities v1

A first version of report for the Communication and dissemination activities

Project handbook, risk management and quality assurance plan

This deliverable will gather and define the project vision, the key activities and milestones, the main stakeholders and will form the basis for the successful project completion. Moreover, it concerns the risk management processes and established measures to ensure the smooth execution of the project.

Report on Gender and Equal Opportunities

This deliverable will provide sex-disaggregated data on the project workforce, on the impact of the working environment and on the career and professional mobility.

Regulatory strategy planning

A report which summarise the Regulatory strategy planning

Cost effectiveness analysis and impact assessment

A document with the results of the cost effectiveness analysis and impact assessment

Report on status of posting results
Midterm recruitment report

A report about the midterm recruitment report

First study subject approvals package

A report about first study subject approvals package

Final report on status of posting results

A document which describes the final report on status of posting results

Regulatory aspects of clinical practice

A document with the regulatory aspects of clinical practice

Project presentation material

This deliverable will present the material for the presentation of the project

Publications

Analysis of carotid plaque type based on deep learning techniques

Auteurs: Branko Arsic, Smiljana Djorovic, Milos Anic, Igor Saveljic, Igor Koncar, Nenad Filipovic
Publié dans: VPH2020 Conference, Paris 26-28 August 2020, 2020
Éditeur: VPH Institute
DOI: 10.5281/zenodo.4562420

Early Diagnosis of Carotid Artery Disease based on non-imaging data

Auteurs: Vassiliki I. Kigka, Antonis I. Sakellarios, Vassilis D. Tsakanikas, Vassiliki T. Potsika, Igor Koncar and Dimitrios I. Fotiadis
Publié dans: 2023
Éditeur: IEEE
DOI: 10.5281/zenodo.10724763

Computational modeling of atherosclerotic plaque progression incarotid lesions with moderate degree of stenosis

Auteurs: Michalis, M., Siogkas, P., Tsakanikas, V., Potsika, V., Pleouras, D., Sakellarios, N., Karagiannis, G., Galyfos, G., Sigala, F., Liasis, N., Jovanovic, M., Koncar, I. B., Kallmayer, M., & Fotiadis, D
Publié dans: 2021
Éditeur: IEEE
DOI: 10.5281/zenodo.10819653

SEGNET ARCHITECTURE BASED MODEL FOR CAROTID ARTERY SEGMENTATION

Auteurs: Nikola Radovanovic; Lazar Dasic; Nenad Filipovic
Publié dans: Numéro 7, 2022
Éditeur: University of Kragujevac
DOI: 10.5281/zenodo.7108673

3D reconstruction of patient-specific carotid artery geometry using clinical ultrasound imaging

Auteurs: Tijana Djukic, Branko Arsic, Igor Koncar, Nenad Filipovic
Publié dans: The 23rd International Conference on Medical Image Computing and Computer Assisted Intervention, 2020
Éditeur: MICCAI
DOI: 10.5281/zenodo.4563917

MRI vs. US 3D computational models of carotid arteries: a Fluid Structure Interaction case-study

Auteurs: Panagiotis K. Siogkas; Vassilis D. Tsakanikas; Antonis I. Sakellarios; Dimitrios Pleouras; Vassiliki T. Potsika; Evdokia Karamouzi; Foteini Lagiou; George Galyfos; Fragiska Sigala; Igor Koncar; Smiljana Tomašević; Tijana Djukic; Nenad Filipovic; Dimitrios I. Fotiadis
Publié dans: HSTAM 2022 conference, Numéro 2022, 2022
Éditeur: HSTAM 2022 conference
DOI: 10.5281/zenodo.7106845

DEEP LEARNING METHODS FOR PLAQUE TYPE CLASSIFICATION BASED ON THE US IMAGES OF CAROTID ARTERY

Auteurs: Branko Arsic; Smiljana Djorovic; Milos Anic; Igor Saveljic; Igor Koncar; Nenad Filipovic
Publié dans: Numéro 23, 2021
Éditeur: The European Society of Biomechanics
DOI: 10.5281/zenodo.7108587

TAXINOMISIS: A cloud – based platform for risk profiling and patient specific management of the carotid artery disease

Auteurs: Vassilis D. Tsakanikas, Panagiotis K. Siogkas, Vassiliki T. Potsika, Dimitris S. Pleouras, Vassiliki I.Kigka, Themis P. Exarchos, Igor B. Koncar and Dimitrios I. Fotiadis
Publié dans: 2023
Éditeur: IEEE
DOI: 10.5281/zenodo.10723046

Computational modeling of atherosclerotic plaque progression through an efficient 3D agent-based modeling approach

Auteurs: Tsompou, P., Potsika, V., Petrovic, N., Pezoulas, V., Siogkas, P., Tsakanikas, V., Pleouras, D., Papafaklis, M., Nikopoulos, S., Sakellarios, A., & Fotiadis, D.
Publié dans: 2022
Éditeur: IEEE
DOI: 10.5281/zenodo.10812157

Carotid Plaque Segmentation, Classification, 3D Reconstruction and Risk Stratification Using Ultrasound Images

Auteurs: Filipovic N, Arsic B, Djukic T, Djorovic S.
Publié dans: 2021
Éditeur: USACM

Combining deep learning and meshing techniques for automatic segmentation and 3D reconstruction of atherosclerotic carotid arteries

Auteurs: Smiljana Tomasevic, Tijana Djukic, Branko Arsic, Milos Anic, Andjela Blagojevic, Branko Gakovic, Igor Koncar, Nenad Filipovic
Publié dans: 2023
Éditeur: ICCB 2023
DOI: 10.5281/zenodo.10519332

Accurate adventitia reconstruction; significant or not in atherosclerotic plaque growth simulations: A comparative study

Auteurs: Dimitrios S. Pleouras, Panagiotis K. Siogkas, Vasilis D. Tsakanikas, Michalis D. Mantzaris, Vassiliki T. Potsika, Antonis Sakellarios, Fragiska Sigala, and Dimitrios I. Fotia
Publié dans: 2023
Éditeur: IEEE
DOI: 10.5281/zenodo.10720648

Application of deep learning techniques for segmentation of atherosclerotic carotid arteries by using ultrasound images

Auteurs: Arsić, B., Djorovic, S., Anić, M., Saveljić, I., Končar, I., Filipović, N.
Publié dans: Proceedings of the 11th International Conference on Information Society and Technology, 2021, Page(s) 135-138, ISBN 978-86-85525-24-7
Éditeur: Information Society of Serbia - ISOS

MRI vs. US 3D computational models of carotid arteries: a proof-of-concept study

Auteurs: Panagiotis K. Siogkas, Vassilis D. Tsakanikas, Antonis I. Sakellarios, Vassiliki T. Potsika, George Galyfos, Fragiska Sigala, Smiljana Tomašević, Tijana Djukic, Nenad Filipovic, Igor Koncar, & Dimitrios I. Fotiadis.
Publié dans: IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI), 2022
Éditeur: IEEE
DOI: 10.5281/zenodo.7106854

Validation of the machine learning approach for 3D reconstruction of carotid artery from ultrasound imaging

Auteurs: Tijana Djukic, Branko Arsic, Smiljana Djorovic, Igor Koncar, Nenad Filipovic
Publié dans: The 20th IEEE International Conference on BioInformatics And BioEngineering, 2020
Éditeur: IEEE
DOI: 10.5281/zenodo.4563909

Convolutional Neural Network for Atherosclerotic Plaque Multiclass Semantic Image Segmentation in Transverse Ultrasound Images of Carotid Artery

Auteurs: Lazar Dašić, Ognjen Pavić, Andjela Blagojević, Tijana Geroski, Nenad Filipović
Publié dans: 2023
Éditeur: Springer
DOI: 10.1007/978-3-031-50755-7_10

Atherosclerotic Plaque Characterization Using Deep Learning Methods

Auteurs: Smiljana Tomasevic; Branko Arsic; Milos Anic; Branko Gakovic; Igor Koncar; Nenad Filipovic
Publié dans: Numéro 25, 2022
Éditeur: The European Society for CardioVascular and Endovascular Surgery
DOI: 10.5281/zenodo.7108702

Comparison Between Patch-based and Whole Image Atherosclerotic Carotid Plaque Multiclass Image Segmentation using Convolutional Neural Networks

Auteurs: Lazar Dašić, Anđela Blagojević, Tijana Šušteršič, Nenad Filipović
Publié dans: 2022
Éditeur: EEE-EMBS
DOI: 10.5281/zenodo.10573365

AGENT-BASED MODEL AND SIMULATION OF ATHEROSCLEROTIC PLAQUE PROGRESSION

Auteurs: Andjela Blagojevic; Tijana Sustersic; Nenad Filipovic
Publié dans: Numéro 4, 2022
Éditeur: VPH Institute
DOI: 10.5281/zenodo.7108608

Simulation of blood flow through a patient-specific carotid bifurcation reconstructed using deep learning based segmentation of ultrasound images

Auteurs: Tijana Djukic, Milos Anic, Branko Gakovic, Smiljana Tomasevic, Branko Arsic, Igor Koncar, Nenad Filipovic
Publié dans: 2023
Éditeur: University of Kragujevac
DOI: 10.5281/zenodo.10519018

ANALYSIS OF ATHEROSCLEROTIC PLAQUE IN CAROTID ARTERIES BY USING CONVOLUTIONAL NEURAL NETWORKS

Auteurs: Branko Arsic; Smiljana Djorovic; Milos Anic; Branko Gakovic; Igor Koncar; Nenad Filipovic
Publié dans: Numéro 10, 2021
Éditeur: Serbian Society of Mechanics
DOI: 10.5281/zenodo.7108523

Modeling of Plaque Progression in the Carotid Artery Using Coupled Agent Based with Finite Element Method

Auteurs: N. Filipovic, S. Tomasevic, A. Blagojevic, B. Arsic, M. Anic and T. Djukic
Publié dans: 2022
Éditeur: IEEE-EMBS
DOI: 10.1109/bhi56158.2022.9926817

A multimodal advanced approach for the stratification of carotid artery disease

Auteurs: Michalis Mantzaris; Vassiliki Potsika; Panagiotis Siogkas; Vassiliki Kigka; Vasileios Pezoulas; Ioannis Pappas; Themis Exarchos; Igor Koncar; Jaroslav Pelisek; Evangelos Andreakos; Dimitrios I. Fotiadis
Publié dans: 19thAnnual IEEE International Conference on Bioinformatics andBioengineering, Athens, Greece, 2019
Éditeur: IEEE
DOI: 10.5281/zenodo.4400031

A deep learning oriented method for automated 3D reconstruction of carotid arterial trees from MR imaging

Auteurs: Vassilis D. Tsakanikas; Panagiotis K. Siogkas; Michalis D. Mantzaris; Vassiliki T. Potsika; Vassiliki I. Kigka; Themis P. Exarchos; Igor B. Koncar; Marija Jovanović; Aleksandra Vujčić; Stefan Dučić; Jaroslav Pelisek; Dimitrios I. Fotiadis
Publié dans: 42nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Montréal, Québec, Canada, 2020
Éditeur: IEEE
DOI: 10.5281/zenodo.3968549

Automatic segmentation and 3D reconstruction of patient-specific carotid artery by using ultrasound images

Auteurs: Anic, Milos; Arsic, Branko; Djukic, Tijana; Tomasevic, Smijana; Gakovic, Branko; Koncar, Igor; Filipovic, Nenad
Publié dans: Numéro 2, 2023
Éditeur: University of Kragujevac
DOI: 10.5281/zenodo.10519119

Agent Based with Finite Element Method for Plaque Progression in the Carotid Artery

Auteurs: Nenad Filipovic, Smiljana Tomasevic, Branko Arsic, Milos Anic, Tijana Djukic, Igor Koncar
Publié dans: 2023
Éditeur: IEEE
DOI: 10.1109/dsp58604.2023.10167917

Computational modeling and big data approaches for the stratification of carotid artery disease

Auteurs: Michalis D. Mantzaris, Vassiliki T. Potsika, Panagiotis K. Siogkas, Ioannis G. Pappas, Themis P. Exarchos, Member, IEEE, Igor B. Koncar, Jaroslav Pelisek, Evangelos Andreakos and Dimitrios I. Fotiadis
Publié dans: Computational modeling and big data approaches for the stratification of carotid artery disease, Numéro 1, 2019
Éditeur: IEEE
DOI: 10.5281/zenodo.3250574

A Multilevel Approach to Evaluate Numerically Plaque Progression in Carotid Artery Disease

Auteurs: Vassiliki T. Potsika, Michalis D. Mantzaris, Panagiotis K. Siogkas, Ioannis G. Pappas, Themis P. Exarchos, Dimitrios I. Fotiadis
Publié dans: 8th Panhellenic Congress of Biomedical Technology, Numéro 1, 2019
Éditeur: 8th Panhellenic Congress of Biomedical Technology
DOI: 10.5281/zenodo.3250568

Numerical Analysis of Plaque Progression in 3D Patient Specific Model of Carotid Artery

Auteurs: Smiljana Djorovic, Igor Saveljic, Nenad Filipovic
Publié dans: CMBEBIH 2019 - Proceedings of the International Conference on Medical and Biological Engineering, 16 ̶̶ 18 May 2019, Banja Luka, Bosnia and Herzegovina, Numéro 73, 2020, Page(s) 337-340, ISBN 978-3-030-17970-0
Éditeur: Springer International Publishing
DOI: 10.1007/978-3-030-17971-7_52

Lipidome improves predictive ability of subclinical atherosclerosis over traditional risk factors: The Cardiovascular Risk in Young Finns Study

Auteurs: Pashupati P. Mishra Leo-Pekka Lyytikäinen Binisha H. Mishra Mika Kähönen Olli T. Raitakari Reijo Laaksonen Terho Lehtimäki
Publié dans: 15th Annual conference of the Metabolomics Society, 2019
Éditeur: Metabolomics Society
DOI: 10.5281/zenodo.3250843

Ceramides improve prediction accuracy of subclinical atherosclerosis

Auteurs: Pashupati P. Mishra Leo-Pekka Lyytikäinen Mika Kähönen Olli T. Raitakari Reijo Laaksonen Terho Lehtimäki
Publié dans: European Conference on Computational Biology 2018, 2018
Éditeur: European Conference on Computational Biology
DOI: 10.5281/zenodo.3250838

Three-dimensional numerical analysis of atherosclerosis development within carotid artery

Auteurs: Djorovic Smiljana; Saveljic Igor; Filipovic Nenad
Publié dans: Numéro 2, 2019
Éditeur: IEEE
DOI: 10.5281/zenodo.3253176

Analysis of the carotid artery and atherosclerotic plaque growth using the patient-specific parameters

Auteurs: Djorovic Smiljana; Saveljic Igor; Filipovic Nenad
Publié dans: Numéro 2, 2019
Éditeur: European Society of CardioVascular and Endovascular Surgery (ESCVS)
DOI: 10.5281/zenodo.3253178

Carotid atherosclerosis disease: modelling and analysis of plaque development

Auteurs: Djorovic Smiljana; Saveljic Igor; Filipovic Nenad
Publié dans: Numéro 2, 2019
Éditeur: European Society of Biomechanics - ESBiomech Conference 2019 (ESB)
DOI: 10.5281/zenodo.3253204

Computational modelling of carotid artery and simulation of plaque progression

Auteurs: Djorovic Smiljana; Saveljic Igor; Filipovic Nenad
Publié dans: Numéro 2, 2019
Éditeur: Serbian Society of Mechanics
DOI: 10.5281/zenodo.3253189

On-chip SNPs detection for stratification of patients with carotid artery disease

Auteurs: Wiederkehr, R. S., Marchal, E., Forceville, T., Taher, A., Uribe, A. J., Zinoviev, K., Siouti, L., Choe, Y. J., Potsika, V. T., Andreakos, E., & Stakenborg, T.
Publié dans: 2023
Éditeur: CYTOKINES
DOI: 10.5281/zenodo.10818061

A Machine Learning Model for the Identification of High risk Carotid Atherosclerotic Plaques

Auteurs: Vassiliki I. Kigka, Antonis I. Sakellarios, Michalis D. Mantzaris, Vassilis D. Tsakanikas, Vassiliki T. Potsika, Domenico Palombo, Fabrizio Montecucco and Dimitrios I. Fotiadis,
Publié dans: 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2021
Éditeur: IEEE
DOI: 10.5281/zenodo.10826347

IMPROVED THREE-DIMENSIONAL RECONSTRUCTION OF PATIENT-SPECIFIC CAROTID BIFURCATION USING DEEP LEARNING BASED SEGMENTATION OF ULTRASOUND IMAGES

Auteurs: Milos Anic; Tijana Djukic; Branko Gakovic; Branko Arsic; Nenad Filipovic
Publié dans: Numéro 23, 2022
Éditeur: University of Kragujevac
DOI: 10.5281/zenodo.7108651

Enhancing risk prediction capabilities in patients with carotid artery disease using a 2-level computational approach

Auteurs: Siogkas Panagiotis, Pleouras Dimitrios, Tsakanikas Vasilis, Mantzaris Michalis, Potsika Vassiliki, Sakellarios Antonis, Charalampopoulos George, Galyfos George, Sigala Fragkiska, Fotiadis Dimitrios
Publié dans: 2023
Éditeur: IEEE
DOI: 10.5281/zenodo.10720538

Detection of Asymptomatic Carotid Artery Stenosis through Machine Learning

Auteurs: Vassiliki I. Kigka; Antonis I. Sakellarios; Vassilis D. Tsakanikas; Vassiliki T. Potsika; Igor Koncar; Dimitrios I. Fotiadis
Publié dans: EMBC 2022, Numéro 2022, 2022
Éditeur: IEEE
DOI: 10.5281/zenodo.7110135

Coupling Agent Based Method and Computational Fluid Dynamics for Plaque Development in the Carotid Artery

Auteurs: Nenad Filipovic, Andjela Blagojević, Smiljana Djorovic, Branko Arsic, Tijana Djukic
Publié dans: Virtual Physiological Human Conference (VPH2022), 2022
Éditeur: VPH Institute
DOI: 10.5281/zenodo.10573264

Automatic segmentation and 3D reconstruction of plaque components in carotid artery from ultrasound images

Auteurs: Tijana Djukic; Branko Arsic; Smiljana Tomasevic; Branko Gakovic; Igor Koncar; Nenad Filipovic
Publié dans: Numéro 7, 2021
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.5281/zenodo.7108549

Integrating deep learning and meshing techniques to perform 3D reconstruction of patient-specific carotid bifurcation with plaque classification

Auteurs: Tijana Djukic, Smiljana Tomasevic, Branko Arsic, Branko Gakovic, Nenad Filipovic
Publié dans: 2022
Éditeur: EEE-EMBS
DOI: 10.5281/zenodo.10518163

Simulation of Atherosclerotic Plaque Development using Agent-based Modelling

Auteurs: Blagojević, A., Šušteršič, T., Filipović, N.
Publié dans: Proceedings of the 11th International Conference on Information Society and Technology, 2021, Page(s) 55-58, ISBN 978-86-85525-24-7
Éditeur: Information Society of Serbia - ISOS

A Machine Learning Model for the prediction of the progression of carotid arterial stenoses

Auteurs: Panagiotis K. Siogkas, Dimitrios S. Pleouras, Vasilis D. Tsakanikas, Vassiliki T. Potsika, Antonis Sakellarios,Evdokia Karamouzi, Foteini Lagiou, George Charalampopoulos, George Galyfos,Fragiska Sigala, Igor Koncar and Dimitrios I. Fotiadi
Publié dans: 2023
Éditeur: IEEE
DOI: 10.5281/zenodo.10720597

3D RECONSTRUCTION OF PATIENT-SPECIFIC CAROTID ARTERY GEOMETRY FROM 2D ULTRASOUND IMAGES

Auteurs: Jovana Nikolic; Nenad Filipovic
Publié dans: Numéro 7, 2022
Éditeur: University of Kragujevac
DOI: 10.5281/zenodo.7108683

3D modeling of carotid artery and plaque progression using coupled agent based and finite element methods

Auteurs: Smiljana Tomasevic, Tijana Djukic, Branko Arsic, Milos Anic, Andjela Blagojevic, Branko Gakovic, Igor Koncar, Nenad Filipovic
Publié dans: 2023
Éditeur: ESB
DOI: 10.5281/zenodo.10519182

Processing of ultrasound images by using convolutional neural networks for carotid artery detection and segmentation

Auteurs: Branko Arsic, Smiljana Djorovic, Milos Anic, Igor Koncar, Nenad Filipovic
Publié dans: 2021
Éditeur: CMBBE

Investigation of the effect of atherosclerotic plaque location on the progression of luminal stenosis in carotids.

Auteurs: Pleouras Dimitrios; Mantzaris Michalis; Siogkas Panagiotis; Tsakanikas Vasilis; Potsika Vasiliki; Sakellarios Antonis; Dimos Sokratis; Sigala Fragiska; Koncar Igor; Tomasevic Smiljana; Djuskic Tijana; Filipovic Nenad; Fotiadis Dimitrios
Publié dans: HSTAM 2022 conference, 2022
Éditeur: HSTAM OC
DOI: 10.5281/zenodo.7064478

Simulation of Atherosclerotic Plaque Development using Agent-based Modelling

Auteurs: Blagojević A, Šušteršič T, Filipović N.
Publié dans: 2022
Éditeur: Information Society of Serbia - ISOS

Prediction of the atherosclerotic plaque development in carotid arteries; the effect of T-cells

Auteurs: Pleouras Dimitrios Mechanical Engineer, Researcher ; Mantzaris Michalis; Siogkas Panagiotis; Tsakanikas Vasilis; Potsika Vassiliki; Sakellarios Antonis; Tsompou Panagiota; Sigala Fragiska; Fotiadis Dimitrios
Publié dans: EMBC 2022 conference, Numéro 2022, 2022
Éditeur: IEEE
DOI: 10.5281/zenodo.7064421

The TAXINOMISIS Project: A multidisciplinary approach for thedevelopment of a new risk stratification model for patients with asymptomaticcarotid artery stenosis.

Auteurs: Timmerman N, Galyfos G, Sigala F, Thanopoulou K, de Borst GJ, Davidovic L, Eckstein HH, Filipovic N, Grugni R, Kallmayer M, de Kleijn DPV, Koncar I, Mantzaris MD, Marchal E, Matsagkas M, Mutavdzic P, Palombo D, Pasterkamp G, Potsika VT, Andreakos E, Fotiadis DI
Publié dans: European journal of vascular and endovascular surgery, 2020, ISSN 1078-5884
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1111/eci.13411

Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis, increasing the risk of cerebrovascular complications

Auteurs: Lea Dib, Lada A. Koneva, Andreas Edsfeldt, Yasemin-Xiomara Zurke, Jiangming Sun, Mihaela Nitulescu, Moustafa Attar, Esther Lutgens, Steffen Schmidt, Marie W. Lindholm, Robin P. Choudhury, Ismail Cassimjee, Regent Lee, Ashok Handa, Isabel Goncalves, Stephen N. Sansom, Claudia Monaco
Publié dans: Nature Cardiovascular Research, 2023, Page(s) 656–672, ISSN 2731-0590
Éditeur: /
DOI: 10.1038/s44161-023-00295-x

Patch-based Convolutional Neural Network for Atherosclerotic Carotid Plaque Semantic Segmentation

Auteurs: Dašić Lazar, Radovanović Nikola, Šušteršič Tijana, Blagojević Anđela, Benolić Leo, Filipović Nenad
Publié dans: IPSI Transactions on Internet Research, Numéro 1, 18, 2022, ISSN 1820-4503
Éditeur: IPSI BgD

Ceramides andphospholipids in plasma extracellular vesicles are associated with high risk ofmajor cardiovascular events after carotid endarterectomy.

Auteurs: Timmerman N, Waissi F, Dekker M, de Borst GJ, van Bennekom J, de Winter RJ, Hilvo M, Jylhä A, Pasterkamp G, de Kleijn DPV, Laaksonen R.
Publié dans: Scientific Reports, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-09225-6

Cardiovascular health trajectories from childhood through middle age and their association with subclinical atherosclerosis

Auteurs: Allen , N. B., Krefman, A. E., Labarthe, D., Greenland, P., Juonala, M., Kähönen, M., ... & Lloyd-Jones, D. M
Publié dans: JAMA cardiology, 2020, ISSN 2380-6591
Éditeur: American Medical Association
DOI: 10.1001/jamacardio.2020.0140

Elevated Lp(a) (Lipoprotein[a]) Levels Increase Risk of 30-Day Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy

Auteurs: Farahnaz Waissi, Mirthe Dekker, Nathalie Timmerman, Renate M. Hoogeveen, Joelle van Bennekom, Kim E. Dzobo, Johan G. Schnitzler, Gerard Pasterkamp, Diederick E. Grobbee, Gert J. de Borst, Erik S.G. Stroes, Dominique P.V. de Kleijn, Jeffrey Kroon
Publié dans: Stroke, Numéro 51, 2020, Page(s) 2972–2982, ISSN 0039-2499
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.120.030616

Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics

Auteurs: Marie A.C. Depuydt, Koen H.M. Prange, Lotte Slenders, Tiit Örd, Danny Elbersen, Arjan Boltjes, Saskia C.A. de Jager, Folkert W. Asselbergs, Gert J. de Borst, Einari Aavik, Tapio Lönnberg, Esther Lutgens, Christopher K. Glass, Hester M. den Ruijter, Minna U. Kaikkonen, Ilze Bot, Bram Slütter, Sander W. van der Laan, Seppo Yla-Herttuala, Michal Mokry, Johan Kuiper, Menno P.J. de Winther, Gerard P
Publié dans: Circulation Research, Numéro 127/11, 2020, Page(s) 1437-1455, ISSN 0009-7330
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.120.316770

RNA-sequencing reveals that STRN, ZNF484 and WNK1 add to the value of mitochondrial MT-COI and COX10 as markers of unstable coronary artery disease

Auteurs: Holvoet , P., Klocke, B., Vanhaverbeke, M., Menten, R., Sinnaeve, P., Raitoharju, E., ... & Cagnin
Publié dans: Plos One, 2019, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0225621

Risk Factors for Ischemic Stroke After Acute Coronary Syndrome

Auteurs: Hurskainen M, Tynkkynen J, Eskola M, Lehtimäki T, & Hernesniemi J
Publié dans: Journal of the American Heart Association, 2023, ISSN 2047-9980
Éditeur: Wiley-Blackwell
DOI: 10.1161/jaha.122.028787

Characteristics of peripheral blood cells are independently related to major adverse cardiovascular events after carotid endarterectomy

Auteurs: Overmars LM, Mekke JM, van Solinge WW, De Jager SCA, Hulsbergen-Veelken CAR, Hoefer IE, de Kleijn DPV, de Borst GJ, van der Laan SW, Haitjema S.
Publié dans: Atheroscler Plus., Numéro 2023 Jun 1;52:32-40, 2023, Page(s) 32-40, ISSN 2667-0895
Éditeur: Elsevier
DOI: 10.1016/j.athplu.2023.05.003

Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis–Tampere Vascular Study

Auteurs: Rinne , P., Lyytikäinen, L. P., Raitoharju, E., Kadiri, J. J., Kholova, I., Kähönen, M., ... & Oksala, N
Publié dans: Scientific Reports, 2018, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-018-33523-7

High lipoprotein(a) is associated with major adverse limb events after femoral artery endarterectomy

Auteurs: Verwer MC, Waissi F, Mekke JM, Dekker M, Stroes ESG, de Borst GJ, Kroon J, Hazenberg CEVB, de Kleijn DPV.
Publié dans: Atherosclerosis, Numéro 2022 May;349:196-203, 2022, Page(s) 196-203, ISSN 0021-9150
Éditeur: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2021.11.019

Plasma Lipoprotein Lipase Is Associated with Risk of Future Major Adverse Cardiovascular Events in Patients Following Carotid Endarterectomy.

Auteurs: Mekke JM, Verwer MC, Stroes ESG, Kroon J, Timmers L, Pasterkamp G, de Borst GJ, van der Laan SW, de Kleijn DPV
Publié dans: Eur J Vasc Endovasc Surg, Numéro 2023 May;65(5):700-709, 2023, Page(s) 700-709, ISSN 1078-5884
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.ejvs.2023.01.035

Lipidomic architecture shared by subclinical markers of osteoporosis and atherosclerosis: The Cardiovascular Risk in Young Finns Study

Auteurs: Mishra , B. H., Mishra, P. P., Mononen, N., Hilvo, M., Sievänen, H., Juonala, M., ... & Lehtimäki, T
Publié dans: Bone, 2020, ISSN 8756-3282
Éditeur: Elsevier BV
DOI: 10.1016/j.bone.2019.115160

Atherosclerotic Plaque Characterization Using Deep Learning Methods

Auteurs: Branko Arsic, Smiljana Tomasevic, Milos Anic, Branko Gakovic, Igor Koncar, Nenad Filipovic
Publié dans: AORTA, 2022, ISSN 2325-4637
Éditeur: Thieme Medical Publishers, Inc.
DOI: 10.1055/s-0042-1750994

Thrombus Aspirates From Patients With Acute Ischemic Stroke Are Infiltrated by Viridans Streptococci

Auteurs: Patrakka , O., Tuomisto, S., Pienimäki, J. P., Ollikainen, J., Oksala, N., Lampinen, V., ... & Karhunen, P. J
Publié dans: Journal of the American Heart Association, 2023, ISSN 2047-9980
Éditeur: Wiley-Blackwell
DOI: 10.1161/jaha.123.030639

Uncovering the shared lipidomic markers of subclinical osteoporosis-atherosclerosis comorbidity: The Young Finns Study

Auteurs: Binisha H. Mishra, Pashupati P. Mishra, Nina Mononen, Mika Hilvo, Harri Sievänen, Markus Juonala, Marika Laaksonen, Nina Hutri-Kähönen, Jorma Viikari, Mika Kähönen, Olli T. Raitakari, Reijo Laaksonen, Terho Lehtimäk
Publié dans: Bone, 2021, ISSN 8756-3282
Éditeur: Elsevier BV
DOI: 10.1016/j.bone.2021.116030

Palmitoylethanolamide promotes a proresolving macrophage phenotype and attenuates atherosclerotic plaque formation

Auteurs: Rinne , P., Guillamat-Prats, R., Rami, M., Bindila, L., Ring, L., Lyytikäinen, L. P., ... & Steffens, S
Publié dans: Arteriosclerosis, thrombosis, and vascular biology, 2018, ISSN 1079-5642
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.118.311185

Common Variants Associated With OSMR Expression Contribute to Carotid Plaque Vulnerability, but Not to Cardiovascular Disease in Humans

Auteurs: Danielle van Keulen, Ian D. van Koeverden, Arjan Boltjes, Hans M. G. Princen, Alain J. van Gool, Gert J. de Borst, Folkert W. Asselbergs, Dennie Tempel, Gerard Pasterkamp Sander W. van der Laan
Publié dans: Frontiers in cardiovascular medicine, Numéro 2021; 8: 658915, 2021, Page(s) 1-10, ISSN 2297-055X
Éditeur: Frontiers
DOI: 10.3389/fcvm.2021.658915

Pre-Operative Plasma Extracellular Vesicle Proteins are Associated with a High Riskof Long Term Secondary Major Cardiovascular Events in Patients UndergoingCarotid Endarterectomy.

Auteurs: Timmerman N, Waissi F, Dekker M, van de Pol QY, van Bennekom J, Schoneveld A, Klein Avink MJM, de Winter RJ, Pasterkamp G, de Borst GJ, de Kleijn DPV.
Publié dans: european journal of vascular and endovascular surgery, 2021, ISSN 1078-5884
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.ejvs.2021.06.039

The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological symptoms

Auteurs: Mekke JM, Sakkers TR, Verwer MC, van den Dungen NAM, Song Y, Miller CL, Finn AV, Pasterkamp G, Mokry M, den Ruijter HM, Vink A, de Kleijn DPV, de Borst GJ, Haitjema S, van der Laan SW.
Publié dans: Scientific reports, Numéro 2023 Oct 10;13(1):17104., 2023, Page(s) 17104, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-43369-3

Carotid Artery Segmentation Using Convolutional Neural Network in Ultrasound Images

Auteurs: Radovanović Nikola, Dašić Lazar, Blagojević Anđela, Šušteršič Tijana, Filipović Nenad
Publié dans: IPSI Transactions on Internet Research, Numéro 1, 18, 2022, ISSN 1820-4503
Éditeur: IPSI BgD

Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation

Auteurs: Johan G. Schnitzler, Renate M. Hoogeveen, Lubna Ali, Koen H.M. Prange, Farahnaz Waissi, Michel van Weeghel, Julian C. Bachmann, Miranda Versloot, Matthew J. Borrelli, Calvin Yeang, Dominique P.V. De Kleijn, Riekelt H. Houtkooper, Marlys L. Koschinsky, Menno P.J. de Winther, Albert K. Groen, Joseph L. Witztum, Sotirios Tsimikas, Erik S.G. Stroes, Jeffrey Kroon
Publié dans: Circulation Research, Numéro 126, 2020, Page(s) 1346–1359, ISSN 0009-7330
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.316206

C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis

Auteurs: Inhye Park, Michael E. Goddard, Jennifer E. Cole, Natacha Zanin, Leo-Pekka Lyytikäinen, Terho Lehtimäki, Evangelos Andreakos, Marc Feldmann, Irina Udalova, Ignat Drozdov, Claudia Monaco
Publié dans: Nature Communications, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-021-27862-9

Serum Biomarkers in Carotid Artery Disease

Auteurs: Vassiliki I. Kigka, Vassiliki Potsika, Michalis Mantzaris, Vassilis Tsakanikas,Igor Koncar, and Dimitrios I. Fotiadis
Publié dans: Diagnostics Journal, Numéro 2021 Nov; 11(11): 2143, 2021, ISSN 2075-4418
Éditeur: MDPI
DOI: 10.3390/diagnostics11112143

Therapeutic strategies targeting inflammation and immunity in atherosclerosis: how to proceed?

Auteurs: Suzanne E. Engelen, Alice J. B. Robinson, Yasemin-Xiomara Zurke, Claudia Monaco
Publié dans: Nature Reviews Cardiology, 2022, Page(s) 522–542, ISSN 1759-5002
Éditeur: Nature Publishing Group
DOI: 10.1038/s41569-021-00668-4

Fatty liver is associated with blood pathways of inflammatory response, immune system activation and prothrombotic state in Young Finns Study

Auteurs: Tuukka Taipale, Ilkka Seppälä, Emma Raitoharju, Nina Mononen, Leo-Pekka Lyytikäinen, Thomas Illig, Melanie Waldenberger, Markus Juonala, Nina Hutri-Kähönen, Niku Oksala, Mika Kähönen, Olli Raitakari, Terho Lehtimäki
Publié dans: Scientific Reports, Numéro 8/1, 2018, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-018-28563-y

Computational Simulation of Carotid Artery: From Patient-Specific Images to Finite Element Analysis

Auteurs: Smiljana Djorovic, Igor Saveljic, Nenad Filipovic
Publié dans: Journal of the Serbian Society for Computational Mechanics, Numéro 13/1, 2019, Page(s) 120-129, ISSN 1820-6530
Éditeur: The Serbian Society for Computational Mechanics (SSCM)
DOI: 10.24874/jsscm.2019.13.01.08

Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation

Auteurs: Mokry M, Boltjes A, Slenders L, Bel-Bordes G, Cui K, Brouwer E, Mekke JM, Depuydt MAC, Timmerman N, Waissi F, Verwer MC, Turner AW, Khan MD, Hodonsky CJ, Benavente ED, Hartman RJG, van den Dungen NAM, Lansu N, Nagyova E, Prange KHM, Kovacic JC, Björkegren JLM, Pavlos E, Andreakos E, Schunkert H, Owens GK, Monaco C, Finn AV, Virmani R, Leeper NJ, de Winther MPJ, Kuiper J, de Borst GJ, Stroes ESG,
Publié dans: Nat Cardiovasc Res., 2022, ISSN 2731-0590
Éditeur: Springer Nature
DOI: 10.1038/s44161-022-00171-0

Meta-analysis of epigenome-wide association studies of carotid intima-media thickness

Auteurs: Portilla-Fernández E, Hwang SJ, Wilson R. et al
Publié dans: European J Epidemiol, 2021, ISSN 1573-7284
Éditeur: Springer
DOI: 10.1007/s10654-021-00759-z

Influence of genetic variation in PDE3A on endothelial function and stroke

Auteurs: Traylor , M., Amin Al Olama, A., Lyytikäinen, L. P., Marini, S., Chung, J., Malik, R., ... & Markus, H. S.
Publié dans: Hypertension, 2020, ISSN 1524-4563
Éditeur: Lippincott Williams & Wilkins
DOI: 10.1161/hypertensionaha.119.13513

Family history and polygenic risk of cardiovascular disease: independent factors associated with secondary cardiovascular events in patients undergoing carotid endarterectomy

Auteurs: Nathalie Timmerman; Dominique P.V. de Kleijn; Gert J. de Borst; Hester M. den Ruijter; Folkert W. Asselbergs; Folkert W. Asselbergs; Gerard Pasterkamp; S. Haitjema; Sander W. van der Laan
Publié dans: Atherosclerosis, 2020, ISSN 0021-9150
Éditeur: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2020.04.013

Assessment of plasma ceramides as predictor for subclinical atherosclerosis

Auteurs: Pashupati Mishra, Binisha Hamal Mishra, Leo-Pekka Lyytikäinen, Mika Hilvo, Markus Juonala, Mika Kähönen, Nina Hutri-Kähönen, Dimitrios I. Fotiadis, Olli T. Raitakari, Reijo Laaksonen, Terho Lehtimäki
Publié dans: Atherosclerosis Plus, 2021, ISSN 2667-0909
Éditeur: Elsevier
DOI: 10.1016/j.athplu.2021.09.005

Software that combines deep learning, 3D reconstruction and computational fluid dynamics to analyze state of carotid arteries from Ultrasound imaging

Auteurs: Smiljana Tomasevic, Milos Anic, Branko Arsic, Branko Gakovic, Nenad Filipovic, Tijana Djukic
Publié dans: Technology and Health Care, 2024, ISSN 1878-7401
Éditeur: IOS Press BV. H-Index
DOI: 10.5281/zenodo.10693578

Prosaposin mediates inflammation in atherosclerosis

Auteurs: Mandy M.T. van Leent, Thijs J. Beldman, Yohana C. Toner, Marnix A. Lameijer1, Nils Rother, Siroon Bekkering, Abraham J.P. Teunissen, Xianxiao Zhou, Roy van der Meel, Joost Malkus, Sheqouia A. Nauta, Emma D. Klein, Francois Fay, Brenda L. SanchezGaytan, Carlos Pérez-Medina, Ewelina Kluza, Yu-Xiang Ye, Gregory Wojtkiewicz, Edward A. Fisher, Filip K. Swirski, Matthias Nahrendorf, Bin Zhang,Lang Li,
Publié dans: Sci Transl Med, Numéro 2021 March 10; 13(584), 2021, Page(s) 1-28, ISSN 1946-6234
Éditeur: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abe1433

Agent Based and Finite Element Method for Plaque Development in the Carotid Artery

Auteurs: Nenad Filipovic, Andjela Blagojevic, Smiljana Tomasevic, Branko Arsic, Tijana Djukic
Publié dans: AORTA, 2022, ISSN 2325-4637
Éditeur: Thieme Medical Publishers, Inc.
DOI: 10.1055/s-0042-1750984

Efficient gene set analysis of high-throughput data. From omics to pathway architecture of health and disease

Auteurs: Pashupati P. Mishra
Publié dans: 2020
Éditeur: Unigrafia Oy

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