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Towards enduring mouse resources and services advancing research into human health and disease

Descripción del proyecto

Recursos sostenibles de modelos murinos para la investigación biomédica

Los modelos murinos son muy importantes en la investigación biomédica, ya que sirven como herramientas valiosas para estudiar enfermedades humanas, investigar funciones genéticas y probar posibles tratamientos. Sus breves ciclos reproductivos y su capacidad para ser manipulados genéticamente los convierten en un organismo modelo eficaz. El equipo del proyecto INFRAFRONTIER2020, financiado con fondos europeos, tiene como objetivo garantizar el acceso a modelos murinos mediante la ampliación de la red INFRAFRONTIER de infraestructuras de investigación, lo que facilitará la colaboración con la industria y los consorcios mundiales. Su equipo desarrollará modelos de negocio, un marco jurídico y servicios personalizados. Además concienciará para garantizar la sostenibilidad de la red a largo plazo.

Objetivo

The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society.

The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is strategically responding to the INFRADEV3 call with aligned objectives to advance the long-term sustainability which are 1) development of business models and a stable legal framework; 2) raise awareness of the INFRAFRONTIER RI; 3) provide bespoke services aligned with user demands; 4) promote best practices in mouse phenogenomics; 5) enhance robustness of the INFRAFRONTIER IT infrastructure and use of the EMMA strain resource; and 6) improve business processes. Towards achieving these objectives key INFRAFRONTIER2020 project deliverables are:

• INFRAFRONTIER Business Plan2.0 and business models for all services
• Stable legal framework built on the INFRAFRONTIER legal entity
• INFRAFRONTIER annual stakeholder conferences
• Customised mouse model and secondary phenotyping pilot services
• INFRAFRONTIER advanced training schools in mouse phenogenomics
• Reengineered EMMA Database2.0 system
• Annotated mouse models of human diseases
• Quality management system for the legal entity

INFRAFRONTIER2020 will 1) enhance the sustainable operation of the INFRAFRONTIER RI; 2) continue to structure the ERA, 3) foster innovation, and 4) address major societal challenges in human health by customised service pilots supporting research into common and rare diseases. A sustainable INFRAFRONTIER RI will ensure the quality of deposited mice and support the reproducibility of biological results. Outreach efforts will raise awareness of resources and services and facilitate sustainable engagement with industry and global consortia such as the International Mouse Phenotyping Consortium

Convocatoria de propuestas

H2020-INFRADEV-2016-2017

Consulte otros proyectos de esta convocatoria

Convocatoria de subcontratación

H2020-INFRADEV-2016-1

Régimen de financiación

CSA - Coordination and support action

Coordinador

INFRAFRONTIER GMBH
Aportación neta de la UEn
€ 1 713 235,00
Dirección
INGOLSTADTER LANDSTRASSE 1
85764 Neuherberg
Alemania

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Región
Bayern Oberbayern München, Landkreis
Tipo de actividad
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Enlaces
Coste total
€ 1 713 235,00

Participantes (28)