MIcrobiota-Gut-BraiN EngineeRed platform to eVAluate intestinal microflora impact on brain functionality

Project Information

MINERVA

Grant agreement ID: 724734

DOI 10.3030/724734

Project closed

EC signature date 13 March 2017

Start date 1 May 2017

End date 31 October 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 999 194,00

EU contribution € 1 999 194,00

Coordinated by

POLITECNICO DI MILANO
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (14)

The microbiota-gut-brain axis and epilepsy from a multidisciplinary perspective: Clinical evidenceand technological solutions for improvement of in vitro preclinical models

Author(s): Federica Fusco, Simone Perottoni, Carmen Giordano, Antonella Riva, Luigi Francesco Iannone, Carmen De Caro, Emilio Russo, Diego Albani, Pasquale Striano
Published in: Bioengineering & Translational medicine, 2022, Page(s) e10296, ISSN 2380-6761
Publisher: John Wiley & Sons, Inc.
DOI: 10.1002/btm2.10296

3D brain tissue physiological model with co-cultured primary neurons and glial cells in hydrogels

Author(s): Ilaria Raimondi, Marta Tunesi, Gianluigi Forloni, Diego Albani, Carmen Giordano
Published in: Journal of Tissue Engineering, Issue 11, 2020, Page(s) 204173142096398, ISSN 2041-7314
Publisher: SAGE Publisher
DOI: 10.1177/2041731420963981

MINERVA: The technological project to boost research on the microbiota-gut-brain axis in chronic neurodegenerative disorders

Author(s): Carmen Giordano, Diego Albani
Published in: AGRO FOOD INDUSTRY HI-TECH, Issue 28 (6), 2017, Page(s) 48-50, ISSN 1722-6996
Publisher: Teknoscienze s.r.l.

Influence of the static magnetic field on cell response in a miniaturized optically accessible bioreactor for 3D cell culture

Author(s): Luca Izzo, Marta Tunesi, Lucia Boeri, Matteo Laganà, Carmen Giordano, Manuela Teresa Raimondi
Published in: Biomedical Microdevices, Issue 21/1, 2019, ISSN 1387-2176
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10544-019-0387-8

An Organ-On-A-Chip Engineered Platform to Study the Microbiota–Gut–Brain Axis in Neurodegeneration

Author(s): Manuela Teresa Raimondi, Diego Albani, Carmen Giordano
Published in: Trends in Molecular Medicine, Issue 25/9, 2019, Page(s) 737-740, ISSN 1471-4914
Publisher: Elsevier BV
DOI: 10.1016/j.molmed.2019.07.006

Towards bioinspired in vitro models of intestinal mucus

Author(s): Lorenzo Sardelli, Daniela Peneda Pacheco, Anna Ziccarelli, Marta Tunesi, Omar Caspani, Andrea Fusari, Francesco Briatico Vangosa, Carmen Giordano, Paola Petrini
Published in: RSC Advances, Issue 9/28, 2019, Page(s) 15887-15899, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9ra02368b

Advanced Organ-on-a-Chip Devices to Investigate Liver Multi-Organ Communication: Focus on Gut, Microbiota and Brain

Author(s): Lucia Boeri, Luca Izzo, Lorenzo Sardelli, Marta Tunesi, Diego Albani, Carmen Giordano
Published in: Bioengineering, Issue 6/4, 2019, Page(s) 91, ISSN 2306-5354
Publisher: Basel : MDPI AG, 2014-
DOI: 10.3390/bioengineering6040091

CURRENT PERSPECTIVES ON THE MICROBIOTA-GUT-BRAIN AXIS IN CHRONIC NEURODEGENERATIVE DISORDERS

Author(s): Diego Albani, Carmen Giordano
Published in: Istituto Lombardo - Accademia di Scienze e Lettere - Rendiconti di Scienze, Issue 151, 2020, Page(s) 1-12, ISSN 2384-986X
Publisher: PAGEPress
DOI: 10.4081/scie.2017.641

Organ-On-A-Chip in vitro Models of the Brain and the Blood-Brain Barrier and Their Value to Study the Microbiota-Gut-Brain Axis in Neurodegeneration

Author(s): Ilaria Raimondi, Luca Izzo, Marta Tunesi, Manola Comar, Diego Albani, Carmen Giordano
Published in: Frontiers in Bioengineering and Biotechnology, Issue 7, 2020, Page(s) 1-17, ISSN 2296-4185
Publisher: Lausanne : Frontiers Editorial Office
DOI: 10.3389/fbioe.2019.00435

Human Gut-Microbiota Interaction in Neurodegenerative Disorders and Current Engineered Tools for Its Modeling

Author(s): Florencia Andrea Ceppa, Luca Izzo, Lorenzo Sardelli, Ilaria Raimondi, Marta Tunesi, Diego Albani, Carmen Giordano
Published in: Frontiers in Cellular and Infection Microbiology, Issue 10, 2020, Page(s) 1-18, ISSN 2235-2988
Publisher: Frontiers Media S. A.
DOI: 10.3389/fcimb.2020.00297

Microbiota‐Host Immunity Communication in Neurodegenerative Disorders: Bioengineering Challenges for In Vitro Modeling

Author(s): Lucia Boeri, Simone Perottoni, Luca Izzo, Carmen Giordano, Diego Albani
Published in: Advanced Healthcare Materials, Issue 2002043, 2021, Page(s) 1-17, ISSN 2192-2659
Publisher: World Scientific
DOI: 10.1002/adhm.202002043

Using integrated meta-omics to appreciate the role of the gut microbiota in epilepsy

Author(s): Lucia Boeri, Francesca Donnaloja, Marzia Campanile, Lorenzo Sardelli, Marta Tunesi, Federica Fusco, Carmen Giordano, Diego Albani
Published in: Neurobiology of Disease, Issue 164, 2022, Page(s) 105614, ISSN 0969-9961
Publisher: Academic Press
DOI: 10.1016/j.nbd.2022.105614

Technological tools and strategies for culturing human gut microbiota in engineered in vitro models

Author(s): Lorenzo Sardelli, Simone Perottoni, Marta Tunesi, Lucia Boeri, Federica Fusco, Paola Petrini, Diego Albani, Carmen Giordano
Published in: Biotechnology and Bioengineering, Issue 118/8, 2021, Page(s) 2886-2905, ISSN 0006-3592
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/bit.27816

A miniaturized hydrogel-based in vitro model for dynamic culturing of human cells overexpressing beta-amyloid precursor protein

Author(s): Marta Tunesi, Luca Izzo, Ilaria Raimondi, Diego Albani, Carmen Giordano
Published in: Journal of Tissue Engineering, Issue 11, 2020, Page(s) 204173142094563, ISSN 2041-7314
Publisher: SAGE Publisher
DOI: 10.1177/2041731420945633

Intellectual Property Rights

Patent (1)

MILLIFLUIDIC DEVICE FOR ADVANCED CULTURES OF BIOLOGICAL AGENTS

Application/Publication number: 20 20058339
Date: 2020-09-08