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International Network for Training on Risks of vascular Intimal Calcification And roads to Regression of cardiovascular diseasE

Livrables

Periodic report

Draft Periodic Report for the purpose of the meeting

INTRICARE special issue

INTRICARE special issue in Schattauer Thrombosis Haemostasis

Mid Term Report
Progress Report
Call for applicants

Call for applicants to be distributed via channels as described in Chapter 2.3. (M1)

Data Management Plan (DMP)

Data Management Plan DMP

Supervisory Board of the Network
MEC

Medical Ethical Committee protocols for human studies ESR10 ESR11

Publications

Bone mineral density at different sites and 5 years mortality in end-stage renal disease patients: A cohort study

Auteurs: Ken Iseri, Abdul Rashid Qureshi, Lu Dai, Jonaz Ripsweden, Olof Heimbürger, Peter Barany, Ingrid Bergström, Peter Stenvinkel, Torkel B. Brismar, Bengt Lindholm
Publié dans: Bone, Numéro 130, 2020, Page(s) 115075, ISSN 8756-3282
Éditeur: Elsevier BV
DOI: 10.1016/j.bone.2019.115075

Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality

Auteurs: S. K. Samal, A. R. Qureshi, M. Rahman, P. Stenvinkel, J. Frostegård
Publié dans: Clinical & Experimental Immunology, Numéro 201/1, 2020, Page(s) 94-104, ISSN 0009-9104
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/cei.13441

Magnetic resonance imaging of carotid plaques: current status and clinical perspectives

Auteurs: Mohamed Kassem, Alexandru Florea, Felix M. Mottaghy, Robert van Oostenbrugge, M. Eline Kooi
Publié dans: Annals of Translational Medicine, Numéro 8/19, 2020, Page(s) 1266-1266, ISSN 2305-5839
Éditeur: AME Publishing Company
DOI: 10.21037/atm-2020-cass-16

Early Vascular Ageing and Cellular Senescence in Chronic Kidney Disease

Auteurs: Lu Dai, Abdul Rashid Qureshi, Anna Witasp, Bengt Lindholm, Peter Stenvinkel
Publié dans: Computational and Structural Biotechnology Journal, Numéro 17, 2019, Page(s) 721-729, ISSN 2001-0370
Éditeur: Elsevier
DOI: 10.1016/j.csbj.2019.06.015

Cruciferous vegetables: rationale for exploring potential salutary effects of sulforaphane-rich foods in patients with chronic kidney disease

Auteurs: Ludmila F M F Cardozo, Livia A Alvarenga, Marcia Ribeiro, Lu Dai, Paul G Shiels, Peter Stenvinkel, Bengt Lindholm, Denise Mafra
Publié dans: Nutrition Reviews, 2020, ISSN 0029-6643
Éditeur: International Life Sciences Institute
DOI: 10.1093/nutrit/nuaa129

A biomimetic natural sciences approach to understanding the mechanisms of ageing in burden of lifestyle diseases

Auteurs: Lu Dai, Leon Schurgers, Paul G. Shiels, Peter Stenvinkel
Publié dans: Clinical Science, Numéro 135/10, 2021, Page(s) 1251-1272, ISSN 0143-5221
Éditeur: Portland Press, Ltd.
DOI: 10.1042/cs20201452

Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits

Auteurs: Marina A. Heuschkel, Nikolaos T. Skenteris, Joshua D. Hutcheson, Dewy D. van der Valk, Juliane Bremer, Philip Goody, Jesper Hjortnaes, Felix Jansen, Carlijn V.C. Bouten, Antoon van den Bogaerdt, Ljubica Matic, Nikolaus Marx, Claudia Goettsch
Publié dans: Cells, Numéro 9/10, 2020, Page(s) 2164, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9102164

Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks

Auteurs: Annemiek Dickhout, Rory R. Koenen
Publié dans: Frontiers in Cardiovascular Medicine, Numéro 5, 2018, ISSN 2297-055X
Éditeur: Lausanne: Frontiers Media S.A
DOI: 10.3389/fcvm.2018.00113

Antibodies against Malondialdehyde in Haemodialysis Patients and Its Association with Clinical Outcomes: Differences between Subclasses and Isotypes

Auteurs: Shailesh Kumar Samal, Abdul Rashid Qureshi, Mizanur Rahman, Peter Stenvinkel, Johan Frostegård
Publié dans: Journal of Clinical Medicine, 2020, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9030753

Decoding myofibroblast origins in human kidney fibrosis

Auteurs: Christoph Kuppe, Mahmoud M. Ibrahim, Jennifer Kranz, Xiaoting Zhang, Susanne Ziegler, Javier Perales-Patón, Jitske Jansen, Katharina C. Reimer, James R. Smith, Ross Dobie, John R. Wilson-Kanamori, Maurice Halder, Yaoxian Xu, Nazanin Kabgani, Nadine Kaesler, Martin Klaus, Lukas Gernhold, Victor G. Puelles, Tobias B. Huber, Peter Boor, Sylvia Menzel, Remco M. Hoogenboezem, Eric M. J. Bindels, Joach
Publié dans: Nature, Numéro 589/7841, 2021, Page(s) 281-286, ISSN 0028-0836
Éditeur: Nature Publishing Group
DOI: 10.1038/s41586-020-2941-1

Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification.

Auteurs: Martijn L. Chatrou; Diane Proudfoot; Guillaume J.J.M. van Eys; Brecht A. G. Willems; Leon J. Schurgers; Asim Cengiz Akbulut; Marie-Luce Bochaton-Piallat; Ljubica Perisic; Chris P. M. Reutelingsperger; Harald H.H.W. Schmidt; Barend Mees; C. Shanahan; Erik A.L. Biessen; Rick van Gorp; Malgorzata Furmanik; Ulf Hedin
Publié dans: Circulation Research, 2020, ISSN 0009-7330
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.119.316159

Skin autofluorescence, arterial stiffness and Framingham risk score as predictors of clinical outcome in chronic kidney disease patients: a cohort study

Auteurs: Hideyuki Mukai, Oskar Svedberg, Bengt Lindholm, Lu Dai, Olof Heimbürger, Peter Barany, Björn Anderstam, Peter Stenvinkel, Abdul Rashid Qureshi
Publié dans: Nephrology Dialysis Transplantation, Numéro 34/3, 2018, Page(s) 442-448, ISSN 0931-0509
Éditeur: Oxford University Press
DOI: 10.1093/ndt/gfx371

PET/MRI of atherosclerosis

Auteurs: Mueez Aizaz, Rik P. M. Moonen, Jochem A. J. van der Pol, Claudia Prieto, René M. Botnar, M. Eline Kooi
Publié dans: Cardiovascular Diagnosis and Therapy, Numéro 10/4, 2020, Page(s) 1120-1139, ISSN 2223-3652
Éditeur: AME Publishing Company
DOI: 10.21037/cdt.2020.02.09

Potential natural immunization against atherosclerosis in hibernating bears

Auteurs: Shailesh Kumar Samal, Ole Fröbert, Jonas Kindberg, Peter Stenvinkel, Johan Frostegård
Publié dans: Scientific Reports, Numéro 11/1, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-91679-1

No Association between Thrombin Generation and Intra-Plaque Haemorrhage in Symptomatic Carotid Atherosclerotic Plaques: The Plaque at RISK (PARISK) Study

Auteurs: Geneviève Crombag, Henri Spronk, Patty Nelemans, Floris Schreuder, Martine Truijman, Anouk van Dijk, Alexandra de Rotte, Madieke Liem, Mat Daemen, Anton van der Steen, Werner Mess, Paul Nederkoorn, Jeroen Hendrikse, Aad van der Lugt, Joachim Wildberger, Hugo ten Cate, Robert van Oostenbrugge, M. Kooi
Publié dans: Thrombosis and Haemostasis, Numéro 118/08, 2018, Page(s) 1461-1469, ISSN 0340-6245
Éditeur: Schattauer
DOI: 10.1055/s-0038-1666858

Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease

Auteurs: Tove Fall; Darren Green; Abdul Rashid Qureshi; Peter Stenvinkel; Axel C. Carlsson; Axel C. Carlsson; Peter Bárány; Tobias Feldreich; Tobias Feldreich; Tobias Feldreich; Juan Jesus Carrero; Olof Heimbürger; Jonas Ripsweden; Christoph Nowak; Philip A. Kalra; Nicolas Vuilleumier; Johan Ärnlöv
Publié dans: Journal of Nephrology, 2018, ISSN 1120-3625
Éditeur: Springer
DOI: 10.1007/s40620-018-0556-5

Resolution of Inflammation Through the Lipoxin and ALX/FPR2 Receptor Pathway Protects Against Abdominal Aortic Aneurysms

Auteurs: Marcelo H. Petri, Silke Thul, Teodora Andonova, Moritz Lindquist-Liljeqvist, Hong Jin, Nikolaos-Taxiarchis Skenteris, Hildur Arnardottir, Lars Maegdefessel, Kenneth Caidahl, Mauro Perretti, Joy Roy, Magnus Bäck
Publié dans: JACC: Basic to Translational Science, Numéro 3/6, 2018, Page(s) 719-727, ISSN 2452-302X
Éditeur: Elsevier
DOI: 10.1016/j.jacbts.2018.08.005

Cranberries – potential benefits in patients with chronic kidney disease

Auteurs: Livia de Almeida Alvarenga, Natália Alvarenga Borges, Laís de Souza Gouveia Moreira, Karla Thaís Resende Teixeira, José Carlos Carraro-Eduardo, Lu Dai, Peter Stenvinkel, Bengt Lindholm, Denise Mafra
Publié dans: Food & Function, Numéro 10/6, 2019, Page(s) 3103-3112, ISSN 2042-650X
Éditeur: Royal Society of Chemistry
DOI: 10.1039/c9fo00375d

Phenotypic features of vascular calcification in chronic kidney disease

Auteurs: L. Dai, M. Debowska, T. Lukaszuk, L. Bobrowski, P. Barany, M. Söderberg, D. Thiagarajan, J. Frostegård, L. Wennberg, B. Lindholm, A. R. Qureshi, J. Waniewski, P. Stenvinkel
Publié dans: Journal of Internal Medicine, Numéro 287/4, 2020, Page(s) 422-434, ISSN 0954-6820
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/joim.13012

Vitamin K2 Needs an RDI Separate from Vitamin K1

Auteurs: Asim Cengiz Akbulut, Angelina Pavlic, Ploingarm Petsophonsakul, Maurice Halder, Katarzyna Maresz, Rafael Kramann, Leon Schurgers
Publié dans: Nutrients, Numéro 12/6, 2020, Page(s) 1852, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu12061852

Aortic Valve Calcium Associates with All-Cause Mortality Independent of Coronary Artery Calcium and Inflammation in Patients with End-Stage Renal Disease

Auteurs: Lu Dai, Oscar Plunde, Abdul Rashid Qureshi, Bengt Lindholm, Torkel B. Brismar, Leon J. Schurgers, Magnus Söderberg, Jonaz Ripsweden, Magnus Bäck, Peter Stenvinkel
Publié dans: Journal of Clinical Medicine, Numéro 9/2, 2020, Page(s) 607, ISSN 2077-0383
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9020607

The Interplay of WNT and PPARγ Signaling in Vascular Calcification

Auteurs: Stefan Reinhold, W. Matthijs Blankesteijn, Sébastien Foulquier
Publié dans: Cells, Numéro 9/12, 2020, Page(s) 2658, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9122658

Sodium [18F]Fluoride PET Can Efficiently Monitor In Vivo Atherosclerotic Plaque Calcification Progression and Treatment

Auteurs: Alexandru Florea, Julius P. Sigl, Agnieszka Morgenroth, Andreas Vogg, Sabri Sahnoun, Oliver H. Winz, Jan Bucerius, Leon J. Schurgers, Felix M. Mottaghy
Publié dans: Cells, Numéro 10/2, 2021, Page(s) 275, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells10020275

Development, establishment and validation of in vitro and ex vivo assays of vascular calcification

Auteurs: Joachim Jankowski; Joachim Jankowski; Michael Böhm; Setareh Orth-Alampour; Jana Holmar; Heidi Noels; Shruti Bhargava
Publié dans: Biochemical and Biophysical Research Communications, 2020, Page(s) 462-470, ISSN 0006-291X
Éditeur: Academic Press
DOI: 10.1016/j.bbrc.2020.05.085

Serum 8-hydroxydeoxyguanosine, a marker of oxidative DNA damage, is associated with mortality independent of inflammation in chronic kidney disease

Auteurs: Lu Dai, Makoto Watanabe, Abdul Rashid Qureshi, Hideyuki Mukai, Anna Machowska, Olof Heimbürger, Peter Barany, Bengt Lindholm, Peter Stenvinkel
Publié dans: European Journal of Internal Medicine, Numéro 68, 2019, Page(s) 60-65, ISSN 0953-6205
Éditeur: Elsevier BV
DOI: 10.1016/j.ejim.2019.07.035

HER2-directed antibodies, affibodies and nanobodies as drug-delivery vehicles in breast cancer with a specific focus on radioimmunotherapy and radioimmunoimaging

Auteurs: Betül Altunay, Agnieszka Morgenroth, Mohsen Beheshti, Andreas Vogg, Nicholas C. L. Wong, Hong Hoi Ting, Hans-Jürgen Biersack, Elmar Stickeler, Felix M. Mottaghy
Publié dans: European Journal of Nuclear Medicine and Molecular Imaging, Numéro 48/5, 2021, Page(s) 1371-1389, ISSN 1619-7070
Éditeur: Springer Verlag
DOI: 10.1007/s00259-020-05094-1

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

Auteurs: Till Seime, Asim Cengiz Akbulut, Moritz Lindquist Liljeqvist, Antti Siika, Hong Jin, Greg Winski, Rick H. van Gorp, Eva Karlöf, Mariette Lengquist, Andrew J. Buckler, Malin Kronqvist, Olivia J. Waring, Jan H. N. Lindeman, Erik A. L. Biessen, Lars Maegdefessel, Anton Razuvaev, Leon J. Schurgers, Ulf Hedin, Ljubica Matic
Publié dans: Cells, Numéro 10/6, 2021, Page(s) 1276, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells10061276

Locking and loading the bullet against micro-calcification

Auteurs: Alexandru Florea, Agnieszka Morgenroth, Jan Bucerius, Leon J Schurgers, Felix M Mottaghy
Publié dans: European Journal of Preventive Cardiology, 2020, Page(s) 204748732091113, ISSN 2047-4873
Éditeur: SAGE Publications Ltd
DOI: 10.1177/2047487320911138

Microvasculature and intraplaque hemorrhage in atherosclerotic carotid lesions: a cardiovascular magnetic resonance imaging study.

Auteurs: Martine T. B. Truijman; Werner H. Mess; Sylvia Heeneman; Robert J. van Oostenbrugge; Patty J. Nelemans; Floris H.B.M. Schreuder; Jan-Willem H.C. Daemen; Raf H. M. van Hoof; Raf H. M. van Hoof; Paul J. Nederkoorn; Stefan Vöö; Stefan Vöö; Mat J.A.P. Daemen; Geneviève A. J. C. Crombag; Geneviève A. J. C. Crombag; M. Eline Kooi; M. Eline Kooi; Joachim E. Wildberger; Joachim E. Wildberger; Nicky
Publié dans: Journal of Cardiovascular Magnetic Resonance, 2019, ISSN 1097-6647
Éditeur: BioMed Central
DOI: 10.1186/s12968-019-0524-9

The Bone-Vasculature Axis: Calcium Supplementation and the Role of Vitamin K.

Auteurs: Grzegorz B. Wasilewski; Grzegorz B. Wasilewski; Marc G. Vervloet; Leon J. Schurgers
Publié dans: Frontiers in Cardiovascular Medicine, 2019, ISSN 2297-055X
Éditeur: Lausanne: Frontiers Media S.A.
DOI: 10.3389/fcvm.2019.00006

Functional vitamin K insufficiency, vascular calcification and mortality in advanced chronic kidney disease: A cohort study

Auteurs: Lu Dai, Longkai Li, Helen Erlandsson, Armand M. G. Jaminon, Abdul Rashid Qureshi, Jonaz Ripsweden, Torkel B. Brismar, Anna Witasp, Olof Heimbürger, Hanne Skou Jørgensen, Peter Barany, Bengt Lindholm, Pieter Evenepoel, Leon J. Schurgers, Peter Stenvinkel
Publié dans: PLOS ONE, Numéro 16/2, 2021, Page(s) e0247623, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0247623

Association between fibrinogen and fibrinogen γ’ and atherosclerotic plaque morphology and composition in symptomatic carotid artery stenosis: Plaque-At-RISK study

Auteurs: A.C. van Dijk, S.J. Donkel, T. Zadi, M.A.H. Sonneveld, F.H.B.M. Schreuder, M.F. Chohan, P.J. Koudstaal, F.W.G. Leebeek, R. Saxena, J. Hendrikse, M.E. Kooi, A. van der Lugt, M.P.M. de Maat
Publié dans: Thrombosis Research, Numéro 177, 2019, Page(s) 130-135, ISSN 0049-3848
Éditeur: Pergamon Press
DOI: 10.1016/j.thromres.2019.02.030

Matrix Gla protein is an independent predictor of both intimal and medial vascular calcification in chronic kidney disease

Auteurs: Armand M. G. Jaminon, Lu Dai, Abdul Rashid Qureshi, Pieter Evenepoel, Jonaz Ripsweden, Magnus Söderberg, Anna Witasp, Hannes Olauson, Leon J. Schurgers, Peter Stenvinkel
Publié dans: Scientific Reports, Numéro 10/1, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-63013-8

Initiation and Propagation of Vascular Calcification Is Regulated by a Concert of Platelet- and Smooth Muscle Cell-Derived Extracellular Vesicles

Auteurs: Leon J. Schurgers, Asim C. Akbulut, Dawid M. Kaczor, Maurice Halder, Rory R. Koenen, Rafael Kramann
Publié dans: Frontiers in Cardiovascular Medicine, Numéro 5, 2018, ISSN 2297-055X
Éditeur: Frontiers in Cardiovascular Medicine
DOI: 10.3389/fcvm.2018.00036

Target identification for the diagnosis and intervention of vulnerable atherosclerotic plaques beyond 18F-fluorodeoxyglucose positron emission tomography imaging: promising tracers on the horizon

Auteurs: Jan Bucerius, Ingrid Dijkgraaf, Felix M. Mottaghy, Leon J. Schurgers
Publié dans: European Journal of Nuclear Medicine and Molecular Imaging, Numéro 46/1, 2019, Page(s) 251-265, ISSN 1619-7070
Éditeur: Springer Verlag
DOI: 10.1007/s00259-018-4176-z

Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease

Auteurs: Maurice Halder, Ploingarm Petsophonsakul, Asim Akbulut, Angelina Pavlic, Frode Bohan, Eric Anderson, Katarzyna Maresz, Rafael Kramann, Leon Schurgers
Publié dans: International Journal of Molecular Sciences, Numéro 20/4, 2019, Page(s) 896, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20040896

Inverse J-shaped relation between coronary arterial calcium density and mortality in advanced chronic kidney disease

Auteurs: Hideyuki Mukai, Lu Dai, Zhimin Chen, Bengt Lindholm, Jonaz Ripsweden, Torkel B Brismar, Olof Heimbürger, Peter Barany, Abdul Rashid Qureshi, Magnus Söderberg, Magnus Bäck, Peter Stenvinkel
Publié dans: Nephrology Dialysis Transplantation, 2018, ISSN 0931-0509
Éditeur: Oxford University Press
DOI: 10.1093/ndt/gfy352

Wnt/β-Catenin Inhibitor Dickkopf 1

Auteurs: Stefan Reinhold, W. Matthijs Blankesteijn
Publié dans: Arteriosclerosis, Thrombosis, and Vascular Biology, Numéro 39/2, 2019, Page(s) 121-123, ISSN 1079-5642
Éditeur: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/atvbaha.118.312144

Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization

Auteurs: Eva Karlöf, Till Seime, Nuno Dias, Mariette Lengquist, Anna Witasp, Håkan Almqvist, Malin Kronqvist, Jesper R. Gådin, Jacob Odeberg, Lars Maegdefessel, Peter Stenvinkel, Ljubica Perisic Matic, Ulf Hedin
Publié dans: Atherosclerosis, 2019, ISSN 0021-9150
Éditeur: Elsevier BV
DOI: 10.1016/j.atherosclerosis.2019.05.005

Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification

Auteurs: Gonzalo Artiach, Miguel Carracedo, Till Seime, Oscar Plunde, Andres Laguna-Fernandez, Ljubica Matic, Anders Franco-Cereceda, Magnus Bäck
Publié dans: Cells, Numéro 9/3, 2020, Page(s) 684, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9030684

Effects of Combined Vitamin K2 and Vitamin D3 Supplementation on Na[18F]F PET/MRI in Patients with Carotid Artery Disease: The INTRICATE Rationale and Trial Design

Auteurs: Alexandru Florea, M. Eline Kooi, Werner Mess, Leon J. Schurgers, Jan Bucerius, Felix M. Mottaghy
Publié dans: Nutrients, Numéro 13/3, 2021, Page(s) 994, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13030994

The role of receptor MAS in microglia-driven retinal vascular development

Auteurs: S. Foulquier, V. Caolo, G. Swennen, I. Milanova, S. Reinhold, C. Recarti, N. Alenina, M. Bader, U. M. Steckelings, T. Vanmierlo, M. J. Post, E. A. Jones, R. J. van Oostenbrugge, T. Unger
Publié dans: Angiogenesis, Numéro 22/4, 2019, Page(s) 481-489, ISSN 0969-6970
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10456-019-09671-3

Symptomatic Carotid Plaques Demonstrate Less Leaky Plaque Microvasculature Compared With the Contralateral Side: A Dynamic Contrast‐Enhanced Magnetic Resonance Imaging Study

Auteurs: Crombag, G.; Hoof, R.H.M. van; Holtackers, R.J.; Schreuder, F.H.B.M.; Truijman, M.T.; Schreuder, T.; Orshoven, N.P. Van; Mess, W.H.; Hofman, Paul A.M.; Oostenbrugge, R.J. van; Wildberger, J.E.; Kooi, M.Eline
Publié dans: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Numéro Bimonthly, 2019, ISSN 2047-9980
Éditeur: Wiley-Blackwell
DOI: 10.1161/jaha.118.011832

Early vascular ageing in chronic kidney disease: impact of inflammation, vitamin K, senescence and genomic damage

Auteurs: Lu Dai, Leon J Schurgers, Paul G Shiels, Peter Stenvinkel
Publié dans: Nephrology Dialysis Transplantation, Numéro 35/Supplement_2, 2020, Page(s) ii31-ii37, ISSN 0931-0509
Éditeur: Oxford University Press
DOI: 10.1093/ndt/gfaa006

Role of Uremic Toxins in Early Vascular Ageing and Calcification

Auteurs: Nikolaos C. Kyriakidis, Gabriela Cobo, Lu Dai, Bengt Lindholm, Peter Stenvinkel
Publié dans: Toxins, Numéro 13/1, 2021, Page(s) 26, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins13010026

Association between Biomarkers of Mineral and Bone Metabolism and Removal of Calcium and Phosphate in Hemodialysis

Auteurs: Malgorzata Debowska, Lu Dai, Alicja Wojcik-Zaluska, Jan Poleszczuk, Wojciech Zaluska, Bengt Lindholm, Jacek Waniewski
Publié dans: Blood Purification, Numéro 49/1-2, 2020, Page(s) 71-78, ISSN 0253-5068
Éditeur: S. Karger AG
DOI: 10.1159/000503623

Molecular Imaging of Angiogenesis in Oncology: Current Preclinical and Clinical Status

Auteurs: Alexandru Florea, Felix M. Mottaghy, Matthias Bauwens
Publié dans: International Journal of Molecular Sciences, Numéro 22/11, 2021, Page(s) 5544, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22115544

Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice

Auteurs: Samuel Röhl, Bianca E. Suur, Mariette Lengquist, Till Seime, Kenneth Caidahl, Ulf Hedin, Anders Arner, Ljubica Matic, Anton Razuvaev
Publié dans: Cells, Numéro 9/4, 2020, Page(s) 1009, ISSN 2073-4409
Éditeur: MDPI
DOI: 10.3390/cells9041009

Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug-Bug Interaction?

Auteurs: Abdul Rashid Qureshi; Peter Stenvinkel; Lu Dai; Henriette de Loor; Pieter Evenepoel; Leon J. Schurgers; Björn Meijers; Bert Bammens
Publié dans: Toxins, Vol 12, Iss 351, p 351 (2020), 2020, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins12060351

Serum concentration and vascular expression of adiponectin are differentially associated with the diabetic calcifying peripheral arteriopathy.

Auteurs: Franck Phan; Carole E. Aubert; Ljubica Perisic Matic; Christian Funck-Brentano; Agnès Hartemann; Peter Stenvinkel; M. Halbron; S. Kemel; Anna Witasp; Aurélie Carlier; Chloe Amouyal; Ziad A. Massy; Olivier Bourron; Jean-Marc Lacorte; Joe-Elie Salem; F. Lajat-Kiss; Sophie Liabeuf
Publié dans: Diabetology & Metabolic Syndrome, 2019, ISSN 1758-5996
Éditeur: BioMed Central
DOI: 10.1186/s13098-019-0429-7

The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes.

Auteurs: Jaminon, Armand; Reesink, Koen; Kroon, Abraham; Schurgers, Leon
Publié dans: International Journal of Molecular Sciences, 2019, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms20225694

Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells

Auteurs: Annemiek Dickhout, Dawid M. Kaczor, Alexandra C. A. Heinzmann, Sanne L. N. Brouns, Johan W. M. Heemskerk, Marc A. M. J. van Zandvoort, Rory R. Koenen
Publié dans: International Journal of Molecular Sciences, Numéro 22/14, 2021, Page(s) 7332, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22147332

Bone mineral density and mortality in end-stage renal disease patients

Auteurs: Ken Iseri, Lu Dai, Zhimin Chen, Abdul Rashid Qureshi, Torkel B Brismar, Peter Stenvinkel, Bengt Lindholm
Publié dans: Clinical Kidney Journal, Numéro 13/3, 2020, Page(s) 307-321, ISSN 2048-8505
Éditeur: Oxford University Press
DOI: 10.1093/ckj/sfaa089

The higher mortality associated with low serum albumin is dependent on systemic inflammation in end-stage kidney disease

Auteurs: Filipa Caeiro Alves, Jia Sun, Abdul Rashid Qureshi, Lu Dai, Sunna Snaedal, Peter Bárány, Olof Heimbürger, Bengt Lindholm, Peter Stenvinkel
Publié dans: PLOS ONE, Numéro 13/1, 2018, Page(s) e0190410, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0190410

Editorial: Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases

Auteurs: Rory R. Koenen, Elena Aikawa
Publié dans: Frontiers in Cardiovascular Medicine, Numéro 5, 2018, ISSN 2297-055X
Éditeur: Lausanne: Frontiers Media S.A
DOI: 10.3389/fcvm.2018.00133

Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response

Auteurs: Samuel Röhl, Urszula Rykaczewska, Till Seime, Bianca E. Suur, Maria Gonzalez Diez, Jesper R. Gådin, Anastasiia Gainullina, Alexey A. Sergushichev, Robert Wirka, Mariette Lengquist, Malin Kronqvist, Otto Bergman, Jacob Odeberg, Jan H.N. Lindeman, Thomas Quertermous, Anders Hamsten, Per Eriksson, Ulf Hedin, Anton Razuvaev, Ljubica Perisic Matic
Publié dans: JVS: Vascular Science, Numéro 1, 2020, Page(s) 13-27, ISSN 2666-3503
Éditeur: Elsevier
DOI: 10.1016/j.jvssci.2020.01.001

Menaquinone-7 Supplementation Improves Osteogenesis in Pluripotent Stem Cell Derived Mesenchymal Stem Cells

Auteurs: Asim Cengiz Akbulut, Grzegorz B. Wasilewski, Nikolas Rapp, Francesco Forin, Heike Singer, Katrin J. Czogalla-Nitsche, Leon J. Schurgers
Publié dans: Frontiers in Cell and Developmental Biology, Numéro 8, 2021, ISSN 2296-634X
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.618760

Copeptin is independently associated with vascular calcification in chronic kidney disease stage 5

Auteurs: Edyta Golembiewska, Abdul Rashid Qureshi, Lu Dai, Bengt Lindholm, Olof Heimbürger, Magnus Söderberg, Torkel B. Brismar, Jonaz Ripsweden, Peter Barany, Richard J. Johnson, Peter Stenvinkel
Publié dans: BMC Nephrology, Numéro 21/1, 2020, ISSN 1471-2369
Éditeur: BioMed Central
DOI: 10.1186/s12882-020-1710-6

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