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Host switching pathogens, infectious outbreaks and zoonosis; a Marie Sklodowska-Curie Training Network

Description du projet

Se préparer aux infections zoonotiques

Ces dernières années ont enregistré une augmentation de la transmission d’agents pathogènes de l’animal à l’homme, un phénomène connu sous le nom de zoonose. Le commerce mondial, le changement climatique et les vecteurs de maladies tels que les moustiques ont exacerbé ce phénomène, qui exige de meilleures mesures de préparation. Financé par le programme Actions Marie Skłodowska-Curie, le projet HONOURs entend répondre à cette menace mondiale en formant des chercheurs de diverses disciplines à la lutte contre les infections zoonotiques et à l’amélioration de la préparation. Ces stratégies, dont la détection et l’identification précoces des virus, le dépistage des animaux et des humains en contact avec ceux-ci et l’évaluation du potentiel pathogène des nouveaux virus, peuvent collectivement réduire le risque humain de contracter des maladies transmises par les animaux.

Objectif

The ongoing increase of the human population accompanied by growing numbers of livestock to feed this population, as well as human invasion into natural habitats of wild animals makes humans progressively vulnerable to animal pathogens. Global trade as well as climate changes can contribute to pathogen transmission, e.g. through import of infected vectors or expansion of habitats for arthropod vectors such as mosquitoes and midges. Examples for this include recent European outbreaks of the arthropod-borne Dengue, West Nile, Schmallenberg and Usutu viruses in humans, ruminants and birds. Infectious disease outbreaks in animals are often unexpected, but we should be prepared for immediate identification of the causing agent and the evaluation of its pathogenic potential for animals and humans. Preparedness needs expertise in many areas. At surveillance sites early detection and identification of viruses involved in outbreaks is crucial. Screening of different animal species and humans who have been in close contact with (diseased) animals for known or yet undiscovered viruses will also help to be prepared for future outbreaks. Novel viruses in these populations will have to be evaluated for their pathogenicity in susceptibility studies. The HONOURs network will generate new health and scientific knowledge with the aim to locate, identify, characterize, contain, and control infections that are caused by zoonotic agents. The aim of HONOURs is to provide top-quality cross-disciplinary and supra-sectorial training to 15 promising young researchers at the interface of veterinary and human health, virology, biostatistics, and pathogen discovery. These early stage researchers will become “preparedness- experts”.

Coordinateur

AMSTERDAM UMC RESEARCH BV
Contribution nette de l'UE
€ 510 748,56
Adresse
MEIBERGDREEF 9
1105 AZ AMSTERDAM
Pays-Bas

Voir sur la carte

Région
West-Nederland Noord-Holland Groot-Amsterdam
Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Liens
Coût total
€ 510 748,56

Participants (12)