Mechanism of DNA-protein cross-link repair in S phase

Project Information

DPC_REPAIR

Grant agreement ID: 715975

DOI 10.3030/715975

Project closed

EC signature date 30 October 2016

Start date 1 January 2017

End date 30 June 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 498 856,00

EU contribution € 1 498 856,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

Publications

Peer reviewed articles (7)

SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

Author(s): Lisa Schubert; Ivo A Hendriks; Emil P T Hertz; Wei Wu; Selene Sellés‐Baiget; Saskia Hoffmann; Keerthana Stine Viswalingam; Irene Gallina; Satyakrishna Pentakota; Bente Benedict; Joachim Johansen; Katja Apelt; Martijn S Luijsterburg; Simon Rasmussen; Michael Lisby; Ying Liu; Michael L Nielsen; Niels Mailand; Julien P Duxin
Published in: EMBO Reports, Issue 1469221X, 2022, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.202153639

Mechanism and function of DNA replication‐independent DNA‐protein crosslink repair via the SUMO‐RNF4 pathway

Author(s): Julio C Y Liu; Ulrike Kühbacher; Nicolai B. Larsen; Nikoline Borgermann; Dimitriya H Garvanska; Ivo A. Hendriks; Leena Ackermann; Peter Haahr; Irene Gallina; Claire Guérillon; Emma Branigan; Ronald T. Hay; Yoshiaki Azuma; Michael L. Nielsen; Julien P. Duxin; Niels Mailand
Published in: The EMBO Journal, Issue 02614189, 2021, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2020107413

How to fix DNA-protein crosslinks

Author(s): Ulrike Kühbacher and Julien P Duxin
Published in: DNA repair, Issue 15687864, 2020, ISSN 1568-7864
Publisher: Elsevier BV
DOI: 10.1016/j.dnarep.2020.102924

The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

Author(s): Irene Gallina; Ivo A.Hendriks; Saskia Hoffmann; Nicolai B.Larsen; Joachim Johansen; Camilla S.Colding-Christensen; Lisa Schubert; Selene Sellés-Baiget; Zita Fábián; Ulrike Kühbacher; Alan O.Gao; Markus Räschle; Simon Rasmussen; Michael L.Nielsen; Niels Mailand; Julien P.Duxin
Published in: Molecular Cell, Issue 10972765, 2021, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.11.029

Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts

Author(s): Nicolai B. Larsen, Alan O. Gao, Justin L. Sparks, Irene Gallina, R. Alex Wu, Matthias Mann, Markus Räschle, Johannes C. Walter, Julien P. Duxin
Published in: Molecular Cell, Issue 73/3, 2019, Page(s) 574-588.e7, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.11.024

Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model

Author(s): Hazal B. Kose, Nicolai B. Larsen, Julien P. Duxin, Hasan Yardimci
Published in: Cell Reports, Issue 26/8, 2019, Page(s) 2113-2125.e6, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.01.086

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

Author(s): Justin L. Sparks, Gheorghe Chistol, Alan O. Gao, Markus Räschle, Nicolai B. Larsen, Matthias Mann, Julien P. Duxin, Johannes C. Walter
Published in: Cell, Issue 176/1-2, 2019, Page(s) 167-181.e21, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2018.10.053