Mechanism of DNA-protein cross-link repair in S phase

Project Information

DPC_REPAIR

Grant agreement ID: 715975

DOI 10.3030/715975

Project closed

EC signature date 30 October 2016

Start date 1 January 2017

End date 30 June 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 498 856,00

EU contribution € 1 498 856,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

Author(s): Lisa Schubert; Ivo A Hendriks; Emil P T Hertz; Wei Wu; Selene Sellés‐Baiget; Saskia Hoffmann; Keerthana Stine Viswalingam; Irene Gallina; Satyakrishna Pentakota; Bente Benedict; Joachim Johansen; Katja Apelt; Martijn S Luijsterburg; Simon Rasmussen; Michael Lisby; Ying Liu; Michael L Nielsen; Niels Mailand; Julien P Duxin
Published in: EMBO Reports, Issue 1469221X, 2022, ISSN 1469-221X
Publisher: Nature Publishing Group
DOI: 10.15252/embr.202153639

Mechanism and function of DNA replication‐independent DNA‐protein crosslink repair via the SUMO‐RNF4 pathway

Author(s): Julio C Y Liu; Ulrike Kühbacher; Nicolai B. Larsen; Nikoline Borgermann; Dimitriya H Garvanska; Ivo A. Hendriks; Leena Ackermann; Peter Haahr; Irene Gallina; Claire Guérillon; Emma Branigan; Ronald T. Hay; Yoshiaki Azuma; Michael L. Nielsen; Julien P. Duxin; Niels Mailand
Published in: The EMBO Journal, Issue 02614189, 2021, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2020107413

How to fix DNA-protein crosslinks

Author(s): Ulrike Kühbacher and Julien P Duxin
Published in: DNA repair, Issue 15687864, 2020, ISSN 1568-7864
Publisher: Elsevier BV
DOI: 10.1016/j.dnarep.2020.102924

The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

Author(s): Irene Gallina; Ivo A.Hendriks; Saskia Hoffmann; Nicolai B.Larsen; Joachim Johansen; Camilla S.Colding-Christensen; Lisa Schubert; Selene Sellés-Baiget; Zita Fábián; Ulrike Kühbacher; Alan O.Gao; Markus Räschle; Simon Rasmussen; Michael L.Nielsen; Niels Mailand; Julien P.Duxin
Published in: Molecular Cell, Issue 10972765, 2021, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.11.029

Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts

Author(s): Nicolai B. Larsen, Alan O. Gao, Justin L. Sparks, Irene Gallina, R. Alex Wu, Matthias Mann, Markus Räschle, Johannes C. Walter, Julien P. Duxin
Published in: Molecular Cell, Issue 73/3, 2019, Page(s) 574-588.e7, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.11.024

Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model

Author(s): Hazal B. Kose, Nicolai B. Larsen, Julien P. Duxin, Hasan Yardimci
Published in: Cell Reports, Issue 26/8, 2019, Page(s) 2113-2125.e6, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2019.01.086

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

Author(s): Justin L. Sparks, Gheorghe Chistol, Alan O. Gao, Markus Räschle, Nicolai B. Larsen, Matthias Mann, Julien P. Duxin, Johannes C. Walter
Published in: Cell, Issue 176/1-2, 2019, Page(s) 167-181.e21, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2018.10.053