Objectif
Coronary Artery Disease (CAD) is the most common form of heart disease and is the leading cause of death in Europe and
the Western World. Positron Emission Tomography (PET) Myocardial Perfusion Imaging (MPI) offers the unique possibility
of measuring and quantifying myocardial blood flow and coronary flow reserve in absolute terms, which serve as a
prognostic marker for adverse cardiac events: It can predict the risk of heart attack. PET also offers advantages such as:
superior image quality and diagnostic ability, reduction of unnecessary invasive downstream procedures and reduction of
patients’ risks due to reduced radiation doses and shorter period of radiation retention. Currently, there is a shortage of
available, simple and efficient PET myocardial perfusion imaging agents. Motivated by the growing business opportunity in
PET cardiac imaging and the success of completed synthesis and evaluation discovery process, as well as pre-clinical trials
and toxicity tests, the objective of this project is Phase 1 and 2 clinical trials of the novel biomarker [11C]-DMDPA for
Myocardial Perfusion Imaging using Positron Emission Tomography, and to commercialize it globally. The adoption of
Positron Emission Tomography for Myocardial Perfusion Imaging will occur as a result of numerous advantages and the
growing abundance and availability of PET scanners in recent and future years. There is compelling evidence that our novel
biomarker is addressing a high growth trend in a high volume market of the cardiovascular disease nuclear imaging, and
specifically the growing need of non-invasive PET cardiac probes. According to publications, the projected growth rates
indicate that PET will outnumber SPECT cardiac procedures by 2020. The willingness to pay has been confirmed during our
economic feasibility assessment of the project, by means of consultancy with key stakeholders and negotiations with a
number of key players on Diagnostic Partnering deals.
Champ scientifique (EuroSciVoc)
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN.
CORDIS classe les projets avec EuroSciVoc, une taxonomie multilingue des domaines scientifiques, grâce à un processus semi-automatique basé sur des techniques TLN.
- sciences socialessociologiedémographiemortalité
- sciences médicales et de la santémédecine cliniquecardiologiemaladies cardiovasculaires
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SME-2 - SME instrument phase 2Coordinateur
00-710 WARSZAWA
Pologne
L’entreprise s’est définie comme une PME (petite et moyenne entreprise) au moment de la signature de la convention de subvention.