Tracking the Dynamics of Human Metabolism using Spectroscopy-Integrated Liver-on-Chip Microdevices

Project Information

OCLD

Grant agreement ID: 681870

DOI 10.3030/681870

Project closed

EC signature date 7 July 2016

Start date 1 October 2016

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 118 175,00

EU contribution € 2 118 175,00

Coordinated by

THE HEBREW UNIVERSITY OF JERUSALEM
Israel

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Circadian Effects of Drug Responses

Author(s): Yaakov Nahmias, Ioannis P. Androulakis
Published in: Annual Review of Biomedical Engineering, 2021, ISSN 1523-9829
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-bioeng-082120-034725

Mechanism and reversal of drug-induced nephrotoxicity on a chip

Author(s): Aaron Cohen, Konstantinos Ioannidis, Avner Ehrlich, Shaun Regenbaum, Merav Cohen, Muneef Ayyash, Sigal Shafran Tikva, Yaakov Nahmias
Published in: Science Translational Medicine, 2021, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abd6299

Microfluidic Concentric Gradient Generator Design for High-Throughput Cell-Based Studies

Author(s): Elishai Ezra Tsur, Michal Zimerman, Idan Maor, Avner Elrich, Yaakov Nahmias
Published in: Frontiers in Bioengineering and Biotechnology, Issue 5, 2017, ISSN 2296-4185
Publisher: Frontiers in Biotechnology and Bioengineering
DOI: 10.3389/fbioe.2017.00021

Microphysiological flux balance platform unravels the dynamics of drug induced steatosis

Author(s): Avner Ehrlich, Sabina Tsytkin-Kirschenzweig, Konstantinos Ioannidis, Muneef Ayyash, Anne Riu, Reine Note, Gladys Ouedraogo, Jan Vanfleteren, Merav Cohen, Yaakov Nahmias
Published in: Lab on a Chip, Issue 18/17, 2018, Page(s) 2510-2522, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8lc00357b

Nuclear receptors control pro-viral and antiviral metabolic responses to hepatitis C virus infection

Author(s): Gahl Levy, Naomi Habib, Maria Angela Guzzardi, Daniel Kitsberg, David Bomze, Elishai Ezra, Basak E Uygun, Korkut Uygun, Martin Trippler, Joerg F Schlaak, Oren Shibolet, Ella H Sklan, Merav Cohen, Joerg Timm, Nir Friedman, Yaakov Nahmias
Published in: Nature Chemical Biology, Issue 12/12, 2016, Page(s) 1037-1045, ISSN 1552-4450
Publisher: Nature Publishing Group
DOI: 10.1038/nchembio.2193

High-Reynolds Microfluidic Sorting of Large Yeast Populations

Author(s): Eliezer Keinan, Ayelet Chen Abraham, Aaron Cohen, Alexander I. Alexandrov, Reshef Mintz, Merav Cohen, Dana Reichmann, Daniel Kaganovich, Yaakov Nahmias
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-31726-6

Challenges and Opportunities in the Design of Liver-on-Chip Microdevices

Author(s): Avner Ehrlich, Daniel Duche, Gladys Ouedraogo, Yaakov Nahmias
Published in: Annual Review of Biomedical Engineering, Issue 21/1, 2019, Page(s) 219-239, ISSN 1523-9829
Publisher: Annual Reviews, Inc.
DOI: 10.1146/annurev-bioeng-060418-052305

Intellectual Property Rights

Patent (1)

METHOD TO REPRODUCE CIRCADIAN RHYTHMS ON A MICROFLUIDIC CHIP

Application/Publication number: 20 18051404
Date: 2018-12-27
Applicant(s): THE HEBREW UNIVERSITY OF JERUSALEM