Autocatalysis: A bottom-up approach to understanding the origins of life

Project Information

Autocat

Grant agreement ID: 681491

DOI 10.3030/681491

Project closed

EC signature date 27 March 2016

Start date 1 May 2016

End date 31 January 2022

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 278 073,00

EU contribution € 2 278 073,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

Oligomerization Driven by Phase Separation

Author(s): Iuliia Myrgorodska, Ignacio Colomer, Stephen P. Fletcher
Published in: ChemSystemsChem, Issue 2/5, 2020, ISSN 2570-4206
Publisher: Wiley-VCH
DOI: 10.1002/syst.201900059

A molecular assembler that produces polymers

Author(s): Anthonius H. J. Engwerda, Stephen P. Fletcher
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-17814-0

Coupled Metabolic Cycles Allow Out‐of‐Equilibrium Autopoietic Vesicle Replication

Author(s): Anthonius H. J. Engwerda, Josh Southworth, Maria A. Lebedeva, Robert J. H. Scanes, Philipp Kukura, Stephen P. Fletcher
Published in: Angewandte Chemie International Edition, Issue 59/46, 2020, Page(s) 20361-20366, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202007302

Dissipative self-assembly, competition and inhibition in a self-reproducing protocell model

Author(s): Elias A. J. Post, Stephen P. Fletcher
Published in: Chemical Science, Issue 11/35, 2020, Page(s) 9434-9442, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0sc02768e

A transient self-assembling self-replicator

Author(s): Ignacio Colomer, Sarah M. Morrow, Stephen P. Fletcher
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-018-04670-2

A chemically fuelled self-replicator

Author(s): Sarah M. Morrow, Ignacio Colomer, Stephen P. Fletcher
Published in: Nature Communications, Issue 10/1, 2019, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-08885-9

Controlling the Kinetics of Self-Reproducing Micelles by Catalyst Compartmentalization in a Biphasic System

Author(s): Elias A. J. Post, Stephen P. Fletcher
Published in: The Journal of Organic Chemistry, Issue 84/5, 2019, Page(s) 2741-2755, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.8b03149

Potential for minimal self-replicating systems in a dynamic combinatorial library of equilibrating imines

Author(s): Sarah M. Morrow, Andrew J. Bissette, Stephen P. Fletcher
Published in: Tetrahedron, Issue 73/33, 2017, Page(s) 5005-5010, ISSN 0040-4020
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.tet.2017.06.045

Self-reproducing micelles coupled to a secondary catalyst

Author(s): Elias A. J. Post, Andrew J. Bissette, Stephen P. Fletcher
Published in: Chemical Communications, Issue 54/63, 2018, Page(s) 8777-8780, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8cc02136h

Visualization of the spontaneous emergence of a complex, dynamic, and autocatalytic system

Author(s): Jaime Ortega-Arroyo, Andrew J. Bissette, Philipp Kukura, Stephen P. Fletcher
Published in: Proceedings of the National Academy of Sciences, Issue 113/40, 2016, Page(s) 11122-11126, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1602363113

Selection from a pool of self-assembling lipid replicators

Author(s): Ignacio Colomer, Arseni Borissov, Stephen P. Fletcher
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-13903-x

Emergence and Rearrangement of Dynamic Supramolecular Aggregates Visualized by Interferometric Scattering Microscopy

Author(s): Maria A. Lebedeva, Elena Palmieri, Philipp Kukura, Stephen P. Fletcher
Published in: ACS Nano, Issue 14/9, 2020, Page(s) 11160-11168, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.0c02414