Design and redesign of a plant immune receptor complex

Project Information

ImmunityByPairDesign

Grant agreement ID: 669926

DOI 10.3030/669926

Project closed

EC signature date 30 September 2015

Start date 1 October 2015

End date 30 September 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 499 978,00

EU contribution € 2 499 978,00

Coordinated by

THE SAINSBURY LABORATORY
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (19)

Mutual potentiation of plant immunity by cell-surface and intracellular receptors

Author(s): Bruno Pok Man Ngou, Hee-Kyung Ahn, Pingtao Ding, Jonathan D G Jones
Published in: Nature, Issue 592(7852), 2021, Page(s) 110-115, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-021-03315-7

Autoactive Arabidopsis RPS4 alleles require partner protein RRS1-R

Author(s): Hailong Guo, Shanshan Wang, Jonathan D G Jones
Published in: Plant Physiology, Issue 185/3, 2021, Page(s) 761-764, ISSN 0032-0889
Publisher: American Society of Plant Biologists
DOI: 10.1093/plphys/kiaa076

Plant NLRs get by with a little help from their friends

Author(s): Joanna M Feehan, Baptiste Castel, Adam R Bentham, Jonathan D G Jones
Published in: Current Opinion in Plant Biology, Issue 56, 2020, Page(s) 99-108, ISSN 1435-8603
Publisher: Georg Thieme Verlag
DOI: 10.1016/j.pbi.2020.04.006

Exploring folds, evolution and host interactions: understanding effector structure/function in disease and immunity

Author(s): Nitika Mukhi, Danylo Gorenkin, Mark J. Banfield
Published in: New Phytologist, Issue 2, 2020, Page(s) 326-333, ISSN 0028-646X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/nph.16563

Evolutionary trade-offs at the Arabidopsis WRR4A resistance locus underpin alternate Albugo candida race recognition specificities

Author(s): Baptiste Castel, Sebastian Fairhead, Oliver J Furzer, Amey Redkar, Shanshan Wang, Volkan Cevik, Eric B Holub, Jonathan D G Jones
Published in: The Plant Journal, Issue 107, 2021, Page(s) 1490-1502, ISSN 0960-7412
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/tpj.15396

Induced proximity of a TIR signaling domain on a plant-mammalian NLR chimera activates defense in plants

Author(s): Zane Duxbury, Shanshan Wang, Craig I MacKenzie, Jeannette L Tenthorey, Xiaoxiao Zhang, Sung Un Huh, Lanxi Hu, Lionel Hill, Pok Man Ngou, Pingtao Ding, Jian Chen, Yan Ma, Hailong Guo, Baptiste Castel, Panagiotis N Moschou, Maud Bernoux, Peter N Dodds, Russell E Vance, Jonathan D G Jones
Published in: Proceedings of the National Academy of Sciences of the United States of America, Issue 117(31), 2020, Page(s) 18832-18839, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2001185117

Perception of structurally distinct effectors by the integrated WRKY domain of a plant immune receptor

Author(s): Nitika Mukhi, Hannah Brown, Danylo Gorenkin, Pingtao Ding, Adam R Bentham, Clare E M Stevenson, Jonathan D G Jones, Mark J Banfield
Published in: Proceedings of the National Academy of Sciences of the United States of America, Issue 118(50), 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2113996118

Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

Author(s): Xinhua Sun, Dmitry Lapin, Joanna M Feehan, Sara C Stolze, Katharina Kramer, Joram A Dongus, Jakub Rzemieniewski, Servane Blanvillain-Baufumé, Anne Harzen, Jaqueline Bautor, Paul Derbyshire, Frank L H Menke, Iris Finkemeier, Hirofumi Nakagami, Jonathan D G Jones, Jane E Parker
Published in: Nature Communications, Issue Jun 7;12(1), 2021, Page(s) 3335, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-23614-x

A molecular roadmap to the plant immune system

Author(s): Adam R Bentham, Juan Carlos De la Concepcion, Nitika Mukhi, Rafał Zdrzałek, Markus Draeger, Danylo Gorenkin, Richard K Hughes, Mark J Banfield
Published in: Journal of Biological Chemistry, Issue 295(44), 2020, Page(s) 14916-14935, ISSN 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.rev120.010852

Two-faced TIRs trip the immune switch

Author(s): Jonathan D. G. Jones, Mark J. Banfield
Published in: Proceedings of the National Academy of Sciences, Issue 114/10, 2017, Page(s) 2445-2446, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1700954114

The highly buffered Arabidopsis immune signaling network conceals the functions of its components

Author(s): Rachel A. Hillmer, Kenichi Tsuda, Ghanasyam Rallapalli, Shuta Asai, William Truman, Matthew D. Papke, Hitoshi Sakakibara, Jonathan D. G. Jones, Chad L. Myers, Fumiaki Katagiri
Published in: PLOS Genetics, Issue 13/5, 2017, Page(s) e1006639, ISSN 1553-7404
Publisher: PLOS
DOI: 10.1371/journal.pgen.1006639

Pathogen perception by NLRs in plants and animals: Parallel worlds

Author(s): Zane Duxbury, Yan Ma, Oliver J. Furzer, Sung Un Huh, Volkan Cevik, Jonathan D.G. Jones, Panagiotis F. Sarris
Published in: BioEssays, Issue 38/8, 2016, Page(s) 769-781, ISSN 0265-9247
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/bies.201600046

Foundational and Translational Research Opportunities to Improve Plant Health

Author(s): Richard Michelmore, Gitta Coaker, Rebecca Bart, Gwyn Beattie, Andrew Bent, Toby Bruce, Duncan Cameron, Jeffery Dangl, Savithramma Dinesh-Kumar, Rob Edwards, Sebastian Eves-van den Akker, Walter Gassmann, Jean T. Greenberg, Linda Hanley-Bowdoin, Richard J. Harrison, Jagger Harvey, Ping He, Alisa Huffaker, Scot Hulbert, Roger Innes, Jonathan D. G. Jones, Isgouhi Kaloshian, Sophien Kamoun, Fumiaki Ka
Published in: Molecular Plant-Microbe Interactions, Issue 30/7, 2017, Page(s) 515-516, ISSN 0894-0282
Publisher: American Phytopathological Society
DOI: 10.1094/MPMI-01-17-0010-CR

Distinct modes of derepression of an Arabidopsis immune receptor complex by two different bacterial effectors

Author(s): Yan Ma, Hailong Guo, Lanxi Hu, Paula Pons Martinez, Panagiotis N. Moschou, Volkan Cevik, Pingtao Ding, Zane Duxbury, Panagiotis F. Sarris, and Jonathan D. G. Jones
Published in: PNAS, Issue 41, 2018, Page(s) 10218-10227, ISSN 1091-6490
Publisher: Proceedings of the National Academy of Sciences
DOI: 10.1073/pnas.1811858115

A pentangular plant inflammasome

Author(s): Jeffery L. Dangl, Jonathan D. G. Jones
Published in: Science, Issue 364/6435, 2019, Page(s) 31-32, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aax0174

Protein-protein interactions in the RPS4/RRS1 immune receptor complex

Author(s): Sung Un Huh, Volkan Cevik, Pingtao Ding, Zane Duxbury, Yan Ma, Laurence Tomlinson, Panagiotis F. Sarris, Jonathan D. G. Jones
Published in: PLOS Pathogens, Issue 13/5, 2017, Page(s) e1006376, ISSN 1553-7374
Publisher: PubMed.gov
DOI: 10.1371/journal.ppat.1006376

Phosphorylation-Regulated Activation of the Arabidopsis RRS1-R/RPS4 Immune Receptor Complex Reveals Two Distinct Effector Recognition Mechanisms

Author(s): Hailong Guo, Hee-Kyung Ahn, Jan Sklenar, Jianhua Huang, Yan Ma, Pingtao Ding, Frank L.H. Menke, Jonathan D.G. Jones
Published in: Cell Host & Microbe, Issue 27/5, 2020, Page(s) 769-781.e6, ISSN 1931-3128
Publisher: Cell Press
DOI: 10.1016/j.chom.2020.03.008

Diverse NLR immune receptors activate defence via the RPW 8‐ NLR NRG 1

Author(s): Baptiste Castel, Pok‐Man Ngou, Volkan Cevik, Amey Redkar, Dae‐Sung Kim, Ying Yang, Pingtao Ding, Jonathan D. G. Jones
Published in: New Phytologist, Issue 222/2, 2019, Page(s) 966-980, ISSN 0028-646X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/nph.15659

Estradiol-inducible AvrRps4 expression reveals distinct properties of TIR-NLR-mediated effector-triggered immunity

Author(s): Bruno Pok Man Ngou, Hee-Kyung Ahn, Pingtao Ding, Amey Redkar, Hannah Brown, Yan Ma, Mark Youles, Laurence Tomlinson, Jonathan D G Jones
Published in: Journal of Experimental Botany, Issue 71/6, 2020, Page(s) 2186-2197, ISSN 0022-0957
Publisher: Oxford University Press
DOI: 10.1093/jxb/erz571