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Reconstitution of Chromosome Replication and Epigenetic Inheritance

Publikacje

Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation

Autorzy: Allison W McClure; John FX Diffley
Opublikowane w: eLife, Numer 2, 2022, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.1101/2021.04.09.439171

The mechanism of eukaryotic CMG helicase activation

Autorzy: Max E. Douglas, Ferdos Abid Ali, Alessandro Costa, John F. X. Diffley
Opublikowane w: Nature, Numer 555/7695, 2018, Strona(/y) 265-268, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/nature25787

Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading

Autorzy: Gideon Coster, John F. X. Diffley
Opublikowane w: Science, Numer 357/6348, 2017, Strona(/y) 314-318, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.aan0063

Cryo-EM structure of a licensed DNA replication origin

Autorzy: Ferdos Abid Ali, Max E. Douglas, Julia Locke, Valerie E. Pye, Andrea Nans, John F. X. Diffley, Alessandro Costa
Opublikowane w: Nature Communications, Numer 8/1, 2017, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-017-02389-0

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication

Autorzy: Joseph T.P. Yeeles, Agnieska Janska, Anne Early, John F.X. Diffley
Opublikowane w: Molecular Cell, Numer 65/1, 2017, Strona(/y) 105-116, ISSN 1097-2765
Wydawca: Cell Press
DOI: 10.1016/j.molcel.2016.11.017

Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

Autorzy: Christoph F. Kurat, Joseph T.P. Yeeles, Harshil Patel, Anne Early, John F.X. Diffley
Opublikowane w: Molecular Cell, Numer 65/1, 2017, Strona(/y) 117-130, ISSN 1097-2765
Wydawca: Cell Press
DOI: 10.1016/j.molcel.2016.11.016

Cdt1 stabilizes an open MCM ring for helicase loading

Autorzy: Jordi Frigola, Jun He, Kerstin Kinkelin, Valerie E. Pye, Ludovic Renault, Max E. Douglas, Dirk Remus, Peter Cherepanov, Alessandro Costa, John F. X. Diffley
Opublikowane w: Nature Communications, Numer 8, 2017, Strona(/y) 15720, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/ncomms15720

CMG–Pol epsilon dynamics suggests a mechanism for the establishment of leading-strand synthesis in the eukaryotic replisome

Autorzy: Jin Chuan Zhou, Agnieszka Janska, Panchali Goswami, Ludovic Renault, Ferdos Abid Ali, Abhay Kotecha, John F. X. Diffley, Alessandro Costa
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 114/16, 2017, Strona(/y) 4141-4146, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.1700530114

Rpd3L Contributes to the DNA Damage Sensitivity of Saccharomyces cerevisiae Checkpoint Mutants

Autorzy: Belén Gómez-González, Harshil Patel, Anne Early, John F. X. Diffley
Opublikowane w: Genetics, Numer 211/2, 2019, Strona(/y) 503-513, ISSN 0016-6731
Wydawca: Genetics Society of America
DOI: 10.1534/genetics.118.301817

Mechanism of head-to-head MCM double-hexamer formation revealed by cryo-EM

Autorzy: Thomas C. R. Miller, Julia Locke, Julia F. Greiwe, John F. X. Diffley, Alessandro Costa
Opublikowane w: Nature, Numer 575/7784, 2019, Strona(/y) 704-710, ISSN 0028-0836
Wydawca: Nature Publishing Group
DOI: 10.1038/s41586-019-1768-0

Structure of DNA-CMG-Pol epsilon elucidates the roles of the non-catalytic polymerase modules in the eukaryotic replisome

Autorzy: Panchali Goswami, Ferdos Abid Ali, Max E. Douglas, Julia Locke, Andrew Purkiss, Agnieszka Janska, Patrik Eickhoff, Anne Early, Andrea Nans, Alan M. C. Cheung, John F. X. Diffley, Alessandro Costa
Opublikowane w: Nature Communications, Numer 9/1, 2018, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-018-07417-1

A DNA replication fork-centric view of the budding yeast DNA damage response

Autorzy: Allison W. McClure; Berta Canal; John F.X. Diffley
Opublikowane w: eLife, Numer 2, 2022, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.25418/crick.21164149

Budding yeast Rap1, but not telomeric DNA, is inhibitory for multiple stages of DNA replication in vitro.

Autorzy: Max E. Douglas; John F.X. Diffley
Opublikowane w: Nucleic Acids Research, Numer 1, 2021, ISSN 0305-1048
Wydawca: Oxford University Press
DOI: 10.1093/nar/gkab416

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