Modulation of RNA-based regulatory processes by viruses

Project Information

RegulRNA

Grant agreement ID: 647455

DOI 10.3030/647455

Project closed

EC signature date 7 April 2015

Start date 1 January 2016

End date 30 April 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 998 291,00

EU contribution € 1 998 291,00

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

Publications

Peer reviewed articles (10)

Prevention of dsRNA‐induced interferon signaling by AGO1x is linked to breast cancer cell proliferation

Author(s): Souvik Ghosh, Joao C Guimaraes, Manuela Lanzafame, Alexander Schmidt, Afzal Pasha Syed, Beatrice Dimitriades, Anastasiya Börsch, Shreemoyee Ghosh, Nitish Mittal, Thomas Montavon, Ana Luisa Correia, Johannes Danner, Gunter Meister, Luigi M Terracciano, Sébastien Pfeffer, Salvatore Piscuoglio, Mihaela Zavolan
Published in: The EMBO Journal, 2020, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2019103922

En avoir ou pas, l’interférence par l’ARNcomme défense antivirale chez les mammifères

Author(s): Olivier Petitjean, Thomas Montavon, Sébastien Pfeffer
Published in: Virologie, Issue 22(5), 2018, Page(s) 251-260, ISSN 1267-8694
Publisher: John Libbey Eurotext
DOI: 10.1684/vir.2018.0748

Roadblocks and fast tracks: How RNA binding proteins affect the viral RNA journey in the cell

Author(s): Erika Girardi, Sebastien Pfeffer, Thomas F. Baumert, Karim Majzoub
Published in: Seminars in Cell & Developmental Biology, 2020, ISSN 1084-9521
Publisher: Academic Press
DOI: 10.1016/j.semcdb.2020.08.006

Regulation of primary microRNA processing

Author(s): Antoine Creugny, Aurélie Fender, Sébastien Pfeffer
Published in: FEBS Letters, Issue 592/12, 2018, Page(s) 1980-1996, ISSN 0014-5793
Publisher: Elsevier BV
DOI: 10.1002/1873-3468.13067

On the Importance of Host MicroRNAs During Viral Infection

Author(s): Erika Girardi, Paula López, Sébastien Pfeffer
Published in: Frontiers in Genetics, Issue 9, 2018, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2018.00439

High-Throughput Fluorescence-Based Screen Identifies the Neuronal MicroRNA miR-124 as a Positive Regulator of Alphavirus Infection

Author(s): Paula López, Erika Girardi, Bryan C. Mounce, Amélie Weiss, Béatrice Chane-Woon-Ming, Mélanie Messmer, Pasi Kaukinen, Arnaud Kopp, Diane Bortolamiol-Becet, Ali Fendri, Marco Vignuzzi, Laurent Brino, Sébastien Pfeffer
Published in: Journal of Virology, Issue 94/9, 2020, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.02145-19

Importance des microARN cellulaires dans la régulation des infections virales

Author(s): Paula López, Erika Girardi, Sébastien Pfeffer
Published in: médecine/sciences, Issue 35/8-9, 2019, Page(s) 667-673, ISSN 0767-0974
Publisher: Editions E D K
DOI: 10.1051/medsci/2019130

Genome-Wide CRISPR-Cas9 Screen Reveals the Importance of the Heparan Sulfate Pathway and the Conserved Oligomeric Golgi Complex for Synthetic Double-Stranded RNA Uptake and Sindbis Virus Infection

Author(s): Olivier Petitjean, Erika Girardi, Richard Patryk Ngondo, Vladimir Lupashin, Sébastien Pfeffer
Published in: mSphere, Issue 5/6, 2020, ISSN 2379-5042
Publisher: American Society for Microbiology
DOI: 10.1128/msphere.00914-20

Human DICER helicase domain recruits PKR and modulates its antiviral activity

Author(s): Thomas C. Montavon, Morgane Baldaccini, Mathieu Lefèvre, Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Philippe Hammann, Johana Chicher, Sébastien Pfeffer
Published in: PLOS Pathogens, Issue 17/5, 2021, Page(s) e1009549, ISSN 1553-7374
Publisher: PLOS
DOI: 10.1371/journal.ppat.1009549

Cis regulation within a cluster of viral microRNAs

Author(s): Monika Vilimova, Maud Contrant, Ramy Randrianjafy, Philippe Dumas, Endrit Elbasani, Päivi M Ojala, Sébastien Pfeffer, Aurélie Fender
Published in: Nucleic Acids Research, 2021, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkab731

Other (4)

Cis regulation within a cluster of viral microRNAs

Author(s): Monika Vilimova, Maud Contrant, Ramy Randrianjafy, Philippe Dumas, Sébastien Pfeffer, Aurélie Fender
Published in: bioRxiv, 2021
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.11.19.389551

Determination of dsRNA interactome upon Sindbis virus infection in human cells identifies SFPQ as a critical proviral factor

Author(s): Erika Girardi, Mélanie Messmer, Paula Lopez, Aurélie Fender, Johana Chicher, Béatrice Chane-Woon-Ming, Philippe Hammann, Sébastien Pfeffer
Published in: bioRxiv, 2021
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.03.09.434591

Genome-wide CRISPR-Cas9 screen reveals common factors in dsRNA and Sindbis virus-induced cell death

Author(s): Olivier Petitjean, Erika Girardi, Richard Patryk Ngondo, Vladimir Lupashin, Sébastien Pfeffer
Published in: bioRxiv, 2020
Publisher: CSHL laboratory
DOI: 10.1101/2020.05.20.105528

Human Dicer helicase domain acts as an interaction platform to recruit PKR and dsRNA binding proteins during viral infection

Author(s): Thomas Montavon, Mathieu Lefèvre, Morgane Baldaccini, Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Philippe Hammann, Johana Chicher, Sébastien Pfeffer
Published in: bioRxiv, 2020
Publisher: CSHL laboratory
DOI: 10.1101/2020.05.14.095356