How to regenerate the mammalian kidney

Publications

Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection

Author(s): Vanessa Monteil, Matheus Dyczynski, Volker M Lauschke, Hyesoo Kwon, Gerald Wirnsberger, Sonia Youhanna, Haibo Zhang, Arthur S Slutsky, Carmen Hurtado del Pozo, Moritz Horn, Nuria Montserrat, Josef M Penninger, Ali Mirazimi
Published in: EMBO Molecular Medicine, 2020, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202013426

Kidney organoids for disease modeling

Author(s): Elena Garreta, Nuria Montserrat, Juan Carlos Izpisua Belmonte
Published in: Oncotarget, Issue 9/16, 2018, Page(s) 12552-12553, ISSN 1949-2553
Publisher: Impact Journals
DOI: 10.18632/oncotarget.24438

Studying Kidney Disease Using Tissue and Genome Engineering in Human Pluripotent Stem Cells

Author(s): Elena Garreta, Federico González, Núria Montserrat
Published in: Nephron, Issue 138/1, 2018, Page(s) 48-59, ISSN 1660-8151
Publisher: Karger
DOI: 10.1159/000480710

Roadblocks in the Path of iPSC to the Clinic

Author(s): Elena Garreta, Sonia Sanchez, Jeronimo Lajara, Nuria Montserrat, Juan Carlos Izpisua Belmonte
Published in: Current Transplantation Reports, Issue 5/1, 2018, Page(s) 14-18, ISSN 2196-3029
Publisher: Springer International Publishing
DOI: 10.1007/s40472-018-0177-x

Genome editing in human pluripotent stem cells: a systematic approach unrevealing pancreas development and disease

Author(s): Elena Garreta, Andres Marco, Juan Carlos Izpisua Belmonte, Nuria Montserrat
Published in: Stem Cell Investigation, Issue 3, 2016, Page(s) 76-76, ISSN 2313-0792
Publisher: AME Publishing Company
DOI: 10.21037/sci.2016.10.11

Regenerative strategies for kidney engineering

Author(s): Nuria Montserrat, Elena Garreta, Juan Carlos Izpisua Belmonte
Published in: The FEBS Journal, Issue 283/18, 2016, Page(s) 3303-3324, ISSN 1742-464X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/febs.13704

Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts

Author(s): Elena Garreta, Lorena de Oñate, M. Eugenia Fernández-Santos, Roger Oria, Carolina Tarantino, Andreu M. Climent, Andrés Marco, Mireia Samitier, Elena Martínez, Maria Valls-Margarit, Rafael Matesanz, Doris A. Taylor, Francisco Fernández-Avilés, Juan Carlos Izpisua Belmonte, Nuria Montserrat
Published in: Biomaterials, Issue 98, 2016, Page(s) 64-78, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2016.04.003

Tissue engineering by decellularization and 3D bioprinting

Author(s): Elena Garreta, Roger Oria, Carolina Tarantino, Mateu Pla-Roca, Patricia Prado, Francisco Fernández-Avilés, Josep Maria Campistol, Josep Samitier, Nuria Montserrat
Published in: Materials Today, 2017, ISSN 1369-7021
Publisher: Elsevier BV
DOI: 10.1016/j.mattod.2016.12.005

Characterization of the Epigenetic Changes During Human Gonadal Primordial Germ Cells Reprogramming

Author(s): C. Eguizabal, L. Herrera, L. De Oñate, N. Montserrat, P. Hajkova, J. C. Izpisua Belmonte
Published in: STEM CELLS, Issue 34/9, 2016, Page(s) 2418-2428, ISSN 1066-5099
Publisher: AlphaMed Press Inc
DOI: 10.1002/stem.2422

Active superelasticity in three-dimensional epithelia of controlled shape

Author(s): Ernest Latorre, Sohan Kale, Laura Casares, Manuel Gómez-González, Marina Uroz, Léo Valon, Roshna V. Nair, Elena Garreta, Nuria Montserrat, Aránzazu del Campo, Benoit Ladoux, Marino Arroyo, Xavier Trepat
Published in: Nature, Issue 563/7730, 2018, Page(s) 203-208, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-018-0671-4

Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells

Author(s): Elena Garreta, Patricia Prado, Carolina Tarantino, Roger Oria, Lucia Fanlo, Elisa Martí, Dobryna Zalvidea, Xavier Trepat, Pere Roca-Cusachs, Aleix Gavaldà-Navarro, Luca Cozzuto, Josep M. Campistol, Juan Carlos Izpisúa Belmonte, Carmen Hurtado del Pozo, Nuria Montserrat
Published in: Nature Materials, Issue 18/4, 2019, Page(s) 397-405, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-019-0287-6

Bioelectronic Recordings of Cardiomyocytes with Accumulation Mode Electrolyte Gated Organic Field Effect Transistors

Author(s): Adrica Kyndiah, Francesca Leonardi, Carolina Tarantino, Tobias Cramer, Ruben Millan-Solsona, Elena Garreta, Núria Montserrat, Marta Mas-Torrent, Gabriel Gomila
Published in: Biosensors and Bioelectronics, Issue 150, 2020, Page(s) 111844, ISSN 0956-5663
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.bios.2019.111844

Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2

Author(s): Vanessa Monteil, Hyesoo Kwon, Patricia Prado, Astrid Hagelkrüys, Reiner A. Wimmer, Martin Stahl, Alexandra Leopoldi, Elena Garreta, Carmen Hurtado del Pozo, Felipe Prosper, Juan Pablo Romero, Gerald Wirnsberger, Haibo Zhang, Arthur S. Slutsky, Ryan Conder, Nuria Montserrat, Ali Mirazimi, Josef M. Penninger
Published in: Cell, Issue 181/4, 2020, Page(s) 905-913.e7, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2020.04.004

The Nuclear Receptor ESRRA Protects from Kidney Disease by Coupling Metabolism and Differentiation

Author(s): Poonam Dhillon, Jihwan Park, Carmen Hurtado del Pozo, Lingzhi Li, Tomohito Doke, Shizheng Huang, Juanjuan Zhao, Hyun Mi Kang, Rojesh Shrestra, Michael S. Balzer, Shatakshee Chatterjee, Patricia Prado, Seung Yub Han, Hongbo Liu, Xin Sheng, Pieterjan Dierickx, Kirill Batmanov, Juan P. Romero, Felipe Prósper, Mingyao Li, Liming Pei, Junhyong Kim, Nuria Montserrat, Katalin Susztak
Published in: Cell Metabolism, 2020, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2020.11.011

Rethinking organoid technology through bioengineering

Author(s): Elena Garreta, Roger D. Kamm, Susana M. Chuva de Sousa Lopes, Madeline A. Lancaster, Ron Weiss, Xavier Trepat, Insoo Hyun, Nuria Montserrat
Published in: Nature Materials, 2020, ISSN 1476-1122
Publisher: Nature Publishing Group
DOI: 10.1038/s41563-020-00804-4

Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases

Author(s): Cian J. Lynch, Raquel Bernad, Ana Martínez-Val, Marta N. Shahbazi, Sandrina Nóbrega-Pereira, Isabel Calvo, Carmen Blanco-Aparicio, Carolina Tarantino, Elena Garreta, Laia Richart-Ginés, Noelia Alcazar, Osvaldo Graña-Castro, Gonzalo Gómez-Lopez, Irene Aksoy, Maribel Muñoz-Martín, Sonia Martinez, Sagrario Ortega, Susana Prieto, Elisabeth Simboeck, Alain Camasses, Camille Stephan-Otto Attolini
Published in: Nature Cell Biology, Issue 22/10, 2020, Page(s) 1223-1238, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-020-0573-1

Directed Differentiation of Human Pluripotent Stem Cells for the Generation of High-Order Kidney Organoids

Author(s): Idoia Lucía Selfa, Maria Gallo, Nuria Montserrat, Elena Garreta
Published in: Programmed Morphogenesis - Methods and Protocols, Issue 2258, 2021, Page(s) 171-192, ISBN 978-1-0716-1173-9
Publisher: Springer US
DOI: 10.1007/978-1-0716-1174-6_12

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