Unraveling changes in cellular gene expression during viral infection

Project Information

Profile Infection

Grant agreement ID: 638142

DOI 10.3030/638142

Project closed

EC signature date 29 May 2015

Start date 1 June 2015

End date 31 May 2020

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 500 000,00

EU contribution € 1 500 000,00

Coordinated by

WEIZMANN INSTITUTE OF SCIENCE
Israel

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Publications

Peer reviewed articles (6)

Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing

Author(s): Miri Shnayder, Aharon Nachshon, Benjamin Krishna, Emma Poole, Alina Boshkov, Amit Binyamin, Itay Maza, John Sinclair, Michal Schwartz, Noam Stern-Ginossar
Published in: mBio, Issue 9/2, 2018, Page(s) e00013-18, ISSN 2150-7511
Publisher: mBio
DOI: 10.1128/mBio.00013-18

A systematic view on influenza induced host shutoff

Author(s): Adi Bercovich-Kinori, Julie Tai, Idit Anna Gelbart, Alina Shitrit, Shani Ben-Moshe, Yaron Drori, Shalev Itzkovitz, Michal Mandelboim, Noam Stern-Ginossar
Published in: eLife, Issue 5, 2016, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.18311

Single cell analysis reveals human cytomegalovirus drives latently infected cells towards an anergic-like monocyte state

Author(s): Miri Shnayder, Aharon Nachshon, Batsheva Rozman, Biana Bernshtein, Michael Lavi, Noam Fein, Emma Poole, Selmir Avdic, Emily Blyth, David Gottlieb, Allison Abendroth, Barry Slobedman, John Sinclair, Noam Stern-Ginossar, Michal Schwartz
Published in: eLife, Issue 9, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.52168

Rho-Associated Coiled-Coil Kinase 1 Translocates to the Nucleus and Inhibits Human Cytomegalovirus Propagation

Author(s): Erez Eliyahu, Osnat Tirosh, Martina Dobesova, Aharon Nachshon, Michal Schwartz, Noam Stern-Ginossar
Published in: Journal of Virology, Issue 93/19, 2019, ISSN 0022-538X
Publisher: American Society for Microbiology
DOI: 10.1128/jvi.00453-19

m6A modification controls the innate immune response to infection by targeting type I interferons

Author(s): Roni Winkler, Ella Gillis, Lior Lasman, Modi Safra, Shay Geula, Clara Soyris, Aharon Nachshon, Julie Tai-Schmiedel, Nehemya Friedman, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Michal Mandelboim, Jacob H. Hanna, Schraga Schwartz, Noam Stern-Ginossar
Published in: Nature Immunology, Issue 20/2, 2019, Page(s) 173-182, ISSN 1529-2908
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-018-0275-z

Virus-Induced Changes in mRNA Secondary Structure Uncover cis-Regulatory Elements that Directly Control Gene Expression

Author(s): Orel Mizrahi, Aharon Nachshon, Alina Shitrit, Idit A. Gelbart, Martina Dobesova, Shirly Brenner, Chaim Kahana, Noam Stern-Ginossar
Published in: Molecular Cell, Issue 72/5, 2018, Page(s) 862-874.e5, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2018.09.003