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Novel Stromal Cell Therapy for Diabetic Kidney Disease

Resultado final

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Dissemination materials brochure flyer posters newsletters

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Website updated throughout the project

Publicaciones

Effects of mesenchymal stromal cells on regulatory T cells: Current understanding and clinical relevance

Autores: Neema Negi, Matthew D. Griffin
Publicado en: STEM CELLS, Edición 38/5, 2020, Página(s) 596-605, ISSN 1066-5099
Editor: AlphaMed Press Inc
DOI: 10.1002/stem.3151

Mesenchymal stromal cell–based therapies for acute kidney injury: progress in the last decade

Autores: Barbara Fazekas, Matthew D. Griffin
Publicado en: Kidney International, Edición 97/6, 2020, Página(s) 1130-1140, ISSN 0085-2538
Editor: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2019.12.019

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review

Autores: Sarah Elshahat, Paul Cockwell, Alexander P. Maxwell, Matthew Griffin, Timothy O’Brien, Ciaran O’Neill
Publicado en: PLOS ONE, Edición 15/3, 2020, Página(s) e0230512, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0230512

Burden of chronic kidney disease and rapid decline in renal function among adults attending a hospital-based diabetes center in Northern Europe

Autores: Tomás P Griffin, Paula M O'Shea, Andrew Smyth, Md Nahidul Islam, Deirdre Wall, John Ferguson, Esther O'Sullivan, Francis M Finucane, Sean F Dinneen, Fidelma P Dunne, David W Lappin, Donal N Reddan, Marcia Bell, Timothy O'Brien, Damian G Griffin, Matthew D Griffin
Publicado en: BMJ Open Diabetes Research & Care, Edición 9/1, 2021, Página(s) e002125, ISSN 2052-4897
Editor: BMJ Open Diabetes Research and Care
DOI: 10.1136/bmjdrc-2021-002125

Chronic kidney disease

Autores: Paola Romagnani, Giuseppe Remuzzi, Richard Glassock, Adeera Levin, Kitty J. Jager, Marcello Tonelli, Ziad Massy, Christoph Wanner, Hans-Joachim Anders
Publicado en: Nature Reviews Disease Primers, Edición 3, 2017, Página(s) 17088, ISSN 2056-676X
Editor: Nature Reviews
DOI: 10.1038/nrdp.2017.88

Anti-Donor Immune Responses Elicited by Allogeneic Mesenchymal Stem Cells and Their Extracellular Vesicles: Are We Still Learning?

Autores: Paul Lohan, Oliver Treacy, Matthew D. Griffin, Thomas Ritter, Aideen E. Ryan
Publicado en: Frontiers in Immunology, Edición 8, 2017, ISSN 1664-3224
Editor: Frontiers in Immunology
DOI: 10.3389/fimmu.2017.01626

Influence of Referral to a Combined Diabetology and Nephrology Clinic on Renal Functional Trends and Metabolic Parameters in Adults With Diabetic Kidney Disease

Autores: William P. Martin, Tomás P. Griffin, David W. Lappin, Damian G. Griffin, John P. Ferguson, Timothy O'Brien, Matthew D. Griffin
Publicado en: Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Edición 1/2, 2017, Página(s) 150-160, ISSN 2542-4548
Editor: Elsevier
DOI: 10.1016/j.mayocpiqo.2017.07.003

Interspecies Incompatibilities Limit the Immunomodulatory Effect of Human Mesenchymal Stromal Cells in the Rat

Autores: Paul Lohan, Oliver Treacy, Maurice Morcos, Ellen Donohoe, Yvonne O'donoghue, Aideen E. Ryan, Stephen J. Elliman, Thomas Ritter, Matthew D. Griffin
Publicado en: STEM CELLS, 2018, ISSN 1066-5099
Editor: AlphaMed Press Inc
DOI: 10.1002/stem.2840

Hyperactivation of nuclear receptor coactivators induces PERK-dependent cell death

Autores: Muhammad Mosaraf Hossain, David Barua, Vahid Arabkari, Nahidul Islam, Ananya Gupta, Sanjeev Gupta
Publicado en: Oncotarget, Edición 9/14, 2018, ISSN 1949-2553
Editor: Impact Journals
DOI: 10.18632/oncotarget.24451

Anti-donor antibody induction following intramuscular injections of allogeneic mesenchymal stromal cells

Autores: Senthilkumar Alagesan, Clara Sanz-Nogués, Xizhe Chen, Michael Creane, Thomas Ritter, Rhodri Ceredig, Timothy O'Brien, Matthew D Griffin
Publicado en: Immunology and Cell Biology, Edición 96/5, 2018, Página(s) 536-548, ISSN 0818-9641
Editor: Blackwell Publishing Inc.
DOI: 10.1111/imcb.12024

Phenotypic and functional heterogeneity of human intermediate monocytes based on HLA-DR expression

Autores: Eanna P Connaughton, Serika Naicker, Shirley A Hanley, Stephanie M Slevin, John K Eykelenboom, Noel F Lowndes, Timothy O'Brien, Rhodri Ceredig, Matthew D Griffin, Michael C Dennedy
Publicado en: Immunology and Cell Biology, 2018, ISSN 0818-9641
Editor: Blackwell Publishing Inc.
DOI: 10.1111/imcb.12032

The Promise of Mesenchymal Stem Cell Therapy for Diabetic Kidney Disease

Autores: Tomás P. Griffin, William Patrick Martin, Nahidul Islam, Timothy O’Brien, Matthew D. Griffin
Publicado en: Current Diabetes Reports, Edición 16/5, 2016, ISSN 1534-4827
Editor: Current Science Inc.
DOI: 10.1007/s11892-016-0734-6

Clinical Translation of Mesenchymal Stromal Cell Therapies in Nephrology

Autores: Norberto Perico, Federica Casiraghi, Giuseppe Remuzzi
Publicado en: Journal of the American Society of Nephrology, Edición 29/2, 2018, Página(s) 362-375, ISSN 1046-6673
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/ASN.2017070781

Mesenchymal Stromal Cells for AKI after Cardiac Surgery

Autores: Norberto Perico, Federica Casiraghi, Giuseppe Remuzzi
Publicado en: Journal of the American Society of Nephrology, 2018, Página(s) ASN.2017111207, ISSN 1046-6673
Editor: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/ASN.2017111207

The Immune System in Tissue Environments Regaining Homeostasis after Injury: Is “Inflammation” Always Inflammation?

Autores: Onkar P. Kulkarni, Julia Lichtnekert, Hans-Joachim Anders, Shrikant R. Mulay
Publicado en: Mediators of Inflammation, Edición 2016, 2016, Página(s) 1-9, ISSN 0962-9351
Editor: Hindawi Publishing Corporation
DOI: 10.1155/2016/2856213

Chronic kidney disease, health-related quality of life and their associated economic burden among a nationally representative sample of community dwelling adults in England

Autores: Nga T. Q. Nguyen, Paul Cockwell, Alexander P. Maxwell, Matthew Griffin, Timothy O’Brien, Ciaran O’Neill
Publicado en: PLOS ONE, Edición 13/11, 2018, Página(s) e0207960, ISSN 1932-6203
Editor: Public Library of Science
DOI: 10.1371/journal.pone.0207960

Defining reference intervals for a serum growth differentiation factor-15 (GDF-15) assay in a Caucasian population and its potential utility in diabetic kidney disease (DKD)

Autores: Siobhan M. Hamon, Tomás P. Griffin, Md Nahidul Islam, Deirdre Wall, Matthew D. Griffin, Paula M. O’Shea
Publicado en: Clinical Chemistry and Laboratory Medicine (CCLM), Edición 0/0, 2018, ISSN 1434-6621
Editor: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/cclm-2018-0534

Effect of Sodium Glucose Co-Transporter-2 Inhibition on the Aldosterone/Renin Ratio in Type 2 Diabetes Mellitus

Autores: Tomás Griffin, Md Islam, Liam Blake, Marcia Bell, Matthew Griffin, Paula O’Shea
Publicado en: Hormone and Metabolic Research, Edición 51/02, 2019, Página(s) 91-99, ISSN 0018-5043
Editor: Georg Thieme Verlag
DOI: 10.1055/a-0794-7026

Allogeneic Mesenchymal Stromal Cells (MSCs) are of Comparable Efficacy to Syngeneic MSCs for Therapeutic Revascularization in C57BKSdb/db Mice Despite the Induction of Alloantibody

Autores: A. Liew, C. Baustian, D. Thomas, E. Vaughan, C. Sanz-Nogués, M. Creane, X. Chen, S. Alagesan, P. Owens, J. Horan, P. Dockery, M. D. Griffin, A. Duffy, T. O’Brien
Publicado en: Cell Transplantation, 2018, Página(s) 096368971878486, ISSN 0963-6897
Editor: Cognizant Communication Corp.
DOI: 10.1177/0963689718784862

Mesenchymal Stromal Cells for Transplant Tolerance

Autores: Manuel Alfredo Podestà, Giuseppe Remuzzi, Federica Casiraghi
Publicado en: Frontiers in Immunology, Edición 10, 2019, ISSN 1664-3224
Editor: Frontiers in Immunology
DOI: 10.3389/fimmu.2019.01287

Progress toward the clinical application of mesenchymal stromal cells and other disease-modulating regenerative therapies

Autores: LaTonya J. Hickson, Sandra M. Herrmann, Bairbre A. McNicholas, Matthew D. Griffin
Publicado en: Kidney360, 2021, Página(s) 10.34067/KID.0005692020, ISSN 2641-7650
Editor: American Society of Nephrology
DOI: 10.34067/kid.0005692020

Human mesenchymal stromal cells broadly modulate high glucose-induced inflammatory responses of renal proximal tubular cell monolayers

Autores: Md Nahidul Islam, Tomás P. Griffin, Elizabeth Sander, Stephanie Rocks, Junaid Qazi, Joana Cabral, Jasmin McCaul, Tara McMorrow, Matthew D. Griffin
Publicado en: Stem Cell Research & Therapy, Edición 10/1, 2019, Página(s) online, ISSN 1757-6512
Editor: BioMed Central
DOI: 10.1186/s13287-019-1424-5

Plasma dephosphorylated-uncarboxylated Matrix Gla-Protein (dp-ucMGP): reference intervals in Caucasian adults and diabetic kidney disease biomarker potential

Autores: Tomás Patrick Griffin, Md Nahidul Islam, Deirdre Wall, John Ferguson, Damian Gerard Griffin, Matthew Dallas Griffin, Paula M. O’Shea
Publicado en: Scientific Reports, Edición 9/1, 2019, Página(s) online, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-54762-2

Editorial: Innovative Biologics and Drugs to Target Renal Inflammation

Autores: Matthew D. Griffin, Sundararaman Swaminathan
Publicado en: Frontiers in Pharmacology, Edición 11, 2020, Página(s) online, ISSN 1663-9812
Editor: Frontiers Media S.A.
DOI: 10.3389/fphar.2020.00038

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