Strengthening Animal Production and Health through the Immune Response

Project Information

SAPHIR

Grant agreement ID: 633184

DOI 10.3030/633184

Project closed

EC signature date 18 February 2015

Start date 1 March 2015

End date 28 February 2019

Funded under

• SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy

Total cost € 10 549 121,50

EU contribution € 8 999 996,25

Coordinated by

INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France

Deliverables

Documents, reports (20)

Responsiveness of porcine DC and B cells, and chicken DC, to individual and combined TLR ligands

Responsiveness of porcine DC and B cells and chicken DC to individual and combined TLR ligands report

Collected data for analysis of the factors involved in vaccine perception
SAPHIR project management guidelines
Identification of age categories of cattle that need to be targeted for vaccination in order to prevent virus circulation

Identification of age categories of cattle that need to be targeted for vaccination in order to prevent virus circulation (report).

Age-related innate responses to different TLR ligands in pig in vitro

Agerelated innate responses to different TLR ligands in pig in vitro report

Age-related innate responses to different adjuvants in cattle in vitro

Age-related innate responses to different adjuvants in cattle in vitro (report).

Outreach, training and dissemination plan

Outreach training and dissemination plan

Identification of immune correlates of protection that can be used to estimate the level of protection against infection by BRSV in the field

Identification of immune correlates of protection that can be used to estimate the level of protection against infection by BRSV in the field report

Effect of TLR-L on vaccine-induced immune responses and their protective value

Effect of TLR-L on vaccine-induced immune responses and their protective value (report)

Production and characterisation of the pre-fusion form of the BRSV F protein

Production and characterisation of the prefusion form of the BRSV F protein report

Protection against PRRSV by transfer of T and enriched CD8+ T cells

Report on protection against PRRSV by transfer of T and enriched CD8+ T cells

Conceptual framework of the factors involved in livestock producers’ attitude towards the intervention strategies against SAPHIR diseases, including vaccination

Conceptual framework of the factors involved in livestock producers attitude towards the intervention strategies against SAPHIR diseases including vaccination framework on farmers perception of interventions against SAPHIR diseases

Knowledge on the role of antibodies in protection

Report on knowledge on the role of antibodies in protection

Identification of CD8+ T cell PRRSV protein targets

Report on the identification of CD8 T cell PRRSV protein targets

Chicken DC and macrophage gene expression profiling in response to TLR ligands

Chicken DC and macrophage gene expression profiling in response to TLR ligands report

Optimized formulation for co-delivery of TLR-L and antigen in pigs and chickens

Optimized formulation for codelivery of TLRL and antigen in pigs and chickens report

Identification of the key factors that influence livestock producers’ behaviours towards vaccination and control of SAPHIR diseases, including information relevant to economic modelling for WP1

Identification of the key factors of farmers behaviours towards vaccination and control of SAPHIR diseases including information relevant to economic modelling for WP1

Economic analysis the SAPHIR diseases and their existing control measures

Framework for economic impact assessment of Saphir diseases and pathogens

Production losses caused by SAPHIR diseases and pathogens

Report on the estimation of production losses caused by SAPHIR diseases and pathogens

Farm-level impacts of SAPHIR diseases and pathogens

Report on Farmlevel impacts of SAPHIR diseases and pathogens

Other (5)

Workshop N°1 with stakeholders

Workshop N1 with stakeholders

Identification of the candidate risk factors of existing and new vaccines against the SAPHIR pathogens (wiki-website)
Launching of the Global Alliance for Veterinary Vaccinolog

Launching of the Global Alliance for Veterinary Vaccinology

Biorepository of biological samples and construction of a database data management

Biorepository of biological samples and construction of a database data management database

Workshop N°2 with stakeholders

Workshop N°2 with stakeholders.

Websites, patent fillings, videos etc. (2)

Project website on-line

Project website online

Integrated animal health management website on-line

Integrated animal health management website online

Publications

Peer reviewed articles (27)

Porcine B Cell Subset Responses to Toll-like Receptor Ligands

Author(s): Roman Othmar Braun, Sylvie Python, Artur Summerfield
Published in: Frontiers in Immunology, Issue 8, 2017, Page(s) 1-14, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2017.01044

Proteome analysis of bronchoalveolar lavage from calves infected with bovine respiratory syncytial virus—Insights in pathogenesis and perspectives for new treatments

Author(s): Sara Hägglund, Krister Blodörn, Katarina Näslund, Karin Vargmar, Sara Bergström Lind, Jia Mi, Mariluz Araínga, Sabine Riffault, Geraldine Taylor, John Pringle, Jean François Valarcher
Published in: PLOS ONE, Issue 12/10, 2017, Page(s) e0186594, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0186594

Linking disease epidemiology and livestock productivity: The case of bovine respiratory disease in France

Author(s): Alexis Delabouglise, Andrew James, Jean-François Valarcher, Sara Hagglünd, Didier Raboisson, Jonathan Rushton
Published in: PLOS ONE, Issue 12/12, 2017, Page(s) e0189090, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0189090

Recombinant anticoccidial vaccines - a cup half full?

Author(s): Damer P. Blake, Iván Pastor-Fernández, Matthew J. Nolan, Fiona M. Tomley
Published in: Infection, Genetics and Evolution, Issue 55, 2017, Page(s) 358-365, ISSN 1567-1348
Publisher: Elsevier BV
DOI: 10.1016/j.meegid.2017.10.009

Vaccines as alternatives to antibiotics for food producing animals. Part 1: challenges and needs

Author(s): Karin Hoelzer, Lisa Bielke, Damer P. Blake, Eric Cox, Simon M. Cutting, Bert Devriendt, Elisabeth Erlacher-Vindel, Evy Goossens, Kemal Karaca, Stephane Lemiere, Martin Metzner, Margot Raicek, Miquel Collell Suriñach, Nora M. Wong, Cyril Gay, Filip Van Immerseel
Published in: Veterinary Research, Issue 49/1, 2018, Page(s) 64, ISSN 1297-9716
Publisher: Springer Nature
DOI: 10.1186/s13567-018-0560-8

Label-Free Quantitative Proteomic Analysis of Differentially Expressed Membrane Proteins of Pulmonary Alveolar Macrophages Infected with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Its Attenuated Strain

Author(s): Zehui Qu, Fei Gao, Liwei Li, Yujiao Zhang, Yifeng Jiang, Lingxue Yu, Yanjun Zhou, Hao Zheng, Wu Tong, Guoxin Li, Guangzhi Tong
Published in: PROTEOMICS, Issue 17/23-24, 2017, Page(s) 1700101, ISSN 1615-9853
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/pmic.201700101

Neonatal porcine blood derived dendritic cell subsets show activation after TLR2 or TLR9 stimulation

Author(s): Sandra Vreman, Gael Auray, Huub F.J. Savelkoul, Annemarie Rebel, Artur Summerfield, Norbert Stockhofe-Zurwieden
Published in: Developmental & Comparative Immunology, Issue 84, 2018, Page(s) 361-370, ISSN 0145-305X
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.dci.2018.03.012

Recombinant porcine reproductive and respiratory syndrome virus expressing luciferase genes provide a new indication of viral propagation in both permissive and target cells

Author(s): Fei Gao, Zehui Qu, Liwei Li, Lingxue Yu, Yifeng Jiang, Yanjun Zhou, Shen Yang, Hao Zheng, Qinfeng Huang, Wu Tong, Guangzhi Tong
Published in: Research in Veterinary Science, Issue 107, 2016, Page(s) 132-140, ISSN 0034-5288
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.rvsc.2016.05.014

Genetic variability and limited clonality of Mycoplasma hyorhinis in pig herds

Author(s): Bettina Trüeb, Elena Catelli, Adrian Luehrs, Heiko Nathues, Peter Kuhnert
Published in: Veterinary Microbiology, Issue 191, 2016, Page(s) 9-14, ISSN 0378-1135
Publisher: Elsevier BV
DOI: 10.1016/j.vetmic.2016.05.015

Using a One Health approach to assess the impact of parasitic disease in livestock: how does it add value?

Author(s): JONATHAN RUSHTON, MIEGHAN BRUCE
Published in: Parasitology, 2016, Page(s) 1-11, ISSN 0031-1820
Publisher: Cambridge University Press
DOI: 10.1017/S0031182016000196

Development of cross-protective Eimeria-vectored vaccines based on apical membrane antigens

Author(s): Iván Pastor-Fernández, Sungwon Kim, Karen Billington, Janene Bumstead, Virginia Marugán-Hernández, Tatiana Küster, David J.P. Ferguson, Lonneke Vervelde, Damer P. Blake, Fiona M. Tomley
Published in: International Journal for Parasitology, Issue 48/7, 2018, Page(s) 505-518, ISSN 0020-7519
Publisher: Elsevier BV
DOI: 10.1016/j.ijpara.2018.01.003

Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic Cells

Author(s): Elise Bordet, Fany Blanc, Mathieu Tiret, Elisa Crisci, Edwige Bouguyon, Patricia Renson, Pauline Maisonnasse, Mickael Bourge, Jean-Jacques Leplat, Elisabetta Giuffra, Luc Jouneau, Isabelle Schwartz-Cornil, Olivier Bourry, Nicolas Bertho
Published in: Frontiers in Immunology, Issue 9, 2018, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2018.02299

Porcine Alveolar Macrophage-like cells are pro-inflammatory Pulmonary Intravascular Macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus

Author(s): Elise Bordet, Pauline Maisonnasse, Patricia Renson, Edwige Bouguyon, Elisa Crisci, Mathieu Tiret, Delphyne Descamps, Cindy Bernelin-Cottet, Céline Urien, François Lefèvre, Luc Jouneau, Olivier Bourry, Jean-Jacques Leplat, Isabelle Schwartz-Cornil, Nicolas Bertho
Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-018-28234-y

Synergistic effect of co-stimulation of membrane and endosomal TLRs on chicken innate immune responses

Author(s): Sungwon Kim, Pete Kaiser, Dominika Borowska, Lonneke Vervelde
Published in: Veterinary Immunology and Immunopathology, Issue 199, 2018, Page(s) 15-21, ISSN 0165-2427
Publisher: Elsevier BV
DOI: 10.1016/j.vetimm.2018.03.005

How to prevent viremia rebound? Evidence from a PRRSv data-supported model of immune response

Author(s): Natacha Go, Suzanne Touzeau, Zeenath Islam, Catherine Belloc, Andrea Doeschl-Wilson
Published in: BMC Systems Biology, Issue 13/1, 2019, ISSN 1752-0509
Publisher: BioMed Central
DOI: 10.1186/s12918-018-0666-7

Comparison of six commercial ELISAs for the detection of antibodies against porcine reproductive and respiratory syndrome virus (PRRSV) in field serum samples

Author(s): Kinga Biernacka, Katarzyna Podgórska, Anna Tyszka, Tomasz Stadejek
Published in: Research in Veterinary Science, Issue 121, 2018, Page(s) 40-45, ISSN 0034-5288
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.rvsc.2018.10.005

Galectin-3 inhibits replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp12 in vitro

Author(s): Liwei Li, Yanjun Zhou, Yifeng Jiang, Fei Gao, Tongling Shan, Kuan Zhao, Yujiao Zhang, Lin Li, Guangzhi Tong
Published in: Virus Research, Issue 253, 2018, Page(s) 87-91, ISSN 0168-1702
Publisher: Elsevier BV
DOI: 10.1016/j.virusres.2018.06.006

Porcine reproductive and respiratory syndrome virus expressing E2 of classical swine fever virus protects pigs from a lethal challenge of highly-pathogenic PRRSV and CSFV

Author(s): Fei Gao, Yifeng Jiang, Guoxin Li, Yanjun Zhou, Lingxue Yu, Liwei Li, Wu Tong, Hao Zheng, Yujiao Zhang, Hai Yu, Tongling Shan, Shen Yang, Huan Liu, Kuan Zhao, Guangzhi Tong
Published in: Vaccine, Issue 36/23, 2018, Page(s) 3269-3277, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1016/j.vaccine.2018.04.079

Development of Monoclonal Antibodies Specifically Recognizing the Nonstructural Protein 12 of Type 2 Porcine Reproductive and Respiratory Syndrome Virus

Author(s): Liwei Li, Fei Gao, Yifeng Jiang, Wu Tong, Hao Zheng, Tongling Shan, Ning Kong, Hai Yu, Deqiang Yang, Kuan Zhao, Yujiao Zhang, Guangzhi Tong
Published in: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, Issue 37/2, 2018, Page(s) 73-77, ISSN 2167-9436
Publisher: Mary Ann Liebert Inc.
DOI: 10.1089/mab.2017.0060

MOV10 inhibits replication of porcine reproductive and respiratory syndrome virus by retaining viral nucleocapsid protein in the cytoplasm of Marc-145 cells

Author(s): Kuan Zhao, Li-Wei Li, Yu-Jiao Zhang, Yi-Feng Jiang, Fei Gao, Guo-Xin Li, Ling-Xue Yu, Wen-Ying Zhao, Tong-Ling Shan, Yan-Jun Zhou, Guang-Zhi Tong
Published in: Biochemical and Biophysical Research Communications, Issue 504/1, 2018, Page(s) 157-163, ISSN 0006-291X
Publisher: Academic Press
DOI: 10.1016/j.bbrc.2018.08.148

Utilizing host endogenous microRNAs to negatively regulate the replication of porcine reproductive and respiratory syndrome virus in MARC-145 cells

Author(s): Liwei Li, Fei Gao, Hao Zheng, Yifeng Jiang, Wu Tong, Yanjun Zhou, Guangzhi Tong
Published in: PLOS ONE, Issue 13/7, 2018, Page(s) e0200029, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0200029

A DNA Prime Immuno-Potentiates a Modified Live Vaccine against the Porcine Reproductive and Respiratory Syndrome Virus but Does Not Improve Heterologous Protection

Author(s): Cindy Bernelin-Cottet, Céline Urien, Maxence Fretaud, Christelle Langevin, Ivan Trus, Luc Jouneau, Fany Blanc, Jean-Jacques Leplat, Céline Barc, Olivier Boulesteix, Mickaël Riou, Marilyn Dysart, Sophie Mahé, Elisabeth Studsrub, Hans Nauwynck, Nicolas Bertho, Olivier Bourry, Isabelle Schwartz-Cornil
Published in: Viruses, Issue 11/6, 2019, Page(s) 576, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11060576

Systems Immunology Characterization of Novel Vaccine Formulations for Mycoplasma hyopneumoniae Bacterins

Author(s): Anneleen M. F. Matthijs, Gaël Auray, Virginie Jakob, Obdulio García-Nicolás, Roman O. Braun, Irene Keller, Rémy Bruggman, Bert Devriendt, Filip Boyen, Carlos A. Guzman, Annelies Michiels, Freddy Haesebrouck, Nicolas Collin, Christophe Barnier-Quer, Dominiek Maes, Artur Summerfield
Published in: Frontiers in Immunology, Issue 10, 2019, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2019.01087

Electroporation of a nanoparticle-associated DNA vaccine induces higher inflammation and immunity compared to its delivery with microneedle patches in pigs

Author(s): Cindy Bernelin-Cottet, Céline Urien, Joanne McCaffrey, Damien Collins, Agnese Donadei, Dennis McDaid, Virginie Jakob, Christophe Barnier-Quer, Nicolas Collin, Edwige Bouguyon, Elise Bordet, Céline Barc, Olivier Boulesteix, Jean-Jacques Leplat, Fany Blanc, Vanessa Contreras, Nicolas Bertho, Anne C. Moore, Isabelle Schwartz-Cornil
Published in: Journal of Controlled Release, Issue 308, 2019, Page(s) 14-28, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.06.041

Predicting vaccine effectiveness in livestock populations: A theoretical framework applied to PRRS virus infections in pigs

Author(s): Vasiliki Bitsouni, Samantha Lycett, Tanja Opriessnig, Andrea Doeschl-Wilson
Published in: PLOS ONE, Issue 14/8, 2019, Page(s) e0220738, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0220738

Tn-sequencing of Mycoplasma hyopneumoniae and Mycoplasma hyorhinis mutant libraries reveals non-essential genes of porcine mycoplasmas differing in pathogenicity

Author(s): Bettina S. Trueeb, Simona Gerber, Dominiek Maes, Walid H. Gharib, Peter Kuhnert
Published in: Veterinary Research, Issue 50/1, 2019, Page(s) 55, ISSN 1297-9716
Publisher: Springer Nature
DOI: 10.1186/s13567-019-0674-7

A DNA-Modified Live Vaccine Prime–Boost Strategy Broadens the T-Cell Response and Enhances the Antibody Response against the Porcine Reproductive and Respiratory Syndrome Virus

Author(s): Cindy Bernelin-Cottet, Céline Urien, Elisabeth Stubsrud, Virginie Jakob, Edwige Bouguyon, Elise Bordet, Céline Barc, Olivier Boulesteix, Vanessa Contreras, Christophe Barnier-Quer, Nicolas Collin, Ivan Trus, Hans Nauwynck, Nicolas Bertho, Isabelle Schwartz-Cornil
Published in: Viruses, Issue 11/6, 2019, Page(s) 551, ISSN 1999-4915
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v11060551

Conference proceedings (27)

"“Exploring the thinking of ‘Good Farming’ in pig production industries between Europe and China: a sociological analysis of farmers’ attitudes towards animal diseases and vaccination practices"""

Author(s): Chan, R. and Enticott, G.
Published in: n/a, Issue 2017, 2017
Publisher: -

Dissolving microneedle patches adjuvanted with different Toll like receptor agonists in pigs: local immune response by macroscopic and histologic evaluation

Author(s): S. Vremen, J. McCaffrey, N. Stochofe, A.C, Moore
Published in: Skin Vaccination Summit, Issue may 2017, 2017, Page(s) 36
Publisher: -

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Author(s): Sabine Riffault
Published in: Issue 12 December 2017, 2017
Publisher: 7e Workshop CoReVac / I-REIVAC, Vaccination in the extreme ages of life

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Author(s): Sabine Riffault
Published in: -, Issue 26 - 27 October 2017, 2017
Publisher: Colloque Département Sciences de la Vie de l’Université Paris-Saclay

A one health perspective for vaccine strategies against bronchiolitis

Author(s): Gabriela Pretre, Stéphane Claverol, Marie-Claude Hygonenq, Christine Citti1 and Eric Baranowski
Published in: Abstract Book of the UK Veterinary Vaccinology Network Conference 2017, Issue 16-17 January 2017, 2017
Publisher: UK Veterinary Vaccinology Network

Le protéome membranaire de Mycoplasma bovis: à la recherche d’antigènes stables chez un pathogène hypervariable

Author(s): Gabriela Pretre, Marie-Claude Hygonenq, Stéphane Claverol, Christine Citti and Eric Baranowski
Published in: Abstract Book of the 7e Colloque International Francophone de Microbiologie Animale, Issue 26-27 March 2017, 2017, Page(s) 37
Publisher: Université de Liège

Deciphering host responses to Eimeria infections for implementing integrated breeding strategies for improved resistance to coccidiosis

Author(s): Marie-Hélène Pinard-van der Laan
Published in: Abstract Book of the 12th International Coccidiosis Conference (ICC-12), Issue June 26-30, 2017, 2017, Page(s) 41-42
Publisher: American Society of Parasitologists (ASP)

Genetic individual variability of vaccine responses in pigs

Author(s): Fany Blanc, Gaëtan Lemonnier, Jean-Jacques Leplat, Edwige Bouguyon, Yvon Billon, Jordi Estellé and Claire Rogel-Gaillard
Published in: Abstract Book of the 36th International Society for Animal Genetics (ISAG) Conference, Issue July 16-21, 2017, 2017, Page(s) 22
Publisher: Society of Animal Genetics

How to prevent viremia rebound? Evidence from a PRRSv data-supported model of the immune response

Author(s): N.Go, S. Touzeau, C.Belloc, A. Doeschl-Wilson
Published in: ModAH Modelling in Animal Health, Issue 07.6.2017, 2017
Publisher: -

New PRRS disease phenotypes as vaccine & genetic improvement targets

Author(s): A.Doeschl-Wilson
Published in: international PRRS symposium 2017, Issue 2.12.2017, 2017
Publisher: -

Control measures for bovine respiratory syncytial infection

Author(s): Hägglund S and Valarcher JF
Published in: European Buiatrics Forum, 2015, ISBN 2-9036-23457
Publisher: Société Francais de Buiatrie

Development of a DNA-loaded dissolving microneedle platform for veterinary vaccination

Author(s): J. McCaffrey, C. Bernelin, C.Urien, V. Jakob, C. Barnier, N. Bertho, I. Schwartz, D. McDaid, A.Moore
Published in: Focused Meeting 2016 – Irish Division: Exploring the Microbe–Immune System Interface, Issue september 2016, 2016, Page(s) 54
Publisher: Irish Division: Exploring the Microbe–Immune System Interface

Development of a dissolving microneedle patch for delivery of a veterinary DNA vaccine

Author(s): J. McCaffrey, C. Bernelin, N. Bertho, I. Schwartz, V. Jakob, C. Barnier, D.McDaid, A.Moore
Published in: The 4th International Conference on Microneedles, Issue may 2016, 2016, Page(s) 18
Publisher: The 4th International Conference on Microneedles

Vaccination with different Toll-like receptor agonist by dissolving microneedle patches to pigs

Author(s): Vreman S., McCaffrey J., Rebel A., Moore A., Stockhofe-Zurwieden N.
Published in: 2017, Page(s) Poster
Publisher: Skin vaccination summit

Differential responsiveness of neonatal and adult porcine dendritic cells and monocytes after TLR2 and TLR9 stimulation of PBMCs

Author(s): Vreman S., Auray G., Savelkoul HFJ, Rebel A., Summerfield A., Stockhofe-Zurwieden N.
Published in: 2017, Page(s) Poster
Publisher: -

Dendritic cells and Porcine Reproductive and Respiratory Syndrome Virus interactions in the lung and their impact on the T helper immune response.

Author(s): BORDET E, BLANC F, TIRET M, CRISCI E, BOUGUYON E, RENSON P, MAISONNASSE P, BOURGE M, LEPLAT JJ, GIUFFRA E, JOUNEAU L, SCHWARTZ-CORNIL I, BOURRY O, BERTHO N.
Published in: "Abstract book of the ""Immunology of Domestic Animals""", 2018
Publisher: -

Porcine Alveolar Macrophage-like cells are pro-inflammatory Pulmonary Intravascular Macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus.

Author(s): BORDET E, MAISONNASSE P, RENSON P, BOUGUYON E, CRISCI E, TIRET M, DESCAMPS D, BERNELIN-COTTET C, URIEN C, LEFÈVRE F, JOUNEAU L, BOURRY O, LEPLAT JJ, SCHWARTZ-CORNIL I, BERTHO N.
Published in: "Abstract book of the ""Immunology of Domestic Animals""", 2018
Publisher: -

Immunogenicity of DNA vaccines delivered by patches and electroporation in pig skin

Author(s): Bernelin-Cottet C., Urien C., Blanc F., Leplat J.J., McCaffrey J., Collins D., Jakob V., Bordet E., Barc C., Contreras V., Bertho N., McDaid D., Collin N., Barnier-Quer C., Moore A., Schwartz-Cornil I.
Published in: Abstract book of European Workshop in Veterinary Immunology, 2018
Publisher: -

A prime with naked DNA improves the immune responses induced by a modified live vaccine against Porcine Reproductive and Respiratory Syndrome Virus

Author(s): Bernelin-Cottet C., Urien C., Blanc F., Jakob V., Bordet E., Barc C., Contreras V., Bertho N., Barnier C., Collin N., Studsrub E., Brunsvik Fredriksen A., Trus I., Nauwynck H., and Schwartz-Cornil I.
Published in: Abstract book of European congress in Immunonology, 2018
Publisher: -

Immunogenicity of DNA vaccines delivered by patches and electroporation in pig skin

Author(s): Bernelin-Cottet C., Urien C., Blanc F., Leplat J.J., McCaffrey J., Collins D., Jakob V., Bordet E., Barc C., Contreras V., Bertho N., McDaid D., Collin N., Barnier-Quer C., Moore A., Schwartz-Cornil I.
Published in: Abstract book of European congress in Immunonology, 2018
Publisher: -

Multidisciplinary approaches to livestock production in SAPHIR

Author(s): Marie-Hélène Pinard
Published in: Abstract book of 69th Annual Meeting of the European Federation of Animal Science (EAAP), 2018
Publisher: -

What potential of genome-wide integrative approaches to predict vaccine responses?

Author(s): Blanc F, Maroilley T, Pinard-van der Laan MH, Lemonnier G, Leplat JJ, Bouguyon E, Billon Y, Bidanel JP, Bed’Hom B, Estellé J, Kim S, Vervelde L, Blake D, and Rogel-Gaillard C
Published in: Abstract book of 69th Annual Meeting of the European Federation of Animal Science (EAAP), 2018
Publisher: -

Multi-disciplinary approaches for improving sustainable livestock production: research needs, opportunities and difficulties.

Author(s): Marie-Hélène Pinard
Published in: Abstract book of 69th Annual Meeting of the European Federation of Animal Science (EAAP), 2018
Publisher: -

Individual genetic variability of vaccine responses in pigs.

Author(s): Blanc F, Maroilley T, Lemonnier G, Leplat JJ, Bouguyon E, Billon, Bouchez O, Bidanel JP, Bed’Hom 1, Estellé J and Rogel-Gaillard C
Published in: "Abstract book of the ""Immunology of Domestic Animals""", 2018
Publisher: -

Genetic variability of vaccine responses in pigs: application to vaccines against Mycoplasma hyopneumonia and Influenza A virus

Author(s): Blanc F, Maroilley T, Lemonnier G, Leplat JJ, Bouguyon E, Billon, Bouchez O, Bidanel JP, Bed’Hom B, Estellé J and Rogel-Gaillard C
Published in: Abstract book of 6th European Veterinary Immunology Workshop (EVIW), 2018
Publisher: -

The membrane core proteome of Mycoplasma bovis: A conserved set of antigens within a rapidly changing pathogen

Author(s): Pretre G, Maillard R, Foucras G, Assié S, Hygonenq MC, Claverol S, Giammarinaro P, Nouvel LX, Guo A, Citti C, Baranowski E.
Published in: 22th Congress of the International Organization for Mycoplasmology (IOM2018), 2018
Publisher: -

Inactivated porcine reproductive and respiratory syndrome virus adjuvanted with single Toll Like receptor 2, 7 and 9 ligands induces low antibody responses and limited protection

Author(s): Sandra Vreman, Joanne McCaffrey, Ivan Trus, Annemarie Rebel, Hans Nauwynck, Anne Moore, Norbert Stockhofe-Zurwieden
Published in: 2018
Publisher: -

Thesis and dissertations (1)

Développement d’un vaccin à ADN contre le Syndrome Dysgénésique et Respiratoire Porcin (PRRSV)

Author(s): Cindy Bernelin
Published in: 2019
Publisher: -