Objective
Water-borne viral diseases pose high risks for public health worldwide. The urban wastewater contains large number of pathogen viruses, and even the most advanced wastewater treatment is not safe for full removal of virus particles.
The conventional biological water quality indicators do not provide adequate information about the presence of pathogenic viruses. The currently available reliable virus test - based on molecular biology - is expensive, time consuming and labour intensive, thus limited to few laboratories with sophisticated facilities and well-trained personnel, even though the protection of water networks against pathogenic viruses is crucial.
In this project we aim to develop a novel, cost effective, portable, on-site detection system, which is capable for monitoring human enteric viruses in different freshwater bodies.
The method is based on disposable microfluidic chip, in which the virus particles can be up-concentrated and detected by electrical readout with a detection limit of 0.01-1 virus/L. We will focus on selective detection of norovirus, Hepatitis A and rotavirus (the most prevalent viruses), but the sensor is capable to detect any other virus with relevant functionalization.
The “plug-and-play” virus sensor chip will be integrated into a measurement unit, which will send the data to the monitoring station.
The project will include laboratory and field tests and validation of the monitoring unit, development an early warning system and epidemic risk assessment, provide with exploitation possibilities at the end-users, economical assessment for positive production capacity and preparation for future standardization.
Fields of science
- engineering and technologyenvironmental engineeringwater treatment processeswastewater treatment processes
- natural sciencesbiological sciencesmicrobiologyvirology
- natural sciencesearth and related environmental scienceshydrology
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensors
- natural sciencesbiological sciencesmolecular biology
Programme(s)
Call for proposal
FP7-NMP-2013-SMALL-7
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Funding Scheme
CP-FP - Small or medium-scale focused research projectCoordinator
2800 Kongens Lyngby
Denmark
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Participants (13)
3450 ALLEROD
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2970 HERSHOLM
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00133 Roma
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1111 Budapest
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5032 GEMBLOUX
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64625 BENSHEIM
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2970 HOERSHOLM
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10787 Berlin
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411 13 Goteborg
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00189 Rome
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1300 254 LISBOA
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1250-144 LISBOA
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050096 Bucuresti
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