Skip to main content
European Commission logo
English English
CORDIS - EU research results
CORDIS
CORDIS Web 30th anniversary CORDIS Web 30th anniversary
Content archived on 2024-06-18

Antibody-functionalised cardiovascular stents for improved biocompatibility and reduced restenosis

Objective

An industry-academia collaboration is proposed wherein two industry and three academic partners will establish a lasting, inter-national partnership for transfer of knowledge in biomaterials engineering. The partners have synergistic competences in the medical device sector, and, aided by a schedule of staff secondments and networking events, their relevant niche expertise will be shared and transferred intersectorally. In all 16 researchers will be supported.
Coronary artery disease accounts for two million deaths per year in Europe. The long-term outcome for patients is poor: 15% die or experience re-infarction within 30 days of initial diagnosis, while over 30% are re-hospitalised within 1 year. The estimated cost to the EU economy is €192 billion/year. The over-riding S&T objective of this collaboration is to develop a biomimetic cardiovascular stent prototype, by surface functionalisation with human antibody fragments, for improved coating by epithelial precursor cells in vivo. Sophisticated protein engineering and (nano)materials analysis from academic partners will interface with focused manufacturing and market experience of industry partners to deliver a stent with improved biocompatibility, reduced re-narrowing of arteries and superior clinical performance. Partners in interventional cardiology and industrial stent manufacturing will ensure clinical relevance and market-driven focus throughout design, development and post-project market entry.
The collaboration will develop skill sets of individual researchers, strengthen research capacity at partner institutions and support important extant biomedical device clusters in Ireland and Poland. The clinical end product will significantly improve patient outcomes and quality of life for Europe’s citizens; reduce costs for health care providers; and strengthen the European biomedical industry, leading to creation / retention of wealth in Europe and job creation in the European medical devices sector.

Call for proposal

FP7-PEOPLE-2012-IAPP
See other projects for this call

Coordinator

UNIVERSITY OF GALWAY
EU contribution
€ 405 039,85
Address
UNIVERSITY ROAD
H91 Galway
Ireland

See on map

Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mari Vahey (Ms.)
Links
Total cost
No data

Participants (5)