Objective
Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 individuals to investigate:
• The fuel mediated in utero hypothesis
• The accelerated postnatal weight gain hypothesis
• The mismatch hypothesis.
Scientific and technical expertise in placental biology, epigenetics and metabolomics will provide understanding at the cellular and molecular level, and refined strategies for intervention in pregnancy and early post natal life to prevent obesity.
Using existing cohort studies, ongoing and novel intervention studies and a basic science programme, we will provide the scientific foundations for evidence based recommendations for optimal EarlyNutrition that incorporate long-term health outcomes, focusing on 4 Target Groups: women before pregnancy; pregnant women; infants (incl. breastfeeding); young children.
Evidence is produced from animal and placental studies (Theme 1; T1), prospective cohort studies (T2), and randomised controlled trials in pregnant women and infants (T3). T4 covers scientific strategic integration, recommendation development and dissemination, including systematic reviews and behaviour change approaches.
A strong multi-disciplinary team of international leaders in the field including collaborators from USA and Australia achieves balance and complementarity.
The project’s impact comprises definitive evidence on early nutrition effects on health, enhanced EU and global policies, major economic benefits through obesity prevention and value-added nutritional products, and practical recommendations on optimal nutrition in Target Groups. Wide dissemination will be achieved through active engagement with stakeholders.
Fields of science
Call for proposal
FP7-KBBE-2011-5
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Funding Scheme
CP-IP - Large-scale integrating projectCoordinator
80539 MUNCHEN
Germany
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Participants (39)
WC2R 2LS London
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8010 Graz
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2300 Kobenhavn S
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30003 Murcia
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NG7 2RD Nottingham
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0456 Oslo
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4 Dublin
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1081 HV Amsterdam
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43003 Tarragona
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2333 ZA Leiden
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SO17 1BJ Southampton
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3015 GD Rotterdam
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18071 Granada
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1165 Kobenhavn
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02 091 Warszawa
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CB2 1TN Cambridge
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T12 YN60 Cork
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20122 Milano
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04730 Warszawa
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10561 Athina
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1050 Bruxelles / Brussel
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SE1 7EH LONDON
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2333 BZ LEIDEN
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1030 Wien
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6718 ZB Ede Gld
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3584 CT Utrecht
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68165 MANNHEIM
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28050 Madride
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94607 OAKLAND CA
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0248110 WELLESLEY MA
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78701 2982 Austin
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44106 7037 Cleveland Ohio
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6008 SUBIACO
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3052 Parkville
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5005 Adelaide
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4000 LIEGE
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Participation ended
1081 HV Amsterdam
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1081 HV Amsterdam
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2333 BZ Leiden
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