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Recruitment and activation of brown adipocytes as preventive and curative therapy for type 2 diabetes

Cel

The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the DIABAT network (van Marken LIchtenbelt et al., N. Engl. J. Med. 360, 1500, 2009; Virtanen…, Enerbäck & Nuutila, N. Engl. J. Med. 360, 1518, 2009) along with sharp rise in insight in cellular, genetic, and regulatory mechanisms from animal studies. Therefore, the DIABAT project aims at recruiting and re-activating endogenous energy-dissipating BAT as a preventive and/or remedial measure for weight and blood sugar control in obesity-related type 2 diabetes (“diabesity”), thereby halting or preventing destruction and facilitating recovery of pancreatic beta-cells under diabetic conditions.

Dziedzina nauki

Program(-y)

Temat(-y)

Zaproszenie do składania wniosków

FP7-HEALTH-2011-two-stage
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System finansowania

CP-FP - Small or medium-scale focused research project

Koordynator

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Wkład UE
€ 566 182,00
Adres
IM NEUENHEIMER FELD 280
69120 Heidelberg
Niemcy

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Region
Baden-Württemberg Karlsruhe Heidelberg, Stadtkreis
Rodzaj działalności
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Koszt całkowity
Brak danych

Uczestnicy (20)

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Ostatnia aktualizacja: 27 Sierpnia 2017

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Permalink: https://cordis.europa.eu/project/id/278373/pl

European Union, 2024