Descrizione del progetto
Virtual Physiological Human
Medicine is undergoing a revolution that is transforming the nature of healthcare from reactive to preventive. The changes are catalyzed by a new systems approach to disease which focuses on integrated diagnosis, treatment and prevention of disease in individuals. This will replace our current mode of medicine over the coming years with a personalized predictive treatment . While the goal is clear, the path is fraught with challenges.P-medicine brings together international leaders in their fields to create an infrastructure that will facilitate this translation from current practice to personalized medicine. In achieving this objective p-medicine has formulated a coherent, integrated workplan for the design, development, integration and validation of technologically challenging areas of today.Our emphasis is on formulating an open, modular framework of tools and services, so that p-medicine can be adopted gradually, including efficient secure sharing and handling of large personalized data sets, enabling demanding Virtual Physiological Human (VPH) multiscale simulations (in silico oncology), building standards-compliant tools and models for VPH research, drawing on the VPH Toolkit and providing tools for large-scale, privacy-preserving data and literature mining, a key component of VPH research. We will ensure that privacy, non-discrimination, and access policies are aligned to maximize protection of and benefit to patients. The p-medicine tools and technologies will be validated within the concrete setting of advanced clinical research. Pilot cancer trials have been selected based on clear research objectives, emphasising the need to integrate multilevel datasets, in the domains of Wilms tumour, breast cancer and leukaemia. To sustain a self-supporting infrastructure realistic use cases will be built that will demonstrate tangible results for clinicians.The project is clinically driven and promotes the principle of open source and open standards.
Campo scientifico
Not validated
Not validated
- social sciencespolitical sciencespolitical transitionsrevolutions
- medical and health sciencesclinical medicineoncologybreast cancer
- medical and health scienceshealth sciencespersonalized medicine
- natural sciencescomputer and information sciencescomputational sciencemultiphysics
- medical and health sciencesclinical medicineoncologyleukemia
Argomento(i)
Invito a presentare proposte
FP7-ICT-2009-6
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Meccanismo di finanziamento
CP - Collaborative project (generic)Coordinatore
66123 Saarbrucken
Germania
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Partecipanti (21)
9830 Sint-Martens-Latem
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6300 Zug
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1206 Geneve
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Partecipazione conclusa
24118 Kiel
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80686 Munchen
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30625 Hannover
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66386 St Ingbert
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30167 Hannover
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40225 Dusseldorf
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28040 Madrid
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106 82 ATHINA
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167 77 Athina
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70013 Irakleio
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49527 Petach Tikva
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20121 Milano
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060 0808 Sapporo
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5656 AG Eindhoven
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61-704 POZNAN
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WC1E 6BT LONDON
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OX1 2JD Oxford
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23562 Lübeck
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