Magnetic Scaffolds for in vivo Tissue Engineering

Informations projet

MAGISTER

N° de convention de subvention: 214685

Projet clôturé

Date de début 1 Decembre 2008

Date de fin 30 Novembre 2012

Financé au titre de

• Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies

Coût total € 11 085 124,00

Contribution de l’UE € 8 278 091,00

Coordonné par

CONSIGLIO NAZIONALE DELLE RICERCHE
Italy

Objectif

The main driving idea of the project is the creation of conceptually new type of scaffolds able to be manipulated in situ by means of magnetic forces. This approach is expected to generate scaffolds with such characteristics as multiple use and possibly multipurpose delivery in order to repair large bone defects and ostheocondral lesions in the articular surface of the skeletal system. The major limitations of the scaffolds for bone and cartilage regeneration nowadays available in the market are related to the difficulties in controlling cell differentiation and angiogenesis processes and to obtain stable scaffold implantation in the pathological site. . . Several attempts have been performed over the last years in order to provide scaffolds for tissue engineering, but nowadays there is no way to grant that tissue regeneration take place in the pathological site. The provision in vivo of the scaffold with staminal cells or /and growth factors in order to drive the tissue differentiation process and parallel angiogenesis represents nowadays one of most challenging requests [Ref. Nanomedicine roadmap]. The Consortium aims to elaborate, investigate and fabricate new kind of scaffolds – magnetic scaffolds (MagS) - characterized by strongly enhanced control and efficiency of the tissue regeneration and angiogenic processes. The magnetic moment of the scaffolds enables them with a fascinating possibility of being continuously controlled and reloaded from external supervising center with all needed scaffold materials and various active factors (AF). Such a magnetic scaffold can be imagined as a fixed “station” that offers a long-living assistance to the tissue engineering, providing thus a unique possibility to adjust the scaffold activity to the personal needs of the patient.

Champ scientifique

• medical and health sciences › medical biotechnology › tissue engineering
• medical and health sciences › medical biotechnology › nanomedicine

Mots‑clés

• Magnetic Scaffolds
• Tissue Engineering
• angiogenesis

Programme(s)

• FP7-NMP - Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies

Thème(s)

• NMP-2007-2.3-1 - Highly porous bioactive scaffolds favouring angiogenesis for tissue engineering

Appel à propositions

FP7-NMP-2007-LARGE-1
Voir d’autres projets de cet appel

Régime de financement

CP-IP - Large-scale integrating project

Coordinateur

CONSIGLIO NAZIONALE DELLE RICERCHE

• Contribution de l’UE: € 1 575 606,00
• Adresse: PIAZZALE ALDO MORO 7 ; 00185 Roma ; Italie
• Région: Centro (IT) › Lazio › Roma
• Type d’activité: Research Organisations
• Contact administratif: Valentin Dediu (Dr.)
• Coût total: Aucune donnée

Participants (19)

ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA

Italie

• Contribution de l’UE: € 1 075 600,00
• Adresse: VIA ZAMBONI 33 ; 40126 Bologna
• Région: Nord-Est › Emilia-Romagna › Bologna
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Maurilio Marcacci (Prof.)
• Coût total: Aucune donnée

FIN-CERAMICA FAENZA SPA

Italie

• Contribution de l’UE: € 400 137,00
• Adresse: Via Granarolo 177/3 ; 48018 Faenza
• Région: Nord-Est › Emilia-Romagna › Ravenna
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Contact administratif: Maurizio Sottili (Dr.)
• Coût total: Aucune donnée

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG

Allemagne

• Contribution de l’UE: € 380 250,00
• Adresse: SEMINARSTRASSE 2 ; 69117 Heidelberg
• Région: Baden-Württemberg › Karlsruhe › Heidelberg, Stadtkreis
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Joachim Pius Spatz (Prof.)
• Coût total: Aucune donnée

UNIVERSITAT POLITECNICA DE VALENCIA

Espagne

• Contribution de l’UE: € 482 963,00
• Adresse: CAMINO DE VERA SN EDIFICIO 3A ; 46022 Valencia
• Région: Este › Comunitat Valenciana › Valencia/València
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Jose Antonio Perez Garcia (Mr.)
• Coût total: Aucune donnée

BIO-VAC ESPANA SA

Espagne

• Contribution de l’UE: € 138 600,00
• Adresse: BENJAMIN FRANKLIN PARQUE TECNOLOGICO 25 ; 46980 PATERNA-VALENCIA
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Contact administratif: Jose F. Moreno (Mr.)
• Coût total: Aucune donnée

UNIVERSIDAD DE SANTIAGO DE COMPOSTELA

Espagne

• Contribution de l’UE: € 400 500,00
• Adresse: COLEXIO DE SAN XEROME PRAZA DO OBRADOIRO S/N ; 15782 Santiago De Compostela
• Région: Noroeste › Galicia › A Coruña
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Jose Rivas (Prof.)
• Coût total: Aucune donnée

HELMHOLTZ-ZENTRUM DRESDEN-ROSSENDORF EV

Allemagne

• Contribution de l’UE: € 348 594,00
• Adresse: BAUTZNER LANDSTRASSE 400 ; 01328 Dresden
• Région: Sachsen › Dresden › Dresden, Kreisfreie Stadt
• Type d’activité: Research Organisations
• Contact administratif: Rainer Maletti (Dr.)
• Coût total: Aucune donnée

EIDGENOSSISCHE MATERIALPRUFUNGS- UND FORSCHUNGSANSTALT

Suisse

• Contribution de l’UE: € 390 040,00
• Adresse: UEBERLANDSTRASSE 129 ; 8600 Dubendorf
• Région: Schweiz/Suisse/Svizzera › Zürich › Zürich
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Heidi Leutwyler (Ms.)
• Coût total: Aucune donnée

THE UNIVERSITY OF EDINBURGH

Royaume-Uni

• Contribution de l’UE: € 448 021,00
• Adresse: OLD COLLEGE, SOUTH BRIDGE ; EH8 9YL Edinburgh
• Région: Scotland › Eastern Scotland › Edinburgh
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Angela Noble (Ms.)
• Coût total: Aucune donnée

SVEUCILISTE U ZAGREBU MEDICINSKI FAKULTET

Croatie

• Contribution de l’UE: € 210 400,00
• Adresse: SALATA 3 ; 10000 ZAGREB
• Région: Hrvatska › Grad Zagreb › Grad Zagreb
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Mislav Jelic (Dr.)
• Coût total: Aucune donnée

UNIVERSITATSSPITAL BASEL

Suisse

• Contribution de l’UE: € 329 792,00
• Adresse: HEBELSTRASSE 32 ; 4031 Basel
• Région: Schweiz/Suisse/Svizzera › Nordwestschweiz › Basel-Stadt
• Type d’activité: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
• Contact administratif: Caroline Jaussi (Ms.)
• Coût total: Aucune donnée

INVENT SRL

Italie

• Contribution de l’UE: € 356 000,00
• Adresse: VIA DELLA SCROFA 117 ; 00186 ROMA
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Contact administratif: Tommaso Foglia (Dr.)
• Coût total: Aucune donnée

I+ SRL

Italie

• Contribution de l’UE: € 270 000,00
• Adresse: PIAZZA PUCCINI 26 ; 50100 FIRENZE
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Contact administratif: Elena Tamburini (Mrs.)
• Coût total: Aucune donnée

BIODEVICE SYSTEMS SRO

Tchéquie

• Contribution de l’UE: € 174 563,00
• Adresse: BULHARSKA 996 20 ; 10100 Praha
• Région: Česko › Praha › Hlavní město Praha
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Contact administratif: Yuliya Haranava (Dr.)
• Coût total: Aucune donnée

BELARUSSIAN STATE MEDICAL UNIVERSITY

Biélorussie

• Contribution de l’UE: € 285 513,00
• Adresse: Dzerzhinskogo Avenue 83 ; 220116 Minsk
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Vitaly Goranov (Dr.)
• Coût total: Aucune donnée

EXPLORA SRL

Italie

• Contribution de l’UE: € 336 000,00
• Adresse: Via Giacomo Peroni 386 ; 00131 Roma
• Région: Centro (IT) › Lazio › Roma
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Contact administratif: Davide De Lucrezia (Mr.)
• Coût total: Aucune donnée

AvantiCell Science Ltd

Royaume-Uni

• Contribution de l’UE: € 245 401,00
• Adresse: GIBBSYARD BUILDING ; KA6 5HW Ayr
• Région: Scotland › Southern Scotland › South Ayrshire
• Type d’activité: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Contact administratif: Joanna Jane Oliver (Dr.)
• Coût total: Aucune donnée

Central Institute of Orthopedics and Traumatology of Russia

Russie

• Contribution de l’UE: € 100 000,00
• Adresse: Priorov str. 19 ; 127299 Moscow
• Type d’activité: Research Organisations
• Contact administratif: Anton Kurpyakov (Dr.)
• Coût total: Aucune donnée

UNIVERSITY OF BRIGHTON

Royaume-Uni

• Contribution de l’UE: € 330 111,00
• Adresse: LEWES ROAD MITHRAS HOUSE ; BN2 4AT Brighton
• Région: South East (England) › Surrey, East and West Sussex › Brighton and Hove
• Type d’activité: Higher or Secondary Education Establishments
• Contact administratif: Matteo Santin (Dr.)
• Coût total: Aucune donnée