THERAPEUTIC AND PREVENTIVE IMPACT OF NUTRITIONAL LIPIDS ON NEURONAL AND COGNITIVE PERFORMANCE IN AGING, ALZHEIMER’S DISEASE AND VASCULAR DEMENTIA

Project Information

LIPIDIDIET

Grant agreement ID: 211696

Project closed

Start date 1 August 2008

End date 31 March 2015

Funded under

• Specific Programme "Cooperation": Food, Agriculture and Biotechnology

Total cost € 7 995 577,34

EU contribution € 5 899 843,00

Coordinated by

UNIVERSITAT DES SAARLANDES
Germany

Objective

Major objective: It is our aim to develop a lipid based diet that is able to delay or prevent onset of Alzheimer’s disease and related diseases and has a stabilizing effect on cognitive performance in aging. Multiple lines of evidence suggest that there is a large overlap between risk factor of these three diseases. Importantly, there is equally strong evidence that prevention and treatment of these diseases can be efficiently addresses - especially in their first and their priclinical stages - by closely related or identical bio-molecules. Predominantly these molecules appear to belong to the class of lipids which are part of the human diet. However, very often they are consumed in far lesser than recommended amounts. Bearing in mind that all of these diseases have a long pre-clinical phase in which the disease remains undetected specifically designed nutrition may be requirred for effective prevention or for those who already progressed into the first clinical stage of the disease. Moreover, frequently the within the elderly population pathological changes by two or all of these diseases occur in combination thus targeting only one would be insufficient. Taking these aspects into consideration, dietary supplementation, composed to maximize benefit for all three of these in the elderly common diseases, appears to be the most suitable approach to provide a general health perspective improvement for this age group in the EU population.

Fields of science

• medical and health sciences › basic medicine › neurology › dementia › alzheimer
• natural sciences › biological sciences › biochemistry › biomolecules › lipids
• medical and health sciences › health sciences › nutrition

Keywords

• Aging
• Alzheimer's Disease
• Cholesterol
• DHA
• Diet
• Food
• Nutrition

Programme(s)

• FP7-KBBE - Specific Programme "Cooperation": Food, Agriculture and Biotechnology

Topic(s)

• KBBE-2007-2-2-02 - Impact of diet on ageing

Call for proposal

FP7-KBBE-2007-1
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

UNIVERSITAT DES SAARLANDES

• EU contribution: € 1 502 836,00
• Address: CAMPUS ; 66123 Saarbrucken ; Germany
• Region: Saarland › Saarland › Regionalverband Saarbrücken
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Claudia Giehl (Ms.)
• Total cost: No data

Participants (18)

ITA-SUOMEN YLIOPISTO

Finland

• EU contribution: € 925 430,00
• Address: YLIOPISTONRANTA 8 ; 70211 KUOPIO
• Region: Manner-Suomi › Pohjois- ja Itä-Suomi › Pohjois-Savo
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Heikki Tanila (Dr.)
• Total cost: No data

SZEGEDI TUDOMANYEGYETEM

Hungary

• EU contribution: € 272 000,00
• Address: DUGONICS TER 13 ; 6720 Szeged
• Region: Alföld és Észak › Dél-Alföld › Csongrád
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Botond Penke (Prof.)
• Total cost: No data

TEL AVIV UNIVERSITY

Israel

• EU contribution: € 400 408,00
• Address: RAMAT AVIV ; 69978 Tel Aviv
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Lea Pais (Ms.)
• Total cost: No data

STICHTING RADBOUD UNIVERSITEIT

Netherlands

• EU contribution: € 445 600,00
• Address: HOUTLAAN 4 ; 6525 XZ Nijmegen
• Region: Oost-Nederland › Gelderland › Arnhem/Nijmegen
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Fons Verstralen (Mr.)
• Total cost: No data

GOETEBORGS UNIVERSITET

Sweden

• EU contribution: € 285 700,00
• Address: VASAPARKEN ; 405 30 Goeteborg
• Region: Södra Sverige › Västsverige › Västra Götalands län
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Margareta Ahlqwist (Dr.)
• Total cost: No data

DANONE GLOBAL RESEARCH & INNOVATION CENTER BV

Netherlands

• EU contribution: € 480 605,00
• Address: UPPSALALAAN 12 ; 3584 CT Utrecht
• Region: West-Nederland › Utrecht › Utrecht
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: J.H.P. Kersten
• Total cost: No data

KAROLINSKA INSTITUTET

Sweden

• EU contribution: € 147 590,40
• Address: Nobels Vag 5 ; 17177 Stockholm
• Region: Östra Sverige › Stockholm › Stockholms län
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Ulf Edin (Mr.)
• Total cost: No data

FYZIOLOGICKY USTAV AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE (VVI)

Czechia

• EU contribution: € 282 000,00
• Address: VIDENSKA 1083 ; 142 20 Praha 4
• Region: Česko › Praha › Hlavní město Praha
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Vladimír Doležal (Dr.)
• Total cost: No data

VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG

Netherlands

• EU contribution: No data
• Address: De Boelelaan 1105 ; 1081 HV Amsterdam
• Region: West-Nederland › Noord-Holland › Groot-Amsterdam
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Philip Scheltens (Prof.)
• Total cost: No data

RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN

Germany

• EU contribution: € 196 000,00
• Address: REGINA PACIS WEG 3 ; 53113 Bonn
• Region: Nordrhein-Westfalen › Köln › Bonn, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Beate Gieselmann (Ms.)
• Total cost: No data

EURICE EUROPEAN RESEARCH AND PROJECT OFFICE GMBH

Germany

• EU contribution: € 340 050,00
• Address: HEINRICH-HERTZ-ALLEE 1 ; 66386 St Ingbert
• Region: Saarland › Saarland › Saarpfalz-Kreis
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Claudia Giehl (Mrs.)
• Total cost: No data

UNIVERSITAETSKLINIKUM AACHEN

Participation ended

Germany

• EU contribution: No data
• Address: Pauwelsstrasse 30 ; 52074 Aachen
• Region: Nordrhein-Westfalen › Köln › Städteregion Aachen
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Volker Legewie (Mr.)
• Total cost: No data

UNIVERSITATSKLINIKUM HEIDELBERG

Germany

• EU contribution: € 126 372,00
• Address: IM NEUENHEIMER FELD 672 ; 69120 Heidelberg
• Region: Baden-Württemberg › Karlsruhe › Heidelberg, Stadtkreis
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Thorsten Brietz (Mr.)
• Total cost: No data

EBERHARD KARLS UNIVERSITAET TUEBINGEN

Germany

• EU contribution: € 154 496,40
• Address: GESCHWISTER-SCHOLL-PLATZ ; 72074 Tuebingen
• Region: Baden-Württemberg › Tübingen › Tübingen, Landkreis
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Thomas Leyhe (Dr.)
• Total cost: No data

ZENTRALINSTITUT FUER SEELISCHE GESUNDHEIT

Germany

• EU contribution: € 50 973,60
• Address: Square J 5 ; 68159 Mannheim
• Region: Baden-Württemberg › Karlsruhe › Mannheim, Stadtkreis
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Simone Fuchs
• Total cost: No data

KLINIKUM DER UNIVERSITAET REGENSBURG

Germany

• EU contribution: € 58 044,00
• Address: FRANS JOSEF STRAUSS ALLEE 11 ; 93053 Regensburg
• Region: Bayern › Oberpfalz › Regensburg, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Elisabeth Geiger (Ms.)
• Total cost: No data

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

Participation ended

Germany

• EU contribution: No data
• Address: GESCHWISTER SCHOLL PLATZ 1 ; 80539 MUNCHEN
• Region: Bayern › Oberbayern › München, Kreisfreie Stadt
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Kerstin Fischer (Ms.)
• Total cost: No data

STICHTING VU

Netherlands

• EU contribution: € 231 737,60
• Address: DE BOELELAAN 1105 ; 1081 HV Amsterdam
• Region: West-Nederland › Noord-Holland › Groot-Amsterdam
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Philip Scheltens (Prof.)
• Total cost: No data