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Capturing the potential of Gene editing for a sustainable BioEconomy

Deliverables

Preliminary toolbox for gene editing

"Deliverable 2.1 ""Preliminary toolbox for gene editing in plants and microalgae"" is a report describing the up-to-date genome editing toolbox for efficient plant breeding in potato and strain optimalisation in microalgae. The toolbox will comprise state-of-the-art CRISPR/Cas9 based constructs, versatile cloning strategies, optimized DNA delivery and regeneration systems, and bioinformatics methods for the integrated design of guide taking guide efficiency into account as well as knowledge on gene family members. The overall toolbox must permit high precision of editing and minimize unwanted alteration of the edited genomes and to develop edited potato and microalgae. Linked to Task T2.1: Constructing a plant and microalgae gene editing toolbox."

NGT Policy Directions - A policy-based report will provide background and highlight necessary policy directions

"Deliverable 1.6 ""NGT Policy Directions – A policy-based report will provide background and highlight necessary policy directions"" is a report providing distilled policy recommendations to highlight enablers and disablers of NGTs, ethical and current policy and legal issues. Linked to Subtask 1.4.1: Policy Recommendations for the Legislation of NGTs."

Report on biosafety data requirements

"Deliverable 1.1 ""Report on biosafety data requirements"" is a compliance report based on the EU Directive 2001/18 and National Competent Authority requirements for biosafety that will report the risk assessment of 1) GM microalgae based on the QPS (Qualified Presumption of Safety) pipeline, leading to an EFSA risk evaluation; 2) PVY-resistant starch potato following available Competent Authority and EFSA Guidelines. PVY-resistant starch potato. Linked to Task T1.2: Data requirements for biosafety assessment of starch-enhanced, PVY-resistant potatoes and MAA-enhanced microalgae for biobased products under the five governance options"

Initial Communication and Engagement Plan

"Deliverable 4.1 ""Initial Communication and Engagement Plan"" provides the strategy, communication and engagement guidelines with a set of tools and materials to ensure effective communication and a unique project visual identity. Delivered in M6. The deliverable will include the design and use guidelines of: i) website; ii) social media accounts on Facebook, Twitter, LinkedIn, Instagram and YouTube to cover scientific, policy, business and civil society domains and their stakeholder groups’ reach; iii) press releases, advertorials and web banners in various languages and hosted on news websites to promote the key messages and achievements of the project, raise public awareness about the related issues and increase engagement.It will receive input from Task T4.1. Linked to Task T4.2: Participatory approaches to communication, dissemination & stakeholder engagement."

Report on upscaling of WT microalgae strain

"Deliverable 3.1 ""Report on the upscaling of WT Microalgae strain"" will report 1) the case study upscaling results of the WT strain used for developing NGTs, 2) the parameters, 3) adaptations needed when changing to an NGT strain for upscaling. D3.1 is supported by Task T3.4: Cultivation and upscaled production of microalgae."

Publications

Options for regulating new genomic techniques for plants in the European Union

Author(s): Kai Purnhagen, Yasmine Ambrogio, Detlef Bartsch, Dennis Eriksson, Petra Jorasch, Jens Kahrmann, Maximilian Kardung, Alexandra Molitorisova, Alessandro Monaco, Amrit K. Nand, Jörg Romeis, Nils Rostoks, Katharina Unkel & Xenia T. Schneider
Published in: Nature Plants, Issue 9, 2023, ISSN 2055-0278
Publisher: Nature
DOI: 10.1038/s41477-023-01570-2

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