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VACCELERATE - European Corona Vaccine Trial Accelerator Platform

Leistungen

Validation of one or more innovative assays for monitoring the humoral immune response
D5.1 Living data document of all registered COVID-19 vaccine trials

Living data document of all registered COVID19 vaccine trials

VACCELERATE Internal Communication plan finalised
D4.4 Protocols for rapid deployment of collection and transport of specimens in line with the study objectives

Protocols for rapid deployment of collection and transport of specimens in line with the study objectives

Integrate laboratory capability questionnaire into EUVAP
Updated list of standardised data for vaccine trial protocol design
WP13 Final Recruitment Report

Final Recruitment Report

SOP system for vaccine clinical trials
Report on vaccine trial hesitancy completed and disseminated internally in the VACCELERATE network, along stakeholders and available on the website
Phase 2 vaccine trial master protocol templates, one for adults and one for children

Phase 2 vaccine trial master protocol templates one for adults and one for children

Report on use of interoperable data points and common collection protocols/systems

Report on use of interoperable data points and common collection protocolssystems

D7.1 Feasibility assessment of using data standards for vaccine trials (in collaboration with sponsors)

Feasibility assessment of using data standards for vaccine trials in collaboration with sponsors

"Plan for ""Exploitation and Dissemination of Results"" (PEDR)"

Plan for Exploitation and Dissemination of Results PEDR

Terms of Reference document for CTAP finalised, including CTAP members

Terms of Reference document for CTAP finalised including CTAP members

Report on implementation of data management and standards strategy
Lab support strategy to harmonise lab assays in the network
Dissemination of genomic sequencing data from specimens of vaccine trials patients
Standardised protocols for a set of core assays (ELISA and micro-neutralisation assays) for monitoring the humoral immune response and allow comparison across trials and trial sites

Standardised protocols for a set of core assays ELISA and microneutralisation assays for monitoring the humoral immune response and allow comparison across trials and trial sites

Terms of Reference document defining the external Ethics and Scientific Advisory Board operations and responsibilities, including composition of the board & names of the board members

Terms of Reference document defining the external Ethics and Scientific Advisory Board operations and responsibilities, , including composition of the board & names of the board members

D10.4 Registration Number for study from WHO- or ICMJE-approved registry

Registration Number for study from WHO or ICMJEapproved registry

D9.7 Statistical Analysis Plan

Statistical Analysis Plan

Final report on public health questions and emerging issues
D2.4 VACCELERATE Publication Policy

VACCELERATE Publication Policy

Cochrane Qualitative Evidence Synthesis on factors impacting recruitment to pandemic/epidemic vaccine trials

Cochrane Qualitative Evidence Synthesis on factors impacting recruitment to pandemicepidemic vaccine trials

WP12 Midterm Recruitment Report

Midterm Recruitment Report

Report on QMS for vaccine trials
D5.5 Updated report on unanswered COVID-19 vaccines and vaccination priority questions for future trials

Updated report on unanswered COVID19 vaccines and vaccination priority questions for future trials

D7.4 VACCELERATE data management and data sharing plan (DMP)

VACCELERATE data management and data sharing plan DMP

Report on the overall FAIRness of data generated within VACCELERATE
D1.4 Documents and templates for administrative and operational cross-consortium tasks finalised (presentations, letterheads, etc.)

Documents and templates for administrative and operational crossconsortium tasks finalised presentations letterheads etc

D1.3 Templates for annual thematic and financial reporting finalised

Templates for annual thematic and financial reporting finalised

Patient advocacy group needs for volunteers' registries identified

Patient advocacy group needs for volunteers registries identified

Updated report on unanswered COVID-19 vaccines and vaccination priority questions for future trials

Updated report on unanswered COVID19 vaccines and vaccination priority questions for future trials

Terms of Reference documents defining CB and TCB operations and NC responsibilities
D5.8 List of standardised data for vaccine trial protocol design

List of standardised data for vaccine trial protocol design

Annual report on main consortium body activities (topics discussed, recommendations given, decisions made): Coordination Board, PMO, CTAP, E/SAB & TCB Vx year 3
Midterm Recruitment Report
Quality policy
Report on annual consortium meeting year 1
WP13 Registration Number for study from WHO- or ICMJE-approved registry

Registration Number for study from WHO or ICMJEapproved registry

D5.4 Updated report on unanswered COVID-19 vaccines and vaccination priority questions for future trials

Updated report on unanswered COVID19 vaccines and vaccination priority questions for future trials

D5.2 First report on unanswered COVID-19 vaccines and vaccination priority questions for future trials

First report on unanswered COVID19 vaccines and vaccination priority questions for future trials

D5.3 Updated report on unanswered COVID-19 vaccines and vaccination priority questions for future trials

Updated report on unanswered COVID19 vaccines and vaccination priority questions for future trials

Report on annual consortium meeting year 2
ORDP

VACCELERATE data management and data sharing plan DMP

Phase 3 vaccine trial master protocol templates
R-Requirement Nr.7

VACCELERATE data management and data sharing plan DMP

Veröffentlichungen

Perspectives of European Patient Advocacy Groups on Volunteer Registries and Vaccine Trials: VACCELERATE Survey Study.

Autoren: Sophia Themistocleous, Christos D Argyropoulos,Paris Vogazianos, George Shiamakkides, Evgenia Noula, Andria Nearchou, Andreas Yiallouris, Charalampos Filippou, Fiona A Stewart, Markela Koniordou, Ioannis Kopsidas, Helena Hervius Askling, Sirkka Vene, Amandine Gagneux-Brunon,Jana Baranda Prellezo, Elena Álvarez-Barco, Jon Salmanton-García; Janina Leckler, Alan J Macken, Ruth Joanna Davis, Anna Ma
Veröffentlicht in: JMIR Public Health and Surveillance, 2024, ISSN 2369-2960
Herausgeber: JMIR Publications

The Challenges of vaccine trial participation among underserved and hard-to-reach communities: an internal expert consultation of the VACCELERATE consortium

Autoren: Dimitrios Poulimeneas, Markela Koniordou, Dimitra Kousi, Christina Merakou, Ioannis Kopsidas, Grammatiki-Christina Tsopela, Christos Argyropoulos, Sophie C. Themistocleous, George Shiamakkides, Marinos Constantinou, Alexandra Alexandrou, Evgenia Noula, Andria Nearchou, Jon Salmanton-Garcia, Fiona A. Stewart, Sarah Heringer, Kerstin Albus, Elena Alvarez-Barco, Alan Macken, Romina Di Marzo, Catarina
Veröffentlicht in: Vaccines, 2023, ISSN 2076-393X
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines11121784

Enhancing Public Health Communication Regarding Vaccine Trials: Design and Development of the Pan-European VACCELERATE Toolkit

Autoren: Christos D Argyropoulos; Janina Leckler; Jon Salmanton-García; Marinos Constantinou; Alexandra Alexandrou; Sophia Themistocleous; Evgenia Noula; George Shiamakkides; Andria Nearchou; Fiona A Stewart; Kerstin Albus; Markela Koniordou; Ioannis Kopsidas; Orly Spivak ; Margot Hellemans; Greet Hendrickx; Ruth Joanna Davis; Anna Maria Azzini; Paula Valle Simon; Antonio Javier Carcas-
Veröffentlicht in: JMIR Public Health and Surveillance, 2023, ISSN 2369-2960
Herausgeber: JMIR Publications. J. Med. Internet Res.
DOI: 10.2196/44491

A rapid antibody screening haemagglutination test for predicting immunity to SARS-CoV-2 variants of concern

Autoren: Nina Urke Ertesvåg, Julie Xiao, Fan Zhou, Sonja Ljostveit, Helene Sandnes, Sarah Lartey, Marianne Sævik, Lena Hansen, Anders Madsen, Kristin G. I. Mohn, Elisabeth Fjelltveit, Jan Stefan Olofsson, Tiong Kit Tan, Pramila Rijal, Lisa Schimanski, Siri Øyen, Karl Albert Brokstad, Susanna Dunachie, Anni Jämsén, William S. James, Adam C. Harding, Heli Harvala, Dung Nguyen, David Roberts, PHE Virolog
Veröffentlicht in: Communications Medicine, 2022, ISSN 2730-664X
Herausgeber: London Nature Portfolio
DOI: 10.1038/s43856-022-00091-x

A pilot surveillance report of SARS-CoV-2 rapid antigen test results among volunteers in Germany, 1st week of July 2022

Autoren: Jannik Stemler, Jon Salmanton-García, Ben Weise, Christina Többen, Carolin Joisten, Julian Fleig, Oliver A. Cornely on behalf of the VACCELERATE Consortium
Veröffentlicht in: Infection, 2022, ISSN 0300-8126
Herausgeber: Urban und Vogel Medien und Medizin Verlagsgesellschaft mbH
DOI: 10.1007/s15010-022-01931-7

Monkeypox diagnostic and treatment capacity at epidemic onset: A VACCELERATE online survey.

Autoren: Jan Hendrik Grothe; Oliver A. Cornely; Jon Salmanton-García
Veröffentlicht in: Journal of Infection and Public Health, Ausgabe 4, 2022, Seite(n) 043–1046, ISSN 1876-0341
Herausgeber: Elsevier BV
DOI: 10.1016/j.jiph.2022.08.008

VACCELERATE Volunteer Registry: A European study participant database to facilitate clinical trial enrolment

Autoren: Jon Salmanton-García; Fiona A. Stewart; Sarah Heringer; Markela Koniordou; Elena Álvarez-Barco; Christos D. Argyropoulos; Sophia C. Themistocleous; Paula Valle-Simón; Orly Spivak; Lenka Součková; Christina Merakou; Maria Amélia Mendonça; Ruth Joanna Davis; Anna Maria Azzini; Helena H. Askling; Sirkka Vene; Pierre Van Damme; Angela Steinbach; George Shiamakkides; Danila Seidel; Ole F. Olesen
Veröffentlicht in: Vaccine, Ausgabe 1, 2022, Seite(n) 4090-4097, ISSN 0264-410X
Herausgeber: Elsevier BV
DOI: 10.1016/j.vaccine.2022.05.022

Immunogenicity and reactogenicity of a first booster with BNT162b2 or full-dose mRNA-1273: A randomised VACCELERATE trial in adults ≥75 years (EU-COVAT-1)

Autoren: Julia Neuhann, Jannik Stemler, Antonio Carcas, Jesús Frías, Murat Akova, Ullrich Bethe, Sarah Heringer, Jon Salmanton-Garcia, Lea Tischmann, Marouan Zarrouk, Arnd Cüppers, Jan H. Grothe, Alejandro Abner Garcia Leon, Patrick Mallon, Riya Negi, Colette Gaillard, Gurvin Saini, Christine Lammens, An Hotterbeekx, Katherine Loens, Surbhi Malhotra-Kumar, Herman Goosens, Samir Kumar-Singh, Franz König
Veröffentlicht in: Vaccine, 2023, ISSN 0264-410X
Herausgeber: Elsevier BV
DOI: 10.1016/j.vaccine.2023.10.029

The Performances of Three Commercially Available Assays for the Detection of SARS-CoV-2 Antibodies at Different Time Points Following SARS-CoV-2 Infection

Autoren: Heidi Syre, Marius Eduardo Brå Obreque, Ingvild Dalen, Åse Garløv Riis, Åse Berg, Iren Høyland Löhr, Jon Sundal, Lars Kåre Kleppe, May Sissel Vadla, Ole Bernt Lenning, Jan Stefan Olofsson, Kristin Greve-Isdahl Mohn, Camilla Tøndel, Bjørn Blomberg, Mai Chi Trieu, Nina Langeland, Rebecca Jane Cox
Veröffentlicht in: Viruses, Ausgabe 14, 2024, Seite(n) 2196, ISSN 1999-4915
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v14102196

Distinct receptor binding domain IgG thresholds predict protective host immunity across SARS-CoV-2 variants and time

Autoren: Grace Kenny, Sophie O’Reilly, Neil Wrigley Kelly, Riya Negi, Colette Gaillard, Dana Alalwan, Gurvin Saini, Tamara Alrawahneh, Nathan Francois, Matthew Angeliadis, Alejandro Abner Garcia Leon, Willard Tinago, Eoin R. Feeney, Aoife G. Cotter, Eoghan de Barra, Obada Yousif, Mary Horgan, Peter Doran, Jannik Stemler, Philipp Koehler, Rebecca Jane Cox, Donal O’Shea, Ole F. Olesen, Alan Landay, Andre
Veröffentlicht in: Nature Communications, 2023, ISSN 2041-1723
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41467-023-42717-1

Development of a Novel Medium Throughput Flow-Cytometry Based Micro-Neutralisation Test for SARS-CoV-2 with Applications in Clinical Vaccine Trials and Antibody Screening

Autoren: Sophie O’Reilly, Grace Kenny, Tamara Alrawahneh, Nathan Francois, Matthew Angeliadis, Valentin de Masson d’Autume, Alejandro Garcia Leon, Eoin R. Feeney, Obada Yousif, Aoife Cotter, Eoghan de Barra, Mary Horgan, Patrick WG Mallon, Virginie Gautier
Veröffentlicht in: PLOSONE, 2023, ISSN 1932-6203
Herausgeber: Public Library of Science
DOI: 10.1371/journal.pone.0294262

Monkeypox in children and adult women in Europe: Results from a flash VACCELERATE pilot survey

Autoren: Jon Salmanton-García; Jan Grothe; Oliver Cornely
Veröffentlicht in: Enfermedades Infecciosas y Microbiología Clínica, Ausgabe 2, 2022, ISSN 0213-005X
Herausgeber: Ediciones Doyma S.A.
DOI: 10.1016/j.eimc.2022.08.002

Predicting the next pandemic: VACCELERATE ranking of the World Health Organization's Blueprint for Action to Prevent Epidemics

Autoren: Jon Salmanton-García, Pauline Wipfler, Janina Leckler, Pontus Nauclér, Patrick W. Mallon, Patricia C.J.L. Bruijning-Verhagen, Heinz-Joseph Schmitt, Ullrich Bethe, Ole F. Olesen, Fiona A. Stewart, Kerstin Albus, Oliver A. Cornely on behalf of the VACCELERATE Consortium
Veröffentlicht in: Travel Medicine and Infectious Disease, 2024, ISSN 1477-8939
Herausgeber: Elsevier BV
DOI: 10.1016/j.tmaid.2023.102676

Induction of High Levels of Specific Humoral and Cellular Responses to SARS-CoV-2 After the Administration of Covid-19 mRNA Vaccines Requires Several Days

Autoren: Sergio Gil-Manso, Diego Carbonell, Luis López-Fernández, Iria Miguens, Roberto Alonso, Ismael Buño, Patricia Muñoz, Jordi Ochando, Marjorie Pion and Rafael Correa-Rocha
Veröffentlicht in: Frontiers in Immunology, 2021, ISSN 1664-3224
Herausgeber: Lausanne Frontiers Media S.A. 2010
DOI: 10.3389/fimmu.2021.726960

Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial AND Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial

Autoren: Alberto M Borobia, Antonio J Carcas, Mayte Pérez-Olmeda, Luis Castaño, María Jesús Bertran, Javier García-Pérez, Magdalena Campins, Antonio Portolés, María González-Pérez, María Teresa García Morales, Eunate Arana-Arri, Marta Aldea, Francisco Díez-Fuertes, Inmaculada Fuentes, Ana Ascaso, David Lora, Natale Imaz-Ayo, Lourdes E Barón-Mira, Antonia Agustí, Carla Pérez-Ingidua, Agustí
Veröffentlicht in: The Lancet, 2021, ISSN 0140-6736
Herausgeber: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(21)01420-3

Coordination of COVID-19 platform trials in Europe

Autoren: Jacques Demotes, Victoria Charlotte Simensen, Keiko Ueda, Sareema Javaid, Paula Garcia, Burç Aydin, John‑Arne Røttingen
Veröffentlicht in: Trials, 2024, ISSN 1745-6215
Herausgeber: BioMed Central
DOI: 10.1186/s13063-024-08126-5

Development of Potent Cellular and Humoral Immune Responses in Long-Term Hemodialysis Patients After 1273-mRNA SARS-CoV-2 Vaccination

Autoren: Maria Gonzalez-Perez, Maria Montes-Casado, Patricia Conde, Isabel Cervera, Jana Baranda, Marcos J. Berges-Buxeda, Mayte Perez-Olmeda, Rodrigo Sanchez-Tarjuelo, Alberto Utrero-Rico, Daniel Lozano-Ojalvo, Denis Torre, Megan Schwarz, Ernesto Guccione, Carmen Camara, M Rosario Llópez-Carratalá, Emilio Gonzalez-Parra, Pilar Portoles, Alberto Ortiz, Jose Portoles and Jordi Ochando
Veröffentlicht in: Frontiers in Immunology, 2022, ISSN 1664-3224
Herausgeber: Lausanne Frontiers Media S.A. 2010
DOI: 10.3389/fimmu.2022.845882

Efficacy and safety of COVID‐19 vaccines

Autoren: Graña C, Ghosn L, Evrenoglou T, Jarde A, Minozzi S, Bergman H, Buckley BS, Probyn K, Villanueva G, Henschke N, Bonnet H, Assi R, Menon S, Marti M, Devane D, Mallon P, Lelievre JD, Askie LM, Kredo T, Ferrand G, Davidson M, Riveros C, Tovey D, Meerpohl JJ, Grasselli G, Rada G, Hróbjartsson A, Ravaud P, Chaimani A, Boutron I
Veröffentlicht in: Cochrane database of systematic reviews, 2022, ISSN 1469-493X
Herausgeber: John Wiley & Sons Inc.
DOI: 10.1002/14651858.cd015477

Challenges in assessing the immunization status of adults in Germany—lessons from a population‑based VACCELERATE survey on polio vaccination

Autoren: Julia A. Nacov, Jannik Stemler, Jon Salmanton‑García, Louise M. Cremer, Markus Zeitlinger, Patrick W. G. Mallon, Zoi Dorothea Pana, Heinz‑Josef Schmitt, Oliver A. Cornely On behalf of the VACCELERATE Consortium
Veröffentlicht in: Infection, 2024, ISSN 0300-8126
Herausgeber: Urban und Vogel Medien und Medizin Verlagsgesellschaft mbH
DOI: 10.1007/s15010-024-02296-9

Factors that impact on recruitment to vaccine trials in the context of a pandemic or epidemic: a qualitative evidence synthesis (Review)

Autoren: Pauline Meskell, Linda M Biesty, Maura Dowling, Kevin Roche, Elaine Meehan, Claire Glenton, Declan Devane, Sasha Shepperd, Andrew Booth, Rebecca Cox, Xin Hui S Chan, Catherine Houghton
Veröffentlicht in: Cochrane Database of Systematic Reviews, 2023, ISSN 1469-493X
Herausgeber: John Wiley & Sons Inc.
DOI: 10.1002/14651858.mr000065.pub2

Rapid, scalable assessment of SARS-CoV-2 cellular immunity by whole-blood PCR

Autoren: Megan Schwarz, Denis Torre, Daniel Lozano-Ojalvo, Anthony T. Tan, Tommaso Tabaglio, Slim Mzoughi, Rodrigo Sanchez-Tarjuelo, Nina Le Bert, Joey Ming Er Lim, Sandra Hatem, Kevin Tuballes, Carmen Camara, Eduardo Lopez-Granados, Estela Paz-Artal, Rafael Correa-Rocha, Alberto Ortiz, Marcos Lopez-Hoyos, Jose Portoles, Isabel Cervera, Maria Gonzalez-Perez, Irene Bodega-Mayor, Patricia Conde, Jesús Oteo-
Veröffentlicht in: Nature Biotechnology, 2022, ISSN 1087-0156
Herausgeber: Nature Publishing Group
DOI: 10.1038/s41587-022-01347-6

Human Organotypic Airway and Lung Organoid Cells of Bronchiolar and Alveolar Differentiation Are Permissive to Infection by Influenza and SARS-CoV-2 Respiratory Virus

Autoren: Camilla Tvedt Ekanger, Fan Zhou, Dana Bohan, Maria Lie Lotsberg, Maria Ramnefjell, Laurence Hoareau, Gro Vatne Røsland, Ning Lu, Marianne Aanerud, Fabian Gärtner, Pirjo Riitta Salminen, Mariann Bentsen, Thomas Halvorsen, Helge Ræder, Lars A. Akslen, Nina Langeland, Rebecca Cox, Wendy Maury, Linda Elin Birkhaug Stuhr, James B. Lorens, Agnete S. T. Engelsen
Veröffentlicht in: Frontiers in Cellular and Infection Microbiology, Ausgabe 12, 2022, ISSN 2235-2988
Herausgeber: Frontiers Media S. A.
DOI: 10.3389/fcimb.2022.841447

Education pathways and key tasks for research nurses in Europe, results from a VACCELERATE online survey

Autoren: Jon Salmanton-García, Fiona A. Stewart, Pauline Wipfler, Sanne H.I. Hofstraat, Patricia Bruijning-Verhagen, Oliver A. Cornely
Veröffentlicht in: Nurse Education in Practice, 2024, ISSN 1471-5953
Herausgeber: Churchill Livingstone
DOI: 10.1016/j.nepr.2024.103953

No changes in hemostasis after COVID-19–heterologous vaccination schedule: A subanalysis of the phase 2 CombiVacS study

Autoren: Nora V. Butta, Elena G. Arias-Salgado, Elena Monzon Manzano, Paula Acuna, María Teresa Alvarez Román, Antonio Buno-Soto, Juan Carlos Ramos Ramos,, Cristobal Belda-Iniesta, Jesús Frías, Antonio J. Carcas, Lucía Martínez de Soto, Rosa de Miguel Buckley, David Lora, María Teresa García-Morales, Alberto M. Borobia, Jose Ramón Arribas, Víctor Jimenez Yuste on behalf of the CombiVacS Study Gro
Veröffentlicht in: Research and Practice in Thrombosis and Haemostasis, 2023, ISSN 2475-0379
Herausgeber: Elsevier
DOI: 10.1016/j.rpth.2023.100049

A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults ≥75 already vaccinated against SARS-CoV-2 (EU-COVAT-1-AGED): a trial conducted within the VACCELERATE network.

Autoren: Julia M. Neuhann; Jannik Stemler; Antonio Carcas; Jesús Frías-Iniesta; Ullrich Bethe; Sarah Heringer; Lea Tischmann; Marouan Zarrouk; Arnd Cüppers; Franz König; Martin Posch; Oliver A. Cornely
Veröffentlicht in: Trials, Ausgabe 2, 2022, ISSN 1745-6215
Herausgeber: BioMed Central
DOI: 10.1186/s13063-022-06791-y

Dynamics of humoral and cellular immune responses after homologous and heterologous SARS-CoV-2 vaccination with ChAdOx1 nCoV-19 and BNT162b2

Autoren: Emanuel Vogel, Katharina Kocher, Alina Priller, Cho-Chin Cheng, Philipp Steininger, Bo-Hung Liao, Nina Körber, Annika Willmann, Pascal Irrgang, Jürgen Held, Carolin Moosmann, Viviane Schmidt, Stephanie Beileke, Monika Wytopil, Sarah Heringer, Tanja Bauer, Ronja Brockhoff, Samuel Jeske, Hrvoje Mijocevic, Catharina Christa, Jon Salmanton-García, Kathrin Tinnefeld, Christian Bogdan, Sarah Yazici,
Veröffentlicht in: eBioMedicine, 2022, ISSN 2352-3964
Herausgeber: Elsevier BV
DOI: 10.1016/j.ebiom.2022.104294

VACCELERATE Site Network: Real-time definition of clinical study capacity in Europe

Autoren: Jon Salmanton-García, Pauline Wipfler, Paula Valle-Simón, Christina Merakou, Ioannis Kopsidas, Ullrich Bethe, Angela Steinbach, Orly Spivak, Lenka Součková, Maria Amélia Mendonça, Markela Koniordou, Margot Hellemans, Jesus Frías-Iniesta, Ruth Joanna Davis, Imre Barta, Anna Maria Azzini, Helena H. Askling, Christos D. Argyropoulos, Elena Álvarez-Barco, Murat Akova, Marc M.J. Bonten, Miriam
Veröffentlicht in: Vaccine, 2023, ISSN 0264-410X
Herausgeber: Elsevier BV
DOI: 10.1016/j.vaccine.2023.05.006

Factors that impact on recruitment to vaccine trials during a pandemic or epidemic: a qualitative evidence synthesis [protocol]

Autoren: Pauline Meskell, Linda M Biesty, Maura Dowling, Elaine Meehan, Claire Glenton, Declan Devane, Sasha Shepperd, Andrew Booth, Rebecca Cox, Xin Hui S Chan, Catherine Houghton
Veröffentlicht in: Cochrane database of systematic reviews, 2022, ISSN 1469-493X
Herausgeber: John Wiley & Sons Inc.
DOI: 10.1002/14651858.mr000065

Maintenance of Potent Cellular and Humoral Immune Responses in Long-Term Hemodialysis Patients after 1273-mRNA SARS-CoV-2 Vaccination

Autoren: Maria Gonzalez-Perez; Jana Baranda; Marcos J. Berges-Buxeda; Patricia Conde; Mayte Pérez-Olmeda; Daniel Lozano-Ojalvo; Carmen Cámara; Maria del Rosario Llópez-Carratalá; Emilio Gonzalez-Parra; Pilar Portolés; Alberto Ortiz; Jose Portoles; Jordi Ochando
Veröffentlicht in: Pharmaceuticals, 2023, ISSN 1424-8247
Herausgeber: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ph16040574

Vaccination rates in Europe are not associated with online media intensity

Autoren: Catarina Luís, Veronica Romina Di Marzo, Mandeep Kaur, Christos D. Argyropoulos, Declan Devane, Fiona Anne Stewart, George Antoniou, Greet Hendrickx, Helena Hervius Askling, Margot Hellemans, Miriam Cohen, Orly Spivak, Pierre Van Damme, Rebecca Jane Cox, Sirkka Vene, Sofie Sibia, Zoi Dorothea Pana and Ole F. Olesen, on behalf of VACCELERATE Consortium
Veröffentlicht in: Journal of Science Communication (JCOM), Ausgabe approx. 7 issues per year, 2022, ISSN 1824-2049
Herausgeber: Scuola Internazionale Superiore di Studi Avanzati (SISSA)
DOI: 10.22323/2.21050205

Durable immune responses after BNT162b2 vaccination in home-dwelling old adults

Autoren: Lena Hansen; Karl Albert Brokstad; Amit Bansal; Fan Zhou; Geir Bredholt; Therese Bredholt Onyango; Helene Heitmann Sandnes; Rebecca Elyanow; Anders Madsen; Mai-Chi Trieu; Marianne Sævik; Hanne Søyland; Jan Stefan Olofsson; Juha Vahokoski; Nina Urke Ertesvåg; Elisabeth Berg Fjelltveit; Shahin Shafiani; Camilla Tøndel; Heidi Chapman; Ian Kaplan; Kristin G.I. Mohn; Nina Langeland; Rebecca Jane Co
Veröffentlicht in: Vaccine: X, 2023, ISSN 2590-1362
Herausgeber: Elsevier Ltd.
DOI: 10.1016/j.jvacx.2023.100262

Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals

Autoren: Daniel Lozano-Ojalvo, Carmen Camara, Eduardo Lopez-Granados, Pilar Nozal, Lucía del Pino-Molina, Luz Yadira Bravo-Gallego, Estela Paz-Artal, Marjorie Pion, Rafael Correa-Rocha, Alberto Ortiz, Marcos Lopez-Hoyos, Marta Erro Iribarren, Jose Portoles, Maria Pilar Rojo-Portoles, Gloria Ojeda, Isabel Cervera, Maria Gonzalez-Perez, Irene Bodega-Mayor, Maria Montes-Casado, Pilar Portoles, Mayte Perez-Ol
Veröffentlicht in: Cell Reports, 2021, ISSN 2211-1247
Herausgeber: Cell Press
DOI: 10.1016/j.celrep.2021.109570

Heterologous prime–boost vaccination with ChAdOx1 nCoV-19 and BNT162b2

Autoren: Matthias Tenbusch, Sofie Schumacher, Emanuel Vogel, Alina Priller, Jürgen Held, Philipp Steininger, Stephanie Beileke, Pascal Irrgang, Ronja Brockhoff, Jon Salmanton-García, Kathrin Tinnefeld, Hrvoje Mijocevic, Kilian Schober, Christian Bogdan, Sarah Yazici, Percy Knolle, Oliver A. Cornely, Klaus Überla, Ulrike Protzer on behalf of the DZIF-Vaccelerate-CoVaKo study team
Veröffentlicht in: The Lancet Infectious diseases, 2021, ISSN 1473-3099
Herausgeber: The Lancet Publishing Group
DOI: 10.1016/s1473-3099(21)00420-5

Performance and validation of an adaptable multiplex assay for detection of serologic response to SARS-CoV-2 infection or vaccination

Autoren: Grace Kenny, Riya Negi, Sophie O'Reilly, Alejandro Garcia-Leon, Dana Alalwan, Colette Marie Gaillard, Gurvin Saini, Rosana Inzitari, Eoin R. Feeney, Obada Yousif, Aoife G Cotter, Eoghan de Barra, Corinna Sadlier, Fiona Crispie, Peter Doran, Virginie Gautier, Patrick W.G. Mallon, on behalf of the All Ireland Infectious Diseases cohort study
Veröffentlicht in: Journal of Immunological Methods, 2022, ISSN 0022-1759
Herausgeber: Elsevier BV
DOI: 10.1016/j.jim.2022.113345

Cellular immunity Assay (CI)

Autoren: Ochando, Jordi; VACCELERATE (Projekt)
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2022
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Infor-mations-zentrum Lebens-wissen-schaften
DOI: 10.4126/frl01-006434987

Preparation of PBMCs

Autoren: VACCELERATE (Projekt); Kelly, Christine; Garcia Leon, Alejandro Abner
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2021
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Infor-mations-zentrum Lebens-wissen-schaften
DOI: 10.4126/frl01-006434993

Anti-Sars-Cov-2 (Spike, Nucleocapsid and RBD) IgG Protocol for MSD Platform

Autoren: VACCELERATE (Projekt); Garcia Leon, Alejandro Abner
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2021
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Infor-mations-zentrum Lebens-wissen-schaften

Whole blood processing

Autoren: VACCELERATE (Projekt); Kelly, Christine; Garcia Leon, Alejandro Abner
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2021
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Infor-mations-zentrum Lebens-wissen-schaften
DOI: 10.4126/frl01-006434995

Development of a Novel Medium Throughput Flow-Cytometry Based Micro-Neutralisation Test for SARS-CoV-2 with Applications in Clinical Vaccine Trials and Antibody Screening

Autoren: Sophie O’Reilly, Grace Kenny, Tamara Alrawahneh, Nathan Francois, Matthew Angeliadis, Valentin de Masson d’Autume, Alejandro Garcia Leon, Eoin R. Feeney, Obada Yousif, Aoife Cotter, Eoghan de Barra, Mary Horgan, Patrick WG Mallon, Virginie Gautier
Veröffentlicht in: medRxiv, 2023
Herausgeber: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.01.18.23284713

Additional file 2 of A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults ≥75 already vaccinated against SARS-CoV-2 (EU-COVAT-1-AGED): a trial conducted within the VACCELERATE network

Autoren: Neuhann, Julia M.; Stemler, Jannik; Carcas, Antonio; Frías-Iniesta, Jesús; Bethe, Ullrich; Heringer, Sarah; Tischmann, Lea; Zarrouk, Marouan; Cüppers, Arnd; König, Franz; Posch, Martin; Cornely, Oliver A.
Veröffentlicht in: Trials, Ausgabe 1, 2022
Herausgeber: BioMed Central
DOI: 10.6084/m9.figshare.21303517

Sample Handling

Autoren: VACCELERATE (Projekt); Kelly, Christine; Garcia Leon, Alejandro Abner
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2021
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Infor-mations-zentrum Lebens-wissen-schaften
DOI: 10.4126/frl01-006434994

Education Pathways and Key Tasks for Research Nurses in Europe, Results from a VACCELERATE Online Survey

Autoren: Jon Salmanton-García, Fiona A. Stewart, Pauline Wipfler, Sanne H.I. Hofstraat, Patricia Bruijning-Verhagen, Oliver A. Cornely, on behalf of the VACCELERATE consortium
Veröffentlicht in: medRxiv, 2023
Herausgeber: Elsevier

Additional file 1 of A multinational, phase 2, randomised, adaptive protocol to evaluate immunogenicity and reactogenicity of different COVID-19 vaccines in adults ≥75 already vaccinated against SARS-CoV-2 (EU-COVAT-1-AGED): a trial conducted within the VACCELERATE network

Autoren: Neuhann, Julia M.; Stemler, Jannik; Carcas, Antonio; Frías-Iniesta, Jesús; Bethe, Ullrich; Heringer, Sarah; Tischmann, Lea; Zarrouk, Marouan; Cüppers, Arnd; König, Franz; Posch, Martin; Cornely, Oliver A.
Veröffentlicht in: Trials, Ausgabe 2, 2022
Herausgeber: BioMed Central
DOI: 10.6084/m9.figshare.21303514

Immunogenicity and Reactogenicity of a First Booster with NT162b2or Full-Dose mRNA-1273: A Randomised VACCELERATE Trial in Adults ≥75 Years (EU-COVAT-1)

Autoren: Julia Neuhann, Jannik Stemler, Antonio Carcas, Jesús Frías, Murat Akova, Ullrich Bethe, Sarah Heringer, Jon Salmanton-Garcia, Lea Tischmann, Marouan Zarrouk, Arnd Cüpers, Jan H. Grothe, Alejandro Abner Garcia Leon, Patrick Mallon, Riya Negi, Colette Gaillard, Gurvin Saini, Christine Lammens, An Hotterbeekx, Katherine Loens, Surbhi Malhotra-Kumar, Herman Goosens, Samir Kumar-Singh, Franz König,
Veröffentlicht in: Preprints with THE LANCET, 2023
Herausgeber: SSRN - Elsevier

Haemagglutination assay (HAT)

Autoren: Cox, Rebecca; VACCELERATE (Projekt)
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2021
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Infor-mations-zentrum Lebens-wissen-schaften
DOI: 10.4126/frl01-006434989

Collection and Handling of Biological Materials

Autoren: VACCELERATE (Projekt); Kelly, Christine; Garcia Leon, Alejandro Abner
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2021
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Informationszentrum Lebenswissenschaften
DOI: 10.4126/frl01-006434990

Immunogenicity, reactogenicity and safety of a second booster with BNT162b2 or full-dose mRNA-1273: a randomised VACCELERATE trial in adults ≥75 years (EU-COVAT-1-AGED Part B)

Autoren: Jannik Stemler, Lusine Yeghiazaryan, Christoph Stephan, Kirsten Greve-Isdahl Mohn, Antonio-José Carcas-Sansuan, Esperanza Romero Rodriguez, José Moltó, Itziar Vergara Mitxeltorena, Tobias Welte, Birutė Zablockienė, Murat Akova, Ullrich Bethe, Sarah Heringer, Jon Salmanton-García, Julia Jeck, Lea Tischmann, Marouan Zarrouk, Arnd Cüppers, Lena M. Biehl, Jan Grothe, Sibylle C. Mellinghoff, Jul
Veröffentlicht in: medRxiv, 2023
Herausgeber: Elsevier

Current evidence regarding treatment of hospitalized Covid-19 patients. Summary of main results: April 2022

Autoren: The COVID-NMA team
Veröffentlicht in: Ausgabe 4, 2022
Herausgeber: Zenodo
DOI: 10.5281/zenodo.6452030

Flow Cytometry based-Live SARS-CoV-2 Micro-Neutralisation assay

Autoren: Gautier, Virginie; VACCELERATE (Projekt)
Veröffentlicht in: Fachrepositorium Lebenswissenschaften, Ausgabe 1, 2021
Herausgeber: Deutsche Zentralbibliothek für Medizin (ZB MED) - Infor-mations-zentrum Lebens-wissen-schaften
DOI: 10.4126/frl01-006434991

Rechte des geistigen Eigentums

EUVAP

Antrags-/Publikationsnummer: DE 302021211078
Datum: 2021-03-03

Vaccelerate

Antrags-/Publikationsnummer: DE 302021226584
Datum: 2022-03-11

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