Novel avenues of action for a hallmark disordered protein of Parkinson's disease

Project Information

SYN-CHARGE

Grant agreement ID: 101023654

DOI 10.3030/101023654

Project closed

EC signature date 14 April 2021

Start date 1 February 2022

End date 31 January 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 219 312,00

EU contribution € 219 312,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Deciphering the Alphabet of Disorder-Glu and Asp Act Differently on Local but Not Global Properties

Author(s): Mette Ahrensback Roesgaard; Jeppe E. Lundsgaard; Estella A. Newcombe; Nina L. Jacobsen; Francesco Pesce; Emil E. Tranchant; Søren Lindemose; Andreas Prestel; Rasmus Hartmann-Petersen; Kresten Lindorff-Larsen; Birthe B. Kragelund
Published in: Biomolecules, Issue Volume 12; Issue 10, 2022, Page(s) 1426, ISSN 2218-273X
Publisher: MDPI
DOI: 10.1101/2022.08.25.505250

Monomeric α‐synuclein activates the plasma membrane calcium pump

Author(s): Antoni Kowalski, Cristine Betzer, Sigrid Thirup Larsen, Emil Gregersen, Estella A Newcombe, Montaña Caballero Bermejo, Viktor Wisniewski Bendtsen, Jorin Diemer, Christina V Ernstsen, Shweta Jain, Alicia Espiña Bou, Annette Eva Langkilde, Lene N Nejsum, Edda Klipp, Robert Edwards, Birthe B Kragelund, Poul Henning Jensen, Poul Nissen
Published in: The EMBO Journal, Issue Volume 42; Issue 23, 2023, Page(s) e111122, ISSN 1460-2075
Publisher: EMBO Press
DOI: 10.15252/embj.2022111122

How phosphorylation impacts intrinsically disordered proteins and their function

Author(s): Estella A. Newcombe; Elise Delaforge; Rasmus Hartmann-Petersen; Karen Skriver; Birthe B. Kragelund
Published in: Essays in Biochemistry, Issue Volume 66, Issue 7, 2022, Page(s) 901–913, ISSN 1744-1358
Publisher: Portland Press
DOI: 10.1042/ebc20220060

Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins

Author(s): Francesco Pesce; Estella A. Newcombe; Pernille Seiffert; Emil E. Tranchant; Johan G. Olsen; Christy R. Grace; Birthe B. Kragelund; Kresten Lindorff-Larsen
Published in: Biophysical Journal, Issue Volume 122; Issue 2, 2023, Page(s) 310-321, ISSN 1542-0086
Publisher: Elsevier
DOI: 10.1101/2022.06.11.495732