Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic: ORCHESTRA

Rezultaty

Report on feasibility of enrolling vaccinated HCWs in phase 4 vaccine trials

Results of the feasibility study will be conducted to assess whether the pooled cohort of vaccinated HCWs can be used as population for phase-4 (post-marketing) COVID-19 vaccine trials. This deliverable will be under the responsibility of UNIBO and INSP.

Project Management Guidelines

Guidelines elaborated ad hoc for the ORCHESTRA project with information relating to both scientific and administrative management of the project

Systematic review of the literature on determinants of COVID-19 manifestation/ progression
Report on assessment of intra-host viral dynamics and immunity half-life
First report on serology in fragile populations

A report of serology results will be provided for at least 2,000 patients in the fragile population cohorts in the prospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Algorithms for guiding therapeutic decisions for COVID-19 patients

The algorithms will include evidence from retrospective and prospective cohorts and systematic review for guiding therapeutic decisions for COVID-19 patients

First interim risk analysis of breakthrough infection

First interim risk analysis of breakthrough infection, with regard to vaccination manufacturer, post-vaccination titer, last 3 monthly titer, viral strain

Communication and dissemination strategy plan and website online
Quality and kinetic of long-term immune response to COVID-19 vaccination in fragile patients (interim report)

Assessment of humoral and cellular immune response at 6 and 12 months after vaccination

First report on immunity analysis from prospective cohorts (COVID-19, vaccinated and not vaccinated)

A first report of immunity results will be provided for at least 2,500 individuals in the prospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Quality and kinetic of early immune response to COVID-19 vaccination in fragile patients

Assessment of humoral and cellular immune response in-between vaccination doses and at 3 months after vaccination

Identification of break-through infections in population-based cohorts
Report on viral loads, viral genome sequences on prospective cohorts (preliminary report)

A final report of the viral loads and viral genome sequences will be provided for a total of 10,000 patients combining retrospective and prospective analyses. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR

Report on viral genome sequences and serology in case of breakthrough infections

In case of breakthrough infections after vaccination, samples collected from these patients will be analysed using serology and viral genome sequencing. Results will be reported as soon as they become available. Routinely updated. The publication of the deliverable for personal individual data will follow the relevant laws and regulation andnotably the GDPR.

Report on estimates of intervention effects using compartment model
Final report of 6-month follow up by clinical, immunological and virological features
Results of analysis of determinants of COVID-19 and their longitudinal changes among HCWs

Summary of determinants of diseases and their change based on the epidemiological scenario

Report on the serological immune responses of non-vaccinated infected, vaccinated, and breakthrough infected individuals
Preliminary report on seroprevalence in EU countries
Final analysis of serology results after vaccination

Results of serological immune function of HCWs after vaccination by type of vaccination. Final deliverable version at M12 (3-6 months after vaccination). This deliverable will be under the responsibility of UNIBO and LMU.

Interim analysis of serology results after vaccination

Preliminary results of serological immune function of HCWs after vaccination by type of vaccination. First deliverable version at M7 (2-6 weeks after vaccination). This deliverable will be under the responsibility of UNIBO and LMU.

Report on risk associated with socio-economic factors
Report on serology analysis of retrospective COVID-19 cohorts

A report of the serology results will be provided for the 1,500 patients in the retrospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Final risk analysis of breakthrough infection

Final risk analysis of breakthrough infection, with regard to vaccination manufacturer, post-vaccination titer, last 3 monthly titer, viral strain

Immunological response in vaccinated and not vaccinated HCWs (temporal trend) final

Final results of serological immune function of HCWs after vaccination by type of vaccination. This deliverable will be under the responsibility of UNIBO and UNIVR.

Report on cytokine chemokine analysis in COVID-19 patients from retrospective cohorts

A report of the cytokine/chemokine results will be provided for the 1,500 patients in the retrospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Report on serology analysis including long-term sequelae and natural immunity (WP2)

A report of serology results will be provided for at least 2,000 patients focusing on long-term sequelae in the prospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Final report on cellular immunity analysis for prospective cohorts (COVID-19, vaccinated and not vaccinated)

A second and final report of cellular immunity results will be provided for a total of 5,000 individuals (including the ones reported for D6.8) in the prospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Incidence of breakthrough infections

Incidence of breakthrough infections in the HCWs cohorts

Report on impact of pandemic on socio-economic indicators
Report on estimates of intervention effects using individual-based models
Report on dataset of genome-wide methylation patterns

The final results of the genome-wide methylation analysis of a total of 1,500 patients will be completed. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Final report of 12-month follow up by clinical, immunological and virological features
Report on cytokine chemokine analysis in COVID-19 patients (including long-term sequelae)

A report of cytokine chemokine results will be provided for COVID-19 patients focused on long-term sequelae in the prospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Report on viral loads, viral genome sequences of retrospective cohorts

A report of the results of the viral (variant) genome sequencing and viral loads will be provided for the 1,500 patients in the retrospective study. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Cohort Builder and Dashboard online
Social media accounts created and accredited
First regular graphics visualized

Anonymous dataset for the public published

This deliverable will include an explicit confirmation that the data used in the project is publicly available can be freely used for the purpose of the project.

Call for first science challenge based on anonymized project dataset
Automated emails service for stakeholders
Dataset of human genome sequencing of patients with COVID-19 from retrospective cohorts

The sequencing of the human genome for 500 patients in the retrospective study will be completed. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Dataset of 16S rRNA sequencing of retrospective cohorts

16S rRNA gene sequencing data from patients with varying degrees of COVID-19 will be completed for a maximum number of 1,500 patients. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

Dataset of human genomic sequencing outcome of patients from prospective COVID-19 cohorts

The sequencing of the human genome for 1,000 patients in the prospective study will be completed. The publication of the deliverable for personal individual data will follow the relevant laws and regulation and notably the GDPR.

In silico model of vaccination strategies

Publikacje

Retrospective analysis of SARS-CoV-2 omicron invasion over delta in French regions in 2021–22: a status-based multi-variant model

Autorzy: Thomas Haschka, Elisabeta Vergu, Benjamin Roche, Chiara Poletto, Lulla Opatowski
Opublikowane w: BMC Infectious Diseases, Numer 22, 2022, Strona(/y) 815, ISSN 1471-2334
Wydawca: BioMed Central
DOI: 10.1186/s12879-022-07821-5

Vaccination Confidence among Healthcare Workers: Results from Two Anamnestic Questionnaires Adopted in the COVID-19 and Influenza Campaign

Autorzy: Mansour I, Collatuzzo G, De Pasquale V, Mirra I, Ciocan C, Godono A, Pira E, Boffetta P
Opublikowane w: Vaccines, Numer 10(11), 2022, Strona(/y) 1835, ISSN 2076-393X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines10111835

SARS-CoV-2 Breakthrough Infections: Incidence and Risk Factors in a Large European Multicentric Cohort of Health Workers

Autorzy: Stefano Porru; Maria Grazia Lourdes Monaco; Gianluca Spiteri; Angela Carta; Maria Diletta Pezzani; Giuseppe Lippi; Davide Gibellini; Evelina Tacconelli; Ilaria Dalla Vecchia; Emma Sala; Emanuele Sansone; Giuseppe De Palma; Carlo Bonfanti; Massimo Lombardo; Luigina Terlenghi; Enrico Pira; Ihab Mansour; Maurizio Coggiola; Catalina Ciocan; Alessandro Godono; Adonina Tardon; Marta-Maria Rodriguez-Suar
Opublikowane w: Vaccines, Numer 10(8), 2022, Strona(/y) 1193, ISSN 2076-393X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines10081193

Studying temporal titre evolution of commercial SARS-CoV-2 assays reveals significant shortcomings of using BAU standardization for comparison

Autorzy: Inge Kroidl, Simon Winter, Raquel Rubio-Acero, Abhishek Bakuli, Christof Geldmacher, Tabea M. Eser, Flora Déak, Sacha Horn, Anna Zielke, Mohamed I. M. Ahmed, Paulina Diepers, Jessica Guggenbühl, Jonathan Frese, Jan Bruger, Kerstin Puchinger, Jakob Reich, Philine Falk, Alisa Markgraf, Heike Fensterseifer, Ivana Paunovic, Angelika Thomschke, Michael Pritsch, Friedrich Riess, Elmar Saathoff, KoCo19
Opublikowane w: Virology Journal, Numer September 2023, 200, 2023, ISSN 1743-422X
Wydawca: BioMed Central
DOI: 10.1186/s12985-023-02167-z

Effectiveness of prevention of SARS-CoV-2 transmission among unvaccinated Italian healthcareworkers

Autorzy: Collatuzzo G, Mansour I, Ciocan C, Ditano G, Godono A, Rossello P, Coggiola M, Pira E, Boffetta P, Working Group On Sars-Cov-Prevention
Opublikowane w: La Medicina del Lavoro, Numer 113(6), 2022, ISSN 0025-7818
Wydawca: Mattioli 1885 SpA
DOI: 10.23749/mdl.v113i6.13577

ISO/TS 21564:2019- based Evaluation of a Semantic Map between Variables in the ISARIC Freestanding Follow Up Survey and ORCHESTRA Studies

Autorzy: Eugenia Rinaldi, Sylvia Thun, Caroline Stellmach
Opublikowane w: Journal of Medical Systems, Numer 47(115), 2023, ISSN 0148-5598
Wydawca: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10916-023-02012-4

Evaluation of the kinetics of antibody response to COVID-19 vaccine in solid organ transplant recipients: the prospective, multicentre ORCHESTRA cohort

Autorzy: Giannella M, Righi E, Pascale R, Rinaldi M, Caroccia N, Gamberini C, Palacios-Baena ZR, Caponcello G, Morelli MC, Tamè M, Busutti M, Comai G, Potena L, Salvaterra E, Feltrin G, Cillo U, Gerosa G, Cananzi M, Piano S, Benetti E, Burra P, Loy M, Furian L, Zaza G, Onorati F, Carraro A, Gastaldon F, Nordio M, Kumar-Singh S, Abedini M, Boffetta P, Rodríguez-Baño J, Lazzarotto T, Viale P, Tacconelli E
Opublikowane w: Microorganisms, Numer 10(5), 2022, ISSN 2076-2607
Wydawca: MDPI
DOI: 10.3390/microorganisms10051021

Diagnostic Accuracy of a Rapid SARS-CoV-2 Antigen Test Among People Experiencing Homelessness: A Prospective Cohort and Implementation Study

Autorzy: Pasquale De Nardo; Maela Tebon; Alessia Savoldi; Nicola Soriolo; Elisa Danese; Denise Peserico; Matteo Morra; Elisa Gentilotti; Gulser Caliskan; Pierpaolo Marchetti; Riccardo Cecchetto; Annarita Mazzariol; Giuseppe Verlato; Davide Gibellini; Evelina Tacconelli
Opublikowane w: Infectious Diseases and Therapy, Numer 12, 2023, Strona(/y) 1073-1082, ISSN 2193-8229
Wydawca: OMICS International
DOI: 10.1007/s40121-023-00787-0

High sera levels of SARS-CoV-2 N antigen are associated with death in hospitalized COVID-19 patients

Autorzy: Houssem Redha Chenane, Guillaume Lingas, Reyene Menidjel, Cédric Laouenan, Sarah Tubiana, Diane Descamps, Quentin Le Hingrat, Laurent Abel, Jérémie Guedj, Surbhi Malhotra, Samir Kumar-Singh, Benoit Visseaux, Jade Ghosn, Charlotte Charpentier, Samuel Lebourgeois, the French COVID Cohort Study Group
Opublikowane w: Journal of Medical Virology, Numer 95(11), 2023, ISSN 0146-6615
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/jmv.29247

A Systematic Review of Predictor Composition, Outcomes, Risk of Bias, and Validation of Coronavirus Disease 2019 (COVID-19) Prognostic Scores

Autorzy: Katharina S. Appel, Ramsia Geisler, Daniel Maier, Olga Miljukov, Sina M. Hopff, J. Janne Vehreschild
Opublikowane w: Clinical Infectious Diseases, Numer ciad618, 2023, ISSN 1537-6591
Wydawca: Oxford University Press
DOI: 10.1093/cid/ciad618

Serological response after SARS-CoV2 vaccination in healthcare workers: a multicenter study

Autorzy: Visci G, Zunarelli C, Mansour I, Porru S, De Palma G, Duval X, Monaco MGL, Spiteri G, Carta A, Lippi G, Verlato G, Sansone E, Sala E, Lombardo M, Abedini M, Violante F, Boffetta P.
Opublikowane w: La Medicina del Lavoro, Numer 113(2), 2022, ISSN 0025-7818
Wydawca: Mattioli 1885 SpA
DOI: 10.23749/mdl.v113i2.13017

Determinants of anti-S immune response at 6 months after COVID-19 vaccination in a multicentric European cohort of healthcare workers – ORCHESTRA project

Autorzy: Giulia Collatuzzo, Giovanni Visci, Francesco S. Violante, Stefano Porru, Gianluca Spiteri, Maria Grazia Lourdes Monaco, Francesca Larese Fillon, Corrado Negro, Christian Janke, Noemi Castelletti, Giuseppe De Palma, Emanuele Sansone, Dana Mates, Silvia Teodorescu, Eleonóra Fabiánová, Jana Bérešová, Luigi Vimercati, Silvio Tafuri, Mahsa Abedini, Giorgia Ditano, Shuffield S. Asafo, Paolo Boffe
Opublikowane w: Frontiers in Immunology, Numer September 2022, Volume 13, 2022, ISSN 1664-3224
Wydawca: Frontiers Media S.A
DOI: 10.3389/fimmu.2022.986085

The Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf): Risk Factors and Determinants of Immune Response in Healthcare Workers

Autorzy: Christina Reinkemeyer; Yeganeh Khazaei; Maximilian Weigert; Marlene Hannes; Ronan Le Gleut; Michael Plank; Simon Winter; Ivan Noreña; Theresa Meier; Lisa Xu; Raquel Rubio-Acero; Simon Wiegrebe; Thu Giang Le Thi; Christiane Fuchs; Katja Radon; Ivana Paunovic; Christian Janke; Andreas Wieser; Helmut Küchenhoff; Michael Hoelscher; Noemi Castelletti
Opublikowane w: Viruses, Numer 15(7), 2023, Strona(/y) 1574, ISSN 1999-4915
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/v15071574

Enhanced Spike-specific, but attenuated Nucleocapsid-specific T cell responses upon SARS-CoV-2 breakthrough versus non-breakthrough infections

Autorzy: Mohamed Ibraheem Mahmoud Ahmed; Paulina Diepers; Christian Janke; Michael Plank; Tabea M. Eser; Raquel Rubio-Acero; Anna Fuchs; Olga Baranov; Noemi Castelletti; Inge Kroidl; Laura Olbrich; Bernadette Bauer; Danni Wang; Martina Prelog; Johannes G. Liese; Christina Reinkemeyer; Michael Hoelscher; Philipp Steininger; Klaus Überla; Andreas Wieser; Christof Geldmacher
Opublikowane w: Frontiers in Immunology, Numer December 2022, 13:13:1026473, 2022, ISSN 1664-3224
Wydawca: Frontiers Media S.A
DOI: 10.3389/fimmu.2022.1026473

SARS-CoV-2 Breakthrough Infections in Health Care Workers: An Italian Retrospective Cohort Study on Characteristics, Clinical Course and Outcomes

Autorzy: Luigi De Maria; Stefania Sponselli; Antonio Caputi; Pasquale Stefanizzi; Antonella Pipoli; Gianmarco Giannelli; Giuseppe Delvecchio; Silvio Tafuri; Francesco Inchingolo; Giovanni Migliore; Francesco Paolo Bianchi; Paolo Boffetta; Luigi Vimercati
Opublikowane w: Journal of Clinical Medicine; Volume 12; Numer 2; Pages: 628, Numer 12(2), 2023, Strona(/y) 628, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm12020628

Integrative modelling of reported case numbers and seroprevalence reveals time-dependent test efficiency and infection rates

Autorzy: Lorenzo Contento; Noemi Castelletti; Elba Raimúndez; Elba Raimúndez; Le Gleut R; Yannik Schaelte; Paul Stapor; Hinske Lc; Michael Hoelscher; Andreas Wieser; Katja Radon; Christiane Fuchs; Jan Hasenauer; Jan Hasenauer
Opublikowane w: Volume 43, June 2023, 100681, Numer 34, 2023, ISSN 1755-4365
Wydawca: Elsevier BV
DOI: 10.1016/j.epidem.2023.100681

SARS-CoV-2 mRNA Vaccine Response in People Living with HIV According to CD4 Count and CD4/CD8 Ratio

Autorzy: Vergori A, Tavelli A, Matusali G, Azzini AM, Augello M, Mazzotta V, Pellicanò GF, Costantini A, Cascio A, De Vito A, Marconi L, Righi E, Sartor A, Pinnetti C, Maggi F, Bai F, Lanini S, Piconi S, Levy Hara G, Marchetti G, Giannella M, Tacconelli E, d'Arminio Monforte A, Antinori A, Cozzi-Lepri A, On Behalf Of The Vax-Icona-Orchestra Study
Opublikowane w: Vaccines, Numer 11(11), 2023, Strona(/y) 1664, ISSN 2076-393X
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/vaccines11111664

Predictors of clinical evolution of SARS-CoV-2 infection in hematological patients: a systematic review and meta-analysis

Autorzy: Elena Carrara, Elisa Razzaboni, Anna Maria Azzini, Maria Elena De Rui, Mariana Nunes Pinho Guedes, Anna Gorska, Maddalena Giannella, Linda Bussini, Michele Bartoletti, Federica Arbizzani, Zaira R. Palacios-Baena, Giulia Caponcello, Natalia Maldonado, Jesús Rodríguez-Baño, Carlo Visco, Mauro Krampera, Evelina Tacconelli
Opublikowane w: Hematological Oncology, Numer 41(1), 2022, Strona(/y) 16-25, ISSN 0278-0232
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hon.3084

Broad T Cell Targeting of Structural Proteins After SARS-CoV-2 Infection: High Throughput Assessment of T Cell Reactivity Using an Automated Interferon Gamma Release Assay

Autorzy: Isabel Brand, Leonard Gilberg, Jan Bruger, Mercè Garí, Andreas Wieser, Tabea M. Eser, Jonathan Frese, Mohamed I. M. Ahmed, Raquel Rubio-Acero, Jessica M. Guggenbuehl Noller, Noemi Castelletti, Jana Diekmannshemke, Sophie Thiesbrummel, Duc Huynh, Simon Winter, Inge Kroidl, Christiane Fuchs, Michael Hoelscher, Julia Roider, Sebastian Kobold, Michael Pritsch, Christof Geldmacher on behalf of the Ko
Opublikowane w: Frontiers in Immunology, Numer May 2021, Volume 12, 2021, Strona(/y) Frontiers, ISSN 1664-3224
Wydawca: Frontiers
DOI: 10.3389/fimmu.2021.688436

ORCHESTRA project in Romania - a prospective occupational cohort to study the impact of COVID-19 pandemic on health care workers

Autorzy: Dana Mateș, Violeta Claudia Calotă, Cătălin Alexandru Staicu, Lavinia Călugăreanu, Mădălina Ipate, Michaela Mărgineanu, Marina Ruxandra Oțelea, Ovidiu Persecă, Felicia Steliana Popescu, Agripina Rașcu, Silvia Teodorescu, Georgeta Botin, Angelica Voinoiu, Andra Neamțu
Opublikowane w: Romanian Journal of Occupational Medicine, Numer vol 72 (1) dec 2021, 2021, Strona(/y) 54-58, ISSN 2601-0828
Wydawca: De Gruyter Poland
DOI: 10.2478/rjom-2021-0008

Host immunological responses facilitate development of SARS-CoV-2 mutations in patients receiving monoclonal antibody treatments

Autorzy: Akshita Gupta; Angelina Konnova; Mathias Smet; Matilda Berkell; Alessia Savoldi; Matteo Morra; Vincent Van averbeke; Fien H.R. De Winter; Denise Peserico; Elisa Danese; An Hotterbeekx; Elda Righi; Pasquale De Nardo; Evelina Tacconelli; Surbhi Malhotra-Kumar; Samir Kumar-Singh
Opublikowane w: The journal of clinical investigation, Numer 133(6), 2023, ISSN 0021-9738
Wydawca: American Society for Clinical Investigation
DOI: 10.1172/jci166032

Clinical efficacy of different monoclonal antibody regimens among non-hospitalised patients with mild to 1moderate COVID-19at high risk for disease progression: a prospective cohort study

Autorzy: Alessia Savoldi, Matteo Morra, Pasquale De Nardo, Anna Maria Cattelan, Massimo Mirandola, Vinicio Manfrin, Piergiorgio Scotton, Maria Teresa Giordani, Lucio Brollo, Sandro Panese, Massimiliano Lanzafame, Giovanna Scroccaro, Matilda Berkell, Giuseppe Lippi, Angelina Konnova, Mathias Smet, Surbhi Malhotra-Kumar, Samir Kumar-Singh, Evelina Tacconelli, and the mAb Working Group
Opublikowane w: European Journal of Clinical Microbiology & Infectious Diseases, 2022, ISSN 0934-9723
Wydawca: Springer Verlag
DOI: 10.1007/s10096-022-04464-x

SARS-CoV-2 Infections, Re-Infections and Clinical Characteristics: A Two-Year Retrospective Study in a Large University Hospital Cohort of Vaccinated Healthcare Workers

Autorzy: De Maria L, Delvecchio G, Sponselli S, Cafaro F, Caputi A, Giannelli G, Stefanizzi P, Bianchi FP, Stufano A, Tafuri S, Lovreglio P, Boffetta P, Vimercati L.
Opublikowane w: Journal of Clinical Medicine, Numer 12(21), 2023, Strona(/y) 6800, ISSN 2077-0383
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm12216800

Usefulness and Limitations of Anti-S IgG Assay in Detecting Previous SARS-CoV-2 Breakthrough Infection in Fully Vaccinated Healthcare Workers

Autorzy: Gianluca Spiteri, Maria Grazia Lourdes Monaco, Gulser Caliskan, Angela Carta, Maria Diletta Pezzani, Giuseppe Lippi,Davide Gibellini, Giuseppe Verlato, Stefano Porru
Opublikowane w: Diagnostics, 2022, ISSN 2078-2489
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/diagnostics12092152

Determinants of persistence of symptoms and impact on physical and mental wellbeing in Long COVID: A prospective cohort study

Autorzy: Elda Righi, Massimo Mirandola, Fulvia Mazzaferri, Giuditta Dossi, Elisa Razzaboni, Amina Zaffagnini, Federico Ivaldi, Alessandro Visentin, Lorenza Lambertenghi, Cinzia Arena, Claudio Micheletto, Davide Gibellini, Evelina Tacconelli
Opublikowane w: Journal of Infection, Numer 84 (4), 2022, Strona(/y) 566-572, ISSN 0163-4453
Wydawca: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.jinf.2022.02.003

Clinical outcome in solid organ transplant recipients affected by COVID-19 compared to general population: a systematic review and meta-analysis

Autorzy: Gatti M, Rinaldi M, Bussini L, Bonazzetti C, Pascale R, Pasquini Z, Faní F, Pinho Guedes MN, Azzini AM, Carrara E, Palacios-Baena ZR, Caponcello G, Reyna-Villasmil E, Tacconelli E, Rodríguez-Baño J, Viale P, Giannella M; ORCHESTRA study group
Opublikowane w: Clinical Microbiology and Infection, 2022, ISSN 1198-743X
Wydawca: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2022.02.039

The impact of SARS-CoV-2 on healthcare workers of a large University Hospital in the Veneto Region: risk of infection and clinical presentation in relation to different pandemic phases and some relevant determinants

Autorzy: Filippo Liviero, Anna Volpin, Patrizia Furlan, Monica Battistella, Alessia Broggio, Laura Fabris, Francesco Favretto, Paola Mason, Silvia Cocchio, Claudia Cozzolino, Vincenzo Baldo, Angelo Moretto, Maria Luisa Scapellato
Opublikowane w: Frontiers in Public Health, Numer 11, 2023, ISSN 2296-2565
Wydawca: Frontiers Media SA
DOI: 10.3389/fpubh.2023.1250911

Labor market participation and depression during the COVID-19 pandemic among young adults (18 to 30 years): A nationally representative study in France

Autorzy: Maria Melchior; Aline-Marie Florence; Camille Davisse-Paturet; Bruno Falissard; Cédric Galéra; Jean-Baptiste Hazo; Cécile Vuillermoz; Josiane Warszawski; Fallou Dione; Alexandra Rouquette
Opublikowane w: Frontiers in Public Health, Numer 10, 2022, ISSN 2296-2565
Wydawca: Frontiers Media SA
DOI: 10.3389/fpubh.2022.904665

Stronger and durable SARS-CoV-2 immune response to mRNA vaccines in 5–11 years old children with prior COVID-19

Autorzy: Costanza Di Chiara, Anna Cantarutti, Maria Raffaella Petrara, Francesco Bonfante, Elisa Benetti, Riccardo Boracchini, Luca Bosa, Francesco Carmona, Chiara Cosma, Nicola Cotugno, Marthe Le Prevost, Giorgia Martini, Alessandra Meneghel, Matteo Pagliari, Paolo Palma, Elena Ruffoni, Annachiara Zin, Anita De Rossi, Carlo Giaquinto, Daniele Donà, Andrea Padoan
Opublikowane w: Vaccine, Numer 41(2), 2024, Strona(/y) 263-270, ISSN 0264-410X
Wydawca: Elsevier BV
DOI: 10.1016/j.vaccine.2023.12.006

Protective SARS-CoV-2 Antibody Response in Children With Inflammatory Bowel Disease

Autorzy: Luca Bosa, Costanza Di Chiara, Paola Gaio, Chiara Cosma, Andrea Padoan, Sandra Cozzani, Giorgio Perilongo, Mario Plebani, Carlo Giaquinto, Daniele Donà and Mara Cananzi
Opublikowane w: Frontiers in Pediatrics, Numer 10, 2022, ISSN 2296-2360
Wydawca: Frontiers
DOI: 10.3389/fped.2022.815857

Higher risk, higher protection: COVID-19 risk among immigrants in France—results from the population-based EpiCov survey

Autorzy: Anne Gosselin, Josiane Warszawski, Nathalie Bajos, for the EpiCov Study Group
Opublikowane w: European Journal of Public Health, Numer 32(4), 2022, ISSN 1101-1262
Wydawca: Oxford University Press
DOI: 10.1093/eurpub/ckac046

Predictive model for BNT162b2 vaccine response in cancer patients based on cytokines and growth factors

Autorzy: Angelina Konnova; Fien HR De Winter; Akshita Gupta; Lise Verbruggen; An Hotterbeekx; Matilda Berkell; Laure-Anne Teuwen; Greetje Vanhoutte; Bart Peeters; Silke Raats; Isolde Van der Massen; Sven De Keersmaecker; Yana Debie; Manon Huizing; Pieter Pannus; Kristof Y Neven; Kevin K Ariën; Geert A. Martens; Marc Van Den Bulcke; Ella Roelant; Isabelle Desombere; Sébastien Anguille; Zwi Berneman; Maria
Opublikowane w: Frontiers in Immunology, Numer 13, 2022, ISSN 1664-3224
Wydawca: Frontiers Media S.A
DOI: 10.3389/fimmu.2022.1062136

Use of health care services among people with Covid-19 symptoms in the first pandemic peak in France

Autorzy: Jeanna-Eve, Pousson; Léna, Silberzan; Florence, Jusot; Laurence, Meyer; Josiane, Warszawski; Nathalie, Bajos
Opublikowane w: PLOS ONE, 2022, ISSN 1932-6203
Wydawca: Public Library of Science
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Using machine learning to predict antibody response to SARS-CoV-2 vaccination in solid organ transplant recipients: the multicentre ORCHESTRA cohort

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Autorzy: Fulvia Mazzaferri, Massimo Mirandola, Alessia Savoldi, Pasquale De Nardo,Matteo Morra, Maela Tebon, Maddalena Armellini, Giulia De Luca, Lucrezia Calandrino, Lolita Sasset, Denise D'Elia, Emanuela Sozio, Elisa Danese, Davide Gibellini, Isabella Monne, Giovanna Scroccaro, Nicola Magrini, Annamaria Cattelan, Carlo Tascini, MANTICO Working Group, Evelina Tacconelli
Opublikowane w: eLife, 2022, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/elife.79639

International Clinical Research Data Ecosystem: From Data Standardization to Federated Analysis

Autorzy: Eugenia Rinaldi, Chiara Dellacasa, Miroslav Puskaric, Thomas Osmo, Anna Gorska, Caroline Stellmach
Opublikowane w: Studies in Health Technology and Informatics, Numer Volume 309, 2023, Strona(/y) 133-134, ISSN 1879-8365
Wydawca: IOS Press
DOI: 10.3233/shti230757

Assessment of neutralizing antibody responses after natural SARS-CoV-2 infection and vaccination in Congolese individuals

Autorzy: Francine Ntoumi; Armel Landry Batchi-Bouyou; Jean Claude Djontu; Jeannhey Christevy Vouvoungui; Claujens Chastel Mapanguy Mfoutou; Line Lobaloba Ingoba; Jiré Séphora Mougany; Kamal Rauchelvy Boumpoutou; Steve Diafouka-kietela; Raoul Ampa
Opublikowane w: BMC Infectious Diseases, Numer 22, 2022, ISSN 1471-2334
Wydawca: BioMed Central
DOI: 10.1186/s12879-022-07593-y

Perceived Psychological Impact on Children and Parents of Experiencing COVID-19 Infection in One or More Family Members

Autorzy: Paola Costenaro; Costanza Di Chiara; Valentina Boscolo; Alessia Barbieri; Alice Tomasello; Anna Cantarutti; Sandra Cozzani; Cecilia Liberati; Serenella Oletto; Carlo Giaquinto; Daniele Donà
Opublikowane w: Children, Numer 9(9), 2022, Strona(/y) 1370, ISSN 2227-9067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
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The COVID HOME study research protocol: Prospective cohort study of non-hospitalised COVID-19 patients

Autorzy: Tami A, van der Gun BTF, Wold KI, Vincenti-González MF, Veloo ACM, Knoester M, Harmsma VPR, de Boer GC, Huckriede ALW, Pantano D, Gard L, Rodenhuis-Zybert IA, Upasani V, Smit J, Dijkstra AE, de Haan JJ, van Elst JM, van den Boogaard J, O' Boyle S, Nacul L, Niesters HGM, Friedrich AW.
Opublikowane w: PLOS ONE, 2022, ISSN 1932-6203
Wydawca: Public Library of Science
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Global Association of COVID-19 Pandemic Measures with Cancer Treatment: A Systematic Review and Meta-Analysis

Autorzy: Federica Teglia; Marco Angelini; Giulia Casolari; Laura Astolfi; Paolo Boffetta
Opublikowane w: Cancers, Numer 14(22), 2022, Strona(/y) 5490, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
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Cross-sectional survey evaluating the psychological impact of the COVID-19 vaccination campaign in patients with cancer: The VACCINATE study

Autorzy: Daniela Tregnago,Alice Avancini,Lorenzo Belluomini,Ilaria Trestini,Marco Sposito,Jessica Insolda,Federica Bianchi,Teodoro Sava,Chiara Gaiani,Lidia Del Piccolo,Valentina Guarnieri,Giuseppe Verlato,Ahmad Tfaily,Roberta Vesentini,Serena Zuliani,Sara Pilotto,Michele Milella
Opublikowane w: PLOS One, Numer 19(1), 2024, ISSN 1932-6203
Wydawca: Public Library of Science
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The incidence and risk factors of selected drug prescriptions and outpatient care after SARS-CoV-2 infection in low-risk subjects: a multicenter population-based cohort study

Autorzy: Carlo Gagliotti1, Federico Banchelli, Angela De Paoli, Rossella Buttazzi, Elena Narne, Enrico Ricchizzi, Elena Schievano, Stefania Bellio, Gisella Pitter, Michele Tonon, Lorenzo Maria Canziani, Maurizia Rolli, Evelina Tacconelli, Elena Berti,‡ Francesca Russo, Maria Luisa Moro
Opublikowane w: Frontiers in Public Health, Numer Volume 11, 2023, ISSN 2296-2565
Wydawca: Frontiers Media SA
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Risk and severity of SARS-CoV-2 infection in breast cancer patients undergoing a structured infection screening program at the University and Hospital Trust of Verona

Autorzy: S.Zanelli, E. Fiorio, I. Zampiva, F. Zacchi, G. Borghesan, E. Giontella1V. Parolin, P.Biondani, S. Zuliani, M. V. Dieci, E. Mioranza, M. Zorzi, M. Conti, D. Gibellini, G. Verlato, M. Milella
Opublikowane w: Annals of Oncology, Numer 33(6), 2022, Strona(/y) 661-663, ISSN 0923-7534
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Mucosal response of inactivated and recombinant COVID-19 vaccines in Congolese individuals

Autorzy: Freisnel H. Mouzinga, Constanze Heinzel, Abel Lissom, Andrea Kreidenweiss, Armel L. Batchi-Bouyou, Jacques D. Mbama Ntabi, Jean C. Djontu, Etienne Ngumbi, Peter G. Kremsner, Rolf Fendel, Francine Ntoumi
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Clinical Impact of Monoclonal Antibodies in the Treatment of High-Risk Patients with SARS-CoV-2 Breakthrough Infections: The ORCHESTRA Prospective Cohort Study

Autorzy: Alessia Savoldi, Matteo Morra, Alessandro Castelli, Massimo Mirandola, Matilda Berkell, Mathias Smet, Angelina Konnova, Elisa Rossi, Salvatore Cataudella, Pasquale De Nardo, Elisa Gentilotti, Akshita Gupta, Daniele Fasan, Enrico Gibbin, Filippo Cioli Puviani, Jan Hasenauer, Roy Gusinow, Adriana Tami, Samir Kumar-Singh, Surbhi Malhotra-Kumar, mAb Orchestra Working Group, Evelina Tacconelli
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Determinants of Anti-S Immune Response at 12 Months after SARS-CoV-2 Vaccination in a Multicentric European Cohort of Healthcare Workers-ORCHESTRA Project

Autorzy: Ludovica Leomanni , Giulia Collatuzzo , Emanuele Sansone , Emma Sala , Giuseppe De Palma, Stefano Porru, Gianluca Spiteri, Maria Grazia Lourdes Monaco, Daniela Basso, Sofia Pavanello, Maria Luisa Scapellato, Francesca Larese Filon, Luca Cegolon, Marcella Mauro, Vittorio Lodi, Tiziana Lazzarotto, Ivan Noreña , Christina Reinkemeyer, Le Thi Thu Giang, Eleonóra Fabiánová, Jozef Strhársky, Marco
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Effect of a Fourth Dose of mRNA Vaccine and of Immunosuppression in Preventing SARS-CoV-2 Breakthrough Infections in Heart Transplant Patients

Autorzy: Marco Masetti; Maria Francesca Scuppa; Alessio Aloisio; Laura Giovannini; Laura Borgese; Stefania Manno; Beatrice Tazza; Renato Pascale; Cecilia Bonazzetti; Natascia Caroccia; Mario Sabatino; Giosafat Spitaleri; Pierluigi Viale; Maddalena Giannella; Luciano Potena
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Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
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ORCHESTRA: Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2

Autorzy: Gabriella Scipione, Chiara Dellacasa, Elisa Rossi
Opublikowane w: Cineca HPC Report 2021-2022, Numer annual, 2022, Strona(/y) 39-40, ISBN 9788886037440
Wydawca: Grafiche Zanini

ORCHESTRA: Connecting European Cohorts to Increase Common and Effective Response to SARS-CoV-2 Pandemic

Autorzy: Mattia D’Antonio, Chiara Dellacasa, Maurizio Ortali, Elisa Rossi, Gabriella Scipione
Opublikowane w: Cineca HPC Report 2020, Numer annual, 2022, Strona(/y) 31, ISBN 9788886037426
Wydawca: Grafiche Zanini

Projects in “-omics” science field

Autorzy: Elisa Rossi, Silvia Gioiosa, Beatrice Chiavarini, Giuseppa Muscianisi
Opublikowane w: Cineca HPC Report 2022-2023, Numer annual, 2023, Strona(/y) 38, ISBN 9788886037464
Wydawca: Grafiche Zanini

Immunological biomarkers of COVID-19: response to vaccination and monoclonal antibody treatments in immunocompromised patients

Autorzy: Angelina Konnova
Opublikowane w: PhD dissertation, Numer 1, 2023, Strona(/y) 1-193
Wydawca: University of Antwerp

Development, Validation, and Accuracy of ORCHESTRA Emotional Exhaustion Questionnaire

Autorzy: R.K. Gan, P. Arcos González, M. Rodríguez‑Suárez, G. Fernández Tardón, A. Zerbo, D. Mates, E. Fabiánová, M. Otelea, A.Tardon
Opublikowane w: Gaceta Sanitaria, Numer 37(S1), 2023, Strona(/y) S187, ISSN 1578-1283
Wydawca: Elsevier B.V.

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