Autism Innovative Medicine Studies – 2 – Trials | AIMS-2-TRIALS | Project | Results | H2020 | CORDIS

Rezultaty

Second report of Engagement, Dissemination and Communication Plan

Present and report results of Engagement and Communication Plan

First report of Engagement, Dissemination and Communication Plan

Present and report results of Engagement and Communication Plan

Fifth report of Engagement, Dissemination and Communication Plan

Present and report results of Engagement and Communication Plan

Press Release

Co-LEAD KCL, ROCHE Press Release

AIMS-2-TRIALS Website launched

AIMS-2-TRIALS Website

Third report of Engagement, Dissemination and Communication Plan

Present and report results of Engagement and Communication Plan

Sixth report of Engagement, Dissemination and Communication Plan

Present and report results of Engagement and Communication Plan

Fourth report of Engagement, Dissemination and Communication Plan

Present and report results of Engagement and Communication Plan

Clinical Trial Network (CTN) established and trained to GCP standards and ‘trial ready’ with a single point of contact

CTN

Submission of a validated Biomarker to regulation qualification

Key deliverable

Results of economic modelling and simulations
Identify reasons for prior trial failures in autism. Publish white paper with ATN

Publish white paper with ATN

Outcome measures: Midterm recruitment report

Outcome measures

SynaG PMS/NRXN Midterm recruitment report

SynaG PMS/NRXN

RCT1: Midterm recruitment report

RCT1 Midterm recruitment report

LEAP:Midterm recruitment report

LEAP

Clinical Trials network in Europe
Meta-regressions of predictors of placebo response in ASD
SOPs finalised and e-data management systems established

SOPs

Submission of a panel of stratification markers for regulatory approval
First stakeholder meeting and presentation of outcome to EU and UN Parliaments

First stakeholder meeting

PIP: Midterm recruitment report;

PIP

Neonatal: Midterm recruitment report

Neonatal

Infant: Midterm recruitment report

Infant

SPS -AIMS Midterm recruitment report

SPSAIMS

Epilepsy: Midterm recruitment report

Midterm report

RCT1: Report on status of posting results

RCT1 Report on status of posting results

Fetal: Midterm recruitment report

Fetal

Draft of Data Management plan

The plan will describe how data will be managed in the project and how it will contribute to the Open Research Data Pilot. The plan will be updated over the duration of the project according to the dissemination level of the corresponding deliverables.

Midterm Data Management Plan

updated version available for the interim review

Meta-analysis of placebo-controlled pharmacological and dietary supplement trials in ASD and meta-analytic database (electronic database)

electronic database

Publikacje

Role of cortical excitatory/inhibitory imbalance in autism spectrum disorders from a symptom severity trajectories framework: a study protocol

Autorzy: Ciarrusta, J., Christiaens, D., Fitzgibbon, S. P., Dimitrova, R., Hutter, J., Hughes, E., Duff, E., Price, A. N., Cordero-Grande, L., Tournier, J. D., Rueckert, D., Hajnal, J. V, Arichi, T., McAlonan, G., Edwards, A. D., & Batalle, D.
Opublikowane w: BMC Psychiatry, Numer 23, 2021, ISSN 1471-244X
Wydawca: BioMed Central
DOI: 10.1186/s12888-023-04695-y

Inclusive education in the European Union: A fuzzy-set qualitative comparative analysis of education policy for autism

Autorzy: van Kessel, Robin; Hrzic, Rok; Cassidy, Sarah; Brayne, Carol; Baron-Cohen, Simon; Roman-Urrestarazu, Andres; Czabanowska, Katarzyna
Opublikowane w: Social Work in Public Health, Numer 39, 2021, ISSN 1937-1918
Wydawca: Haworth Press Inc.
DOI: 10.21203/rs.3.rs-36514/v1

Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

Autorzy: Martine Hoogman, Daan Rooij, Marieke Klein, Premika Boedhoe, Iva Ilioska, Ting Li, Yash Patel, Merel C. Postema, Yanli Zhang‐James, Evdokia Anagnostou, Celso Arango, Guillaume Auzias, Tobias Banaschewski, Claiton H. D. Bau, Marlene Behrmann, Mark A. Bellgrove, Daniel Brandeis, Silvia Brem, Geraldo F. Busatto, Sara Calderoni, Rosa Calvo, Francisco X. Castellanos, David Coghill, Annette Conzelmann
Opublikowane w: Human Brain Mapping, 2019, ISSN 1065-9471
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25029

Mapping brain asymmetry in health and disease through the ENIGMA consortium

Autorzy: Xiang‐Zhen Kong, Merel C. Postema, Tulio Guadalupe, Carolien Kovel, Premika S. W. Boedhoe, Martine Hoogman, Samuel R. Mathias, Daan Rooij, Dick Schijven, David C. Glahn, Sarah E. Medland, Neda Jahanshad, Sophia I. Thomopoulos, Jessica A. Turner, Jan Buitelaar, Theo G. M. Erp, Barbara Franke, Simon E. Fisher, Odile A. Heuvel, Lianne Schmaal, Paul M. Thompson, Clyde Francks
Opublikowane w: Human Brain Mapping, 2020, ISSN 1065-9471
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25033

Leveraging epigenetics to examine differences in developmental trajectories of social attention: A proof-of-principle study of DNA methylation in infants with older siblings with autism

Autorzy: Anna Gui, Emily J.H. Jones, Chloe C.Y. Wong, Emma Meaburn, Baocong Xia, Greg Pasco, Sarah Lloyd-Fox, Tony Charman, Patrick Bolton, Mark H. Johnson
Opublikowane w: Infant Behavior and Development, Numer 60, 2020, Strona(/y) 101409, ISSN 0163-6383
Wydawca: Elsevier BV
DOI: 10.1016/j.infbeh.2019.101409

Atypical measures of diffusion at the gray-white matter boundary in autism spectrum disorder in adulthood

Autorzy: Anke Bletsch,Tim Schäfer,Caroline Mann,Derek S. Andrews,Eileen Daly,Maria Gudbrandsen,Amber N. V. Ruigrok,Robert Dallyn,Rafael Romero-Garcia,Meng-Chuan Lai,Michael V. Lombardo,Michael C. Craig,John Suckling,Edward T. Bullmore,Simon Baron-Cohen,the MRC AIMS Consortium,Declan G. M. Murphy,Flavio Dell'Acqua,Christine Ecker
Opublikowane w: Human Brain Mapping, 2020, ISSN 1065-9471
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/hbm.25237

Global motion processing in infants’ visual cortex and the emergence of autism

Autorzy: Irzam Hardiansyah, Pär Nyström, Mark J. Taylor, Sven Bölte, Angelica Ronald & Terje Falck-Ytter
Opublikowane w: Communications Biology, Numer 6, 2023, ISSN 2399-3642
Wydawca: Springer Nature
DOI: 10.1038/s42003-023-04707-3

The Vulnerability Experiences Quotient (VEQ): A Study of Vulnerability, Mental Health and Life Satisfaction in Autistic Adults

Autorzy: Sarah Griffiths, Carrie Allison, Rebecca Kenny, Rosemary Holt, Paula Smith, Simon Baron‐Cohen
Opublikowane w: Autism Research, Numer 12/10, 2019, Strona(/y) 1516-1528, ISSN 1939-3806
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/aur.2162

Meta-analytic evidence of differential prefrontal and early sensory cortex activity during non-social sensory perception in autism

Autorzy: Jassim, Nazia; Baron-Cohen, Simon; Suckling, John
Opublikowane w: Neuroscience and Biobehavioral Reviews, Numer 13, 2021, ISSN 0149-7634
Wydawca: Pergamon Press Ltd.
DOI: 10.5281/zenodo.7049822

Fetal anogenital distance using ultrasound

Autorzy: Ezra Aydin, Rosemary Holt, Daren Chaplin, Rebecca Hawkes, Carrie Allison, Gerald Hackett, Topun Austin, Alex Tsompanidis, Lidia Gabis, Shimrit Ilana Ziv, Simon Baron‐Cohen
Opublikowane w: Prenatal Diagnosis, 2019, ISSN 0197-3851
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/pd.5459

Points to consider when initiating clinical investigations in autistic paediatric populations–A White Paper

Autorzy: Lindsay M. Ham, Hannah Staunton, Jan Michael Schulz, Julian Tillmann, Dietmar Volz, Lorraine Murtagh, Christopher Chatham, Eoin C. O'Connor, Stormy Chamberlain, Philipp Schoenenberger, Gahan Pandina, Paul Wang, Martien J.H. Kas, Celso Arango, Declan Murphy
Opublikowane w: European Neuropsychopharmacology, Numer 86, 2024, Strona(/y) 35-42, ISSN 0924-977X
Wydawca: Elsevier BV
DOI: 10.1016/j.euroneuro.2024.05.011

Placebo response in pharmacological and dietary supplement trials of autism spectrum disorder (ASD): systematic review and meta-regression analysis.

Autorzy: Spyridon Siafis, Oğulcan Çıray, Johannes Schneider-Thoma, Irene Bighelli, Marc Krause, Alessandro Rodolico, Anna Ceraso, Giacomo Deste, Maximilian Huhn, David Fraguas, Dimitris Mavridis, Tony Charman, Declan G. Murphy, Mara Parellada, Celso Arango and Stefan Leucht
Opublikowane w: Molecular Autism, Numer 11, 2020, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-020-00372-z

How mental health care should change as a consequence of the COVID-19 pandemic

Autorzy: Carmen Moreno, Til Wykes, Silvana Galderisi, Merete Nordentoft, Nicolas Crossley, Nev Jones, Mary Cannon, Christoph U Correll, Louise Byrne, Sarah Carr, Eric Y H Chen, Philip Gorwood, Sonia Johnson, Hilkka Kärkkäinen, John H Krystal, Jimmy Lee, Jeffrey Lieberman, Carlos López-Jaramillo, Miia Männikkö, Michael R Phillips, Hiroyuki Uchida, Eduard Vieta, Antonio Vita, Celso Arango
Opublikowane w: The Lancet Psychiatry, Numer 7/9, 2020, Strona(/y) 813-824, ISSN 2215-0366
Wydawca: Elsevier Limited
DOI: 10.1016/S2215-0366(20)30307-2

Cerebellar Atypicalities in Autism?

Autorzy: Charles Laidi, Dorothea L. Floris, Julian Tillmann, Yannis Elandaloussi, Mariam Zabihi, Tony Charman, Thomas Wolfers, Sarah Durston, Carolin Moessnang, Flavio Dell’Acqua, Christine Ecker, Eva Loth, Declan Murphy, Simon Baron-Cohen, Jan K. Buitelaar, Andre F. Marquand, Christian F. Beckmann, Vincent Frouin, Marion Leboyer, Edouard Duchesnay, Pierrick Coupé, Josselin Houenou, and the EU-AIMS LEAP
Opublikowane w: Biological Psychiatry, Numer 92, 2022, Strona(/y) 674-682, ISSN 0006-3223
Wydawca: Elsevier BV
DOI: 10.1016/j.biopsych.2022.05.020

Real-time monitoring of infant theta power during naturalistic social experiences

Autorzy: Elena Throm, Anna Gui, Rianne Haartsen, Pedro F. da Costa, Robert Leech, Emily J.H. Jones
Opublikowane w: Developmental Cognitive Neuroscience, Numer 63, 2023, Strona(/y) 101300, ISSN 1878-9293
Wydawca: Elsevier BV
DOI: 10.1016/j.dcn.2023.101300

Sensory Processing Sensitivity in the context of Environmental Sensitivity: A critical review and development of research agenda

Autorzy: Corina U. Greven, Francesca Lionetti, Charlotte Booth, Elaine N. Aron, Elaine Fox, Haline E. Schendan, Michael Pluess, Hilgo Bruining, Bianca Acevedo, Patricia Bijttebier, Judith Homberg
Opublikowane w: Neuroscience & Biobehavioral Reviews, Numer 98, 2019, Strona(/y) 287-305, ISSN 0149-7634
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2019.01.009

Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project

Autorzy: Carolin Moessnang, Sarah Baumeister, Julian Tillmann, David Goyard, Tony Charman, Sara Ambrosino, Simon Baron-Cohen, Christian Beckmann, Sven Bölte, Carsten Bours, Daisy Crawley, Flavio Dell’Acqua, Sarah Durston, Christine Ecker, Vincent Frouin, Hannah Hayward, Rosemary Holt, Mark Johnson, Emily Jones, Meng-Chuan Lai, Michael V. Lombardo, Luke Mason, Marianne Oldenhinkel, Antonio Persico, Anton
Opublikowane w: Molecular Autism, Numer 11/1, 2020, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-020-0317-x

The developing brain structural and functional connectome fingerprint

Autorzy: Ciarrusta, J., Christiaens, D., Fitzgibbon, S. P., Dimitrova, R., Hutter, J., Hughes, E., Duff, E., Price, A. N., Cordero-Grande, L., Tournier, J. D., Rueckert, D., Hajnal, J. V, Arichi, T., McAlonan, G., Edwards, A. D., & Batalle, D.
Opublikowane w: Developmental Cognitive Neuroscience, Numer 55, 2022, ISSN 1878-9293
Wydawca: Elsevier BV
DOI: 10.1016/j.dcn.2022.101117

Developmental Paths to Anxiety in an Autism-Enriched Infant Cohort: The Role of Temperamental Reactivity and Regulation

Autorzy: Mutluhan Ersoy, Tony Charman, Greg Pasco, Ewan Carr, Mark H. Johnson, Emily J. H. Jones
Opublikowane w: Journal of Autism and Developmental Disorders, 2020, ISSN 0162-3257
Wydawca: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10803-020-04734-7

Subcellular Sorting of Neuregulins Controls the Assembly of Excitatory-Inhibitory Cortical Circuits

Autorzy: Exposito-Alonso, David; Osório, Catarina; Bernard, Clémence; Pascual-García, Sandra; del Pino, Isabel; Marin, Oscar; Rico, Beatriz
Opublikowane w: eLife, Numer 42, 2021, ISSN 2050-084X
Wydawca: eLife Sciences Publications
DOI: 10.7554/eLife.57000

Genetic correlates of phenotypic heterogeneity in autism.

Autorzy: Varun Warrier, Xinhe Zhang, Patrick Reed, Alexandra Havdahl , Tyler M. Moore, Freddy Cliquet, Claire S. Leblond, Thomas Rolland, Anders Rosengren , EU-AIMS LEAP, iPSYCH-Autism Working Group, Spectrum 10K and APEX Consortia, David H. Rowitch, Matthew E. Hurles , Daniel H. Geschwind , Anders D. Børglum , Elise B. Robinson, Jakob Grove, Hilary C. Martin, Thomas Bourgeron and Simon Baron-Co
Opublikowane w: Nature Genetics, Numer 54, 2022, Strona(/y) 1293-1304, ISSN 1061-4036
Wydawca: Nature Publishing Group
DOI: 10.1038/s41588-022-01072-5

Associations between early language, motor abilities, and later autism traits in infants with typical and elevated likelihood of autism

Autorzy: Leyan Li, Greg Pasco, Jannath Begum Ali, Mark H. Johnson, Emily J. H. Jones, Tony Charman
Opublikowane w: Autism Research, Numer 16, 2023, Strona(/y) 2184-2197, ISSN 1939-3806
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/aur.3023

Severe white matter damage in SHANK3 deficiency: a human and translational study

Autorzy: Sarah Jesse, Hans‐Peter Müller, Michael Schoen, Harun Asoglu, Juergen Bockmann, Hans‐Juergen Huppertz, Volker Rasche, Albert C. Ludolph, Tobias M. Boeckers, Jan Kassubek
Opublikowane w: Annals of Clinical and Translational Neurology, Numer 7/1, 2019, Strona(/y) 46-58, ISSN 2328-9503
Wydawca: Annals of Clinical and Translational Neurology published by Wiley Periodicals, Inc on behalf of American Neurological Association
DOI: 10.1002/acn3.50959

Modulation of brain activation during executive functioning in autism with citalopram

Autorzy: Robert H. Wichers, James L. Findon, Auke Jelsma, Vincent Giampietro, Vladimira Stoencheva, Dene M. Robertson, Clodagh M. Murphy, Grainne McAlonan, Christine Ecker, Katya Rubia, Declan G. M. Murphy, Eileen M. Daly
Opublikowane w: Translational Psychiatry, Numer 9/1, 2019, ISSN 2158-3188
Wydawca: Nature Publishing Group
DOI: 10.1038/s41398-019-0641-0

Pharmacological and dietary-supplement treatments for autism spectrum disorder: a systematic review and network meta-analysis.

Autorzy: Siafis, S., Çıray, O., Wu, H., Schneider-Thoma, J., Bighelli, I., Krause, M., Rodolico, A., Ceraso, A., Deste, G., Huhn, M., Fraguas, D., San José Cáceres, A., Mavridis, D., Charman, T., Murphy, D. G., Parellada, M., Arango, C., & Leucht, S.
Opublikowane w: Molecular Autism, Numer 13, 2022, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-022-00488-4

Connectome-wide Mega-analysis Reveals Robust Patterns of Atypical Functional Connectivity in Autism.

Autorzy: Ilioska, I., Oldehinkel, M., Llera, A., Chopra, S., Looden, T., Chauvin, R., Van Rooij, D., Floris, D. L., Tillmann, J., Moessnang, C., Banaschewski, T., Holt, R. J., Loth, E., Charman, T., Murphy, D. G. M., Ecker, C., Mennes, M., Beckmann, C. F., Fornito, A., & Buitelaar, J. K.
Opublikowane w: Biological Psychiatry, Numer 94, 2023, Strona(/y) 29-39, ISSN 0006-3223
Wydawca: Elsevier BV
DOI: 10.1016/j.biopsych.2022.12.018

The Effect of Visual Perceptual Load on Auditory Awareness of Social vs. Non-social Stimuli in Individuals with Autism

Autorzy: Julian Tillmann, Jyrki Tuomainen, John Swettenham
Opublikowane w: Journal of Autism and Developmental Disorders, 2020, ISSN 0162-3257
Wydawca: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10803-020-04587-0

Deletion of the Autism-Associated Protein SHANK3 Abolishes Structural Synaptic Plasticity after Brain Trauma

Autorzy: Carolina Urrutia-Ruiz, Daniel Rombach, Silvia Cursano, Susanne Gerlach-Arbeiter, Michael Schoen,Juergen Bockmann, Maria Demestre andTobias M. Boeckers
Opublikowane w: International Journal of Molecular Sciences, Numer 23, 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23116081

The roles of sensory hyperreactivity and hyporeactivity in understanding infant fearfulness and emerging autistic traits

Autorzy: Nisha Narvekar, Virginia Carter Leno, Greg Pasco, Jannath Begum Ali, Mark H. Johnson, Tony Charman, Emily J. H. Jones, null null
Opublikowane w: Journal of Child Psychology and Psychiatry, Numer 65, 2024, Strona(/y) 1022-1036, ISSN 0021-9630
Wydawca: Blackwell Publishing Inc.
DOI: 10.1111/jcpp.13941

EEG signatures of cognitive and social development of preschool children–a systematic review

Autorzy: Bhavnani, Supriya; Lockwood Estrin, Georgia; Haartsen, Rianne; Jensen, Sarah K. G.; Gliga, Teodora; Patel, Vikram; Johnson, Mark H.
Opublikowane w: PLOS ONE, Numer 32, 2021, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0247223

Understanding Suicide Risk in Autistic Adults: Comparing the Interpersonal Theory of Suicide in Autistic and Non-autistic Samples

Autorzy: Mirabel K. Pelton, Hayley Crawford, Ashley E. Robertson, Jacqui Rodgers, Simon Baron-Cohen, Sarah Cassidy
Opublikowane w: Journal of Autism and Developmental Disorders, 2020, ISSN 0162-3257
Wydawca: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10803-020-04393-8

Quantitative genome-wide association study of six phenotypic subdomains identifies novel genome-wide significant variants in autism spectrum disorder

Autorzy: Afsheen Yousaf, Regina Waltes, Denise Haslinger, Sabine M. Klauck, Eftichia Duketis, Michael Sachse, Anette Voran, Monica Biscaldi, Martin Schulte-Rüther, Sven Cichon, Markus Nöthen, Jörg Ackermann, Ina Koch, Christine M. Freitag, Andreas G. Chiocchetti
Opublikowane w: Translational Psychiatry, Numer 10/1, 2020, ISSN 2158-3188
Wydawca: Nature Publishing Group
DOI: 10.1038/s41398-020-00906-2

Application of Airy beam light sheet microscopy to examine early neurodevelopmental structures in 3D hiPSC-derived human cortical spheroids

Autorzy: Dwaipayan Adhya, George Chennell, James A. Crowe, Eva P. Valencia-Alarcón, James Seyforth, Neveen A. Hosny, Marina V. Yasvoina, Robert Forster, Simon Baron-Cohen, Anthony C. Vernon & Deepak P. Srivastava
Opublikowane w: Molecular Autism, 2021, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-021-00413-1

Using multiple short epochs optimises the stability of infant EEG connectivity parameters

Autorzy: Rianne Haartsen, Bauke van der Velde, Emily J. H. Jones, Mark H. Johnson, Chantal Kemner
Opublikowane w: Scientific Reports, Numer 10/1, 2020, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-020-68981-5

A white paper on a neurodevelopmental framework for drug discovery in autism and other neurodevelopmental disorders.

Autorzy: C M Díaz-Caneja, M W State, R J Hagerman, S Jacquemont, O Marín, C Bagni, D Umbricht, E Simonoff, F de Andrés-Trelles, A Kaale, G Pandina, B Gómez-Mancilla, P P Wang, J Cusak, S Siafis, S Leucht, M Parellada, E Loth, T Charman, J K Buitelaar, D Murphy, C Arango
Opublikowane w: European Neuropsychopharmacology, Numer 48, 2021, Strona(/y) 49-88, ISSN 0924-977X
Wydawca: Elsevier BV
DOI: 10.1016/j.euroneuro.2021.02.020

The Synaptic Gene Study: Design and Methodology to Identify Neurocognitive Markers in Phelan-McDermid Syndrome and NRXN1 Deletions

Autorzy: Cooke, J., Molloy, C. J., Cáceres, A. S. J., Dinneen, T., Bourgeron, T., Murphy, D., Gallagher, L., & Loth, E.
Opublikowane w: 16, 2022, ISSN 1662-453X
Wydawca: Lausanne Frontiers Media S.A.
DOI: 10.3389/fnins.2022.806990

Facial expression recognition is linked to clinical and neurofunctional differences in autism.

Autorzy: Hannah Meyer‑Lindenberg, Carolin Moessnang, Bethany Oakley, Jumana Ahmad, Luke Mason, Emily J. H. Jones, Hannah L. Hayward, Jennifer Cooke, Daisy Crawley, Rosemary Holt, Julian Tillmann, Tony Charman, Simon Baron‑Cohen, Tobias Banaschewski, Christian Beckmann, Heike Tost, Andreas Meyer‑Lindenberg, Jan K. Buitelaar, Declan G. Murphy, Michael J. Brammer and Eva Loth
Opublikowane w: Molecular Autism, Numer 43, 2022, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-022-00520-7

Association of Race/Ethnicity and Social Disadvantage With Autism Prevalence in 7 Million School Children in England

Autorzy: Andres Roman-Urrestarazu, MD, PhD; Robin van Kessel, PhD; Carrie Allison, PhD; Fiona E. Matthews, PhD; Carol Brayne, MD; Simon Baron-Cohen, PhD
Opublikowane w: JAMA pediatrics, 2021, ISSN 2168-6203
Wydawca: American Medical Association
DOI: 10.1001/jamapediatrics.2021.0054

Development of sex- and genotype-specific behavioral phenotypes in a Shank3 mouse model for neurodevelopmental disorders

Autorzy: Bauer, H. F., Delling, J. P., Bockmann, J., Boeckers, T. M., & Schön, M.
Opublikowane w: Frontiers in Behavioral Neuroscience, 2023, ISSN 1662-5153
Wydawca: Frontiers Research Foundation
DOI: 10.3389/fnbeh.2022.1051175

Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets

Autorzy: Merel C. Postema, Daan van Rooij, Evdokia Anagnostou, Celso Arango, Guillaume Auzias, Marlene Behrmann, Geraldo Busatto Filho, Sara Calderoni, Rosa Calvo, Eileen Daly, Christine Deruelle, Adriana Di Martino, Ilan Dinstein, Fabio Luis S. Duran, Sarah Durston, Christine Ecker, Stefan Ehrlich, Damien Fair, Jennifer Fedor, Xin Feng, Jackie Fitzgerald, Dorothea L. Floris, Christine M. Freitag, Louise G
Opublikowane w: Nature Communications, Numer 10/1, 2019, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-13005-8

Immune activation during pregnancy exacerbates ASD-related alterations in Shank3-deficient mice

Autorzy: Atanasova, E., Arevalo, A., P., Graf, I., Zhang, R., Bockmann, J., Lutz, A-K., Boeckers, T. M
Opublikowane w: Molecular Autism, Numer 14, 2023, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-022-00532-3

SHANK3 deficiency leads to myelin defects in the central and peripheral nervous system.

Autorzy: Mariagiovanna Malara, Anne‑Kathrin Lutz, Berra Incearap, Helen Friedericke Bauer, Silvia Cursano, Katrin Volbracht, Joanna Janina Lerner, Rakshita Pandey, Jan Philipp Delling, Valentin Ioannidis, Andrea Pérez Arévalo, Jaime Eugenin von Bernhardi, Michael Schön, Jürgen Bockmann,· Leda Dimou, Tobias M. Boeckers
Opublikowane w: Cellular and Molecular Life Sciences, Numer 79, 2022, ISSN 1420-9071
Wydawca: Springer
DOI: 10.1007/s00018-022-04400-4

Dissecting the phenotypic heterogeneity in sensory features in autism spectrum disorder: a factor mixture modelling approach

Autorzy: J. Tillmann, M. Uljarevic, D. Crawley, G. Dumas, E. Loth, D. Murphy, J. Buitelaar, T. Charman
Opublikowane w: Molecular Autism, Numer 11/1, 2020, ISSN 2040-2392
Wydawca: BioMed Central
DOI: 10.1186/s13229-020-00367-w

Autism Is Associated With Interindividual Variations of Gray and White Matter Morphology.

Autorzy: Ting Mei, Natalie J. Forde, Dorothea L. Floris, Flavio Dell’Acqua, Richard Stones, Iva Ilioska, Sarah Durston, Carolin Moessnang, Tobias Banaschewski, Rosemary J. Holt, Simon Baron-Cohen, Annika Rausch, Eva Loth, Bethany Oakley, Tony Charman, Christine Ecker, Declan G.M. Murphy, the EU-AIMS LEAP group:Jan K. Buitelaar, Jumana Ahmad, Sara Ambrosino, Bonnie Auyeung, Tobias Banaschewski, Simon Baro
Opublikowane w: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging., Numer 8, 2022, Strona(/y) 1084-1093, ISSN 2451-9030
Wydawca: Elsevier
DOI: 10.1016/j.bpsc.2022.08.011

Autism with co-occurring epilepsy care pathway in Europe

Autorzy: Maria A. Mendez; Roberto Canitano; Bethany Oakley; Antonia San José-Cáceres; Michela Tinelli; Martin Knapp; James Cusack; Mara Parellada; Pierre Violland; Jan R. Derk Plas; Declan G. M. Murphy; Vinciane Quoidbach; Celso Arango
Opublikowane w: European Psychiatry, Vol 66 (2023), Numer 23, 2023, ISSN 1778-3585
Wydawca: Elsevier
DOI: 10.1192/j.eurpsy.2023.2426

A prospective study of associations between early fearfulness and perceptual sensitivity and later restricted and repetitive behaviours in infants with typical and elevated likelihood of autism

Autorzy: Narvekar, Nisha; Carter Leno, Virginia; Pasco, Greg; Johnson, Mark H.; Jones, Emily JH; Charman, Tony; The BASIS Team
Opublikowane w: Autism, Numer 52, 2022, ISSN 1362-3613
Wydawca: SAGE Publications
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Autistic Traits Mediate Reductions in Social Attention in Adults with Anorexia Nervosa

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