Rezultaty
Appointment of all SEAC members
Establishment of Board of Stakeholders
Programme for customised training courses
Standardised assays for the characterisation of HCPs by 1D/2D-PAGE followed by MS or MS/MS analysis
Metabolomic profiles of host responses to vaccination
Extension and refinement of dcRT-MLPA platform for extended gene expression profiling
Reduction and optimisation of small sample quantities for use in platforms
Standardised assays for the characterisation of candidate vaccine structure and integrity
Standardised human whole-blood Luminex assay for the characterisation of cytokine and chemokine responses induced by whole vaccines or vaccine antigens
Standardised human wholeblood Luminex assay for the characterisation of cytokine and chemokine responses induced by whole vaccines or vaccine antigens
Standardised assays for the characterisation of immune sera by calibration-free concentration analysisContact with five external projects and initiatives
Two rounds of customised training courses completed
Regulatory database for market access
Further development and optimisation of CyTOF technology platforms
Mathematical dynamic models that identify factors determining the magnitude and efficiency of the immune response upon vaccination
Development of SB platforms and analysis tools for immune cell differentiation, migration, cytokine profile and T-cell phenotype using SB analysis
Development of SB platforms and analysis tools for immune cell differentiation migration cytokine profile and Tcell phenotype using SB analysis
Neural network models for pattern recognition/classification of data in biobanksOptimisation of RNASeq platforms
Novel dcRT-MLPA assay for gene expression profiling in NHP models
Novel dcRTMLPA assay for gene expression profiling in NHP models
In vivo imaging for host pathogens interactions international workshopStandardised assays for the functional characterisation of vaccine candidates using monoclonal antibodies and/or ligand interactions
Regulatory database for therapeutic or prophylactic vaccine clinical trials
Optimisation of cytokine/chemokine multiplex platform analysis as innovative assays to evaluate innate immune responses in vitro directly using blood samples
Identification of regulatory bottlenecks affecting multinational cooperation in vaccine development
Report on COVID-19 services provided to TNA users.
Report on all services that will have been provided to TNA users for COVID19 projects
Communication policy and communication planReport on the future perspective of innovative telemetry and imaging methods
Impact reports
Workshop on mucosal vaccines and aerosol use in vaccine development
Workshop on aerosols in the development of mucosal vaccines and animal models
Provide and report on provision of access for structural analysisReport on the activities of the consultancy group and the feasibility of a self-sustaining Regulatory Advisory Expert Group
Report on the activities of the consultancy group and the feasibility of a selfsustaining Regulatory Advisory Expert Group
Detailed report on the technical, economical and regulatory aspects of an existing bench-scale processProtocol for the systematic organisation of a biobank and a corresponding database
Workshop on species-dependent aspects in animal models for vaccine evaluation
Workshop on speciesdependent aspects in animal models for vaccine evaluation
Business plan for a sustainable European vaccine R&D infrastructureReport on all measures used to promote the uptake of TRANSVAC2 services by industry
Detailed description of the infrastructure for the TRANSVAC2 web site
Terms of reference for, and composition of the consultancy expert panel
Workshop on harmonization of animal studies across different species
Reports on the publication of results in specialised scientifictechnical journals
Promotional activities at six meetingssymposia per year
Networking with other SB initiativesImplementation of an outreach campaign
Launch of TRANSVAC2 web site
Publikacje
Autorzy:
Jinpeng Su, Livia Brunner, Edanur Ates Oz, Julia Sacherl, Geraldine Frank, Helene Anne Kerth, Frank Thiele, Marian Wiegand, Carolin Mogler, Julio Cesar Aguilar, Percy A Knolle, Nicolas Collin, Anna D Kosinska, Ulrike Protzer
Opublikowane w:
Journal of Hepatology, 2023, ISSN 1600-0641
Wydawca:
Elsevier B.V.
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10.1016/j.jhep.2022.12.013
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Sergi López-Serrano, Lorena Cordoba, Mónica Pérez-Maillo, Patricia Pleguezuelos, Edmond J Remarque, Thomas Ebensen, Carlos A Guzmán, Dennis Christensen, Joaquim Segalés, Ayub Darji
Opublikowane w:
Vaccines, 2021, ISSN 2076-393X
Wydawca:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/vaccines9070751
Autorzy:
Pauline Maisonnasse, Jérémie Guedj, Vanessa Contreras, Sylvie Behillil, Caroline Solas, Romain Marlin, Thibaut Naninck, Andres Pizzorno, Julien Lemaitre, Antonio Gonçalves, Nidhal Kahlaoui, Olivier Terrier, Raphael Ho Tsong Fang, Vincent Enouf, Nathalie Dereuddre-Bosquet, Angela Brisebarre, Franck Touret, Catherine Chapon, Bruno Hoen, Bruno Lina, Manuel Rosa Calatrava, Sylvie van der Werf, Xavi
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Nature, 2020, ISSN 1476-4687
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Nature Publishing Group
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10.1038/s41586-020-2558-4
Autorzy:
Brima M. Younis,1 Mohamed Osman,2 Eltahir A.G. Khalil,1 Francesco Santoro,3 Simone Furini,3 Rebecca Wiggins,2 Ada Keding,4 Monica Carraro,3 Anas E.A. Musa,1 Mujahid A.A. Abdarahaman,1 Laura Mandefield,4 Martin Bland,4 Toni Aebischer,5 Rhian Gabe,6 Alison M. Layton,2 Charles J.N. Lacey,2,7 Paul M. Kaye,2,7,∗ and Ahmed M. Musa1,7,∗∗
Opublikowane w:
Molecular Therapy, 2019, ISSN 1525-0016
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Nature Publishing Group
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10.1016/j.ymthe.2021.03.020
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Pierre Rosenbaum, Nicolas Tchitchek, Candie Joly, André Rodriguez Pozo, Lev Stimmer, Sébastien Langlois, Hakim Hocini, Leslie Gosse, David Pejoski, Antonio Cosma, Anne-Sophie Beignon, Nathalie Dereuddre-Bosquet, Yves Levy, Roger Le Grand, Frédéric Martinon
Opublikowane w:
Frontiers in Immunology, 2021, ISSN 1664-3224
Wydawca:
Frontiers
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10.3389/fimmu.2021.645210
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Bárbara Fernandes, Marcos Sousa, Rute Castro, Anja Schäfer, Julia Hauser, Kai Schulze, Mario Amacker, Marco Tamborrini, Gerd Pluschke, Paula M Alves, Sylvain Fleury, António Roldão
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Frontiers in Bioengineering and Biotechnology, 2022, ISSN 2296-4185
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Frontiers Media S.A.
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10.3389/fbioe.2022.879078
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Coraline Chéneau, Karsten Eichholz, Tuan Hiep Tran, Thi Thu Phuong Tran, Océane Paris, Corinne Henriquet, Jeffrey J Bajramovic, Martine Pugniere, Eric J Kremer
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Frontiers Immunology, 2021, ISSN 1664-3224
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Frontiers
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10.3389/fimmu.2021.685218
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Elena Pettini, Gabiria Pastore, Fabio Fiorino, Donata Medaglini, Annalisa Ciabattini
Opublikowane w:
Vaccines, 2021, ISSN 2076-393X
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Multidisciplinary Digital Publishing Institute (MDPI)
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10.3390/vaccines9030289
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Jean-Louis Palgen, Nicolas Tchitchek, André Rodriguez-Pozo, Quentin Jouhault, Hadjer Abdelhouahab, Nathalie Dereuddre-Bosquet, Vanessa Contreras, Frédéric Martinon, Antonio Cosma, Yves Lévy, Roger Le Grand, and Anne-Sophie Beignon
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NPJ Vaccines, 2020, ISSN 2059-0105
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Springer Nature
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10.1038/s41541-020-0175-8
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Christian Lanfermann, Sebastian Wintgens, Thomas Ebensen, Martin Kohn, Robert Laudeley, Kai Schulze, Claudia Rheinheimer, Johannes H Hegemann, Carlos Alberto Guzmán, Andreas Klos
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Vaccines, 2021, ISSN 2076-393X
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Multidisciplinary Digital Publishing Institute (MDPI)
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10.3390/vaccines9060609
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Veterinary Research, 2020, ISSN 1297-9716
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Public Library of Science
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Animals, 2021, ISSN 2076-2615
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10.3390/ani11010204
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Nature Reviews Drug Discovery, 2022, ISSN 1474-1776
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Cell, 2021, ISSN 0092-8674
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Pharmaceutics, 2021, ISSN 1999-4923
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Pharmaceutics, 2020, ISSN 1999-4923
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Cell Reports Medicine, 3(2):100528. Cell Press, Numer 35, 2022, ISSN 2666-3791
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Bárbara Fernandes , Rute Castro , Farien Bhoelan , Denzel Bemelman , Ricardo A Gomes , Júlia Costa , Patrícia Gomes-Alves , Toon Stegmann , Mario Amacker 5, Paula M Alves , Sylvain Fleury , António Roldão
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Pharmaceutics, 2022, ISSN 1999-4923
Wydawca:
Multidisciplinary Digital Publishing Institute (MDPI)
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Nerea Zabaleta,1,2,3,4 Wenlong Dai,1,2,3,4 Urja Bhatt,1,2,3,4 Cécile Hérate,5 Pauline Maisonnasse,5 Jessica A. Chichester,6 Julio Sanmiguel,1,2,3,4 Reynette Estelien,1,2,3,4 Kristofer T. Michalson,6 Cheikh Diop,1,2,3,4 Dawid Maciorowski,1,2,3,4 Nathalie Dereuddre-Bosquet,5 Mariangela Cavarelli,5 Anne-Sophie Gallouët,5 Thibaut Naninck,5 Nidhal Kahlaoui,5 Julien Lemaitre,5 Wenbin Qi,7 Elissa Huds
Opublikowane w:
Cell Host & Microbe, 2021, ISSN 1931-3128
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Cell Press
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10.1016/j.chom.2021.08.002
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Karin Dijkman
Nacho Aguilo
Charelle Boot
Sam O. Hofman
Claudia C. Sombroek
Richard A.W. Vervenne
Clemens H.M. Kocken
Dessislava Marinova
Jelle Thole
Esteban Rodríguez
Michel P.M. Vierboom
Krista G. Haanstra
Eugenia Puentes
Carlos Martin
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Cell Rep Med., 2021, ISSN 2666-3791
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Cell Press
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Frontiers in Bioengineering and Biotechnology, 2023, ISSN 2296-4185
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Vaccine X, 2023, ISSN 2590-1362
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Elsevier Ltd.
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Vaccines, 2022, ISSN 2076-393X
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Multidisciplinary Digital Publishing Institute (MDPI)
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Molecular Systems Biology, Numer 15/11, 2019, ISSN 1744-4292
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Simone Lucchesi, Emanuele Nolfi, Elena Pettini, Gabiria Pastore, Fabio Fiorino, Gianni Pozzi, Donata Medaglini, Annalisa Ciabattini
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Cytometry Part A, Numer 97/3, 2020, Strona(/y) 259-267, ISSN 1552-4922
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Gabiria Pastore, Monica Carraro, Elena Pettini, Emanuele Nolfi, Donata Medaglini, Annalisa Ciabattini
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Frontiers in Immunology, Numer 10, 2019, ISSN 1664-3224
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PLOS ONE, Numer 14/3, 2019, Strona(/y) e0212431, ISSN 1932-6203
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Scientific Reports, 2021, ISSN 2045-2322
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Molecular Immunology, 2021, ISSN 0161-5890
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Pergamon Press
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10.1016/j.molimm.2021.04.010
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PLoS ONE, Numer 35, 2019, ISSN 1932-6203
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Public Library of Science
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iScience, 2022, ISSN 2589-0042
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Cell Press
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10.1016/j.isci.2022.104101
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Mikelson, Jan; Khammash, Mustafa Hani; id_orcid0000-0002-4855-9220
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PLoS Computational Biology, 16 (10), Numer 8, 2020, ISSN 1553-734X
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Seminars in Immunopathology, 2020, ISSN 1863-2297
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Springer Verlag
DOI:
10.1007/s00281-020-00821-0
Autorzy:
Brendan Farrell, Nawsad Alam, Melissa N. Hart, Abhishek Jamwal, Robert J. Ragotte, Hannah Walters-Morgan, Simon J. Draper, Ellen Knuepfer, Matthew K. Higgins
Opublikowane w:
bioRxiv, 2023, ISSN 2692-8205
Wydawca:
Cold Spring Harbor Laboratory
DOI:
10.1101/2023.01.30.526221
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