Rezultaty
These will be prepared following each Annual Meeting, they will include the main topics of discussion during these events, specifically focusing on major progress milestones and results that can have specific interest to major stakeholders and end-users.
Project HandbookThe Project Handbook is to be taken as a collated support document covering all deadlines and procedures related with decision-making structure, financial reporting, corrective actions, and all aspects involved with managing the project. Partners will be provided a copy and it will be periodically reviewed and updated if necessary
Report on Pilot Studies with Quantum Dot TechnologyResults of pilot studies detecting multi transcript signatures by quantum dot technology.
Report on results from multi transcript signature detection via electronic sensorsResults of alternative approaches to detect multi transcript signatures using electro sensors. Evaluation of results from studies in collaboration with POC-ID.
All Approvals PackageCopies of all approvals from ethics committees and national or regional ethics boards/bodies/administrations to be submitted to the European commission. These include approvals for transfer of biological samples and data between parties and any third party. Ethics approvals must cover approval of local institutions where samples are collected as well as overall national approval
Impact Model of Diagnostic on Antimicrobial resistanceConceptual model of impact of diagnostic on antimicrobial resistance
Report on Rna-Seq and Microarray StudiesSummary report on RNAseq and microarray studies for Discovery group
Mid-Term Recruitment ReportOverview of recruitment by study site including numbers, recruiting problems and any measures made to compensate if recruitment delays occurred. (Per study)
2nd Annual Meeting ReportThese will be prepared following each Annual Meeting, they will include the main topics of discussion during these events, specifically focusing on major progress milestones and results that can have specific interest to major stakeholders and end-users.
Final Ethics ReviewFinal report from Ethics Review Board on study conduction
Consent and Child Assent FormsCopies of consent forms and child assent forms (in each partner language) submitted to confirm compliance with Article 29 workgroup paper WP131 on processing personal data in health records, and confirming that the consent forms cover the right to withdraw from studies including withdrawal of samples and data.
Ethics Review ReportIndependent ethics review board submits second report on ethical issues and conduct of the study
4th Final Meeting ReportThese will be prepared following each Annual Meeting, they will include the main topics of discussion during these events, specifically focusing on major progress milestones and results that can have specific interest to major stakeholders and end-users.
Tool-server PlatformsTool-server platforms: allowing computational tools and workflows to be deployed on the integrated data including custom ones developed by project
PERFORM Dissemination & Communnication StrategyWill outline the approach PERFORM will take towards the communication of its activities and results to relevant audiences, end-users, policy-makers and stakeholders. The document will include the strategic approach the consortium has selected to maximize the effectiveness and impact of its expected outcomes. It will also include all chosen communication channels and platforms to be developed and used across the duration of the project.
Transcriptomic and proteomic signatures of bacterial and viral infectionsReport on transcriptomic and proteomic signatures that distinguish bacterial and viral infections in the discovery cohort
Provider, Parent and Costing StudiesReports on provider, parent and costing studies
Performance of RNA and protein expression modelsReport on performance of RNA and protein expression models in validation of prospective cohorts from emergency departments PICU and inpatient cohorts
Ethics Board Report (Preliminary)Initial report of independent ethics review board on the documents for patient consent and the procedures for patient data and sample collection and overall ethical procedures submitted
Report on Feasibility and Implementation of Novel DiagnosticsReport on feasibility and implementation assessment of novel diagnostic
Recruitment Completion ReviewCompletion of recruitment and patient assignment for all prospective studies (BIVABI, BIVA- ED, BIVA-PIC, BIVA-INF and MOFICHE); samples and patient data sent for analysis. Includes report on updating the status of study registry.
report on protein biomarkersReport on the performance of individual biomarker proteins
selection of platformreport on the selection of platform to develop prototype diagnostic
Transcriptomic Markers for bacterial and viral infectionsReport studies of transcriptomic markers to differentiate febrile patients with bacterial and viral infection in the validation cohorts
Models of novel proteomic and genomic markersDelivery of a range of options based on models on how a novel proteomic or genomic marker would influence patient care flows
report on molecular diagnosticsreport on the outcome of molecular bacterial and viral diagnostic studies
Operational DatabaseDelivery of operational database, housing clinical and laboratory data
Final Meeting ReportThese will be prepared following each Annual Meeting, they will include the main topics of discussion during these events, specifically focusing on major progress milestones and results that can have specific interest to major stakeholders and end-users.
New Management Algorithm ModelFinal delivery of proposed new management algorithm including the use of genomic proteomic or clinical biomarkers identified during our programme with evaluation of cost benefit patient safety and overall healthcare benefit which would be obtained if the model were Implemented
1st Annual Meeting ReportThese will be prepared following each Annual Meeting, they will include the main topics of discussion during these events, specifically focusing on major progress milestones and results that can have specific interest to major stakeholders and end-users.
Mass Spectrometry Proteomic AnalysisDelivery of Mass spectrometry proteomic analysis on discovery cohort
Models of Novel Diagnostic TestsDelivery of models describing the performance of the novel diagnostic tests
Clinical Recruitment & Data Collection DocumentsClinical recruitment and data collection documents for all prospective studies (BIVABI, BIVA- ED, BIVA-PIC, BIVA-INF and MOFICHE) finalised and agreed by PERFORM consortium. These documents to include the first study subject approvals package – with the final version of study protocol, registration number in an approved registry, ethics approval for main study site.
The project will develop and use a dedicated website to improve engagement with its end-users and stakeholders. It is the aim of the project to keep its website up to date with the latest activities and outcomes, so as to maximize it's impact with regards to the main interested parties.
Publikacje
Autorzy:
"""U. Effua, F. Secka, I. Sarr, M.A. Zaman, K. Bojang, A. Roca, O. N and on Behalf Of The Perform
Consoritum"""
Opublikowane w:
ESPID 2020 Abstract Book, 2020
Wydawca:
ESPID 2020 Abstract Book
Autorzy:
F. Van Der Velden, P. Agyeman, U. Von Both,, E. Carrol, C. Fink, J. Herberg, T. Kuijpers, F. Martinón-Torres, H. Moll, M. Pokorn, A. Pollard, L. Schlapbach, M. Tsolia, S. Yeung, D. Zavadska, W. Zenz, M. Levin, M. Van Der Flier, M. Emonts, On Behalf Or Perform Consortium
Opublikowane w:
ESPID 2021 Abstract book, Numer May 2021, 2021
Wydawca:
ESPID
Autorzy:
"""U. Effua, M. Voice, F. Secka, I. Sarr, M.A. Zaman, K. Bojang, A. Roca, N. ‘On Behalf Of The
Perform Consortium"""
Opublikowane w:
ESPID 2020 Abstract Book, 2020
Wydawca:
ESPID 2020 Abstract Book
Autorzy:
A. Khanijau, L.Kolberg, F. Van Der Velden, J. Herberg, T. Kuijpers, F. Martinón-Torres, H. Moll, M. Pokorn, A. Pollard, L. Schlapbach, M. Tsolia, S. Yeung, D. Zavadska, W. Zenz, M. Van Der Flier, M. Levin, E. Carrol, M. Emonts, U. Von Both, On Behalf Of Perform Consortium
Opublikowane w:
ESPID2021, Numer May 2021, 2021
Wydawca:
ESPID
Autorzy:
I. Rivero-Calle, J. Pardo-Seco, M. Cebey-López, F. Martinón-Torres, P. Consortium
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ESPID 2020 Abstract Book, 2020
Wydawca:
ESPID 2020 Abstract Book
Autorzy:
Dorine Borensztajn, Nienke Hagedoorn, Ulrich von Both, Enitan D. Carrol, Manuel Dewez, Marieke Emonts, Michiel van der Flier, Ronald de Groot, Jethro Herberg, Benno Kohlmaier, Emma Lim, Ian Maconochie, Federico Martinon-Torres, Ruud Nijman, Marko Pokorn, Franc Strle, Maria Tsolia, Clementien Vermont, Shunmay Yeung, Dace Zavadska, Werner Zenz, Michael Levin, Henriëtte A Moll
Opublikowane w:
European Society for Emergency Medicine abstract book, 2019
Wydawca:
EUSEM
Autorzy:
Nienke Hagedoorn, Dorine Borensztajn, Ian Maconochie, Ruud Nijman, Federico Martinon-Torres, Jethro Herberg, Enitan Carrol, Emma Lim, Maria Tsolia, Marieke Emonts, Ronald de Groot, Michiel van der Flier, Werner Zenz, Benno Kohlmaier, Franc Strle, Marko Pokorn, Dace Zavadska, Ulrich von Both, Clementien Vermont, Shunmay Yeung, Michael Levin,
Henriëtte Moll
Opublikowane w:
European Society for Emergency Medicine abstract book, 2019
Wydawca:
EUSEM
Autorzy:
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Opublikowane w:
Retrieving data. Wait a few seconds and try to cut or copy again., 2020
Wydawca:
Retrieving data. Wait a few seconds and try to cut or copy again.
Autorzy:
P. Shah, M. Voice, C. Fink, J.Herberg, L. Calvo-Bado, On Behalf Or Perform Consortium
Opublikowane w:
ESPID 2021 Abstract book, 2021
Wydawca:
ESPID 2021 Abstract book
Autorzy:
J. Dewez, S. Yeung, O.B.O. Perform/eaprasnet Study Group
Opublikowane w:
ESPID 2020 Abstract Book, 2020
Wydawca:
ESPID2020
Autorzy:
Lanette Kempers, Evelien G. G. Sprenkeler, Abraham C. I. van Steen, Jaap D. van Buul, Taco W. Kuijpers
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Frontiers in Immunology, Numer 12, 2021, Strona(/y) 12:2062, ISSN 1664-3224
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frontiers media
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Frontiers in Cellular and Infection Microbiology, Numer 9, 2020, Strona(/y) 459, ISSN 2235-2988
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PLOS ONE, Numer 16/1, 2021, Strona(/y) e0244810, ISSN 1932-6203
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Public Library of Science
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Journal of Innate Immunity, Numer 13/1, 2021, Strona(/y) 3-25, ISSN 1662-811X
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Blood, Numer 135/24, 2020, Strona(/y) 2171-2181, ISSN 0006-4971
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Opublikowane w:
Archives of Disease in Childhood, Numer June 2021, 2021, Strona(/y) archdischild-2020-320992, ISSN 0003-9888
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BMJ Publishing Group
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Nienke N. Hagedoorn, Dorine M. Borensztajn, Ruud Nijman, Anda Balode, Ulrich von Both, Enitan D. Carrol, Irini Eleftheriou, Marieke Emonts, Michiel van der Flier, Ronald de Groot, Jethro Herberg, Benno Kohlmaier, Emma Lim, Ian Maconochie, Federico Martinon-Torres, Daan Nieboer, Marko Pokorn, Franc Strle, Maria Tsolia, Shunmay Yeung, Dace Zavadska, Werner Zenz, Clementien Vermont, Michael Levin, He
Opublikowane w:
PLOS Medicine, Numer 17/8, 2020, Strona(/y) e1003208, ISSN 1549-1676
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Public Library of Science
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Journal of Antimicrobial Chemotherapy, Numer 76/5, 2021, Strona(/y) 1349-1357, ISSN 0305-7453
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Archives of Disease in Childhood, Numer 105/8, 2020, Strona(/y) 765-771, ISSN 0003-9888
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Heather Jackson, Stephanie Menikou, Shea Hamilton, Andrew McArdle, Chisato Shimizu, Rachel Galassini, Honglei Huang, Jihoon Kim, Adriana Tremoulet, Adam Thorne, Roman Fischer, Marien de Jonge, Taco Kuijpers, Victoria Wright, Jane Burns, Climent Casals-Pascual, Jethro Herberg, Mike Levin, Myrsini Kaforou
Opublikowane w:
International Journal of Molecular Sciences, Numer 22/11, 2021, Strona(/y) 5655, ISSN 1422-0067
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Multidisciplinary Digital Publishing Institute (MDPI)
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Bioinformatics, Numer 35/24, 2019, Strona(/y) 5182-5190, ISSN 1367-4803
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Oxford University Press
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Opublikowane w:
BMC Medicine, Numer 17/1, 2019, ISSN 1741-7015
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BioMed Central
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Anouk Suppers, Alain van Gool, Hans Wessels
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Proteomes, Numer 6/2, 2018, Strona(/y) 20, ISSN 2227-7382
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BMJ Open, Numer 10/5, 2020, Strona(/y) e035343, ISSN 2044-6055
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Esther Willems, Wynand Alkema, Jenneke Keizer-Garritsen, Anouk Suppers, Michiel van der Flier, Ria H.L.A. Philipsen, Lambert P. van den Heuvel, Elena Volokhina, Renate G. van der Molen, Jethro A. Herberg, Michael Levin, Victoria J. Wright, Inge M.L. Ahout, Gerben Ferwerda, Marieke Emonts, Navin P. Boeddha, Irene Rivero-Calle, Federico Martinon Torres, Hans J.C.T. Wessels, Ronald de Groot, Alain J.
Opublikowane w:
EBioMedicine, Numer 45, 2019, Strona(/y) 303-313, ISSN 2352-3964
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Elizabeth Whittaker, Alasdair Bamford, Julia Kenny, Myrsini Kaforou, Christine E. Jones, Priyen Shah, Padmanabhan Ramnarayan, Alain Fraisse, Owen Miller, Patrick Davies, Filip Kucera, Joe Brierley, Marilyn McDougall, Michael Carter, Adriana Tremoulet, Chisato Shimizu, Jethro Herberg, Jane C. Burns, Hermione Lyall, Michael Levin
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Critical Care, Numer 23/1, 2019, ISSN 1364-8535
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Annemarie Geer, Judith Zandstra, Michael W. T. Tanck, Erfan Nur, Gerard Mierlo, Ilse Jongerius, Robin Bruggen, Sacha S. Zeerleder, Taco W. Kuijpers
Opublikowane w:
British Journal of Haematology, Numer 193/5, 2021, Strona(/y) 1008-1012, ISSN 0007-1048
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Heidi Hopkins, Quique Bassat, Clare IR Chandler, John A Crump, Nicholas A Feasey, Rashida A Ferrand, Katharina Kranzer, David G Lalloo, Mayfong Mayxay, Paul N Newton, David Mabey
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Opublikowane w:
The American Journal of Human Genetics, Numer 108/8, 2021, Strona(/y) 1367-1384, ISSN 0002-9297
Wydawca:
University of Chicago Press
DOI:
10.1016/j.ajhg.2021.06.002
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