Reaching the effects of gastric bypass on diabetes and obesity without surgery

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R–dependent manner

Autores: Jepsen SL, Albrechtsen NJW, Windeløv JA, Galsgaard KD, Hunt JE, Farb TB, Kissow H, Pedersen J, Deacon CF, Martin RE, Holst JJ
Publicado en: JCI Insight, 2021, ISSN 2379-3708
Editor: JCI insight
DOI: 10.1172/jci.insight.143228

Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

Autores: Sarina Gadgaard; Wijnand J.C. van der Velden; Wijnand J.C. van der Velden; Sine P. Schiellerup; Jenna Hunt; Maria Buur Nordskov Gabe; Johanne Agerlin Windeløv; Geke Aline Boer; Hannelouise Kissow; Cathrine Ørskov; Jens J. Holst; Bolette Hartmann; Mette M. Rosenkilde
Publicado en: British Journal of Pharmacology, Edición 1, 2021, ISSN 0007-1188
Editor: Wiley-Blackwell
DOI: 10.1111/bph.15766

L-Cell Expression of Melanocortin-4-Receptor Is Marginal in Most of the Small Intestine in Mice and Humans and Direct Stimulation of Small Intestinal Melanocortin-4-Receptors in Mice and Rats Does Not Affect GLP-1 Secretion.

Autores: Kuhre RE, Modvig IM, Jepsen SL, Kizilkaya HS, Bæch-Laursen C, Smith CA, Reimann F, Gribble FM, Rosenkilde MM, Holst JJ.
Publicado en: Front Endocrinol (Lausanne), 2021, ISSN 1664-2392
Editor: Frontiers of Endocrinology
DOI: 10.3389/fendo.2021.690387

Follistatin secretion is enhanced by protein, but not glucose or fat ingestion, in obese persons independently of previous gastric bypass surgery

Autores: Bojsen-Møller KN, Svane MS, Jensen CZ, Kjeldsen SAS, Holst JJ, Wewer Albrechtsen NJ, Madsbad S.
Publicado en: Am J Physiol Gastrointest Liver Physiol, 2021, ISSN 0193-1857
Editor: American Physiological Society
DOI: 10.1152/ajpgi.00396.2020

Effects of Manipulating Circulating Bile Acid Concentrations on Postprandial GLP-1 Secretion and Glucose Metabolism After Roux-en-Y Gastric Bypass.

Autores: Isabella Jonsson; Kirstine N. Bojsen-Møller; Kirstine N. Bojsen-Møller; Viggo B. Kristiansen; Simon Veedfald; Nicolai J. Wewer Albrechtsen; Nicolai J. Wewer Albrechtsen; Nicolai J. Wewer Albrechtsen; Trine R. Clausen; Rune E. Kuhre; Rune E. Kuhre; Jens F. Rehfeld; Jens J. Holst; Sten Madsbad; Sten Madsbad; Maria S. Svane; Maria S. Svane; Maria S. Svane
Publicado en: Frontiers in Endocrinology, Vol 12 (2021), Edición 1, 2021, ISSN 1664-2392
Editor: Frontiers in Endocrinology
DOI: 10.3389/fendo.2021.681116

Postprandial secretion of follistatin after gastric bypass surgery and sleeve gastrectomy

Autores: Richter MM, Svane MS, Kristiansen VB, Holst JJ, Madsbad S, Bojsen-Møller KN.
Publicado en: Peptides, 2019, ISSN 0196-9781
Editor: Elsevier BV
DOI: 10.1016/j.peptides.2023.170978

Responses of gut and pancreatic hormones, bile acids, and fibroblast growth factor-21 differ to glucose, protein, and fat ingestion after gastric bypass surgery

Autores: Christian Zinck Jensen; Kirstine N. Bojsen-Møller; Maria S. Svane; Line Marie Broksø Holst; Kjeld Hermansen; Bolette Hartmann; Nicolai J. Wewer Albrechtsen; Rune E. Kuhre; Viggo B. Kristiansen; Jens F. Rehfeld; Trine R. Clausen; Jens J. Holst; Sten Madsbad
Publicado en: Nutrient sensing, Nutrition and Metabolism, Edición 1, 2020, ISSN 1548-9213
Editor: American Physiological Society
DOI: 10.1152/ajpgi.00265.2019

CCK-1 and CCK-2 receptor agonism do not stimulate GLP-1 and neurotensin secretion in the isolated perfused rat small intestine or GLP-1 and PYY secretion in the rat colon.

Autores: Ida M. Modvig; C. Christiansen; Jens F. Rehfeld; Jens J. Holst; Simon Veedfald
Publicado en: Physiological Reports, Edición 1, 2020, ISSN 2051-817X
Editor: Wiley
DOI: 10.14814/phy2.14352

Intestinal sensing and handling of dietary lipids in gastric bypass- operated patients and matched controls

Autores: Martinussen C, Dirksen C, Bojsen-Møller KN, Svane MS, Carlsson ER, Hartmann B, Clausen TR, Veedfald S, Kristiansen VB, Rehfeld JF, Hansen HS, Holst JJ, Madsbad S.
Publicado en: Am J Clin Nutr, 2020, ISSN 1938-3207
Editor: American Journal of Clinical Nutrition
DOI: 10.1093/ajcn/nqz272

l-valine is a powerful stimulator of GLP-1 secretion in rodents and stimulates secretion through ATP-sensitive potassium channels and voltage-gated calcium channels

Autores: Ida Marie Modvig, Mark M. Smits, Katrine Douglas Galsgaard, Anna Pii Hjrne, Anna Katarzyna Drzazga, Mette Marie Rosenkilde, Jens Juul Holst
Publicado en: Nutrition & Diabetes, Edición 14, 2024, ISSN 2044-4052
Editor: Nutrition and Diabetes
DOI: 10.1038/s41387-024-00303-4

Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty

Autores: Svane MS, Øhrstrøm CC, Plamboeck A, Jørgensen NB, Bojsen-Møller KN, Dirksen C, Martinussen C, Vilsbøll T, Hartmann B, Deacon CF, Kristiansen VB, Knop FK, Svendsen LB, Madsbad S, Holst JJ, Veedfald S.
Publicado en: Neurogastroenterol Motility, 2022, ISSN 2093-0879
Editor: Korean Society of Neurogastroenterology and Motility
DOI: 10.1111/nmo.14210

Incretin Hormones and Type 2 Diabetes – Mechanistic Insights and Therapeutic Approaches

Autores: Geke Aline Boer; Jens J. Holst
Publicado en: https://www.preprints.org/manuscript/202011.0684/v1, Edición 1, 2020, ISSN 2079-7737
Editor: MDPI
DOI: 10.3390/biology9120473

Effect of ghrelin on glucose tolerance, gut hormones, appetite, and food intake after sleeve gastrectomy

Autores: Nora Hedbck, Marie-Louise Dichman, Morten Hinds, Carsten Dirksen, Nils Brun Jrgensen, Kirstine Nyvold Bojsen-Mller, Viggo B. Kristiansen, Jens F. Rehfeld, Bolette Hartmann, Jens Juul Holst, Maria Saur Svane, Sten Madsbad
Publicado en: American Journal of Physiology-Endocrinology and Metabolism, Edición 327, 2024, Página(s) E396-E410, ISSN 0193-1849
Editor: American Physiological Society
DOI: 10.1152/ajpendo.00177.2024

The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

Autores: Hindsø M, Hedbäck N, Svane MS, Møller A, Martinussen C, Jørgensen NB, Dirksen C, Gasbjerg LS, Kristiansen VB, Hartmann B, Rosenkilde MM, Holst JJ, Madsbad S, Bojsen-Møller KN
Publicado en: Diabetes, 2023, ISSN 0012-1797
Editor: American Diabetes Association
DOI: 10.2337/db22-0568

Four weeks treatment with the GLP-1 receptor analogue liraglutide lowers liver fat and concomitantly circulating glucagon in individuals with overweight.

Autores: Svane MS, Johannesen HH, Hansen AE, Martinussen C, Bojsen-Møller KN, Hansen ML, Deacon CF, Keller SH, Klausen TL, Loft A, Kjaer A, Löfgren J, Madsbad S, Holst JJ, Wewer Albrechtsen NJ.
Publicado en: Int J Obes, 2022, ISSN 0307-0565
Editor: Nature Publishing Group
DOI: 10.1038/s41366-022-01207-y

Using a Reporter Mouse to Map Known and Novel Sites of GLP-1 Receptor Expression in Peripheral Tissues of Male Mice.

Autores: Daniel B. Andersen; Kaare V. Grunddal; Jens Pedersen; Rune E. Kuhre; Mari L. Lund; Jens J. Holst; Cathrine Ørskov
Publicado en: Endocrinology, Edición 1, 2021, ISSN 0013-7227
Editor: The Endocrine Society
DOI: 10.1210/endocr/bqaa246

Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays

Autores: Geke Aline Boer; Bolette Hartmann; Jens J. Holst
Publicado en: Peptides, Edición 1, 2021, ISSN 0196-9781
Editor: Elsevier BV
DOI: 10.1016/j.peptides.2020.170457

Secretin release after Roux-en-Y gastric bypass reveals a population of glucose-sensitive S cells in distal small intestine.

Autores: Ida M. Modvig; Daniel B. Andersen; Kaare V. Grunddal; Rune E. Kuhre; Christoffer Martinussen; C. Christiansen; Cathrine Ørskov; Pierre Larraufie; Richard G. Kay; Frank Reimann; Fiona M. Gribble; Bolette Hartmann; Kirstine N. Bojsen-Møller; Sten Madsbad; Nicolai J. Wewer Albrechtsen; Jens J. Holst
Publicado en: International Journal of Obesity, Edición 14, 2020, Página(s) 1859-1871, ISSN 0307-0565
Editor: Nature Publishing Group
DOI: 10.17863/cam.56634

Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine.

Autores: Valeria Booz; C. Christiansen; Rune E. Kuhre; Monika Yosifova Saltiel; Giovanna Sociali; Nicola Schaltenberg; Alexander W. Fischer; Joerg Heeren; Elena Zocchi; Jens J. Holst; Santina Bruzzone
Publicado en: Diabetes & Metabolism, Edición 2, 2018, ISSN 2233-6079
Editor: Korean Diabetes Association
DOI: 10.1002/dmrr.3102

The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery.

Autores: Martinussen C, Veedfald S, Dirksen C, Bojsen-Møller KN, Svane MS, Wewer Albrechtsen NJ, van Hall G, Kristiansen VB, Fenger M, Holst JJ, Madsbad S.
Publicado en: Am J Physiol Endocrinol Metab, 2020, ISSN 1548-9213
Editor: American Physiological Society
DOI: 10.1152/ajpendo.00023.2020

Glucose-dependent insulinotropic polypeptide receptor antagonist treatment causes a reduction in weight gain in ovariectomised high fat diet-fed mice.

Autores: Boer GA, Hunt JE, Gabe MBN, Windeløv JA, Sparre-Ulrich AH, Hartmann B, Holst JJ, Rosenkilde MM.
Publicado en: Br J Pharmacol., 2022, ISSN 0007-1188
Editor: Wiley-Blackwell
DOI: 10.1111/bph.15894

Effect of the Natural Sweetener Xylitol on Gut Hormone Secretion and Gastric Emptying in Humans: A Pilot Dose-Ranging Study

Autores: Meyer-Gerspach AC, Drewe J, Verbeure W, Roux CWL, Dellatorre-Teixeira L, Rehfeld JF, Holst JJ, Hartmann B, Tack J, Peterli R, Beglinger C, Wölnerhanssen BK.
Publicado en: Nutrients, 2021, ISSN 2072-6643
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu13010174

Amino acids differ in their capacity to stimulate GLP-1 release from the perfused rat small intestine and stimulate secretion by different sensing mechanisms.

Autores: Modvig IM, Kuhre RE, Jepsen SL, Xu SFS, Engelstoft MS, Egerod KL, Schwartz TW, Ørskov C, Rosenkilde MM, Holst JJ
Publicado en: Am J Physiol Endocrinol Metab, 2021, ISSN 1548-9213
Editor: American Physiological Society
DOI: 10.1152/ajpendo.00026.2021

Hepatic Bile Acid Reuptake in the Rat Depends on Bile Acid Conjugation but Not on Agonistic Properties towards FXR and TGR5.

Autores: Samuel A.J. Trammell; Jens S. Svenningsen; Jens J. Holst; Matthew P. Gillum; Rune E. Kuhre
Publicado en: Molecules, Vol 25, Iss 2371, p 2371 (2020), Edición 1, 2020, ISSN 1420-3049
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules25102371

Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance.

Autores: Hindsø M, Bojsen-Møller KN, Kristiansen VB, Holst JJ, van Hall G, Madsbad S.
Publicado en: Int J Obes, 2022, ISSN 0307-0565
Editor: Nature Publishing Group
DOI: 10.1038/s41366-022-01123-1

Glucose- and Bile Acid-Stimulated Secretion of Gut Hormones in the Isolated Perfused Intestine Is Not Impaired in Diet-Induced Obese Mice.

Autores: Hunt JE, Holst JJ, Jepsen SL.
Publicado en: Frontiers in Endocrinoly (Lausanne), 2022, ISSN 1664-2392
Editor: Lausanne
DOI: 10.3389/fendo.2022.884501

Colonic lactulose fermentation has no impact on glucagon-like peptide-1 and peptide-YY secretion in healthy young men.

Autores: C. Christiansen; Simon Veedfald; Simon Veedfald; Bolette Hartmann; Astrid Marie Gauguin; Søren Møller; Søren Møller; Thomas Moritz; Sten Madsbad; Jens J. Holst
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 1, 2022, Página(s) 77-87, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgab666

Ghrelin Does Not Directly Stimulate Secretion of Glucagon-like Peptide-1.

Autores: Sara L. Jepsen; Esben Thyssen Vestergaard; Pierre Larraufie; Fiona M. Gribble; Frank Reimann; Jens Otto Lunde Jørgensen; Jens J. Holst; Rune E. Kuhre
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 1, 2019, Página(s) 266–275, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgz046

New Lessons from the gut: Studies of the role of gut peptides in weight loss and diabetes resolution after gastric bypass and sleeve gastrectomy

Autores: Jens Juul Holst, Sten Madsbad, Kirstine Nyvold Bojsen-Mller, Carsten Dirksen, Maria Svane
Publicado en: Peptides, Edición 176, 2024, Página(s) 171199, ISSN 0196-9781
Editor: Elsevier BV
DOI: 10.1016/j.peptides.2024.171199

Effect of Meal Texture on Postprandial Glucose Excursions and Gut Hormones after Roux-en-Y Gastric Bypass and Sleeve Gastrectomy

Autores: Nora Hedbäck, Morten Hindsø, Kirstine Nyvold Bojsen-Møller, Adelaide Elise Kjær Linddal, Nils Bruun Jørgensen, Carsten Dirksen, Andreas Møller, Viggo Bjerregaard Kristiansen, Bolette Hartmann, Jens Juul Holst, Maria Saur Svane, Sten Madsbad
Publicado en: Frontiers in Nutrition, 2022, ISSN 2296-861X
Editor: Frontier
DOI: 10.3389/fnut.2022.889710

On the relationship between glucose absorption and glucose-stimulated secretion of GLP-1, neurotensin, and PYY from different intestinal segments in the rat

Autores: Rune E. Kuhre, Charlotte B. Christiansen, Monika Y. Saltiel, Nicolai J. Wewer Albrechtsen, Jens J. Holst
Publicado en: Physiological Reports, Edición 5/23, 2017, Página(s) e13507, ISSN 2051-817X
Editor: Wiley Periodicals, Inc.
DOI: 10.14814/phy2.13507

The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

Autores: Charlotte Bayer Christiansen, Maria Buur Nordskov Gabe, Berit Svendsen, Lars Ove Dragsted, Mette Marie Rosenkilde, Jens Juul Holst
Publicado en: American Journal of Physiology-Gastrointestinal and Liver Physiology, Edición 315/1, 2018, Página(s) G53-G65, ISSN 0193-1857
Editor: American Physiological Society
DOI: 10.1152/ajpgi.00346.2017

Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas

Autores: Rune E. Kuhre, Nicolai J. Wewer Albrechtsen, Olav Larsen, Sara L. Jepsen, Emilie Balk-Møller, Daniel B. Andersen, Carolyn F. Deacon, Kristina Schoonjans, Frank Reimann, Fiona M. Gribble, Reidar Albrechtsen, Bolette Hartmann, Mette M. Rosenkilde, Jens J. Holst
Publicado en: Molecular Metabolism, Edición 11, 2018, Página(s) 84-95, ISSN 2212-8778
Editor: Elsevier GmbH
DOI: 10.1016/j.molmet.2018.03.007

Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss

Autores: Jens Juul Holst, Sten Madsbad, Kirstine N. Bojsen-Møller, Maria Saur Svane, Nils Bruun Jørgensen, Carsten Dirksen, Christoffer Martinussen
Publicado en: Surgery for Obesity and Related Diseases, Edición 14/5, 2018, Página(s) 708-714, ISSN 1550-7289
Editor: Elsevier BV
DOI: 10.1016/j.soard.2018.03.003

Neuromedin U Does Not Act as a Decretin in Rats

Autores: Rune Ehrenreich Kuhre, Charlotte Bayer Christiansen, Seyed Mojtaba Ghiasi, Maria Buur Nordskov Gabe, Patricia Almine Skat-Rørdam, Ida Marie Modvig, Thomas Mandrup-Poulsen, Reidar Albrechtsen, Mette Marie Rosenkilde, Bolette Hartmann, Nicolai Jacob Wewer Albrechtsen, Jens Juul Holst
Publicado en: Cell Metabolism, Edición 29/3, 2019, Página(s) 719-726.e5, ISSN 1550-4131
Editor: Cell Press
DOI: 10.1016/j.cmet.2018.10.008

Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

Autores: Nicolai J. Wewer Albrechtsen, Philipp E. Geyer, Sophia Doll, Peter V. Treit, Kirstine N. Bojsen-Møller, Christoffer Martinussen, Nils B. Jørgensen, Signe S. Torekov, Florian Meier, Lili Niu, Alberto Santos, Eva C. Keilhauer, Jens J. Holst, Sten Madsbad, Matthias Mann
Publicado en: Cell Systems, Edición 7/6, 2018, Página(s) 601-612.e3, ISSN 2405-4712
Editor: Cell Press
DOI: 10.1016/j.cels.2018.10.012

Postprandial Nutrient Handling and Gastrointestinal Hormone Secretion After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy

Autores: Maria S. Svane, Kirstine N. Bojsen-Møller, Christoffer Martinussen, Carsten Dirksen, Jan L. Madsen, Søren Reitelseder, Lars Holm, Jens F. Rehfeld, Viggo B. Kristiansen, Gerrit van Hall, Jens J. Holst, Sten Madsbad
Publicado en: Gastroenterology, Edición 156/6, 2019, Página(s) 1627-1641.e1, ISSN 0016-5085
Editor: W. B. Saunders Co., Ltd.
DOI: 10.1053/j.gastro.2019.01.262

Bile acids drive colonic secretion of glucagon-like-peptide 1 and peptide-YY in rodents

Autores: Charlotte Bayer Christiansen, Samuel Addison Jack Trammell, Nicolai Jacob Wewer Albrechtsen, Kristina Schoonjans, Reidar Albrechtsen, Matthew Paul Gillum, Rune Ehrenreich Kuhre, Jens Juul Holst
Publicado en: American Journal of Physiology-Gastrointestinal and Liver Physiology, Edición 316/5, 2019, Página(s) G574-G584, ISSN 0193-1857
Editor: American Physiological Society
DOI: 10.1152/ajpgi.00010.2019

Augmented GLP-1 Secretion as Seen After Gastric Bypass May Be Obtained by Delaying Carbohydrate Digestion

Autores: Christoffer Martinussen, Kristine Nyvold Bojsen-Møller, Carsten Dirksen, Maria Saur Svane, Viggo Bjerregaard Kristiansen, Bolette Hartmann, Jens Juul Holst, Sten Madsbad
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 104/8, 2019, Página(s) 3233-3244, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/jc.2018-02661

Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

Autores: Rune E. Kuhre, Jens J. Holst
Publicado en: Journal of Visualized Experiments, Edición 144, 2019, ISSN 1940-087X
Editor: MYJoVE Corporation
DOI: 10.3791/58533

Mechanisms of action of a carbohydrate-reduced, high-protein diet in reducing the risk of postprandial hypoglycemia after Roux-en-Y gastric bypass surgery.

Autores: Kandel D, Bojsen-Møller KN, Svane MS, Samkani A, Astrup A, Holst JJ, Madsbad S, Krarup T.
Publicado en: Am J Clin Nutr., 2019, ISSN 1938-3207
Editor: American Society for Nutrition
DOI: 10.1093/ajcn/nqy310

GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism.

Autores: Geke Aline Boer; Stacey N Keenan; Paula M. Miotto; Jens J. Holst; Matthew J. Watt
Publicado en: American Journal of Physiology, Edición 1, 2021, ISSN 0193-1849
Editor: American Physiological Society
DOI: 10.1152/ajpendo.00646.2020

Bilio-enteric flow and plasma concentrations of bile acids after gastric bypass and sleeve gastrectomy

Autores: Eiken A, Fuglsang S, Eiken M, Svane MS, Kuhre RE, Wewer Albrechtsen NJ, Hansen SH, Trammell SAJ, Svenningsen JS, Rehfeld JF, Bojsen-Møller KN, Jørgensen NB, Holst JJ, Madsbad S, Madsen JL, Dirksen C
Publicado en: Int J Obes (Lond), 2020, ISSN 0307-0565
Editor: Nature Publishing Group
DOI: 10.1038/s41366-020-0578-7

Paracrine crosstalk between intestinal L- and D-cells controls secretion of glucagon-like peptide-1 in mice

Autores: Jepsen SL, Grunddal KV, Wewer Albrechtsen NJ, Engelstoft MS, Gabe MBN, Jensen EP, Ørskov C, Poulsen SS, Rosenkilde MM, Pedersen J, Gribble FM, Reimann F, Deacon CF, Schwartz TW, Christ AD, Martin RE, Holst JJ.
Publicado en: Am J Physiol Endocrinol Metab., 2019, ISSN 0193-1849
Editor: American Physiological Society
DOI: 10.1152/ajpendo.00239.2019

Sustained Improvements in Glucose Metabolism Late After Roux-En-Y Gastric Bypass Surgery in Patients with and Without Preoperative Diabetes

Autores: Jørgensen NB, Bojsen-Møller KN, Dirksen C, Martinussen C, Svane MS, Kristiansen VB, Holst JJ, Madsbad S.
Publicado en: Sci Rep., 2019, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-51516-y

Oxyntomodulin and Glicentin May Predict the Effect of Bariatric Surgery on Food Preferences and Weight Loss.

Autores: Mette S. Nielsen; Christian Ritz; Nicolai J. Wewer Albrechtsen; Jens J. Holst; Carel W. le Roux; Carel W. le Roux; Anders Sjödin
Publicado en: The Journal of Clinical Endocrinology & Metabolism, Edición 1, 2020, Página(s) e1064–e1074, ISSN 0021-972X
Editor: The Endocrine Society
DOI: 10.1210/clinem/dgaa061

The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion

Autores: Anna Pii Hjørne; Ida Marie Modvig; Jens Juul Holst
Publicado en: Metabolites, Edición 1, 2022, ISSN 2218-1989
Editor: MDPI
DOI: 10.3390/metabo12050420

Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals.

Autores: Martinussen C, Svane MS, Bojsen-Møller KN, Jensen CZ, Kristiansen VB, Bookout AL, Jørgensen SB, Holst JJ, Wewer Albrechtsen NJ, Madsbad S, Kuhre RE.
Publicado en: Am J Physiol Endocrinol Metab, 2021, ISSN 1548-9213
Editor: American Physiological Society
DOI: 10.1152/ajpendo.00190.2021

Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors.

Autores: Ida M. Modvig; Rune E. Kuhre; Jens J. Holst
Publicado en: Physiological Reports, Vol 7, Iss 8, Pp n/a-n/a (2019), Edición 1, 2019, ISSN 2051-817X
Editor: Physiological Reports
DOI: 10.14814/phy2.14056

Beta cell function and sensitivity to incretins before and after Rouxen-Y gastric bypass in patients with type 2 diabetes

Autores: Svane, MS (Svane, M. S.) [1] ; Hindso, M (Hindso, M.) [1] ; Martinussen, C (Martinussen, C.) [1] ; Dirksen, C (Dirksen, C.) [1] ; Jorgensen, NB (Jorgensen, N. B.) [1] ; Hartmann, B (Hartmann, B.) [2] ; Kristiansen, VB (Kristiansen, V. B.) [1] ; Holst, JJ (Holst, J. J.) [2] ; Bojsen-Moller, KN (Bojsen-Moller, K. N.) [1] ; Madsbad, S (Madsbad, S.
Publicado en: 2022
Editor: EASD annual meeting 2022

Effect of Ghrelin on Glucose Tolerance after Sleeve Gastrectomy

Autores: Hedback, N (Hedback, Nora) ; Dichman, ML (Dichman, Marie-Louise) ; Dirksen, C (Dirksen, Carsten) ; Bojsen-Moller, KN (Bojsen-Moller, Kirstine N.) ; Jorgensen, NB (Jorgensen, Nils B.) ; Hindso, MG (Hindso, Morten G.) ; Kristiansen, VB (Kristiansen, Viggo B.) ; Holst, JJ (Holst, Jens J.) ; Svane, MS (Svane, Maria S.) ; Madsbad, S (Madsbad, Sten, Sr.)
Publicado en: 2022
Editor: EASD annual meeting

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